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Medical condition
Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two
Multidrug-resistant tuberculosis
Multidrug-resistant_tuberculosis
Disease treatment
disease that is resistant to first line therapy (i.e., for extensively drug-resistant tuberculosis (XDR-TB) or multidrug-resistant tuberculosis (MDR-TB)).
Management_of_tuberculosis
Bacterium that causes tuberculosis
antibiotic or a change in titration of the drug. M. tuberculosis is considered to be multidrug-resistant (MDR TB) if it has developed drug resistance to both
Mycobacterium_tuberculosis
Infectious disease
growing phenomenon, which led to a higher incidence of multidrug-resistant tuberculosis. Tuberculosis has existed since antiquity. Skeletal remains show some
Tuberculosis
Tuberculosis that is resistant to the most effective drugs
Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB
Extensively drug-resistant tuberculosis
Extensively_drug-resistant_tuberculosis
Tuberculosis of the spine
symptoms of the disease. Cases of tuberculosis have been on the decline; however, infections of multidrug resistant tuberculosis have remained constant since
Pott's_disease
Bacteria resistant to three or more classes of antimicrobial drugs
Multidrug-resistant (MDR) bacteria are bacteria that are resistant to three or more classes of antimicrobial drugs, making them hard to treat. MDR bacteria
Multidrug-resistant_bacteria
State of tuberculosis infection without symptoms
2020-02-04. Retrieved 2012-09-25. "CDC | TB | Fact Sheets | Multidrug-Resistant Tuberculosis (MDR TB)". Cdc.gov. Archived from the original on 2015-10-03
Latent_tuberculosis
Medication used to treat tuberculosis
for use in tuberculosis (TB) treatment, as part of a fast-track accelerated approval, for use only in cases of multidrug-resistant tuberculosis, and the
Bedaquiline
patients with multidrug-resistant strains (resistant to, at least, both rifampin and isoniazid). In response to the resurgence of tuberculosis, the World
History_of_tuberculosis
Measure of microorganism drug resistance
in 2011. Common multidrug-resistant organisms, typically bacteria, include: Vancomycin-Resistant Enterococci (VRE) Methicillin-resistant Staphylococcus
Multiple_drug_resistance
Long term complication of tuberculosis
multi-drug-resistant tuberculosis. Around 10 percent have lost more than half of their lung function. Delayed diagnosis of TB, multidrug-resistant tuberculosis,
Post-tuberculosis lung disease
Post-tuberculosis_lung_disease
Tuberculosis that is resistant to more drugs than XDR-TB
Extensively drug-resistant tuberculosis (XDR-TB) Multidrug-resistant tuberculosis (MDR-TB) "WHO | Drug-resistant TB: Totally drug-resistant TB FAQ". WHO.
Totally drug-resistant tuberculosis
Totally_drug-resistant_tuberculosis
Global health initiative
worldwide, making it the highest burden country for both tuberculosis and multidrug-resistant tuberculosis. Matteelli, Alberto; Rendon, Adrian; Tiberi, Simon;
Elimination_of_tuberculosis
Chemical compound
to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active multidrug-resistant tuberculosis. It is taken
Delamanid
Vaccines to prevent tuberculosis
Stefan H. E.; van der Werf, Tjip S. (2013-04-01). "Targeting multidrug-resistant tuberculosis (MDR-TB) by therapeutic vaccines". Medical Microbiology and
Tuberculosis_vaccines
2025 nonfiction book by John Green
Cepheid to ease access to the tuberculosis treatment bedaquiline and rapid diagnostic testing for multidrug-resistant tuberculosis, respectively, which both
Everything_Is_Tuberculosis
American physician (born 1959)
Paul E, Kim JY. Community-based approaches to the control of multidrug-resistant tuberculosis: Introducing "DOTS-plus". British Medical Journal 1998; 317:671-4
Jim_Yong_Kim
Antibiotic medication
urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used by injection into a vein using an IV or into a
Amikacin
International health scare
tuberculosis scare occurred when a personal-injury lawyer from Atlanta, Andrew "Drew" Speaker, while infected with multidrug-resistant tuberculosis (MDR-TB)
2007_tuberculosis_scare
strains resistant to fluoroquinolone antibiotics, such as ciprofloxacin and levofloxacin, were also reported in North America in 2005. Multidrug-resistant Enterococcus
