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Mitochondrial gene coding for a protein involved in the respiratory chain
MT-ND4 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 4 (ND4) protein. The ND4 protein is a subunit of NADH
MT-ND4
Topics referred to by the same term
ND4 can mean several things: Neutral density filter (ND) with an attenuation factor of 4, or simply ND4 MT-ND4, NADH dehydrogenase subunit 4, or simply
ND4
DNA located in mitochondria
Mitochondrial DNA (mDNA or mtDNA) is the DNA located in the mitochondria organelles in a eukaryotic cell which encodes genes to convert chemical energy
Mitochondrial_DNA
Mitochondrial gene coding for a protein involved in the respiratory chain
enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, and MT-ND6. Also known as Complex I, this enzyme is the largest
MT-ND4L
Mitochondrial protein-coding gene whose product is involved in ATP synthesis
known to cause mtDNA-associated Leigh syndrome involve MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6 and MT-CO3. Abnormalities
MT-ATP6
Mitochondrial gene coding for a protein involved in the respiratory chain
gene MT-ND1 are known to cause mtDNA-associated Leigh syndrome, as are variants of MT-ATP6, MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND2, MT-ND3, MT-ND4, MT-ND5
MT-ND1
Mitochondrial gene coding for a protein involved in the respiratory chain
gene MT-ND2 are known to cause mtDNA-associated Leigh syndrome, as are variants of MT-ATP6, MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND3, MT-ND4, MT-ND5
MT-ND2
Inhalational anaesthetic
even death in otherwise healthy persons, especially children, with the MT-ND4 11232T>C genetic anomaly. This anomaly originated in Venezuela and is at
Sevoflurane
Mitochondrial protein-coding gene whose product is involved in the respiratory chain
gene MT-ND3 are known to cause mtDNA-associated Leigh syndrome, as are variants of MT-ATP6, MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND2, MT-ND4, MT-ND5
MT-ND3
Mitochondrial gene coding for a protein involved in the respiratory chain
enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, and MT-ND6. Also known as Complex I, this enzyme is the largest
MT-ND5
Study of the human mitochondrial genome
are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular
Human_mitochondrial_genetics
Protein complex involved in cellular respiration
subunit 3 MT-ND4 - mitochondrially encoded NADH dehydrogenase subunit 4 MT-ND4L - mitochondrially encoded NADH dehydrogenase subunit 4L MT-ND5 - mitochondrially
Respiratory_complex_I
Mitochondrial gene coding for a protein involved in the respiratory chain
dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, and MT-ND5. Also known as Complex I, this enzyme is the largest of the respiratory
MT-ND6
Mitochondrially inherited degeneration of retinal nerve cells
mitochondrial DNA (mtDNA) point mutations. These mutations are at nucleotide positions 11778 G to A, 3460 G to A and 14484 T to C, respectively in the ND4, ND1 and
Leber's hereditary optic neuropathy
Leber's_hereditary_optic_neuropathy
Group of visual disorders
common mtDNA point mutations (m.3460G>A/MT-ND1, m.11778G>A/MT-ND4, m.14484T>C/MT-ND6) while a wider range of mtDNA mutations (MT-ND1, MT-ND5, MT-ND6; WebHome
Mitochondrial optic neuropathies
Mitochondrial_optic_neuropathies
French ophthalmologist and scientist
(2023-04-03). "Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy". Brain. 146 (4): 1328–1341. doi:10.1093/brain/awac421
José-Alain_Sahel
Type of gene expression
Gensight Biologics began a clinical program of allotopic expressing the MT-ND4 gene in the nucleus as therapies for Leber's hereditary optic neuropathy
Allotopic_expression
P00414 9946 MT-CYB HGNC:7427; P00156 9947 MT-ND1 HGNC:7455; P03886 9948 MT-ND2 HGNC:7456; P03891 9949 MT-ND3 HGNC:7458; P03897 9950 MT-ND4 HGNC:7459; P03905
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Species of bird
"Phylogenetics of the common raven complex (Corvus: Corvidae) and the utility of ND4, COI and intron 7 of the β-fibrinogen gene in avian molecular systematics"
Chihuahuan_raven
Sporadic biological phenomenon at the molecular scale
sequences of the mitochondrial cytochrome oxidase I, ND4 , ND4L , and 12S rRNA genes. Based on these findings, mtDNA fragments were assumed to act as a mobile
Nuclear mitochondrial DNA segment
Nuclear_mitochondrial_DNA_segment
Large, black species of passerine bird
"Phylogenetics of the common raven complex (Corvus: Corvidae) and the utility of ND4, COI and intron 7 of the β-fibrinogen gene in avian molecular systematics"
Common_raven
Protein-coding gene in the species Homo sapiens
"Structural organization of mitochondrial human complex I: role of the ND4 and ND5 mitochondria-encoded subunits and interaction with prohibitin". The
NDUFS3
Protein found in humans
"Structural organization of mitochondrial human complex I: role of the ND4 and ND5 mitochondria-encoded subunits and interaction with prohibitin". The
NDUFS2
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MT ND4
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