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RECOMBINASE POLYMERASE-AMPLIFICATION

  • Recombinase polymerase amplification
  • Alternative to the polymerase chain reaction

    Recombinase polymerase amplification (RPA) is a single tube, isothermal alternative to the polymerase chain reaction (PCR). By adding a reverse transcriptase

    Recombinase polymerase amplification

    Recombinase_polymerase_amplification

  • Thermostable DNA polymerase
  • DNA polymerases that originate from thermophiles

    DNA polymerases used in isothermal DNA amplification, e.g. in loop-mediated isothermal amplification, multidisplacement amplification, recombinase polymerase

    Thermostable DNA polymerase

    Thermostable DNA polymerase

    Thermostable_DNA_polymerase

  • Variants of PCR
  • Various uses and techniques of polymerase chain reaction in the laboratory

    displacement amplification (SDA) are isothermal, replicating DNA at a constant temperature using a polymerase and nicking enzyme. Recombinase Polymerase Amplification

    Variants of PCR

    Variants_of_PCR

  • Sickle cell disease
  • Medical condition

    amplification-refractory mutation system (ARMS) and allele-specific recombinase polymerase amplification. These tests can identify subtypes of sickle cell disease

    Sickle cell disease

    Sickle cell disease

    Sickle_cell_disease

  • NASBA (molecular biology)
  • diagnostic assay for the detection of Zika virus using the recombinase polymerase amplification method". The Journal of General Virology. 99 (8): 1012–1026

    NASBA (molecular biology)

    NASBA_(molecular_biology)

  • Nanodiamond
  • Extremely small diamonds used for their thermal, mechanical and optoelectronic properties

    the signal from background autofluorescence. Combined with recombinase polymerase amplification, nanodiamonds enable single-copy detection of HIV-1 RNA on

    Nanodiamond

    Nanodiamond

    Nanodiamond

  • RPA
  • Topics referred to by the same term

    piloted aircraft Replication protein A Recombinase polymerase amplification, isothermal alternative to the polymerase chain reaction (PCR) Resolvable Private

    RPA

    RPA

  • Cytochrome c
  • Protein found in humans

    2013). "An aptamer-based bio-barcode assay with isothermal recombinase polymerase amplification for cytochrome-c detection and anti-cancer drug screening"

    Cytochrome c

    Cytochrome c

    Cytochrome_c

  • Abingdon Health
  • UK & US manufacturer of diagnostic tests

    isothermal amplification with technologies such as Loop-mediated isothermal amplification (LAMP) or Recombinase polymerase amplification (RPA), for example

    Abingdon Health

    Abingdon_Health

  • Research in management of Ebola
  • tests are under trial: Diagnostics-in-a-Suitcase, based on recombinase polymerase amplification (RPA). The new equipment, about the size of a laptop and

    Research in management of Ebola

    Research in management of Ebola

    Research_in_management_of_Ebola

  • CRISPR activation
  • Type of CRISPR tool

    Polymerase for transcription of the gene(s) targeted by the system. In order for a protein to be made from the gene that encodes it, RNA polymerase must

    CRISPR activation

    CRISPR activation

    CRISPR_activation

  • Epstein–Barr virus
  • Virus of the herpes family

    sensitive detection of Epstein–Barr virus DNA in blood by recombinase aided amplification combined with magnetic beads enrichment". Journal of Virological

    Epstein–Barr virus

    Epstein–Barr virus

    Epstein–Barr_virus

  • Chester L. Sutula
  • American scientist

    tests that use several technologies, such as ELISA, Recombinase Polymerase Amplification (RPA), Polymerase Chain Reaction (PCR), nucleic acid hybridization

    Chester L. Sutula

    Chester_L._Sutula

  • Pal Maliga
  • Plant molecular biologist

    post-transformation excision of marker genes using phage site-specific recombinases. The Maliga team constructed the pPZP Agrobacterium binary vector family

    Pal Maliga

    Pal Maliga

    Pal_Maliga

  • DNA adenine methyltransferase identification
  • Lab technique

    GATCs are amplified in the subsequent PCR. A PCR with primers matching the adaptors is then carried out, leading to the specific amplification of genomic

