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Medical condition
Hyperhomocysteinemia is a medical condition characterized by an abnormally high level of total homocysteine (that is, including homocystine and homocysteine-cysteine
Hyperhomocysteinemia
Chemical compound
substrate. However, excessive levels of homocysteine can result in hyperhomocysteinemia, which is regarded as an indicator of cardiovascular disease risk
Homocysteine
Medical condition
most common genetic cause of elevated serum levels of homocysteine (hyperhomocysteinemia). It is caused by genetic defects in MTHFR, which is an important
Methylenetetrahydrofolate reductase deficiency
Methylenetetrahydrofolate_reductase_deficiency
Vitamin supplement
(cyanocobalamin), and folic acid (folacin). It may be used to treat hyperhomocysteinemia, a medical condition. "Foltx, Generic Name: folacin, cyanocobalamin
Foltx
Purported geroprotective agent
Pinealon has been shown to protect rat offspring from prenatal hyperhomocysteinemia and correspondingly improve post natal cognitive function. Pinealon
Pinealon
Disorder resulting from low blood levels of vitamin B12
low vitamin B12 and folate intakes have shown associations with hyperhomocysteinemia, which is associated with cerebrovascular disease, cognitive decline
Vitamin_B12_deficiency
Rate-limiting enzyme in the methyl cycle
citing "Recent meta-analyses have disproven an association between hyperhomocysteinemia and risk for coronary heart disease and between MTHFR polymorphism
Methylenetetrahydrofolate reductase
Methylenetetrahydrofolate_reductase
Genetic disease
with or without hyperhomocysteinemia (CIMAH) Combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia (CIMAH) - a record
Methylenetetrahydrofolate dehydrogenase 1 deficiency
Methylenetetrahydrofolate_dehydrogenase_1_deficiency
Blockage of an artery in the lungs
protein C deficiency, protein S deficiency, antithrombin deficiency, hyperhomocysteinemia and plasminogen/fibrinolysis disorders) Acquired thrombophilia (antiphospholipid
Pulmonary_embolism
Abnormally low level of folate (vitamin B9) in the body
transmethylation reaction, leading to an accumulation of homocysteine (hyperhomocysteinemia) and to impaired metabolism of neurotransmitters (especially the
Folate_deficiency
Formation of blood clots inside the blood vessels
coagulation Elevated PAI-1 inhibits physiological breakdown of blood clots Hyperhomocysteinemia altered coagulation Elevated factors II, VIII, IX, XI altered coagulation
Thrombosis
Abstaining from the consumption of meat
animal products risks vitamin B12 deficiency, which can lead to hyperhomocysteinemia, a risk factor for several health disorders, including anemia, neurological
Vegetarianism
Chemical elements essential for life
seafood, also fermented foods compromised glutathione synthesis / hyperhomocysteinemia Bromine NE (trace); NE (trace) NE; NE Important to basement membrane
Mineral_(nutrient)
American biochemist emeritus
and the characterization of the C677T polymorphism associated with hyperhomocysteinemia in humans. The polymorphism can lead to a high amount of homocysteine
Rowena_Green_Matthews
Type of white matter abnormality near the lateral ventricles
cause of the imaging findings. Hypertension, smoking, diabetes, hyperhomocysteinemia, and heart diseases are all risk factors for leukoaraiosis. Leukoaraiosis
Leukoaraiosis
Metabolic pathway involving the transfer of a thiol group
known as homocystinuria, an outcome of higher homocysteine levels (hyperhomocysteinemia). All four transsulfuration enzymes require vitamin B6 in its active
Transsulfuration_pathway
Skeletal disorder
Wagner A, Taban-Shomal O, Widmann T, et al. (2007). "The role of hyperhomocysteinemia as well as folate, vitamin B(6) and B(12) deficiencies in osteoporosis:
Osteoporosis
Mammalian protein found in humans
result in hyperhomocysteinemia with complications in the cardiovascular system leading to early and aggressive arterial disease. Hyperhomocysteinemia also
Cystathionine_beta_synthase
Medical condition in which superficial veins become large and twisted
recurrent varicose veins. Varicose veins could also be caused by hyperhomocysteinemia in the body, which can degrade and inhibit the formation of the three
Varicose_veins
Chemical compound
metabolism: folate cycle, methionine cycle, trans-sulfuration and hyperhomocysteinemia. 5-MTHF: 5-methyltetrahydrofolate; 5,10-methyltetrahydrofolate; BAX:
Levomefolic_acid
Formation of a blood clot in a deep vein
free protein S, activated protein C resistance, homocystinuria, hyperhomocysteinemia, high fibrinogen levels, high factor IX levels, and high factor XI
Deep_vein_thrombosis
