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Dopaminergic medication
Levodopa, also known as L-DOPA, is a dopaminergic medication which is used in the treatment of Parkinson's disease (PD) and certain other conditions like
Levodopa
Parkinson's medication
Carbidopa/levodopa, sold under the brand name Sinemet among others, is a fixed-dose combination used for the treatment of Parkinson's disease. It contains
Carbidopa/levodopa
Chemical compound
l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants and animals
L-DOPA
Movement disorder
Levodopa-induced dyskinesia (LID) is a form of dyskinesia associated with levodopa (L-DOPA), used to treat Parkinson's disease. It often involves hyperkinetic
Levodopa-induced_dyskinesia
Progressive neurodegenerative disease
with levodopa to mitigate these effects. Long-term levodopa use may also induce dyskinesia and motor fluctuations. Although this often causes levodopa use
Parkinson's_disease
Chemical compound
treatment of Parkinson's disease. Entacapone together with levodopa and carbidopa allows levodopa to have a longer effect in the brain and reduces Parkinson's
Entacapone
Chemical compound
the peripheral nervous system, preventing the premature conversion of levodopa to dopamine outside the brain. Because carbidopa cannot cross the blood-brain
Carbidopa
Anti Parkinson medicine
Carbidopa/levodopa/entacapone, sold under the brand name Stalevo among others, is a dopaminergic fixed-dose combination medication that contains carbidopa
Carbidopa/levodopa/entacapone
Combination medication
aromatic amino acid and prodrug for levodopa that was developed by AbbVie. Its structure is identical to carbidopa/levodopa except for the replacement of a
Foscarbidopa/foslevodopa
Medication
It also methylates levodopa. COMT inhibitors are indicated for the treatment of Parkinson's disease in combination with levodopa and an aromatic L-amino
Catechol-O-methyltransferase inhibitor
Catechol-O-methyltransferase_inhibitor
Medication
Levodopa/benserazide, sold under the brand name Prolopa among others, is a fixed-dose combination medication used for the treatment of Parkinson's disease
Levodopa/benserazide
Category of movement disorders
of 2017.[relevant?] Levodopa-induced dyskinesia (LID) is evident in patients with Parkinson's disease who have been on levodopa (L‑DOPA) for prolonged
Dyskinesia
Chemical compound
brand name Ongentys, is a medication which is administered together with levodopa in people with Parkinson's disease. Opicapone is a catechol-O-methyltransferase
Opicapone
Treatment of Parkinson's disease
Parkinson's. The main families of drugs useful for treating motor symptoms are levodopa, dopamine agonists, and MAO-B inhibitors. The most commonly used treatment
Management of Parkinson's disease
Management_of_Parkinson's_disease
Chemical compound
also known as levodopa methyl ester (LDME) and sold under the brand name Levomet, is a dopaminergic agent. It is the methyl ester of levodopa. It is used
Melevodopa
Medical condition of the brain
the accumulation of tau protein within the brain. Medications such as levodopa and amantadine may be useful in some cases. PSP was first described by
Progressive supranuclear palsy
Progressive_supranuclear_palsy
Chemical compound
developed as a treatment for Parkinson's disease. It is the ethyl ester of levodopa. It was never marketed. Melevodopa Foslevodopa XP-21279 Djaldetti R, Giladi
Etilevodopa
Investigational Parkinson's disease drugs
tomography (PET) enhancer – diagnosis [1] Levodopa/carbidopa subcutaneous (ND-0612; ND-0680) – combination of levodopa (dopamine precursor) and carbidopa (aromatic
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Neuralogical disorder caused by long-term use of dopaminergic drugs
may have efficacy in controlling the symptoms of levodopa-induced DDS that arise from the use of levodopa for the treatment of Parkinson's disease. DDS is
Dopamine dysregulation syndrome
Dopamine_dysregulation_syndrome
Mental disorder
prolonged use of levodopa, the delusions occupy almost all of a patient's attention. In experimental studies, when the concentration of levodopa decreases,
Fregoli_delusion
Medication used to treat dyskinesia
extended-release formulation was approved for use in the treatment of levodopa-induced dyskinesia. Amantadine was initially developed to prevent replication
Amantadine
Surgical procedure
the uncontrolled movements that can occur in patients taking the drug levodopa for a long time. Thalamotomy can be performed in an invasive or noninvasive
Thalamotomy
Class of enzymes
substrates of COMT. Specific reactions catalyzed by COMT include: L-DOPA (levodopa) → 3-O-methyldopa Dopamine → 3-methoxytyramine DOPAC → HVA (homovanillic
Catechol-O-methyltransferase
Chemical compound often used as medication
Benserazide is used in the management of Parkinson's disease in combination with levodopa as co-beneldopa (BAN), under the brand names Madopar in the UK and Prolopa
Benserazide
Chemical compound
reduced risk for motor complications in Parkinson patients relative to levodopa. DHEC, like other dopamine agonists, aims to mimic the endogenous neurotransmitter
Dihydroergocryptine
Sustained-release levodopa prodrug
XP-21279 is a sustained-release levodopa (L-DOPA) prodrug and hence a dopamine precursor and non-selective dopamine receptor agonist which was under development
XP-21279
Neurosurgical treatment
normal Levodopa therapy, reducing dyskinesias. An indirect systems analysis compared the DBS to the STN, DBS of the GPi, subthalamotomy, jejunal levodopa, and
Deep_brain_stimulation
Phenopicolinic acid • Tropolone L-Phenylalanine → L-tyrosine → L-DOPA (levodopa) Ferrous iron (Fe2+) • Tetrahydrobiopterin • Vitamin B3 (niacin, nicotinamide
List_of_dopaminergic_drugs
Compound that activates dopamine receptors
starts with an amino acid, called L-tyrosine. In the second stage L-DOPA (levodopa) is formed by adding a phenol group to the benzene ring of L-tyrosine.
