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Class of chemical compounds
Lysergamides, also known as ergoamides or as lysergic acid amides, are amides of lysergic acid (LA). They are ergolines, with some lysergamides being
Lysergamides
Psychedelic drug
(d-iso-LSD), l-LSD, and l-iso-LSD. The 5S- or levo- stereoisomers of lysergamides do not exist in nature and are not formed during the synthesis from d-lysergic
LSD
Class of chemical compounds
simplified ergolines and lysergamides, also known as deconstructed LSD analogues, are analogues of ergolines and lysergamides like the psychedelic drug
Partial_lysergamide
Chemical manufacturer and vendor, 2012–2024
psychedelic lysergamides in the 2010s and 2020s, for instance the "Return of the Lysergamides" series of papers on lysergamides and lysergamide prodrugs
Lizard_Labs
structural families, including the tryptamines, phenethylamines, and lysergamides, although exceptions exist. N-(2-Cyanoethyl)tryptamine (CE-T) Deudimethyltryptamine
List_of_psychedelic_drugs
Pharmaceutical compound
similar to simplified/partial lysergamides and has elements of the chemical structure of LSD and related psychedelic lysergamides like LSD-Pip within its structure
25B-NAcPip
Precursor for a range of ergoline alkaloids produced by the ergot fungus
(morning glories, ololiuhqui, tlitliltzin). Amides of lysergic acid, lysergamides, are widely used as pharmaceuticals and as psychedelic drugs, e.g. lysergic
Lysergic_acid
Genus of flowering plants
Periglandula fungi. Seeds of I. tricolour and I. purpurea commonly contain lysergamides such as ergine (D- lysergic acid amide, LSA) and its epimer isoergine;
Ipomoea
Pharmaceutical compound
6-methyl-LEK-8842 or as 6-methyl-N-methyl-N-(2-propynyl)lysergamide, is a chemical compound of the lysergamide family. It is the 6-methyl derivative of LEK-8842
LEK-8827
implicitly banned under catch-all clauses. Conversely, most tryptamines, lysergamides, and scalines are not explicitly nor implicitly banned in Canada as of
Legal status of psychedelic drugs in Canada
Legal_status_of_psychedelic_drugs_in_Canada
Hallucinogenic class of psychoactive drug
ergolines and lysergamides may be considered structurally related to the monoamine neurotransmitters. Many ergolines and lysergamides act as highly promiscuous
Psychedelic_drug
Chemical compound
and is the parent structure of this family of compounds. Hence, all lysergamides are derivatives of ergine. Lysergic acid diethylamide (LSD) is the analogue
Ergine
Pharmaceutical compound
6-methyl-9-ergolene, is a drug of the ergoline and partial lysergamide families related to lysergic acid and lysergamides like lysergic acid diethylamide (LSD). It is
Descarboxylysergic_acid
Psychedelic drug
include other lysergamides like the 6-substituted lysergamides ETH-LAD, PRO-LAD, AL-LAD, and CE-LAD; the amide-substituted lysergamides LA-3Cl-SB, EcPLA
LSZ
Chemical compound
moiety; the chemical backbone of the lysergamide and ergoline molecules. However, as with other N-acylated lysergamides, 1V-LSD reacts very slowly to Ehrlich
1V-LSD
Pharmaceutical compound
analogues. Substituted lysergamide CE-LAD Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited" (PDF). NIDA Research
LA-Aziridine
Chemical compound (psychedelic drug)
It is closely structurally related to LSD and to other psychedelic lysergamides such as ETH-LAD and PRO-LAD. AL-LAD was first described in the scientific
AL-LAD
Pharmaceutical compound
It has oxytocic effects on the isolated rat uterus similarly to other lysergamides, shows antiserotonergic effects in the isolated rat intestine similarly
Lysergic_acid_cyclobutylamide
