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Diverse collection of blood-related cancers
A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into
Myelodysplastic_syndrome
Tumors that affect the blood, bone marrow, lymph, and lymphatic system
neoplasm, unclassifiable Myelodysplastic syndromes Myelodysplastic syndrome with single lineage dysplasia Myelodysplastic syndrome with ring sideroblasts
Tumors of the hematopoietic and lymphoid tissues
Tumors_of_the_hematopoietic_and_lymphoid_tissues
Cancer of the myeloid line of blood cells
being male, smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. The underlying mechanism
Acute_myeloid_leukemia
Abnormal development, at macroscopic or microscopical level
Dysplasias on a mainly macroscopic scale include hip dysplasia, myelodysplastic syndrome, and multicystic dysplastic kidney. In one of the modern histopathological
Dysplasia
Human disease
This chromosome abnormality is most commonly associated with the myelodysplastic syndrome. It should not be confused with "partial trisomy 5q", though both
Chromosome 5q deletion syndrome
Chromosome_5q_deletion_syndrome
Disease causing insufficient blood cells of all types
overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome". Blood. 100 (5):
Aplastic_anemia
Pair of enantiomers
myeloma, smoldering myeloma, various indolent lymphomas, and myelodysplastic syndromes (MDS). For multiple myeloma, it is a first-line treatment, and
Lenalidomide
Columbia University medical researcher
the Chan Soon-Shiong Professor of Medicine and director of the Myelodysplastic Syndrome (MDS) Center at Columbia University. She has previously held positions
Azra_Raza
Anemia which requires regular blood transfusion
diseases can lead to transfusion-dependent anemia, most notably myelodysplastic syndromes (MDS) and thalassemia. The transfusions alleviate the symptoms
Transfusion-dependent_anemia
Medical condition
other tissues. The syndrome includes as its primary symptoms: serious abnormalities of the blood such as the myelodysplastic syndrome and acute myeloid
Emberger_syndrome
Antibiotic
thrombocytopenia in a patient with chloramphenicol-associated myelodysplastic syndrome". Eur J Haematol. 76 (3): 255–257. doi:10.1111/j.0902-4441.2005
Chloramphenicol
Blood disease in which red blood cells are attacked by the immune system
another specified bone marrow disorder such as aplastic anemia and myelodysplastic syndrome (MDS). Subclinical PNH. PNH abnormalities on flow cytometry without
Paroxysmal nocturnal hemoglobinuria
Paroxysmal_nocturnal_hemoglobinuria
Genetic disease causing anemia, birth defects, and cancers
majority develop cancer, most often acute myelogenous leukemia (AML), myelodysplastic syndrome (MDS), and liver cancer. 90% develop aplastic anemia (the inability
Fanconi_anemia
American television broadcaster (born 1960)
the Women's Basketball Hall of Fame in 2012. Her treatment for myelodysplastic syndrome was chronicled on the program, which earned a 2012 Peabody Award
Robin_Roberts_(newscaster)
Medical condition
failure and halt the progression of malignant transformation toward myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), the most detrimental complications
Shwachman–Diamond_syndrome
Medical condition
pigmentation, nail dystrophy, and leukoplakia of the oral mucosa, and myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), but these components do
Dyskeratosis_congenita
Chemical compound
Vidaza among others, is a medication used for the treatment of myelodysplastic syndrome, myeloid leukemia, and juvenile myelomonocytic leukemia. It is
Azacitidine
Medical condition
deficiency (i.e. MonoMAC or MonoMAC/DCML); Emberger syndrome; Familial myelodysplastic syndrome/acute myeloid leukemia (i.e. familial MDS/AML); Chronic
GATA2_deficiency
Immune disorder in the blood leading to hyperinflammation
and myelodysplastic syndrome.[citation needed] In rheumatic diseases, this syndrome is more often referred to as macrophage activation syndrome (MAS)
Hemophagocytic lymphohistiocytosis
Hemophagocytic_lymphohistiocytosis
Medical diagnostic method
used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and the
International Prognostic Scoring System
International_Prognostic_Scoring_System
Medical condition
be caused either by a genetic disorder or indirectly as part of myelodysplastic syndrome, which can develop into hematological malignancies (especially
Sideroblastic_anemia
Organ dysfunction
aplastic anemia or myelodysplastic syndrome. Inherited marrow failure syndromes include: Ribosomopathies such as Shwachman-Diamond syndrome Telomeropathies
Bone_marrow_failure
American attorney (1939–2019)
stepdaughter. Kirby died on October 2, 2019, due to complications from myelodysplastic syndrome, twenty days before his 80th birthday. Turi, Tim (June 17, 2011)
John_Kirby_(attorney)
American actor (1931–2012)
in remission. Then, in July 2012, doctors diagnosed Hagman with myelodysplastic syndrome (formerly known as preleukemia).[citation needed] Hagman died on
Larry_Hagman
Medical condition
least one type of blood cell. CMML shows characteristics of a myelodysplastic syndrome (MDS); a disorder that produces abnormal-looking blood cells, and
Chronic myelomonocytic leukemia
Chronic_myelomonocytic_leukemia
American scientist and science communicator (1934–1996)
Carl Edward Sagan (/ˈseɪɡən/; SAY-gən; November 9, 1934 – December 20, 1996) was an American astronomer, planetary scientist and science communicator.
