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PROARRHYTHMIC AGENT

  • Proarrhythmic agent
  • A Pro-arrhythmic agent is a chemical, drug, or food that promotes cardiac arrhythmias. Omega 3 fatty acids. Chocolate, Coffee, Tea Caffeine, cocaine,

    Proarrhythmic agent

    Proarrhythmic_agent

  • Antiarrhythmic agent
  • Heart rhythm medication

    myocyte repolarization. Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development

    Antiarrhythmic agent

    Antiarrhythmic agent

    Antiarrhythmic_agent

  • Encainide
  • Chemical compound

    name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. Iferanserin Cardiac Arrhythmia

    Encainide

    Encainide

    Encainide

  • Quinidine
  • Antiarrythmic medication

    atrial fibrillation after patients undergo cardioversion, but it has proarrhythmic effects and trials suggest that it may lead to an overall increased

    Quinidine

    Quinidine

    Quinidine

  • Electrophysiology study
  • Medical test to record electrical activity within the heart

    places. Last, the electrophysiologist may administer various drugs (proarrhythmic agents) to induce arrhythmia (inducibility of VT/VF). If the arrhythmia

    Electrophysiology study

    Electrophysiology study

    Electrophysiology_study

  • Cardiac Arrhythmia Suppression Trial
  • Pharmaceutical study

    excess mortality was attributed to proarrhythmic effects of the agents. Class I antiarrhythmics are proarrhythmic during heart ischemia in animals. Cardiac

    Cardiac Arrhythmia Suppression Trial

    Cardiac_Arrhythmia_Suppression_Trial

  • JJC8-088
  • Cocaine-like dopamine reuptake inhibitor derived from modafinil

    hERG Activation by Its Blocker: A Mechanism to Reduce Drug-Induced Proarrhythmic Risk". International Journal of Molecular Sciences. 24 (22) 16261. doi:10

    JJC8-088

    JJC8-088

    JJC8-088

  • HBI-3000
  • Experimental drug candidate

    agent. The administration of HBI-3000 to isolated heart muscle cells demonstrated the potential to improve arrhythmias while having low proarrhythmic

    HBI-3000

    HBI-3000

    HBI-3000

  • Istaroxime
  • Chemical compound

    istaroxime may permit cytosolic calcium accumulation while avoiding a proarrhythmic state. Proposed mechanisms for istaroxime's antiarrhythmic effect include

    Istaroxime

    Istaroxime

    Istaroxime

  • Tachycardia-induced cardiomyopathy
  • Medical condition

    used. However, the options for antiarrhythmic agents are limited because certain agents can be proarrhythmic in the setting of myocardial dysfunction in

    Tachycardia-induced cardiomyopathy

    Tachycardia-induced_cardiomyopathy

  • Prajmaline
  • Chemical compound

    according to periodical ligand binding: implications for antiarrhythmic and proarrhythmic efficacy". Journal of Cardiovascular Pharmacology. 15 (6): 998–1009

    Prajmaline

    Prajmaline

    Prajmaline

  • AZD1305
  • Chemical compound

    Channel-blocking Profile of the Novel Combined Ion Channel Blocker AZD1305 and Its Proarrhythmic Potential Versus Dofetilide in the Methoxamine-sensitized Rabbit in

    AZD1305

    AZD1305

    AZD1305

  • Lorcainide
  • Antiarrythmic agent

    however, they often have a narrow therapeutic index and can also be proarrhythmic. Wolff–Parkinson–White syndrome (WPW) is a pre-excitation syndrome in

    Lorcainide

    Lorcainide

    Lorcainide

  • Pharmacological cardiotoxicity
  • the simulations, several aspects can be investigated to identify the proarrhythmicity of a new pharmacological compound. The typical changes, known as repolarization

    Pharmacological cardiotoxicity

    Pharmacological cardiotoxicity

    Pharmacological_cardiotoxicity

  • Potassium channel blocker
  • Several medications that disrupt movement of K+ ions

    Mohammad (eds.), Antiarrhythmic Drugs: Mechanisms of Antiarrhythmic and Proarrhythmic Actions, Springer Berlin Heidelberg, pp. 92–105, doi:10.1007/978-3-642-85624-2_6

    Potassium channel blocker

    Potassium channel blocker

    Potassium_channel_blocker

  • Topoisomerase inhibitor
  • Compounds that inhibit the activity of DNA topoisomerases

    Chattipakorn SC, Chattipakorn N (January 2020). "Doxorubicin and its proarrhythmic effects: A comprehensive review of the evidence from experimental and

    Topoisomerase inhibitor

    Topoisomerase_inhibitor

  • George Billman
  • American physiologist (born 1954)

    Omega-3 Polyunsaturated Fatty Acids on Cardiac Rhythm: Antiarrhythmic, Proarrhythmic, Both or Neither? (editor). Frontiers. 2013. ISBN 978-2889190881. Billman

    George Billman

    George_Billman

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