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A Pro-arrhythmic agent is a chemical, drug, or food that promotes cardiac arrhythmias. Omega 3 fatty acids. Chocolate, Coffee, Tea Caffeine, cocaine,
Proarrhythmic_agent
Heart rhythm medication
myocyte repolarization. Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development
Antiarrhythmic_agent
Chemical compound
name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. Iferanserin Cardiac Arrhythmia
Encainide
Antiarrythmic medication
atrial fibrillation after patients undergo cardioversion, but it has proarrhythmic effects and trials suggest that it may lead to an overall increased
Quinidine
Medical test to record electrical activity within the heart
places. Last, the electrophysiologist may administer various drugs (proarrhythmic agents) to induce arrhythmia (inducibility of VT/VF). If the arrhythmia
Electrophysiology_study
Pharmaceutical study
excess mortality was attributed to proarrhythmic effects of the agents. Class I antiarrhythmics are proarrhythmic during heart ischemia in animals. Cardiac
Cardiac Arrhythmia Suppression Trial
Cardiac_Arrhythmia_Suppression_Trial
Cocaine-like dopamine reuptake inhibitor derived from modafinil
hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk". International Journal of Molecular Sciences. 24 (22) 16261. doi:10
JJC8-088
Experimental drug candidate
agent. The administration of HBI-3000 to isolated heart muscle cells demonstrated the potential to improve arrhythmias while having low proarrhythmic
HBI-3000
Chemical compound
istaroxime may permit cytosolic calcium accumulation while avoiding a proarrhythmic state. Proposed mechanisms for istaroxime's antiarrhythmic effect include
Istaroxime
Medical condition
used. However, the options for antiarrhythmic agents are limited because certain agents can be proarrhythmic in the setting of myocardial dysfunction in
Tachycardia-induced cardiomyopathy
Tachycardia-induced_cardiomyopathy
Chemical compound
according to periodical ligand binding: implications for antiarrhythmic and proarrhythmic efficacy". Journal of Cardiovascular Pharmacology. 15 (6): 998–1009
Prajmaline
Chemical compound
Channel-blocking Profile of the Novel Combined Ion Channel Blocker AZD1305 and Its Proarrhythmic Potential Versus Dofetilide in the Methoxamine-sensitized Rabbit in
AZD1305
Antiarrythmic agent
however, they often have a narrow therapeutic index and can also be proarrhythmic. Wolff–Parkinson–White syndrome (WPW) is a pre-excitation syndrome in
Lorcainide
the simulations, several aspects can be investigated to identify the proarrhythmicity of a new pharmacological compound. The typical changes, known as repolarization
Pharmacological cardiotoxicity
Pharmacological_cardiotoxicity
Several medications that disrupt movement of K+ ions
Mohammad (eds.), Antiarrhythmic Drugs: Mechanisms of Antiarrhythmic and Proarrhythmic Actions, Springer Berlin Heidelberg, pp. 92–105, doi:10.1007/978-3-642-85624-2_6
Potassium_channel_blocker
Compounds that inhibit the activity of DNA topoisomerases
Chattipakorn SC, Chattipakorn N (January 2020). "Doxorubicin and its proarrhythmic effects: A comprehensive review of the evidence from experimental and
Topoisomerase_inhibitor
American physiologist (born 1954)
Omega-3 Polyunsaturated Fatty Acids on Cardiac Rhythm: Antiarrhythmic, Proarrhythmic, Both or Neither? (editor). Frontiers. 2013. ISBN 978-2889190881. Billman
George_Billman
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