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PCAF

  • PCAF
  • Protein-coding gene in humans

    P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with

    PCAF

    PCAF

    PCAF

  • Pentecostal Churches of the Apostolic Faith
  • Oneness Pentecostal denomination

    (PCAFI), founded as Pentecostal Churches of the Apostolic Faith Association (PCAF), is a Oneness Pentecostal Christian denomination headquartered in Louisville

    Pentecostal Churches of the Apostolic Faith

    Pentecostal_Churches_of_the_Apostolic_Faith

  • Histone acetyltransferase
  • Enzymes that catalyze acyl group transfer from acetyl-CoA to histones

    roles. The Gcn5-related N-acetyltransferase (GNAT) family includes Gcn5, PCAF, Hat1, Elp3, Hpa2, Hpa3, ATF-2, and Nut1. These HATs are generally characterized

    Histone acetyltransferase

    Histone acetyltransferase

    Histone_acetyltransferase

  • HealthRight International
  • US-based non-profit organization

    allowed PCAF to incorporate its vast knowledge and expertise in global mental health across HealthRight's current and future programs. Since 2018, PCAF has

    HealthRight International

    HealthRight_International

  • Histone acetylation and deacetylation
  • Biological processes used in gene regulation

    ADA, and A2 complexes, Gcn5L, p300/CREB-binding protein associated factor (PCAF), Elp3, HPA2 and HAT1. Major features of the GNAT family include HAT domains

    Histone acetylation and deacetylation

    Histone acetylation and deacetylation

    Histone_acetylation_and_deacetylation

  • Histone deacetylase
  • Class of enzymes important in regulating DNA transcription

    Acetylation of PTEN by the histone acetyltransferase p300/CBP-associated factor (PCAF) can repress its activity; on the converse, deacetylation of PTEN by SIRT1

    Histone deacetylase

    Histone deacetylase

    Histone_deacetylase

  • Department of Agriculture (Philippines)
  • Executive department of the Philippine government

    Philippine Carabao Center (PCC) Philippine Council for Agriculture and Fishery (PCAF) Philippine Center for Postharvest Development and Mechanization (PHilMech)

    Department of Agriculture (Philippines)

    Department of Agriculture (Philippines)

    Department_of_Agriculture_(Philippines)

  • P53
  • Mammalian protein found in humans

    of cofactors. Pin1 enhances conformational changes in p53, while p300 and PCAF acetylate the C-terminus, exposing the DNA-binding domain and enhancing transcriptional

    P53

    P53

    P53

  • TAF5L
  • Protein-coding gene in the species Homo sapiens

    This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than

    TAF5L

    TAF5L

    TAF5L

  • Somalia affair
  • Controversy about the Canadian military in Somalia

    Donna. The Parliamentary Inquiry into the Canadian Peace Mission in Somalia. PCAF Workshop, Brussels, July 12–14, 2002. Geneva Centre for the Democratic Control

    Somalia affair

    Somalia_affair

  • Chromosome 3
  • Human chromosome

    NPRL2: Nitrogen permease regulator 2-like protein OXTR: oxytocin receptor PCAF: acetyltransferase activity PHF7 encoding protein PHD finger protein 7 PRICKLE2:

    Chromosome 3

    Chromosome 3

    Chromosome_3

  • TBP-associated factor
  • Protein domains

    has three SAGA-like complexes: PCAF, TFTC (TBP-free TAF-containing complex), and STAGA (SPT3-TAF9-GCN5L acetylase). PCAF (GCN5) and KAT2A (GCN5L) are two

    TBP-associated factor

    TBP-associated factor

    TBP-associated_factor

  • Histone octamer
  • 8-protein complex forming the core of nucleosomes

    distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates". The Journal of Biological Chemistry. 274

    Histone octamer

    Histone octamer

    Histone_octamer

  • Mdm2
  • Protein-coding gene in humans

    FKBP3, FOXO4, GNL3, HDAC1, HIF1A, HTATIP, IGF1R, MDM4, NUMB, P16, P53, P73, PCAF, PSMD10, PSME3, RPL5, RPL11, PML, RPL26, RRM2B, RYBP, TBP, and UBC. Mdm2

    Mdm2

    Mdm2

    Mdm2

  • Sirtuin
  • Enzyme

    H1K26ac, H4K16ac Hif-1α, HIF-2α, MYC, P53, BRCA1, FOXO3A, MyoD, Ku70, PPARγ, PCAF, Suv39h1, TGFB1, WRN, NBS1 Neurodegenerative diseases, Cancer: acute myeloid

    Sirtuin

    Sirtuin

    Sirtuin

  • Myc
  • Family of regulator genes

    EP400 GTF2I HTATIP let-7 MAPK1 MAPK8 MAX MLH1 MYCBP2 MYCBP NMI NFYB NFYC P73 PCAF PFDN5 RuvB-like 1 SAP130 SMAD2 SMAD3 SMARCA4 SMARCB1 SUPT3H TIAM1 TADA2L