Dopamine_agonist
Structure in the basal ganglia of the brain
fields of neuropharmacology and toxicology. Various compounds such as levodopa and MPTP are used in the treatment and study of Parkinson's disease, and
Substantia_nigra
Pharmaceutical compound
concentration = 100–1,000 nM). The drug reduces levodopa-induced dyskinesia and enhances levodopa's antiparkinsonian effects in rodents and monkeys.
Fipamezole
Combination dopaminergic medication
taken orally in the form of tablets. Levodopa/carbidopa Foscarbidopa/foslevodopa Levodopa/carbidopa/entacapone Levodopa/benserazide "Melevodopa: Uses, Interactions
Melevodopa/carbidopa
Species of flowering plant
Retrieved 2008-03-15. Pulikkalpura H, Kurup R, Mathew PJ, Baby S (June 2015). "Levodopa in Mucuna pruriens and its degradation". Scientific Reports. 5 (1) 11078
Mucuna_pruriens
Synthetic amino acid/norepinephrine prodrug
α- and β-adrenergic receptors. Unlike norepinephrine, but similarly to levodopa (L-DOPA), droxidopa is capable of crossing the protective blood–brain barrier
Droxidopa
Pharmaceutical compound
previously under development by Kyowa Kirin as a monotherapy and adjunctive to levodopa therapy in Parkinsonism. It reached phase 2 clinical trials prior to the
Sipagladenant
Medical condition
include dehydration, agitation, and catatonia. Rapidly decreasing the use of levodopa or other dopamine agonists, such as pramipexole, may also trigger the condition
Neuroleptic malignant syndrome
Neuroleptic_malignant_syndrome
Organic chemical that functions both as a hormone and a neurotransmitter
substantia nigra. Its metabolic precursor L-DOPA can be manufactured; Levodopa, a pure form of L-DOPA, is the most widely used treatment for Parkinson's
Dopamine
Chemical compound
inhibitor makes COMT main metabolic pathway catalyzing this conversion of Levodopa. This process is catalyzed by catechol O-methyltransferase methylates (COMT)
3-O-Methyldopa
Pharmaceutical compound
development for the treatment of drug-induced dyskinesia, specifically levodopa-induced dyskinesia in people with Parkinson's disease. It is taken orally
Buspirone/zolmitriptan
Chemical compound
640; NLX-112) is an experimental drug being studied for the treatment of levodopa-induced dyskinesia. It is a potent and selective 5-HT1A receptor full agonist
Befiradol
Bilateral pathway in the brain
acetylcholine (ACh) in the dorsal striatum, and not just dopamine deficiency. Levodopa-induced dyskinesias (LID) is a complication associated with long-term use
Nigrostriatal_pathway
Chemical compound
Parkinson's disease in the early phase; Combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's
Cabergoline
23 MORENA
melatonin, while the amino acids L-phenylalanine, L-tyrosine, and L-DOPA (levodopa) are precursors of dopamine, epinephrine (adrenaline), and norepinephrine
Monoamine_precursor
Chemical compound
Foslevodopa is a medication which acts as a prodrug for levodopa, originally invented in the 1980s but not developed for medical use at that time. It is
Foslevodopa
Type of gait due to Parkinson's disease
related to rhythm, are Dopa-resistant. Effect on falls and freezing of gait: Levodopa treatment decreases the frequency and the akinetic type of FOG, with a
Parkinsonian_gait
were the only treatments until the arrival of levodopa, which reduced their use dramatically. Levodopa was first synthesized in 1911 by Casimir Funk,
History of Parkinson's disease
History_of_Parkinson's_disease
American biotechnology company
drugs Inbrija (levodopa inhalation powder) and Ampyra (dalfampridine) in the United States. Ampyra (dalfampridine) Inbrija (levodopa inhalation powder)
Acorda_Therapeutics
Disorder of diminished motivation
dopamine. Some patients with akinetic mutism have shown to improve with levodopa or dopamine agonist therapy, or by increasing dopaminergic transmission
Akinetic_mutism
Dopamine agonist medication
syndrome. In Parkinson's disease it may be used alone or together with levodopa. It is taken by mouth. Pramipexole is a dopamine agonist of the non-ergoline
Pramipexole
Medication
Carbidopa/oxitriptan is analogous to carbidopa/levodopa, which contains carbidopa and the dopamine precursor levodopa (L-DOPA) and is approved and used to elevate