List of antibiotic-resistant bacteria
List_of_antibiotic-resistant_bacteria
Non-profit health care organization
influenced national policies for prevention and treatment of multidrug-resistant tuberculosis and HIV and provides important training and support to help
Partners_In_Health
Resistance of microbes to drugs directed against them
genetic mutations and the spread of resistant genes. Microbes resistant to multiple drugs are termed multidrug-resistant (MDR) and are sometimes called superbugs
Antimicrobial_resistance
Tuberculosis medication
primarily for the treatment of multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains of M. tuberculosis, remaining a second- or third-line
Cycloserine
Antibiotic medication
Brubakk O (February 2006). "Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)--a report of ten cases". The Journal of Infection
Linezolid
Invasion of an organism's body by pathogenic agents
7326/0003-4819-127-8_Part_1-199710150-00010. PMID 9341063. S2CID 20357515. Multidrug-Resistant "Tuberculosis". Centers for Disease Control and Prevention. Archived March
Infection
U.S.-based nonprofit organization
humanitarian assistance to rural North Korea. Focusing on multidrug-resistant tuberculosis, the foundation currently sponsors 12 treatment centers, drawing
Eugene_Bell_Foundation
Antimicrobial substance active against bacteria
challenges. Every year, nearly half a million new cases of multidrug-resistant tuberculosis (MDR-TB) are estimated to occur worldwide. For example, NDM-1
Antibiotic
Chemical compound
to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, to treat active multidrug-resistant tuberculosis. It is no
Ethionamide
Belgian scientist
ATP-synthase of Mycobacterium tuberculosis, Science 307 (5707): 223–27 Invention: Drug against multidrug-resistant tuberculosis Koen Andries (University of
Koen_Andries
Antibiotic to treat bacterial infections
Other uses, along with other medications, include treating multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection
Ofloxacin
of bacteria. Antibiotic-resistant TB is also known as "multidrug-resistant tuberculosis." "Multidrug-resistant tuberculosis" is a pandemic that is on
Globalization_and_disease
estimated total of new cases, and multidrug-resistant tuberculosis was a major problem. These signs of inadequate tuberculosis control can be linked to a malfunctioning
Tuberculosis_in_China
Combination of two antibiotic drugs
(August 2013). "Evaluation of co-trimoxazole in the treatment of multidrug-resistant tuberculosis". The European Respiratory Journal. 42 (2): 504–512. doi:10
Trimethoprim/sulfamethoxazole
Anti-tuberculosis and anti-inflammatory drug
streptomycin) for treating tuberculosis and its cost is higher, but it is still useful in the treatment of multidrug-resistant tuberculosis. PAS is always used
4-Aminosalicylic_acid
Peruvian biologist
development and enhancement of diagnostic methods for tuberculosis and multidrug-resistant tuberculosis. In 2014, she was awarded the National L'Oréal-Unesco-Concytec
Patricia_Sheen
American doctor and CEO
malaria and HIV/AIDS in Tanzania and he did his thesis on multidrug resistant tuberculosis in Peru. Narasimhan joined McKinsey & Co, as a consultant and
Vasant_Narasimhan
Antibiotic
is very concerning for its use in treating multidrug-resistant tuberculosis and other multidrug-resistant Gram-negative bacterial infections. This is
Kanamycin_A
British microbiologist
of tuberculosis (TB) and other respiratory infections, including multidrug-resistant forms and their implications for treatment and public health. He
Francis_Drobniewski
Indian pulmonologist
pulmonologist and researcher. His work on drug resistant tuberculosis has led to improvements in India's National Tuberculosis Control Programme. Udwadia was the
Zarir_Udwadia
Particulate respirator meeting the N95 standard
along with chemical cartridge requirements. In 1992, the multidrug-resistant tuberculosis task force within the CDC was tasked with reducing the incidences
N95_respirator
Medication
with multidrug-resistant tuberculosis. M. bovis is innately resistant due to a H57D difference in pncA (when compared to the version of M. tuberculosis).
