Reference for RANGAP. Search for RANGAP

AI searches containing RANGAP

RANGAP

RanGAP

RanGAP is a protein involved in the transport of other proteins from the cytosol to the nucleus in eukaryotic cells. In model species such as the yeast

RanGAP

WPP domain

Protein domain

amino acid residues long. The domain is known to direct RanGAP to the nuclear envelope. Non-RanGAP nuclear envelope proteins are also known to encode WPP

WPP domain

WPP_domain

Ran (protein)

GTPase functioning in nuclear transport

GTPase-activity is activated through interaction with Ran GTPase activating protein (RanGAP), facilitated by complex formation with Ran-binding protein (RanBP). GTPase-activation

Ran (protein)

Ran_(protein)

RANBP1

Protein-coding gene in the species Homo sapiens

Characterization of the Ran-RanBP1-RanGAP System: Are RanBP Proteins and the Acidic Tail of RanGAP Required for the Ran-RanGAP GTPase Reaction?". Mol. Cell

RANBP1

Intragenomic conflict

Differential transmission of genes residing in the same genome

main drive locus, a truncated tandem duplication of the gene RanGAP on chromosome 2L (Sd-RanGAP) targets a repetitive array of satellite DNA on chromosome

Intragenomic conflict

Intragenomic_conflict

XPO5

transporting pre-miRNA into the cytoplasm in the process. Once in the cytoplasm, RanGAP hydrolyzes GTP to GDP, causing a conformational change that releases the

XPO5

LRRC73

Human gene

Description E-value 444072 28..254 COG5238, RNA1, Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure

LRRC73

Importin

Protein family

still bound to Ran-GTP. Once in the cytoplasm, Ran-GTP is hydrolysed by RanGAP, forming Ran-GDP, and releasing the two importins for further activity.

Importin

RANBP2

Protein-coding gene in the species Homo sapiens

SP100. Another target for SUMOylation is RanGAP which is the GTPase activating protein for Ran. SUMO-RanGAP interacts with a domain near the carboxyl

RANBP2

SENP1

Protein-coding gene in humans

SENP1 mutant (C603S) in complex with SUMO-1 2iy0: SENP1 (MUTANT) SUMO1 RANGAP 2iy1: SENP1 (MUTANT) FULL LENGTH SUMO1 2iyc: SENP1 NATIVE STRUCTURE 2iyd:

SENP1

GARNL1

Protein-coding gene in the species Homo sapiens

PMC 2755882. PMID 19520869. "Entrez Gene: GARNL1 GTPase activating Rap/RanGAP domain-like 1". Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction

GARNL1

SUMO1

Protein-coding gene in the species Homo sapiens

of human Senp2 in complex with RanGAP1-SUMO-1 2iy0: SENP1 (MUTANT) SUMO1 RANGAP 2iy1: SENP1 (MUTANT) FULL LENGTH SUMO1 2pe6: Non-covalent complex between

SUMO1

RANGAP1

Protein-coding gene in the species Homo sapiens

3UIN, 3UIO, 3UIP, 5D2M, 2IO2, 2IO3 Identifiers Aliases RANGAP1, Fug1, RANGAP, SD, Ran GTPase activating protein 1 External IDs OMIM: 602362; MGI: 103071;

RANGAP1