Carbidopa/oxitriptan
Chemical compound
d-DOPA (D-3,4-dihydroxyphenylalanine; dextrodopa) is similar to L-DOPA (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's
D-DOPA
Chemical compound
Dimethoxyamphetamine Dimethylamphetamine Dobutamine DOPA (Dextrodopa, Levodopa) Dopamine Dopexamine Droxidopa EBDB Ephedrine Epinephrine Epinine Etafedrine
Ampyzine
Drug which blocks dopamine receptors
progression in Huntington's disease Mesdopetam is under development for levodopa-induced dyskinesia and psychosis in people with Parkinson's disease Beaulieu
Dopamine_antagonist
Pharmaceutical compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
ST-148_(D2L_antagonist)
Medical condition
fluphenazine, olanzapine), carbamazepine, chloroquine, cisplatin, diazoxide, levodopa, lithium, metoclopramide, lurasidone, domperidone, nifedipine, pemoline
Oculogyric_crisis
Manganese poisoning
symptoms; for example, the nature of the tremors, response to drugs such as levodopa, and affected portion of the basal ganglia. Symptoms are also similar to
Manganism
Syndrome characterized by tremor, slowed movements, rigidity, and imbalance
v t e Antiparkinson agents (N04) Dopaminergics DA precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa
Parkinsonism
Chemical compound
(PD), as an adjunct to levodopa, in a few countries such as Japan. In Japan, zonisamide has been used as an adjunct to levodopa treatment since 2009. In
Zonisamide
Pharmaceutical compound
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
DEMPDHPCA
Hormone used as a medicine
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Epinephrine_(medication)
Compulsive performance of repetitive, mechanical tasks
patients with Parkinson's disease, doses of dopaminergic drugs such as levodopa must be reduced; while people addicted to dopaminergic stimulants like
Punding
Typical antipsychotic medication
result Guanethidine: antihypertensive action antagonized Levodopa: decreased action of levodopa Lithium: rare cases of the following symptoms have been
Haloperidol
Beta blocker medication
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Atenolol
Chemical compound
treatment of Parkinson's disease as an adjunct to levodopa/carbidopa or levodopa/benserazide medications. Levodopa is a prodrug for dopamine, which reduces Parkinson
Tolcapone
Chemical compound
counteracting the dyskinesias associated with long-term treatment with levodopa and related drugs. Kovács G, Kocsis P, Tarnawa I, Horváth C, Szombathelyi
Besonprodil
American publicly traded generics and specialty pharmaceutical company
filed for FDA approval of a new specialty drug labeled IPX-203, (carbidopa-levodopa) which is designed to help control symptoms in Parkinson's disease patients
Amneal_Pharmaceuticals
Pharmaceutical compound
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Cianergoline
Pharmaceutical compound
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Tasipimidine
Pharmaceutical compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
Matsupexole
Pharmaceutical compound
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
4C-TFM
Sleep disorder of unknown cause
orexin agonist may be similarly developed for the treatment of hypersomnia. Levodopa (L-DOPA) is an amino acid and is the precursor to the neurotransmitters
Idiopathic_hypersomnia
Abandoned D1-like receptor antagonist
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
NNC_01-0687
Chemical compound
the brand name Nourianz, is a medication used as an add-on treatment to levodopa/carbidopa in adults with Parkinson's disease (PD) experiencing "off" episodes
Istradefylline
Experimental antiparkinsonian agent and adamantane derivative
AAADTooltip Aromatic L-amino acid decarboxylase Substrates→Products: L-DOPA (levodopa)→Dopamine 5-HTP→Serotonin L-Histidine→Histamine Phenylalanine→Phenethylamine
Hemantane
Experimental enzyme inhibitor
AAADTooltip Aromatic L-amino acid decarboxylase Substrates→Products: L-DOPA (levodopa)→Dopamine 5-HTP→Serotonin L-Histidine→Histamine Phenylalanine→Phenethylamine
Vafidemstat
Dopamine agonist medication
Treatment of Parkinson's disease (PD), either as monotherapy (without levodopa) or in combination with L-DOPA therapy, in the early stages of the disease