Pyrazinamide
American microbiologist
microbiologist whose research focuses on Mycoplasma species and multidrug-resistant tuberculosis. She is vice president of TB drug development at the Infectious
Gail_H._Cassell
Medical condition
levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance
Pneumococcal_infection
Widespread, often global, epidemic of severe infectious disease
professionals. Every year, nearly half a million new cases of multidrug-resistant tuberculosis (MDR-TB) are estimated to occur worldwide. China and India
Pandemic
Inflammation of membranes around the brain
in tuberculosis meningitis. HIV co-infection, multidrug resistant tuberculosis, or the development of hydrocephalus or focal weakness in tuberculosis meningitis
Chronic_meningitis
Private foundation founded by Bill and Melinda Gates
strain is resistant to the bactericidal antibiotic rifampicin, a widely accepted indicator of the presence of multidrug resistant tuberculosis. Visceral
Gates_Foundation
Chemical compound
treatment of pulmonary extensively drug resistant, or treatment-intolerant or nonresponsive multidrug-resistant tuberculosis. Pretomanid is activated in the mycobacterium
Pretomanid
Cengage Learning. ISBN 978-1-133-31272-7. OCLC 890080129. "Multidrug-Resistant Tuberculosis". Centers for Disease Control and Prevention. Archived from
Timeline_of_the_19th_century
Professor of Computational Biology at UCL
"Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis". eLife. 5 e16644. doi:10.7554/eLife.16644. ISSN 2050-084X
François_Balloux
New or rapidly increasing disease
bioterrorism potential, CDC category C (least dangerous): Influenza Multidrug-resistant tuberculosis (MDR-TB) Nipah virus Rabies SARS coronavirus Tick-borne encephalitis
Emerging_infectious_disease
Medical diagnostic method
recovering from, tuberculosis.[citation needed] Brust, J. (6 Jan 2011). "Culture Conversion Among HIV Co-Infected Multidrug-Resistant Tuberculosis Patients in
Culture_conversion
One hundred years, from 1801 to 1900
Archived from the original on 2010-01-04. Retrieved 2008-03-03. "Multidrug-Resistant Tuberculosis". Centers for Disease Control and Prevention. 2018-12-31. Archived
19th_century
Tuberculosis disgnostic and antibiotic sensitivity test
rapid tuberculosis diagnosis and rapid antibiotic sensitivity test. It is an automated diagnostic test that can identify Mycobacterium tuberculosis (MTB)
GeneXpert_MTB/RIF
Antibiotic medication
first-line antitubercular drugs. Early detection of such multidrug or extensively drug-resistant tuberculosis is critical in improving patient outcomes by instituting
Rifampicin
Formulary by the World Health Organization
Terizidone is an alternative Prothionamide is an alternative for multidrug-resistant tuberculosis Imipenem/cilastatin is an alternative For treatment of chronic
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
and tuberculosis 50.5 6.85% −24.5 Tuberculosis 14.9 2.02% −31.4 Drug-susceptible tuberculosis 13.2 1.79% −31.9 Multidrug-resistant tuberculosis without
List of causes of death by rate
List_of_causes_of_death_by_rate
Use of antibiotics for any purpose in the husbandry of livestock
people die each year from drug-resistant infections, including approximately 230,000 deaths from multidrug-resistant tuberculosis. In addition to the health
Antibiotic_use_in_livestock
Species of bacterium
M. tuberculosis isolates, suggesting that it may be a useful starting point in developing new antibiotics to treat multidrug resistant tuberculosis infections
Burkholderia_gladioli
Bacteriology medium
Automated BACTEC MGIT 960 System for Testing Susceptibility of Mycobacterium tuberculosis to Four Major Antituberculous Drugs: Comparison with the Radiometric
Mycobacteria growth indicator tube
Mycobacteria_growth_indicator_tube
American physician
by nearly half and cutting multidrug-resistant tuberculosis by 80 percent. The city's program became a model for tuberculosis control nationally and globally
