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See searches and references containing HYPOXANTHINE!HYPOXANTHINE
Chemical compound
Hypoxanthine is a naturally occurring purine derivative. It is occasionally found as a constituent of nucleic acids, where it is present in the anticodon
Hypoxanthine
Enzyme that converts hypoxanthine to inosine monophosphate
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene. HGPRT is a transferase that catalyzes conversion
Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine_phosphoribosyltransferase
DNA-deoxyinosine glycosylase (EC 3.2.2.15, DNA(hypoxanthine) glycohydrolase, deoxyribonucleic acid glycosylase, hypoxanthine-DNA glycosylase) is an enzyme with systematic
DNA-deoxyinosine_glycosylase
Rare genetic disorder
(LNS) is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This deficiency occurs due
Lesch–Nyhan_syndrome
RNA base pair that does not follow Watson–Crick base pair rules
wobble base pairs are guanine–uracil (G–U), hypoxanthine–uracil (I–U), hypoxanthine–adenine (I–A), and hypoxanthine–cytosine (I–C). In order to maintain consistency
Wobble_base_pair
Chemical reactions and pathways involving lysis of purine nucleotides
phosphorylase acts upon inosine to create hypoxanthine Xanthine oxidase catalyzes the biotransformation of hypoxanthine to xanthine Xanthine oxidase acts upon
Purine_metabolism
Biological molecules constituting nucleic acids
deaminated to IMP from which the ribose unit is removed to form hypoxanthine. Hypoxanthine is oxidized to xanthine and finally to uric acid. Instead of uric
Nucleotide
Nitrogen-containing biological compounds that form nucleosides
complementary bases. Nucleobases such as adenine, guanine, xanthine, hypoxanthine, purine, 2,6-diaminopurine, and 6,8-diaminopurine may have formed in
Nucleotide_base
Medication
enzyme disorders which lead to overproduction of urate, for example: hypoxanthine-guanine phosphoribosyltransferase, including Lesch–Nyhan syndrome; glucose
Allopurinol
Mammalian cell culture medium
HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin
HAT_medium
Chemical compound
It is created from guanine by guanine deaminase. It is created from hypoxanthine by xanthine oxidoreductase. It is also created from xanthosine by purine
Xanthine
Organic compound
oxidase (XO) catalyzes the formation of uric acid from xanthine and hypoxanthine. XO, which is found in mammals, functions primarily as a dehydrogenase
Uric_acid
Heterocyclic aromatic organic compound
particularly rich in hypoxanthine, adenine, and guanine lead to higher blood levels of uric acid. Foods having more than 200 mg of hypoxanthine per 100 g, particularly
Purine
Chemical compound
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. It was
Inosine
Class of enzymes
generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric
Xanthine_oxidase
+ hypoxanthine Thus, the two substrates of this enzyme are 5'-inosinate and H2O, whereas its two products are D-ribose 5-phosphate and hypoxanthine. This
Inosinate_nucleosidase
Excess uric acid in the blood
cause hyperuricemia (see Gout). Foods high in the purines adenine and hypoxanthine may aggravate symptoms of hyperuricemia. Various studies have found higher
Hyperuricemia
Flavor enhancer (621 or E621)
monophosphate Garum Guanosine monophosphate Hydrolyzed vegetable protein Hypoxanthine-guanine phosphoribosyltransferase Inosinic acid Iodized salt Kombu Monopotassium
Monosodium_glutamate
Active ingredient in fermented drinks
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Alcohol_(drug)
Chemical compound
glutamate Monopotassium glutamate Inosinic acid Adenosine monophosphate Hypoxanthine-guanine phosphoribosyltransferase Ribonucleoside CID 20819 from PubChem
Disodium_inosinate
Biological process
phosphoribosyltransferases: adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT). HGPRT is an important enzyme
Nucleotide_salvage
Chemical compound
levels of PRPP are present in Lesch–Nyhan Syndrome. Decreased levels of hypoxanthine guanine phosphoribosyl transferase (HGPRT) causes this accumulation,
Phosphoribosyl_pyrophosphate
Method for producing lots of identical antibodies
ensure they are not secreting antibody themselves and that they lack the hypoxanthine-guanine phosphoribosyltransferase (HGPRT) gene, making them sensitive
Hybridoma_technology
Sulfated glycosaminoglycan (GAG) compound
suspended in water elicit a fear response in many fishes, similar to hypoxanthine-3N-oxide. The basic repeat unit synthesised by the CHSY/CHPF heterocomplex
Chondroitin_sulfate
Species of tree
100–76,000 Catechutannic-acid Choline D-catechin Fat < 30,000 Guanine Hypoxanthine Mucilage Protein < 98,600 Resin < 70,000 Saponin Starch 50,000–60,000