Piribedil
Antipsychotic compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
Dexclamol
Medication used to treat high blood pressure
fetus.[citation needed] Difluoromethyldopa D-DOPA (dextrodopa) L-DOPA (levodopa; trade names Sinemet, Pharmacopa, Atamet, Stalevo, Madopar, Prolopa, etc
Methyldopa
Medical condition
as having cerebral palsy. The disorder responds well to treatment with levodopa. The disease typically starts in one limb, typically one leg. Progressive
Dopamine-responsive_dystonia
Chemical compound
AAADTooltip Aromatic L-amino acid decarboxylase Substrates→Products: L-DOPA (levodopa)→Dopamine 5-HTP→Serotonin L-Histidine→Histamine Phenylalanine→Phenethylamine
Carnegine
Reversible monoamine oxidase B inhibitor
taking a stable dose of levodopa (L-dopa) alone or in combination with other Parkinson drugs, to help with "off" episodes when levodopa stops working. Safinamide
Safinamide
Chemical compound
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
2C-T-36
Medication
the required dose of levodopa and thus reduce the motor complications of levodopa therapy. Selegiline delays the point when levodopa treatment becomes necessary
Selegiline
Medication
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Tamsulosin
Wakefulness-promoting drug related to modafinil
Dimethoxyamphetamine Dimethylamphetamine Dobutamine DOPA (Dextrodopa, Levodopa) Dopamine Dopexamine Droxidopa EBDB Ephedrine Epinephrine Epinine Etafedrine
Modafiendz
Pharmaceutical compound
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
2C-tBu
Pharmaceutical compound
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
TGF-8027
Dopaminergic agent
DopAmide, or L-DopAmide, is a synthetic levodopa (L-DOPA) analogue that can serve as a levodopa and dopamine prodrug and is of potential interest in the
DopAmide
Chemical compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
Pharmaceutical compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
Adrogolide
Typical antipsychotic medication
clearance and antagonizes the therapeutic effects of antidiabetic agents, levodopa (a Parkinson's medication. This is likely because chlorpromazine antagonizes
Chlorpromazine
Tocolytic
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Dextrofemine
Topical decongestant
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Oxymetazoline
Genetic neurodegenerative disease
distinguished by Parkinsonian symptoms that respond particularly well to levodopa treatment. Type V appears to resemble Hereditary Spastic Paraplegia; however
Machado–Joseph_disease
Administration of food in the gastrointestinal tract
intestine is for most drugs passive transfer, a few exceptions include levodopa and fluorouracil, which are both absorbed through carrier-mediated transport
Enteral_administration
Pharmaceutical compound
Dipropyldopamine (DPDA) Dopamine Dopexamine Etilevodopa Ibopamine L-DOPA (levodopa) Lu AE04621 Melevodopa L-Phenylalanine L-Tyrosine XP21279 Others: A-68930
A-69024
Substituted amphetamine psychedelic drug
Ethylnorepinephrine Fenclonine Ibopamine Isoprenaline Isoetarine L-DOPA (levodopa) L-DOPS (droxidopa) L-Phenylalanine L-Tyrosine m-Tyramine Metanephrine
2,5-Dimethoxy-4-butylamphetamine
2,5-Dimethoxy-4-butylamphetamine
Substance related to dopamine functions
dietary supplements. L-DOPA (Levodopa), another precursor, is used in the treatment of Parkinson's disease. Prodrugs of levodopa, including melevodopa, etilevodopa
Dopaminergic
Pharmaceutical compound
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Levisoprenaline
Alpha-adrenergic agonist
Etilevodopa Ethylnorepinephrine Ibopamine Indanidine Isometheptene L-DOPA (levodopa) L-Phenylalanine L-Tyrosine Melevodopa Metaraminol Methoxamine Methyldopa
Clonidine
LEVODOPA
LEVODOPA
LEVODOPA
LEVODOPA
Boy/Male
Arabic
Lion
Boy/Male
Hindu, Indian, Marathi
A Rishi
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu
Vanquisher of All Foes
Boy/Male
Irish
Strong man.
Girl/Female
Indian, Telugu
Earth
Boy/Male
Greek
King of the city. Son of Hector killed at Troy.
Boy/Male
Tamil
Earned
Boy/Male
Hindu, Indian
Butterfly
Boy/Male
Tamil
Unnatish | உநà¯à®¨à®¤à¯€à®·
Lord of progress
Boy/Male
Bengali, Indian
Lord Shiva
LEVODOPA
LEVODOPA
LEVODOPA
LEVODOPA
LEVODOPA