Tom_Frieden
2003 book by Tracy Kidder
continued to work for PIH. PART III: Médicos Aventureros In 1995, multidrug-resistant tuberculosis (MDR TB) claimed the life of a close friend known as Father
Mountains_Beyond_Mountains
Complementary Approach to Treat Cavities in Multidrug-Resistant Tuberculosis and Difficult-to-Treat Tuberculosis: A Case Series". Respiration. 92 (5): 316–328
Endobronchial_valve
estimated total of new cases, and multidrug-resistant tuberculosis was a major problem. These signs of inadequate tuberculosis control can be linked to a malfunctioning
Health_in_China
Peruvian physician
Partners in Health (PIH) that started in Lima, Peru, to treat multidrug-resistant tuberculosis (MDR-TB) and HIV/AIDS in patients, and to provide health care
Jaime_Bayona
Hospital in Pune, Maharashtra, India
offers practical recommendations to enhance tuberculosis care (TB) and multidrug-resistant tuberculosis (MDR-TB). A Bachelor of Medicine and Bachelor
Dr. D. Y. Patil Medical College, Hospital & Research Centre
Dr._D._Y._Patil_Medical_College,_Hospital_&_Research_Centre
is to detect and cure TB, as well as to prevent and treat multidrug-resistant tuberculosis (MDR-TB) in India and Cambodia. Operation ASHA specializes
Operation_ASHA
Hospital in Maseru, Lesotho
with Multidrug-resistant tuberculosis exclusively. As of 2020, it was the only hospital in the country accredited to provide comprehensive tuberculosis drug
Botšabelo_Hospital
U.S. Centers for Disease Control and Prevention program
Belongia, C.W. Hedberg, G.J. Gleich, et al. 1992 An Outbreak of Multidrug-Resistant Tuberculosis Among Hospitalized Patients with the Acquired Immunodeficiency
Epidemic_Intelligence_Service
Pathogen resistance to medications
and drive research. When an organism is resistant to more than one drug, it is said to be multidrug-resistant. The development of antibiotic resistance
Drug_resistance
Medical non-profit for tuberculosis
societies. The cost of treating a single case of multidrug-resistant TB (MDR-TB) or extensively drug-resistant TB (XDR-TB) can be thousands of times more expensive
TB_Alliance
High Incidence of Hospital Admissions with Multidrug Resistant and Extensively Drug Resistant Tuberculosis among South African Health Care Workers. Ann
Keertan_Dheda
Prison system in Russia
Barriers to successful tuberculosis treatment in Tomsk, Russian Federation: non-adherence, default and the acquisition of multidrug resistance. Bulletin
Prisons_in_Russia
Provincial capital and city in Kasai-Oriental, Democratic Republic of the Congo
Bouke C.; Boelaert, Marleen (2018). "Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of
Mbuji-Mayi
Amino acid
function, immunological response and gut flora. With multidrug-resistant Mycobacterium tuberculosis (TB) remaining a public health crisis with a total of
Threonine
Long fatty acids found in the cell walls of the Mycobacteriales taxon
; Geiter, L. J.; Wells, C. D. (2012). "Delamanid for Multidrug-Resistant Pulmonary Tuberculosis". New England Journal of Medicine. 366 (23): 2151–2160
Mycolic_acid
Chemical compound
Ruesch-Gerdes, Sabine; Lange, Christoph (November 2008). "Multidrug- and Extensively Drug-Resistant Tuberculosis, Germany". Emerging Infectious Diseases. 14 (11):
Gladiolin
Infection-control precautions in health care
application of contact precautions for patients infected or colonized with Multidrug-Resistant Organisms MDROs is described in the 2006 HICPAC/CDC MDRO guideline
Transmission-based precautions
Transmission-based_precautions
drug‑sensitive TB. Despite this progress, multidrug‑resistant tuberculosis (MDR‑TB) and extensively drug‑resistant tuberculosis (XDR‑TB) are of major concern, with
Health_in_Namibia
Castro, Kenneth G.; Weyer, Karin (2007). "HIV Infection and Multidrug-Resistant Tuberculosis: The Perfect Storm". The Journal of Infectious Diseases. 196:
HIV/AIDS_in_Lesotho
Formulary
combination with meropenem Prothionamide is an alternative for multidrug-resistant tuberculosis Imipenem/cilastatin is an alternative For treatment of chronic