    Myc

    Myc

  • IRF2
  • Protein-coding gene in the species Homo sapiens

    regulatory factors IRF2 has been shown to interact with BRD7, EP300 and PCAF. GRCh38: Ensembl release 89: ENSG00000168310 – Ensembl, May 2017 GRCm38:

    IRF2

    IRF2

    IRF2

  • Ming-Ming Zhou
  • Chinese-American scientist

    mechanism-driven research led to the discovery of the HIV Tat/human co-activator PCAF interaction as a potential novel anti-HIV therapy target. His group has developed

    Ming-Ming Zhou

    Ming-Ming Zhou

    Ming-Ming_Zhou

  • Apostolic Assemblies of Christ
  • Ministries. Baker Books. ISBN 978-1-4934-0640-1. In 1970, G. M. Boone exited the PCAF over administrative differences and confusion surrounding the organization's

    Apostolic Assemblies of Christ

    Apostolic_Assemblies_of_Christ

  • EP300
  • Protein-coding gene in the species Homo sapiens

    Wallberg AE, Pedersen K, Lendahl U, Roeder RG (November 2002). "p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates

    EP300

    EP300

    EP300

  • Transcription coregulator
  • Proteins that help regulate transcription

    NCOA4 NCOA5 (NCOA5) NCOA6 (NCOA6) NCOA7 (NCOA7) p300 EP300 PCAF (p300/CBP associating factor) PCAF PGC1 (proliferator activated receptor gamma coactivator

    Transcription coregulator

    Transcription_coregulator

  • Transformation/transcription domain-associated protein
  • Protein-coding gene in the species Homo sapiens

    domain-associated protein has been shown to interact with: ACTL6A, EP400, MAX, Myc, PCAF, SUPT3H, and TAF9. and GRCh38: Ensembl release 89: ENSG00000196367 – Ensembl

    Transformation/transcription domain-associated protein

    Transformation/transcription domain-associated protein

    Transformation/transcription_domain-associated_protein

  • Philippine Fiber Industry Development Authority
  • consolidation of FIDA and CODA) Jurisdiction Philippines Headquarters DA-PCAF Bldg., Department of Agriculture Compound, Elliptical Road, Diliman, Quezon

    Philippine Fiber Industry Development Authority

    Philippine Fiber Industry Development Authority

    Philippine_Fiber_Industry_Development_Authority

  • USF1
  • Protein-coding gene in the species Homo sapiens

    5' DNase I hypersensitive site HS4 and recruit an H3 acetyltransferase, PCAF, which blocks the heterochromatin spread into the β-globin locus. USF is

    USF1

    USF1

    USF1

  • Amino acid response
  • Mechanism triggered in mammalian cells by amino acid starvation

    that it requires RAG-GTPases and the lysosomal protein complex regulator. PCAF is recruited specifically to the CHOP amino acid response element to enhance

    Amino acid response

    Amino_acid_response

  • Catenin beta-1
  • Mammalian protein found in humans

    HER2/neu, HNF4A, IKK2, LEF1 including transgenically, MAGI1, MUC1, NR5A1, PCAF, PHF17, Plakoglobin, PTPN14, PTPRF, PTPRK (PTPkappa), PTPRT (PTPrho), PTPRU

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • IRF1
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: CHIP GAGE HSP70 / HSP90 IRF8 KPNA2 MYD88 PCAF STAT1 TAT VEGFR2 REDD2 IRF2 Interferon regulatory factors GRCm38: Ensembl

    IRF1

    IRF1

    IRF1

  • RBPJ
  • Protein-coding gene in the species Homo sapiens

    demonstrate Notch1 signaling. RBPJ has been shown to interact with: NOTCH1 NCOR2, PCAF, SND1, SNW1, SOX18, and HIF1a. GRCh38: Ensembl release 89: ENSG00000168214

    RBPJ

    RBPJ

    RBPJ

  • KAT5
  • Protein-coding gene in the species Homo sapiens

    2004). "The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60". Molecular and Cellular Biology. 24 (24): 10826–34. doi:10.1128/MCB

    KAT5

    KAT5

    KAT5

  • Bromodomain
  • Protein domain

    and other forms of cancer. Histone acetyltransferases, including EP300 and PCAF, have bromodomains in addition to acetyl-transferase domains. Not considered

    Bromodomain

    Bromodomain

    Bromodomain

  • KAT2A
  • Protein-coding gene in the species Homo sapiens

    between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5". J. Biol. Chem. 275 (22): 17211–20. doi:10.1074/jbc.M000909200