Guarana
Chemical compound
inosinate Inosinic acid Guanosine monophosphate Adenosine monophosphate Hypoxanthine-guanine phosphoribosyltransferase Ribonucleoside "SID 164216535 - PubChem"
Disodium_guanylate
Form of arthritis causing swollen joints
kidney disease, phosphoribosylpyrophosphate synthetase superactivity and hypoxanthine-guanine phosphoribosyltransferase deficiency as seen in Lesch–Nyhan syndrome
Gout
Succession of nucleotides in a nucleic acid
dihydrouridine (D), inosine (I), ribothymidine (rT) and 7-methylguanosine (m7G). Hypoxanthine and xanthine are two of the many bases created through mutagen presence
Nucleic_acid_sequence
Chemical compound
arises by the degradation of adenosine monophosphate, which yields hypoxanthine. Hypoxanthine is then oxidatively catabolized first to xanthine and then to
Hydrogen_peroxide
Removal of an amino group from a molecule
cytosine. Deamination of adenine results in the formation of hypoxanthine. Hypoxanthine, in a manner analogous to the imine tautomer of adenine, selectively
Deamination
Cell division producing haploid gametes
hormone and estradiol likewise promote expression of NPPC and NPR2. Hypoxanthine, a purine apparently originating in the follicle, also inhibits in vitro
Meiosis
Topics referred to by the same term
fish quality. It represents the ratio between the sum of inosine and hypoxanthine to the sum of all other products of ATP degradation. K (disambiguation)
K-value
Chemical compound, medication to treat gout
xanthine oxidase. Xanthine oxidase is needed to oxidize successively hypoxanthine and xanthine to uric acid. Thus, febuxostat inhibits xanthine oxidase
Febuxostat
Chemical compound
Inosinic acid is important in metabolism. It is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides
Inosinic_acid
Process
adenosine deaminase and hydrolyzed by a nucleosidase to form hypoxanthine. Hypoxanthine is subsequently oxidized to xanthine and then to uric acid via
Nucleic_acid_metabolism
Chemical compound
acid Disodium glutamate Monopotassium glutamate Adenosine monophosphate Hypoxanthine-guanine phosphoribosyltransferase Ribonucleoside "The Vegetarian Resource
Guanosine_monophosphate
Genetic modification fusing plants into a hybrid
produced from degradation of nucleic acids. Hypoxanthine is converted into guanine by the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Somatic_fusion
Chemical compound
half-life <10 seconds Excretion can leave cell intact or can be degraded to hypoxanthine, xanthine, and ultimately uric acid Identifiers IUPAC name (2R,3R,4S
Adenosine
Antibodies from clones of the same blood cell
is possible because myeloma cells have lost the ability to synthesize hypoxanthine-guanine-phosphoribosyl transferase (HGPRT), an enzyme necessary for the
Monoclonal_antibody
Metabolic enzyme
does ammonia rise, but after exercise, rises also in serum inosine, hypoxanthine, and uric acid. These studies supported that when the exercise is stopped
Phosphoglucomutase
Plant organelle that conducts photosynthesis
results in base changes. When adenine is deaminated, it becomes hypoxanthine. Hypoxanthine can bind to cytosine, and when the XC base pair is replicated
Chloroplast
British biologist
mice. In this way, transgenic mice with induced mutations in the enzyme Hypoxanthine-guanine phosphoribosyltransferase (HPRT) were created. The HPRT mutations
Martin_Evans
Index of enzymes associated with the same name
may refer to the following enzymes: Adenine phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase This set index page lists enzyme articles associated
Transphosphoribosidase
pH indicator that turns pink in basic solution
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Phenolphthalein
Pharmaceutical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Sipagladenant
Chemical compound
Retrieved 2019-08-16. Gogia, S.; Balaram, H.; Puranik, M. (May 2011). "Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide
Xanthosine_monophosphate
Topics referred to by the same term
is absent Xanthine oxidase, an enzyme that catalyzes the oxidation of hypoxanthine to xanthine Xylenol orange, a chemical indicator for metal ions, used
XO
Chemical compound
Leteprinim (Neotrofin, AIT-082) is a hypoxanthine derivative drug with neuroprotective and nootropic effects. It stimulates release of nerve growth factors
Leteprinim
Mammalian protein found in humans
bind to double-stranded RNA (dsRNA) and convert adenosine to inosine (hypoxanthine) by deamination. ADAR proteins act post-transcriptionally, changing the
ADAR