Chemical compound
Stratford A, Odland AU, Klein AK, et al. (June 2020). "Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic
1cP-LSD
Pharmaceutical compound
by 1994. Substituted lysergamide NBOMe-LAD Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited". NIDA Research
PHENETH-LAD
Chemical compound
experiential fingerprints of substituted phenethylamines, tryptamines and lysergamides". Psychopharmacology (Berl). 239 (6): 1783–1796. doi:10.1007/s00213-022-06142-4
1P-LSD
Chemical class of organic compounds
benzoctamine and dizocilpine Ergolines and lysergamides like ergine (LSA) and LSD Partial ergolines and lysergamides like NDTDI, RU-27849, UCD0179, and UCD0120
Substituted_phenethylamine
Pharmaceutical compound
drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the 1-acetyl derivative of LAE-32. 1-Acetylated lysergamides like ALD-52
ALA-10
Species of fungus
occurring lysergamides or ergot alkaloids like ergine (lysergic acid amide; LSA) and isoergine (isolysergic acid amide; iso-LSA). The lysergamides present
Periglandula_clandestina
Family of neurotransmitters
compounds that contain an amino group. Examples of indolamines include the lysergamides. [citation needed] Indolamines are biologically synthesized from the
Indolamines
Pharmaceutical compound
6-cyclopropyl-6-nor-lysergic acid diethylamide or as TRALA-22, is a lysergamide and analogue of lysergic acid diethylamide (LSD). It was patented by
CYP-LAD
Pharmaceutical compound
as of 2025. Substituted lysergamide CYP-LAD Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited" (PDF). NIDA
CPM-LAD
Chemical compound, Novel psychoactive substance analog, LSD prodrug
typically distributed in its hemi-D-tartrate form, a common format for lysergamides due to its stability and ease of use. The dose of 1S-LSD is reported
1S-LSD
Chemical compound
Stratford A, Elliott SP, Hoang K, et al. (September 2016). "Return of the lysergamides. Part I: Analytical and behavioural characterization of 1-propionyl-d-lysergic
ALD-52
Pharmaceutical compound
and methysergide (UML-491). Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide
Propisergide
Pharmaceutical compound
of 1-methyl-LSD (MLD-41). Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide
MPD-75
25B-NMe7Indz 25B-NMePyr 25I-NMe7DHBF 25I-NMeFur 25I-NMeTHF 25I-NMeTh Lysergamides are amide derivatives of the alkaloid lysergic acid. 1B-LSD, 1-Butanoyl-LSD
List_of_designer_drugs
Pharmaceutical compound
acid ethylamide (LAE-32). Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide
MLA-74
Chemical compound
6-propynyl-6-nor-LSD or 6-propargyl-6-nor-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). PARGY-LAD is hallucinogenic
PARGY-LAD
Pharmaceutical compound
1-Dimethylaminomethyl-LSD is a lysergamide derivative related to the psychedelic drug lysergic acid diethylamide (LSD). It was synthesized and described
1-Dimethylaminomethyl-LSD
Chemical compound
It is closely structurally related to LSD and to other psychedelic lysergamides like PRO-LAD and AL-LAD. ETH-LAD was first described in the scientific
ETH-LAD
Pharmaceutical compound
ethyl-2-methoxyethylamide or as N-ethyl-N-(2-methoxyethyl)lysergamide, is a serotonin receptor modulator of the lysergamide family related to lysergic acid diethylamide
LA-MeO
Pharmaceutical compound
2,3-dihydrolysergic acid diethylamide, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the analogue
2,3-Dihydro-LSD
Compound related to LSD
between these two lysergamides. At the same time, it is worth noting that in addition to ECPLA and LSZ, several other isomeric lysergamides have been described
LA-Pip
Pharmaceutical compound