    DNA adenine methyltransferase identification

    DNA_adenine_methyltransferase_identification

  • Glossary of cellular and molecular biology (M–Z)
  • molecules. Recombinant DNA technology is widely used in genetic engineering. recombinase Any of a class of enzymes united by their ability to catalyze some form

    Glossary of cellular and molecular biology (M–Z)

    Glossary_of_cellular_and_molecular_biology_(M–Z)

  • Sanofi Biogenius Canada
  • Science competition for students in Canada

    "Microfluidic Point-of-Care Device for Diagnosis of HIV via Recombinase Polymerase Amplification." A novel method of HIV detection in developing countries

    Sanofi Biogenius Canada

    Sanofi_Biogenius_Canada

  • Double-strand break repair model
  • Model of DNA repair in biology

    DSB are processed into ssDNA with 3' extensions, which allows RAD51 recombinase (eukaryotic homologue of prokaryotic RecA) to bind to it to form a nucleoprotein

    Double-strand break repair model

    Double-strand break repair model

    Double-strand_break_repair_model

  • Genetic engineering techniques
  • Methods used to change the DNA of organisms

    replicating DNA sequences. Polymerase chain reaction (PCR), developed by Kary Mullis in 1983, allowed small sections of DNA to be amplified (replicated) and aided

    Genetic engineering techniques

    Genetic engineering techniques

    Genetic_engineering_techniques

  • Genomic library
  • Collection of the total genomic DNA from a single organism

    vector molecule. Using a host cell to carry the vector allows for easy amplification and retrieval of specific clones from the library for analysis. There

    Genomic library

    Genomic_library

  • Methods to investigate protein–protein interactions
  • Molecular biology techniques

    by enzymatic ligation, they are amplified via rolling circle amplification using a polymerase. After the amplification reaction, several-hundredfold replication

    Methods to investigate protein–protein interactions

    Methods_to_investigate_protein–protein_interactions

  • Volvereviria
  • Realm of viruses

    techniques that only capture dsDNA viruses. Once rolling circle amplification was implemented to amplify ssDNA genomes, a broader scope of ssDNA virus distribution

    Volvereviria

    Volvereviria

  • No-SCAR genome editing
  • Genome manipulation method

    3' overhangs on the linear DNA. Subsequently, λ beta, a member of a recombinase family, binds to the 3' overhangs and mediates annealing to the complementary

    No-SCAR genome editing

    No-SCAR_genome_editing

  • Mutation
  • Alteration in the nucleotide sequence of a genome

    expression seen during stages of development in model organisms. DNA Recombinase systems like Cre-Lox recombination used in association with promoters

    Mutation

    Mutation

    Mutation

  • Glossary of cellular and molecular biology (0–L)
  • of an amplification reaction. The term is most frequently used to describe the numerous copied fragments that are the products of the polymerase chain

    Glossary of cellular and molecular biology (0–L)

    Glossary_of_cellular_and_molecular_biology_(0–L)

  • DNA repair protein XRCC4
  • Protein found in humans

    referred to as class 1, or a 23 bp spacer, referred to as class 2. A recombinase made up of RAG1 and RAG2 subunits always cleave between these two sites

    DNA repair protein XRCC4

    DNA repair protein XRCC4

    DNA_repair_protein_XRCC4

  • RNA interference
  • Biological process of gene regulation

    S2CID 18460980. Tiscornia G, Tergaonkar V, Galimi F, Verma IM (May 2004). "CRE recombinase-inducible RNA interference mediated by lentiviral vectors". Proceedings

    RNA interference

    RNA interference

    RNA_interference

  • Genetically modified animal
  • Animal that has been genetically modified

    Kumar JP (2017). "FLPing Genes on and off in Drosophila". Site-Specific Recombinases. Methods in Molecular Biology. Vol. 1642. pp. 195–209. doi:10.1007/978-1-4939-7169-5_13

    Genetically modified animal

    Genetically modified animal

    Genetically_modified_animal

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