1999;12(5):263-264. Hu Sheng, et al. "Determination and comparison of between hypoxanthine from various LU produced and Guan Dong produced Di Long" Journal of Chinese
Di_Long_(extract)
Bitter alkaloid of the cacao plant
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Theobromine
DNA located in cellular organelles called chloroplasts
results in base changes. When adenine is deaminated, it becomes hypoxanthine (H). Hypoxanthine can bind to cytosine, and when the HC base pair is replicated
Plastid_DNA
Genus of annelid worms
recognized for its curative effects in the treatment of epilepsy. It contains hypoxanthine, lumbrofebrin, and lumbritin. Pheretima darnleiensis, Kinabalu giant
Pheretima
Alteration in the nucleotide sequence of a genome
place of the original amine group. Examples include C → U and A → HX (hypoxanthine), which can be corrected by DNA repair mechanisms; and 5MeC (5-methylcytosine)
Mutation
glycosylase has been reported to excise 3-methyladenine, 7-methylguanine, hypoxanthine, and 1,N6-ethenoadenine from DNA. "Entrez Gene: MAG1: 3-methyl-adenine
MAG1
Class of chemical compounds
6-methylmercaptopurine), xanthine oxidase (to give 6-thiouric acid], and hypoxanthine phosphoribosyltransferase (to give 6-thioisonine 5'-monphosphate). They
Thiopurine
Species of rodent
Bonvicino, C.R.; et al. (2001). "Induction and characterization of hypoxanthine-phosphoribosyltransferase (Hprt−) deficient cell lines of Akodon cursor
Cursor_grass_mouse
Enzyme
\rightleftharpoons } hypoxanthine + NH3 Thus, the two substrates of this enzyme are adenine and H2O, whereas its two products are hypoxanthine and NH3. This
Adenine_deaminase
Type of glycosyltransferase
transfer of a pentose. Examples include: adenine phosphoribosyltransferase hypoxanthine-guanine phosphoribosyltransferase pertussis toxin poly ADP ribose polymerase
Pentosyltransferase
Pharmaceutical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Vipadenant
acid 98–97–5 C5H4N2O4 orotic acid 65–86–1 C5H4N4O allopurinol 315–30–0 hypoxanthine 68–94–0 C5H4N4O2 xanthine 69–89–6 C5H4N4S mercaptopurine 50–44–2 C5H4O
Glossary_of_chemical_formulae
1998 thriller novel by Richard Preston
this growth. The Cobra virus also knocks out the gene for the enzyme hypoxanthine-guanine phosphoribosyltransferase, whose absence causes Lesch–Nyhan syndrome
The_Cobra_Event
Life that does not originate on Earth
NASA studied meteorites found on Antarctica, finding adenine, guanine, hypoxanthine, and xanthine. Adenine and guanine are components of DNA, and the others
Extraterrestrial_life
Measure of energy in cells
converted by two different pathways to hypoxanthine and ribose-5P, followed by irreversible oxidation of hypoxanthine to uric acid. This helps to buffer the
Energy_charge
Species of flowering plant
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Valerian_(herb)
Pharmaceutical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
YZG-331
Central nervous system stimulant
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Caffeine
Index of chemical compounds with the same molecular formula
0385 u) may refer to: Allopurinol 1-Hydroxy-7-azabenzotriazole (HOAt) Hypoxanthine This set index page lists chemical structure articles associated with
C5H4N4O
Medication for parasite infestations
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Ivermectin
Class of enzymes
5'-S-methyl-5'-thioinosine Pi S-methyl-5-thio-α-D-ribose 1-phosphate + hypoxanthine This is the second step in the catabolism of 5′-methylthioadenosine in
S-methyl-5'-thioinosine phosphorylase
S-methyl-5'-thioinosine_phosphorylase
Drugs to control and prevent gout attacks
through inhibiting xanthine oxidase (enzyme catalyzing the conversion of hypoxanthine to xanthine and further into urate). Allopurinol is generally preferred
Gout_suppressants
Animal flesh eaten as food
surface of the meat. Ongoing proteolysis contributes to conditioning: hypoxanthine, a breakdown product of ATP, contributes to meat's flavor and odor, as
Meat
Medication used to prevent formation of blood clots
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Prasugrel
Chemical compound of RNA
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Uracil
Chemical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Pentoxifylline
Clear liquid secreted from glands in eyes of mammals
phospholipids (1-Palmitoyl-lysophosphatidylcholine), purines and derivatives (Hypoxanthine, Theobromine, uric acid, xanthine), purines and derivatives (4-Pyridoxic
Tears
American geneticist
under the guidance of William Kelley and titled "The Genetic Basis of Hypoxanthine Guanine Phosphoribosyltransferase Deficiency States in Humans." Upon
Beverly_Davidson
Family of large biological molecules