10,11-Seco-LSD, also known as UCD0121, is a partial lysergamide and cyclized tryptamine related to lysergic acid diethylamide (LSD). It is the seco analogue
10,11-Seco-LSD
clause for lysergamides in the Misuse of Drugs Act 1971 aside from N-alkylated derivatives as of 2022, although various individual lysergamides are banned
Legal status of psychedelic drugs in the United Kingdom
Legal_status_of_psychedelic_drugs_in_the_United_Kingdom
Pharmaceutical compound
5-HT2C, and 5-HT1A receptor affinity and functional effects for selected lysergamides [...] Nichols DE (2012). "Structure–activity relationships of serotonin
LA-Azepane
Psychedelic drug
ibogaine and noribogaine; lysergamides like ergine (LSA) and lysergic acid diethylamide (LSD); and partial ergolines and lysergamides like N-DEAOP-NMT, 10
Dimethyltryptamine
Pharmaceutical compound
Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited". NIDA Research Monograph. 146: 52–73. PMID 8742794. The other
Ethylpropyllysergamide
Pharmaceutical compound
dihydropyrrol lysergamide or as N-(2,5-dihydro-1H-pyrrolyl)lysergamide, is a serotonin receptor modulator and possible psychedelic drug of the lysergamide family
Lysergic_acid_pyrrolinide
Chemical compound
lysergamide family related to lysergic acid diethylamide (LSD). It is an isomer of LSZ and is closely related to other amide-substituted lysergamides
EcPLA
Pharmaceutical compound
N-(dihydrolysergyl)sphingosine, is a dopamine agonist of the ergoline and lysergamide families which was never marketed. It is similar in chemical structure
Dosergoside
Species of fungus
of the Claviceps species that has the capacity to produce psychedelic lysergamides such as ergine (lysergic acid amide; LSA) and isoergine. Claviceps paspali
Claviceps_paspali
Pharmaceutical compound
N-diethyllysergamide and sometimes referred to as 1F-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the 1-formyl
1-Formyl-LSD
Pharmaceutical compound
that it could have psychedelic effects in humans. Unlike other assessed lysergamides however, DIPLA was much less potent than LSD, about 8-fold so in the
DiPLA
Chemical compound
1531 (LY-197206), LY-293284, and LY-178210. Other partial/simplified lysergamides include UCD0179 (4-nor-LSD), UCD0120 (dides-B,C-LSD), and 10,11-seco-LSD
NDTDI
Brand of mushroom edibles
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Diamond_Shruumz
Pharmaceutical compound
Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited" (PDF). NIDA Research Monograph. 146: 52–73. PMID 8742794.
IPLA
Pharmaceutical compound
Lysergyl-L-valyl methyl ester is an ergot alkaloid and lysergamide found as a minor constituent in Claviceps purpurea (ergot). It is an analogue of ergovalide
Lysergyl-L-valyl_methyl_ester
psilocybin-containing mushrooms and ergine (LSA) from morning glory, developed numerous lysergamides and some psilocybin analogues Alexander Shulgin – developed numerous
List_of_psychedelic_chemists
Pharmaceutical compound
of 2-bromo-LSD (BOL-148). Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide
MBL-61
Pharmaceutical compound
quantifiable oxytocic effects in animals. However, in contrast to other lysergamides such as lysergic acid and ergonovine (ergometrine), N-DEAOP-NMT was said
N-DEAOP-NMT
Pharmaceutical compound
or as 9,10-dihydro-N-methyl-N-(2-propynyl)lysergamide, is a monoamine receptor modulator of the lysergamide family related to 9,10-dihydro-LSD. It is
LEK-8822
1997 book by Alexander Shulgin and Ann Shulgin
or harmala alkaloids like harmaline, the iboga alkaloid ibogaine, and lysergamides like LSD. Whereas PiHKAL had 179 entries on phenethylamines, TiHKAL has
TiHKAL