    KAT2A

    KAT2A

    KAT2A

  • Twist-related protein 1
  • Transcription factor protein

    Twist transcription factor has been shown to interact with EP300, TCF3 and PCAF. Transcription factor TWIST2 GRCh38: Ensembl release 89: ENSG00000122691

    Twist-related protein 1

    Twist-related protein 1

    Twist-related_protein_1

  • Enhancer RNA
  • Type of non-coding RNA molecule

    AK, Caputo L, Percipalle P (October 2008). "The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription". Molecular

    Enhancer RNA

    Enhancer RNA

    Enhancer_RNA

  • CREB-binding protein
  • Nuclear protein that binds to CREB

    GATA1 GR hATF4 HNF-1 Hif-1α Ku70   MDM2 MLL MyoD NF-κB p53 p73 Parp1 pCREB pCAF PCNA Pit1 RAR RXR SCRAP SMAD   Src1 Srebp1c STAT1 STAT2 STAT3 Sumo T3R[22]

    CREB-binding protein

    CREB-binding protein

    CREB-binding_protein

  • USP22
  • Protein-coding gene in the species Homo sapiens

    Faiola F, Xu M, Pan S, Martinez E (December 2008). "Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that

    USP22

    USP22

    USP22

  • Heat shock protein 47
  • Protein-coding gene in the species Homo sapiens

    Stamatoyannopoulos G (March 2002). "Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2". The Journal of Biological Chemistry. 277

    Heat shock protein 47

    Heat shock protein 47

    Heat_shock_protein_47

  • TAF9
  • Protein-coding gene in the species Homo sapiens

    Yang XJ, Howard BH, Qin J, Nakatani Y (1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2

    TAF9

    TAF9

    TAF9

  • BRCA2
  • Gene known for its role in breast cancer

    BRCC3, BUB1B, CREBBP, C11orf30, FANCD2, FANCG, FLNA, HMG20B, P53, PALB2, PCAF, PLK1, RAD51, RPA1, SHFM1 and SMAD3. BRCA2 contains a number of 39 amino

    BRCA2

    BRCA2

    BRCA2

  • IRF7
  • Protein-coding gene in the species Homo sapiens

    regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding". The Journal of Biological Chemistry. 277 (51):

    IRF7

    IRF7

    IRF7

  • Climate finance in Nigeria
  • Climate financing in Nigeria

    for Africa have adhered to the Partnership for Carbon Accounting Finance (PCAF) standards to promote emissions transparency. Despite this, according to

    Climate finance in Nigeria

    Climate finance in Nigeria

    Climate_finance_in_Nigeria

  • P300-CBP coactivator family
  • Protein family

    JE, Wang C, Brindle PK, Dent SY, Ge K (Jan 2011). "Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation"

    P300-CBP coactivator family

    P300-CBP coactivator family

    P300-CBP_coactivator_family

  • MAML1
  • Protein-coding gene in the species Homo sapiens

    (Drosophila)". Wallberg AE, Pedersen K, Lendahl U, Roeder RG (Nov 2002). "p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates

    MAML1

    MAML1

    MAML1

  • Microtubule associated scaffold protein 2
  • Protein-coding gene in the species Homo sapiens

    microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability

    Microtubule associated scaffold protein 2

    Microtubule associated scaffold protein 2

    Microtubule_associated_scaffold_protein_2

  • HNF1A
  • Protein-coding gene in humans

    HNF1A has been shown to interact with: CREB-binding protein and EP300, PCAF, PCBD1, RAC3, Src, DCoH Hepatocyte nuclear factors Maturity onset diabetes

    HNF1A

    HNF1A

    HNF1A

  • HMGN2
  • Protein-coding gene in the species Homo sapiens

    M, et al. (1999). "Specific acetylation of chromosomal protein HMG-17 by PCAF alters its interaction with nucleosomes". Mol. Cell. Biol. 19 (5): 3466–73

    HMGN2

    HMGN2

    HMGN2

  • BLOC1S1
  • Protein-coding gene in the species Homo sapiens

    Ogryzko VV, Kotani T, Zhang X, et al. (1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2

    BLOC1S1

    BLOC1S1

    BLOC1S1

  • MECOM
  • Protein-coding gene in the species Homo sapiens

    CREB binding protein CTBP1 HDAC1 Mothers against decapentaplegic homolog 3 PCAF GRCh38: Ensembl release 89: ENSG00000085276 – Ensembl, May 2017 GRCm38: Ensembl

    MECOM

    MECOM

    MECOM

  • Transcription initiation protein SPT3 homolog
  • Protein-coding gene in the species Homo sapiens

    Howard BH, Qin J, Nakatani Y (Jul 1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2

    Transcription initiation protein SPT3 homolog

    Transcription initiation protein SPT3 homolog

    Transcription_initiation_protein_SPT3_homolog

  • Global Alliance for Banking on Values
  • Ethical banking association

    supports initiatives such as the Partnership for Carbon Accounting Financials (PCAF), and in 2024 several member banks endorsed the Fossil Fuel Non-Proliferation