Carl_Sagan
American pharmaceutical company
(Revlimid), used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (6% of 2025 revenues); abatacept (Orencia), used to treat autoimmune
Bristol_Myers_Squibb
congenita (DKCX), Treacher Collins syndrome (TCS), Shwachman–Diamond syndrome (SDS) and 5q- myelodysplastic syndrome.(5q- MDS),(cite)(cite) North American
Ribosomopathy
British writer and poet (1916–1990)
November 1990, at the age of 74 of a rare cancer of the blood, myelodysplastic syndrome, in Oxford, and was buried in the cemetery at the Church of St
Roald_Dahl
Medical condition
long-term complications such as hematopoietic clonal disorders (myelodysplastic syndrome, acute myeloid leukemia). Kostmann disease (SCN3), the initial
Severe_congenital_neutropenia
Medical condition
hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome Increased RDW is seen in iron deficiency anemia and decreased or
Anisocytosis
Syndromes
Chilaiditi syndrome Child sexual abuse accommodation syndrome CHILD syndrome childhood myelodysplastic syndrome Childhood tumor syndrome Chinese Restaurant
List_of_syndromes
French fashion designer (1958–2015)
Mid-Wilshire section of Los Angeles. Audigier was diagnosed with myelodysplastic syndrome, a blood cancer, in January 2015. He died on 10 July 2015 at Cedars-Sinai
Christian_Audigier
US Army Medal of Honor recipient (1943–2014)
days before his 71st birthday, in Stanford, California. He had myelodysplastic syndrome. He is buried in Arlington National Cemetery. Combat Infantryman
Jon_R._Cavaiani
American biopharmaceutical company
FibroGen’s Phase 3 MATTERHORN trial evaluating roxadustat in lower-risk myelodysplastic syndrome also failed in 2023. Following the last clinical setback in 2023
Kyntra_Bio
American businessman (1919–2005)
Shirley Temple from December 16, 1950, until his death. He died from myelodysplastic syndrome on August 4, 2005, at his home in Woodside, California, at the
Charles_Alden_Black
Diagnosis classification
dysplasia M9986/3 Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality M9989/3 Myelodysplastic syndrome, NOS Medical classification
International Classification of Diseases for Oncology
International_Classification_of_Diseases_for_Oncology
American biotechnology company
granted fast track status by the FDA for certain patients with myelodysplastic syndrome. In 2018, Janssen Biotech returned the rights to imetelstat to
Geron_Corporation
Medical condition
Chloromas may occur in patients with a diagnosis of myelodysplastic syndrome (MDS) or myeloproliferative syndromes (MPS) (e.g. chronic myelogenous leukemia (CML)
Myeloid_sarcoma
Form of acute myeloid leukemia
classification. Translocations have been observed. Progression from myelodysplastic syndrome has been reported. Some patients may experience: Fatigue Easy Bruising
Acute_myelomonocytic_leukemia
American news reporter and political analyst (1937 – 2010)
a feature called "Eye on Politics." Henning was diagnosed with myelodysplastic syndrome, a condition in which the bone marrow does not produce enough blood
John_Henning_(journalist)
American businessman (born 1944)
from drug addiction. Diane Bigelow died on February 19, 2020, of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Bigelow has made political
Robert_Bigelow
Insufficient level of copper in the body, leading to anaemia and nervous symptoms
and bone marrow aspirate findings in copper deficiency can mimic myelodysplastic syndrome. Bone marrow aspirate in both conditions may show dysplasia of
Copper_deficiency
Auto-inflammatory syndrome
predisposition towards developing hematologic malignancies, especially myelodysplastic syndrome. On bone marrow examination, people with the disease exhibit abnormal
VEXAS_syndrome
American businessman
Goya de Santo Domingo. After his brother Joseph F. Unanue died of myelodysplastic syndrome in 1998, he became Executive Vice President. Unanue became Goya's