Pharmaceutical compound
known as N-(2-pentyl)lysergamide (N2Pe-LA), is a serotonin receptor modulator and possible psychedelic drug of the lysergamide family related to lysergic
Lysergic_acid_2-pentylamide
Central nervous system stimulant
Phenylbutylamines (e.g., 4-Phenylbutylamine, 4-Phenylpentan-1-amine) See also: Tryptamines Ergolines and lysergamides Stimulants Entactogens Psychedelics
Methamphetamine
Species of fungus
Phenethylamines (e.g., mescaline, 2C-B, DOM, MDA, TMA, 2C-B-FLY, 25I-NBOMe) Lysergamides (e.g., LSD, ergine, isoergine) Others (e.g., efavirenz, glaucine, IHCH-7113
Lanmaoa_asiatica
Pharmaceutical compound
1-(3-(tetramethyldioxaborolane)propionyl)-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is thought to
1BP-LSD
Chemical compound
lysergic acid (i.e., lysergamides); (2) the water-insoluble ergopeptines (i.e., ergopeptides); and (3) the clavine group. Only the lysergamides have been known
Ergoline
Pharmaceutical compound
Diversion Control Division, January 2026 1D-LSD - Isomer Design 1D-LSD - Bluelight From 1V-LSD to 1D-LSD: The Evolution of Legal Lysergamides - Sociedelic
1D-LSD
Chemical compound
"Separating the wheat from the chaff: Observations on the analysis of lysergamides LSD, MIPLA, and LAMPA". Drug Test Anal. 14 (3): 545–556. doi:10.1002/dta
MiPLA
Pharmaceutical compound
has a simplified lysergamide-like chemical structure, with a 1-aminotetralin ring system, and is structurally related to lysergamides like ergometrine
Tochergamine
Pharmaceutical compound
Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994). "Lysergamides revisited". NIDA Research Monograph. 146: 52–73. PMID 8742794. The stereochemistry
Isoergine
Common name for flowering plants in the family Convolvulaceae
contain ergoline alkaloids such as the psychoactive and/or psychedelic lysergamides ergine (lysergic acid amide; LSA) and isoergine (isolysergic acid amide;
Morning_glory
Pharmaceutical compound
2-oxy-LSD or 2-keto-LSD, or more fully as 2-oxo-2,3-dihydro-LSD, is a lysergamide and metabolite of the psychedelic drug lysergic acid diethylamide (LSD)
2-Oxo-LSD
Class of chemical compounds
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Scaline
Food containing hallucinogenic substances
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Mushroom_edible
Type of psychoactive fungus
Phenethylamines (e.g., mescaline, 2C-B, DOM, MDA, TMA, 2C-B-FLY, 25I-NBOMe) Lysergamides (e.g., LSD, ergine, isoergine) Others (e.g., efavirenz, glaucine, IHCH-7113
Hallucinogenic bolete mushroom
Hallucinogenic_bolete_mushroom
Pharmaceutical compound
14-Methoxy-LSD is a lysergamide related to lysergic acid diethylamide (LSD). It is the derivative of LSD with a methoxy group at the 14 position and is
14-Methoxy-LSD
Pharmaceutical compound
Other lumi-lysergamides are also known. Lumi-LSD was first described in the scientific literature by at least 1955. Substituted lysergamide 9,10-Dihydro-LSD
Lumi-LSD
Pharmaceutical compound
1-(ferrocenecarbonyl)-LSD or as SYN-L-234, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is thought to
1Fe-LSD
Drug class
serotonin, and include tryptamines, phenethylamines, and ergolines and lysergamides, among other chemical classes. In addition to the recreational and entheogenic
Serotonin 5-HT2A receptor agonist
Serotonin_5-HT2A_receptor_agonist
Medication used to treat anxiety disorders
McCorvy JD, Nichols DE, Halberstadt AL (February 2018). "Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic
Buspirone
Selective dopamine autoreceptor agonist
described as an antipsychotic, which was never marketed. Lysergamides § Simplified or partial lysergamides LY-178210 Bay R 1531 (LY-197206) LY-293284 William
