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Protein-coding gene in the species Homo sapiens
downregulated gene 4-like (NEDD4L) or NEDD4-2 is an enzyme (ubiquitin ligase) of the NEDD4 family. In human the protein is encoded by the NEDD4L gene. In mouse the
NEDD4L
Protein-coding gene in the species Homo sapiens
consists of 9 members: NEDD4 (the core topic of this article) NEDD4-2 (or NEDD4L) ITCH SMURF1 SMURF2 WWP1 WWP2 NEDL1 (HECW1) NEDDL2 (HECW2)]. NEDD4 regulates
NEDD4
Medication
kidney function. A single nucleotide polymorphism (SNP) in the protein NEDD4L may impact how amiloride affects a person's blood pressure in cases of hypertension
Amiloride
Protein-coding gene in the species Homo sapiens
precursor cell expressed developmentally downregulated protein 4-like (NEDD4L) E3 ubiquitin-protein ligase Biogrid, InnateDB, Mentha Neural precursor
PRR16
Protein
HECW1, HECW2 HERC1, HERC2, HERC3, HERC4, HERC5, HERC6 HUWE1, ITCH NEDD4, NEDD4L PPIL2 PRPF19 PIAS1, PIAS2, PIAS3, PIAS4 RANBP2 RNF4, RNF167 RBX1 SMURF1
Ubiquitin_ligase
Q96NY8 10408 NEDD1 HGNC:7723; Q8NHV4 10409 NEDD4 HGNC:7727; P46934 10410 NEDD4L HGNC:7728; Q96PU5 10411 NEDD8 HGNC:7732; Q15843 10412 NEDD9 HGNC:7733; Q14511
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Protein domain
HECW1; HECW2; ITCH; ITSN1; ITSN2; MAP3K20; MCTP1; MCTP2; MTAC2D1; NEDD4; NEDD4L; NEDL1; OTOF; PKN1; PKN2; PKN3; PCLO; PIK3C2A; PIK3C2B; PIK3C2G; PLA2G4A;
C2_domain
Protein-coding gene in the species Homo sapiens
associated with female infertility. SCNN1A has been shown to interact with: NEDD4L, NEDD4, and Ubiquitin C Epithelial sodium channel GRCh38: Ensembl release
SCNN1A
NEDD4L
NEDD4L
NEDD4L
NEDD4L
NEDD4L
NEDD4L
NEDD4L
NEDD4L
NEDD4L