Andy_Unanue
Medical condition
Refractory cytopenia of childhood is a subgroup of myelodysplastic syndrome (MDS), having been added to the World Health Organization classification in
Refractory cytopenia of childhood
Refractory_cytopenia_of_childhood
Digital information reflecting an individual's karyotype
Unclassified ALL is considered to have an intermediate prognosis. Myelodysplastic syndrome (MDS) has remarkable clinical, morphological, and genetic heterogeneity
Virtual_karyotype
Medication
combination anticancer medication used for the treatment of adults with myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML). It is a combination
Decitabine/cedazuridine
Medical condition
reclassification by the World Health Organization, cases that evolved from myelodysplastic syndromes, myeloproliferative neoplasms, chemotherapy for other cancers
Acute_erythroid_leukemia
Medical condition
associated with dyserythropoiesis including megaloblastic anemia, myelodysplastic syndromes, Fanconi anemia and CDA type I & III. Round macrocytes are associated
Macrocytosis
Genetic neurological disease
development in patients receiving this gene therapy, including myelodysplastic syndrome and acute myeloid leukemia. The anti-diabetic medication pioglitazone
Adrenoleukodystrophy
Protein-coding gene in the species Homo sapiens
enteropathy (MIRAGE) syndrome. This can lead to loss of chromosome 7 as described for monosomy 7 and myelodysplastic syndrome and leukemia syndrome-2 (M7MLS2).
SAMD9
Expansion of blood cells
the general population will develop a hematologic cancer such as myelodysplastic syndrome (MDS) or AML; it is estimated that just 3 to 4 people per 100,000
Clonal_hematopoiesis
Polish volleyball player (1982–2008)
died of an infection following a bone marrow transplant to treat Myelodysplastic syndrome, which she had suffered from since the age of 17. Agata was born
Agata_Mróz-Olszewska
American actress and singer (born 1958)
When Hagman died on November 23, 2012, due to complications from myelodysplastic syndrome, she was devastated, and attended his funeral. Upon his death,
Charlene_Tilton
Medical condition
acute myelogenous leukemia or chronic myelogenous leukemia and in myelodysplastic syndrome. It has also been described in Filovirus disease. In patients with
Pelger–Huët_anomaly
Pharmaceutical drug
medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. The US Food and Drug Administration (FDA) considers it to be
Luspatercept
Condition or cell change indicating increased cancer risk
undetermined significance, which can progress into multiple myeloma or myelodysplastic syndrome, and cervical dysplasia, which can progress into cervical cancer
Precancerous_condition
Medical condition
thalassemia, sickle cell disease, leukemia, aplastic anemia, or myelodysplastic syndrome, among others. It is diagnosed with a blood transferrin test and
Transfusion_hemosiderosis
Reduced ability of blood to carry oxygen
typical blood smear showing immature and abnormal erythrocytes. Myelodysplastic syndrome Anemia of chronic disease. Chronic inflammation can disrupt iron
Anemia
Indian actor (1932–2005)
Actor award for Meri Jung and Virasat. Puri was diagnosed with myelodysplastic syndrome, a rare form of blood cancer and had undergone brain surgery for
Amrish_Puri
North American blood cancer charitable organization
blood cancer, including Hodgkin's disease, Leukemia, Lymphoma, Myelodysplastic syndrome, Myeloma, and Myeloproliferative neoplasm. Formerly known as the
Blood_Cancer_United
American actor and comedian (1933–2020)
was reported as cardiac arrest, with coronary artery disease and myelodysplastic syndrome as contributing factors. Jamie Lee Curtis and her husband Christopher
Fred_Willard
Chemical compound
(GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Common side effects include