    Global Alliance for Banking on Values

    Global_Alliance_for_Banking_on_Values

  • Tapas Kumar Kundu
  • Indian molecular biologist

    selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF". Molecular Cell. 5 (3): 589–595. doi:10.1016/S1097-2765(00)80452-9. PMID 10882143

    Tapas Kumar Kundu

    Tapas_Kumar_Kundu

  • TAF6L
  • Protein-coding gene in the species Homo sapiens

    is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex

    TAF6L

    TAF6L

    TAF6L

  • CSRP3
  • Protein-coding gene in humans

    acetylated/deacetylated at the position 69 lysine residue (K69), by acetyltransferase (PCAF) and histone deacetylase 4 (HDAC4), respectively. In myocytes, MLP has the

    CSRP3

    CSRP3

    CSRP3

  • KLF13
  • Protein found in humans

    been shown to interact with CREB-binding protein, Heat shock protein 47 and PCAF. Kruppel-like factors ENSG00000275746 GRCh38: Ensembl release 89: ENSG00000169926

    KLF13

    KLF13

    KLF13

  • TCF3
  • Protein-coding gene in the species Homo sapiens

    CREBBP, ELK3, EP300, ID3, LDB1, LMX1A, LYL1, MAPKAPK3, MyoD, Myogenin, PCAF, TAL1 TWIST1, and UBE2I. GRCh38: Ensembl release 89: ENSG00000071564 – Ensembl

    TCF3

    TCF3

    TCF3

  • TADA3L
  • Protein-coding gene in the species Homo sapiens

    a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor

    TADA3L

    TADA3L

    TADA3L

  • POLE4
  • Protein-coding gene in the species Homo sapiens

    Wang YL, Faiola F, Xu M, Pan S, Martinez E (2008). "Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that

    POLE4

    POLE4

    POLE4

  • TADA2L
  • Protein-coding gene in the species Homo sapiens

    a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms

    TADA2L

    TADA2L

    TADA2L

  • CSRP2BP
  • Protein-coding gene in humans

    Faiola F, Xu M, Pan S, Martinez E (December 2008). "Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that

    CSRP2BP

    CSRP2BP

    CSRP2BP

  • UHRF1
  • Protein-coding gene in the species Homo sapiens

    Tudor domains, where methylation and acetylation enzymes such as SET7, SET8, PCAF, and p300 have been reported to interact with UHRF1. Other PTMs, including

    UHRF1

    UHRF1

    UHRF1

  • Nuclear receptor coactivator 1
  • Protein-coding gene in the species Homo sapiens

    protein, Cyclin D1, Estrogen receptor alpha, Glucocorticoid receptor, NFKB1, PCAF, PPARGC1A, Peroxisome proliferator-activated receptor alpha, SNW1, STAT3

    Nuclear receptor coactivator 1

    Nuclear receptor coactivator 1

    Nuclear_receptor_coactivator_1

  • TAF12
  • Protein-coding gene in the species Homo sapiens

    Yang XJ, Howard BH, Qin J, Nakatani Y (1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2

    TAF12

    TAF12

    TAF12

  • POLR2A
  • Protein-coding gene in the species Homo sapiens

    interact with: BRCA1, CREBBP, CTDP1, CDK8, GTF2B, GTF2F1, GTF2H4, MED21, MED26, PCAF, POLR2C, POLR2E, POLR2H, POLR2L, PQBP1, SMARCA2, SMARCA4 SMARCB1, SMYD3,

    POLR2A

    POLR2A

    POLR2A

  • TAF10
  • Protein-coding gene in the species Homo sapiens

    Yang XJ, Howard BH, Qin J, Nakatani Y (1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2

    TAF10

    TAF10

    TAF10

  • 2009 National Cheerleading Championship
  • Fourth Philippines National Cheerleading Championship

    28 (13) 169 12 Bangkal High School Bangkal Pep Squad 37 51 46 45 34 (78) 135 12 Paco Citizen Academy Foundation PCAF Wizards 30.5 29 30 33 32.5 0 155

    2009 National Cheerleading Championship

    2009_National_Cheerleading_Championship

  • Epigenetics of diabetes type 2
  • Field of study

    monocytes increased recruitment of the HATs CREB-binding protein (CPB) and PCAF, leading to increased histone lysine acetylation at the cyclooxygenase-2

    Epigenetics of diabetes type 2

    Epigenetics_of_diabetes_type_2

  • Island-class patrol boat squadron
  • Military history

    was also designated Commanding Officer, Primary Crew Assembly Facility (PCAF) for the first 16 Island-class patrol boats. Squadron TWO was commissioned

    Island-class patrol boat squadron

    Island-class_patrol_boat_squadron

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