ones being in the TΨC loop of tRNA). Another notable modified base is hypoxanthine, a deaminated adenine base whose nucleoside is called inosine (I). Inosine
RNA
Human disease caused by protist parasites
cost-effective strategies. Comparative homology modelling of the enzyme Hypoxanthine-guanine phosphoribosyl transferase (HGPRT; EC 2.4.2.8) in L. donovani
Visceral_leishmaniasis
Dejerine–Sottas syndrome) HOH Hard of hearing HTN Hypertension HPRT deficiency Hypoxanthine-guanine phosphoribosyl transferase deficiency HPD Histrionic personality
List of abbreviations for diseases and disorders
List_of_abbreviations_for_diseases_and_disorders
Pathological conditions of the kidney, impairing the organ's ability to filter blood
oxidase in the purine degradation pathway. Xanthine oxidase will degrade hypoxanthine to xanthine and then to uric acid. Xanthine is not very soluble in water;
Kidney_disease
Chemical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Tisopurine
American researcher
insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene as a selectable marker
Darrick_Carter
through a series of enzymatic activities. In addition, IMPDH maintains hypoxanthine (HX) levels in the follicular fluid. The HX concentration inhibits cAMP-PDE
Resumption_of_meiosis
H2O ⇌ {\displaystyle \rightleftharpoons } dehypoxanthine futalosine + hypoxanthine This enzyme catalyses the second step of menaquinone biosynthesis. Hiratsuka
Futalosine_hydrolase
Cell line
eliminated, termed CHO-DG44. These DHFR-deficient strains require glycine, hypoxanthine, and thymidine for growth. Cell lines with mutated DHFR are useful for
Chinese_hamster_ovary_cell
Chemical compound
being a polymer of inosinic acid, the other a polymer of cytidylic acid. Hypoxanthine and cytosine form Watson–Crick base pairs, although with less stability
Polyinosinic:polycytidylic acid
Polyinosinic:polycytidylic_acid
Protein metabolic pathway
into uric acid in the following reaction: AMP → Adenosine → Inosine → Hypoxanthine → Xanthine → Uric Acid Myogenic hyperuricemia, as a result of the purine
Purine_nucleotide_cycle
Enzymes involved in base excision repair
(N-methylpurine DNA glycosylase) monofunctional 3-meA(3-alkyladenine), hypoxanthine UDG Ung1 UNG monofunctional uracil Fpg Ogg1 hOGG1 bifunctional 8-oxoG
DNA_glycosylase
Species of bacterium
many aspects including degradation of purines (adenine, xanthine, and hypoxanthine) and casein. Both are also able to ferment similar carbohydrates and
Nocardia_seriolae
Chemical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Quercetin
Growth medium for mammalian cells
5 mg FeSO4 0.83 mg Thiamine hydrochloride 1 mg CuSO4·5H2O 0.0025 mg Hypoxanthine 4 mg ZnSO4·7H2O 0.028 mg Folic acid 1.3 mg NaHCO3 1.2 g Biotechnology
Ham's_tissue_culture_medium
Japanese geneticist
recombination developed by Smithies, Mario Capecchi and others – to correct the hypoxanthine-guanine phosphoribosyltransferase gene responsible for Lesch–Nyhan syndrome
Nobuyo_Maeda
Inactivation of one parent's X chromosome more so than the other's
X-inactivation studies. Other loci used include phosphoglycerate kinase, hypoxanthine phosphoribosyl transferase and the DXS255 locus. If these loci contain
Skewed_X-inactivation
Chemical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Evans_blue_(dye)
Mammalian protein found in humans
enzyme called purine nucleoside phosphorylase (PNP), converting it to hypoxanthine. The proposed mechanism for ADA-catalyzed deamination is stereospecific
Adenosine_deaminase
Derivatives of nucleosides
(OMe, protected NH2, F), nucleosides containing non-canonical bases (hypoxanthine and xanthine contained in natural nucleosides inosine and xanthosine
Nucleoside_phosphoramidite
Chemical compound
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Preladenant
Codrug of amphetamine and theophylline
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
Fenethylline
Protein-coding gene in the species Homo sapiens
ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP GTP Hypoxanthine Inosine IMP IDP ITP Ribose Uracil Uridine UMP UDP UTP Others: Chrysophanol
P2RY6
HYPOXANTHINE
HYPOXANTHINE
HYPOXANTHINE
HYPOXANTHINE
Girl/Female
Tamil
Girl/Female
Arabic
Soft; Cultured
Girl/Female
Indian, Tamil
Goddess Love
Surname or Lastname
English
English : from a pet form of Bobb (see Bubb).
Girl/Female
Arabic, Muslim
Reward; Nice; Cute
Boy/Male
Muslim/Islamic
Jurist
Girl/Female
Tamil
Eternal, Constant
Boy/Male
Gujarati, Hindu, Indian
Lord of Wisdom
Boy/Male
Hindu, Indian
Lord Ganesha
Biblical
that beholds, observes, watches; roof; covering
HYPOXANTHINE
HYPOXANTHINE
HYPOXANTHINE
HYPOXANTHINE
HYPOXANTHINE