Imatinib
American actress and casting director (1931–2023)
documentary filmmaker; and Julie, an actress. Merlin died from myelodysplastic syndrome at the Los Angeles home of her daughter, Rachel, on October 15
Joanna_Merlin
Abnormally low concentration of neutrophils (a type of white blood cell) in the blood
marrow biopsies can also be used to monitor the development of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) in patients with chronic
Neutropenia
Medical condition
other epithelial cancers such as thyroid and liver cancers, MDS (myelodysplastic syndrome), and MFH (malignant fibrous histiocytoma) are also prevalent among
Werner_syndrome
Overproduction of platelets in the bone marrow
grade 2 reticulin fibrosis (using 0–4 scale) B6. No evidence of a myelodysplastic syndrome no significant dysplasia no cytogenetic abnormalities suggestive
Essential_thrombocythemia
American jazz drummer, percussionist, and composer (1931–2011)
of 80, at New York's Mount Sinai Hospital of complications from myelodysplastic syndrome. CAM Jazz released a box set titled Paul Motian in September 2010
Paul_Motian
American judoka
Grove, Illinois, died on August 27, 2012, from amyloidosis and myelodysplastic syndromes. "US Olympic Judo Teams 1964 to present". Archived from the original
Irwin_Cohen
American actor
in Howard Hawks' Hatari!. After suffering for many months from myelodysplastic syndrome, he died on June 10, 2013, aged 78, in Tulsa, Oklahoma. His interment
Valentin_de_Vargas
Medical condition
Group (COG) JMML study Europe: the European Working Group for Myelodysplastic Syndromes (EWOG-MDS) JMML study The following procedures are used in one
Juvenile myelomonocytic leukemia
Juvenile_myelomonocytic_leukemia
Drug type for epigenetic therapy
and decitabine, are FDA-approved for use in the United States in myelodysplastic syndrome and are being investigated for use in a number of tumors. Two hypomethylating
Hypomethylating_agent
American chemist (1943–2026)
Steigerwald on reducing the size of the quantum dots. Brus died of myelodysplastic syndrome in Hastings-on-Hudson, New York on January 11, 2026, at the age
Louis_E._Brus
Surgical instrument
Fechter, Lenn (2007), One hundred questions and answers about myelodysplastic syndromes, Jones & Bartlett Learning, p. 21, ISBN 978-0-7637-5333-7 "Bone
Jamshidi_needle
Protein-coding gene in humans
cause the chromosome 5q deletion syndrome (5q- syndrome). This syndrome is a unique type of myelodysplastic syndrome characterized by a prolonged disease
PDGFRB
Type of cancer
of myeloid neoplasms, lymphoid neoplasms, myelofibrosis, or the myelodysplastic syndrome. Transient myeloproliferative disease, also termed transient leukemia
Leukemia
President of Panama from 2019 to 2024
part of Copa Airlines. In June 2022, Cortizo was diagnosed with myelodysplastic syndrome. Cortizo is a devout Catholic and often reads the Bible. Sáez,
Laurentino_Cortizo
American composer for film and television (1946–2025)
brother-in-law to actress Tyne Daly and actor Tim Daly. Snow died from myelodysplastic syndrome at his home in Washington, Connecticut, on July 4, 2025, at the
Mark_Snow
Medical condition
Overwhelming infections Lymphoma Myelofibrosis Dyskeratosis congenita Myelodysplastic syndrome Leukemia Leishmaniasis Severe folate or vitamin B12 deficiency
Pancytopenia
American artistic gymnast
Babcock died of complications from a bone marrow transplant to fight myelodysplastic syndrome at his home in Webster, Texas. Hutton, Mike (May 17, 1986). "Babcock
Brian_Babcock
leukemia, non-Hodgkin's lymphoma, myeloproliferative disorders, myelodysplastic syndrome) Engulfment of inflammatory cells by histiocytes, which is a hallmark
Emperipolesis
Class of immunomodulatory drugs
brain malignancies, AIDS-associated wasting syndrome, Crohn's disease, Kaposi's sarcoma, myelodysplastic syndrome, and hematopoietic stem cell transplantation