Alentemol
Chemical compound
monoalkyl lysergamides foreshadowing the subsequent development of compounds such as lysergic acid 2,4-dimethylazetidide (LSZ). Substituted lysergamide Lysergic
Lysergic_acid_2-butylamide
Chemical compound
Stratford A, Elliott SP, Dowling G, et al. (August 2019). "Return of the lysergamides. Part V: Analytical and behavioural characterization of 1-butanoyl-d-lysergic
1B-LSD
Pharmaceutical compound
Phenylbutylamines (e.g., 4-Phenylbutylamine, 4-Phenylpentan-1-amine) See also: Tryptamines Ergolines and lysergamides Stimulants Entactogens Psychedelics
MFEM_(drug)
Pharmaceutical compound
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Alpha,Beta-D
Pharmaceutical compound
known as 1-benzoyl-LSD or as SYN-L-018, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is thought to
1Bz-LSD
Iboga alkaloids β-Carbolines Harmala alkaloids Ergolines Lysergamides Simplified/partial lysergamides Phenethylamines (methoxyphenethylamines) 2Cs 25-NB/NBOMes
Orphine
Medical condition
Phenethylamines (e.g., mescaline, 2C-B, DOM, MDA, TMA, 2C-B-FLY, 25I-NBOMe) Lysergamides (e.g., LSD, ergine, isoergine) Others (e.g., efavirenz, glaucine, IHCH-7113
Amaryllidaceae_alkaloid
Pharmaceutical compound
derivative of 2-iodo-LSD (IOL). Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide
1-Methyl-2-iodo-LSD
Pharmaceutical compound
Phenylbutylamines (e.g., 4-Phenylbutylamine, 4-Phenylpentan-1-amine) See also: Tryptamines Ergolines and lysergamides Stimulants Entactogens Psychedelics
Desoxybromoscaline
Chemical compound
Chanoclavine II Cycloclavine Paliclavine Lysergamides (lysergic acid amides) Non-hallucinogenic lysergamides: 1P-BOL-148 2-Bromo-LSD (bromolysergide;
10,11-Secoergoline
Pharmaceutical compound
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
2-DM-DOM
Central nervous system stimulant
Iboga alkaloids β-Carbolines Harmala alkaloids Ergolines Lysergamides Simplified/partial lysergamides Phenethylamines (methoxyphenethylamines) 2Cs 25-NB/NBOMes
Methylphenidate
Pharmaceutical compound
a putatively non-hallucinogenic serotonin receptor modulator of the lysergamide family related to 2-bromo-LSD (BOL-148) and lysergic acid diethylamide
2-Iodo-LSD
Pharmaceutical compound
Barettin BML-190 (indomethacin morpholinylamide) Cyclic 3-OHM Ergolines and lysergamides (e.g., LSD) Harmala alkaloids and β-carbolines (e.g., 5-methoxyharmalan
6-Hydroxy-DMT
Chemical compound
known as 6-(2-fluoroethyl)-LAD or 6-(2-fluoroethyl)-6-nor-LSD, is a lysergamide derivative. It was first proposed by Alexander and Ann Shulgin in their
FLUORETH-LAD
South American psychoactive decoction
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Ayahuasca
Serotonergic compound
Barettin BML-190 (indomethacin morpholinylamide) Cyclic 3-OHM Ergolines and lysergamides (e.g., LSD) Harmala alkaloids and β-carbolines (e.g., 5-methoxyharmalan
4-HO-TMT
Pharmaceutical compound
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
2C-DB
Index of plants with the same common name
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
San_Pedro_cactus
Index of chemical compounds with the same name
Iboga alkaloids β-Carbolines Harmala alkaloids Ergolines Lysergamides Simplified/partial lysergamides Phenethylamines (methoxyphenethylamines) 2Cs 25-NB/NBOMes
Methylxanthines
Mushrooms containing psychoactive indole alkaloids
Lysergamides No substitutions: Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA) Amide-substituted lysergamides: DAL DAM (DAM-57) DiPLA
Psilocybin_mushroom
travel, tourism, insurance
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