WHO Model List of Essential Medicines for Children
WHO_Model_List_of_Essential_Medicines_for_Children
Species of bacterium
Infections due to multidrug-resistant gram-negative pathogens in the ICU have invoked the re-emergence of colistin. However, colistin-resistant strains of K
Klebsiella_pneumoniae
Protein family
"Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics"
Peptidoglycan recognition protein
Peptidoglycan_recognition_protein
American epidemiologist
develop a mathematical model that proved that a number of multidrug-resistant strains of tuberculosis can easily reproduce and spread. She also worked with
Megan_B._Murray
Inflammation of the alveoli of the lungs
with healthcare-associated pneumonia, it is less likely to involve multidrug-resistant bacteria. Although the latter are no longer rare in CAP, they are
Pneumonia
Class of highly effective antibiotic agents
class of antibiotics is usually reserved for known or suspected multidrug-resistant (MDR) bacterial infections. Similar to penicillins and cephalosporins
Carbapenem
Disease caused by the bacteria Salmonella typhi
first-line treatment of typhoid fever. Typhoid resistant to these agents is known as multidrug-resistant typhoid. Ciprofloxacin resistance is an increasing
Typhoid_fever
for the Treatment of Multidrug-Resistant Tuberculosis in 134 Low- and Middle-Income Countries". JnJ. 29 September 2023. "Tuberculosis Advocates Push For
Access_to_medicines
Chemical compound
"Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections". Antimicrobial Agents and Chemotherapy
Tebipenem_pivoxil
role of surgery in the treatment of pulmonary TB and multidrug- and extensively drug-resistant TB. WHO: Geneva 2014. p.8 Collaborating Centre WHO-NTRI
Novosibirsk TB Research Institute
Novosibirsk_TB_Research_Institute
Epidemiology method
"Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis". eLife. 5. doi:10.7554/eLife.16644. PMC 4978521. PMID 27502557
Source_attribution
services. March 28 – In a report presented by DOH, cases of multidrug resistant Tuberculosis (MDR-TB) increased to 10,000 cases in Northern Mindanao. April
2014_in_the_Philippines
Tuberculosis vaccine candidate
(January 2001). "High rate of tuberculosis reinfection during a nosocomial outbreak of multidrug-resistant tuberculosis caused by Mycobacterium bovis
MTBVAC
Infection spread in hospitals or health care facilities
staff to adequately control the spread of infections. Moreover, multidrug-resistant infections can leave the hospital and become part of the community
Hospital-acquired_infection
Gambian clinician
"Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria". PLOS ONE. 12 (9) e0184510. Bibcode:2017PLoSO
Tumani_Corrah
Newborn Health 2009: The Global Nutrition Challenge 2008: Multidrug-resistant Tuberculosis 2007: Pandemics 2006: Early Health 2005: Science, Innovation
Pacific_Health_Summit
well as a high rate of tuberculosis, which is present on all the islands. Twenty-one cases of multidrug-resistant tuberculosis were detected in Chuuk
Health in the Federated States of Micronesia
Health_in_the_Federated_States_of_Micronesia
Bacterium that causes leprosy
1960s, it has developed resistance against this antibiotic. Currently, a multidrug treatment (MDT) is recommended by the World Health Organization, including
Mycobacterium_leprae
American epidemiologist
Wells (2005). "Clinical outcome of individualised treatment of multidrug-resistant tuberculosis in Latvia: a retrospective cohort study". The Lancet. 365 (9456):
Lorna_Thorpe
American public health doctor
Health Organization Green Light Committee on the Treatment of Multidrug Resistant Tuberculosis, the Infectious Disease Society of America Committee on International
Joia_Mukherjee
travel, tourism, insurance
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
MULTIDRUG RESISTANT-TUBERCULOSIS
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