Cereblon_E3_ligase_modulator
Canadian-born American actor (1931–2014)
Florida, where he was receiving hospice care, from complications of myelodysplastic syndrome. He was 82. Madden, Dave (2007). Reuben on Wry: The Memoirs of
Dave_Madden
thymidine kinase activity in myelomas. A very interesting case is the myelodysplastic syndrome: some rapidly change to acute leukemia, whereas others remain indolent
Thymidine kinase in clinical chemistry
Thymidine_kinase_in_clinical_chemistry
Red, scaly rash of the cheeks and bridge of the nose
Alibraheem A, Wafa A, Alachkar W, et al. (December 2018). "Bloom syndrome with myelodysplastic syndrome that was converted into acute myeloid leukaemia, with new
Malar_rash
American novelist (1951–2019)
Georgia, in 1972. She died in Manhattan of complications from myelodysplastic syndrome on September 2, 2019, at the age of 67. Frank's writing career
Dorothea_Benton_Frank
American cinematographer
Peterman died at his home in Palos Verdes Estates, California, of myelodysplastic syndrome on February 5, 2011, at the age of 79. Film Television Documentary
Donald_Peterman
Canadian comedian (1959–2021)
early 2020, Macdonald was diagnosed with treatment-associated myelodysplastic syndrome, a cancer that later developed into acute myeloid leukemia. Macdonald's
Norm_Macdonald
American radio personality (1933–1995)
that McCarthy had a lack of platelets, and he was diagnosed with myelodysplastic syndrome, a condition that frequently develops into leukemia. McCarthy continued
J._P._McCarthy
Human gene
are frequently observed in myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), MDS/MPN overlap syndromes including chronic myelomonocytic
Tet methylcytosine dioxygenase 2
Tet_methylcytosine_dioxygenase_2
Human chromosome
Homocystinuria 3-Methylcrotonyl-CoA carboxylase deficiency Myelodysplastic syndrome Netherton syndrome Nicotine dependency Parkinson's disease Primary carnitine
Chromosome_5
Medical condition
an acute retroviral syndrome can present with fevers, rash and mono-like symptoms. Immune reconstitution inflammatory syndrome is a common cause of FUO
Fever_of_unknown_origin
Medical condition
Refractory cytopenia with multilineage dysplasia is a form of myelodysplastic syndrome. It is abbreviated "RCMD". Rosati S, Mick R, Xu F, et al. (January
Refractory cytopenia with multilineage dysplasia
Refractory_cytopenia_with_multilineage_dysplasia
Chemical compound
efficacy of prexasertib in treatment of acute myeloid leukemia, myelodysplastic syndrome, rhabdomyosarcoma, and medulloblastoma. Al Idrus A (30 April 2019)
Prexasertib
American actor (1934–2019)
of Brentwood for several years. Coe died on July 16, 2019, from myelodysplastic syndrome at the age of 84 in Palm Desert, California. Barry Coe (I) Archived
Barry_Coe
Acetylcholine receptors named for their selective binding of muscarine
cell differentiation. Therapies targeting the M4 receptor treats myelodysplastic syndrome and anemia that are refractory to erythropoietin. M4 receptors
Muscarinic acetylcholine receptor
Muscarinic_acetylcholine_receptor
American internet celebrity
in the next six years. During that time she was diagnosed with myelodysplastic syndrome (previously known as preleukemia) and progressive neuroblastoma;
Talia_Castellano
American jazz saxophonist and composer (1949–2007)
2007 from complications of leukemia following a 2005 diagnosis of myelodysplastic syndrome. Brecker was born to a Jewish family in Philadelphia, on March
Michael_Brecker
Lebanese-American health care fraudster (born 1965)
her hair after being falsely told she was terminally ill with myelodysplastic syndrome, and the stress of finding out about Fata's deceit gave her high
Farid_Fata
MYELODYSPLASTIC SYNDROME
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MYELODYSPLASTIC SYNDROME