Human chromosome
neuropathy Holocarboxylase synthetase deficiency Homocystinuria Hyperhomocysteinemia Hypotrichosis Immunodeficiency Inflammatory bowel disease Intellectual
Chromosome_21
Abnormal narrowing of arteries other than those that supply the heart or brain
atherosclerosis risk factor (smoking, dyslipidemia, hypertension, or hyperhomocysteinemia) Individuals with an abnormal lower extremity pulse examination Those
Peripheral_artery_disease
Mammalian protein found in humans
reductase can directly result in elevated levels of homocysteine (hyperhomocysteinemia), which is associated with blindness, neurological symptoms, and
Methionine_synthase
Medical condition
YS, Ouhtit A (July 2012). "Folate and vitamin B12 deficiency and hyperhomocysteinemia promote oxidative stress in adult type 2 diabetes". Nutrition. 28
Complications_of_diabetes
Disorder of amino acid metabolism
of Egypt, may have had homocystinuria. Cystinuria DNA methylation Hyperhomocysteinemia Online Mendelian Inheritance in Man (OMIM): 236200 "Homocystinuria"
Homocystinuria
Chemical compound
metabolism: folate cycle, methionine cycle, trans-sulfuration and hyperhomocysteinemia. 5-MTHF: 5-methyltetrahydrofolate; 5,10-methylenetetrahydrofolate;
5,10-Methylenetetrahydrofolate
5,10-Methylenetetrahydrofolate
Toxin harmful to nervous tissue
doi:10.4049/jimmunol.175.10.6893. PMID 16272348. Bleich, S (2003). "Hyperhomocysteinemia as a New Risk Factor for Brain Shrinkage in Patients with Alcoholism"
Neurotoxin
Pharmaceutical compound
Endothelial dysfunction associated with diabetic peripheral neuropathy, Hyperhomocysteinemia. Metanx package insert, 2014 Smith HS, Pappagallo M (2012). "Metanx:
Metanx
Rare neural tube defect characterised by fusion of the occiput with the spine
nutrition, low parity, and lack of folic acid supplementation, and/or hyperhomocysteinemia have shown to be at larger risk. Animal studies have shown that administration
Iniencephaly
Chemical compound
severe functional deficiency of pyridoxal phosphate and the resultant hyperhomocysteinemia. However, it continues to be researched as a potential agent for
Azaribine
Chemical compound
chronic kidney failure and uremic patiens. It likely contributes to hyperhomocysteinemia and impaired hydrogen sulfide biosynthesis. Lanthionine retention
Lanthionine
Chemical compound
ISSN 1432-1459. Isber S (2007). The role of poor nutritional status and hyperhomocysteinemia in complicated pregnancy in Syria (PDF) (doctoralThesis). doi:10
Methylmalonic_acid
Class of antimetabolite medications
acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during long-term, low-dose methotrexate therapy for rheumatoid arthritis:
Antifolate
Enzyme
Koning, A. B.; Werstuck, G. H.; Zhou, J.; Austin, R. C. (2003). "Hyperhomocysteinemia and its role in the development of atherosclerosis". Clinical Biochemistry
Adenosine_kinase
Indian physicist
Maitree (2015). "Association of MTHFR 677C>T genetic polymorphism with hyperhomocysteinemia in type 2 diabetes patients". Cogent Medicine. 2. doi:10.1080/2331205X
Maitree_Bhattacharyya
Biological process
this global hypomethylation is elevated homocysteine levels causing hyperhomocysteinemia, a known risk factor for cardiovascular disease. High plasma levels
DNA_methylation
Blood clot (thrombus) that forms within a vein
protein S Activated protein C resistance High factor VIII levels Hyperhomocysteinemia High fibrinogen levels High factor IX levels High factor XI levels
Venous_thrombosis
Health effects of long-term alcohol consumption
S2CID 20270541. Bleich S, Bandelow B, Javaheripour K, et al. (January 2003). "Hyperhomocysteinemia as a new risk factor for brain shrinkage in patients with alcoholism"
Long-term_effects_of_alcohol
Medical condition
heredity in a first-degree relative Age > 40 years Pre-eclampsia Hyperhomocysteinemia 2 points Intermediate risk factors Protein S or protein C deficiency
Hypercoagulability in pregnancy
Hypercoagulability_in_pregnancy
Field of study
risk factors for dementia include diabetes, hypertension, smoking, hyperhomocysteinemia, hypercholesterolemia, and obesity (which are usually associated
Neuroscience_of_aging
Private medical college in Telangana, India
Suneetha, N.; Mohanty, Shruti; Rao, Pragna (2008). "Association of hyperhomocysteinemia to alcohol withdrawal in chronic alcoholics". Indian Journal of Clinical
Kamineni Institute of Medical Sciences
Kamineni_Institute_of_Medical_Sciences
Neuron membrane protein
tremor Glaucoma Hepatic encephalopathy Hydroxybutyric aminoaciduria Hyperhomocysteinemia and homocysteinuria Hyperprolinemia Lead encephalopathy Leber's disease
Glutamate_receptor
Chemical compound
2005.12.007. PMID 16414052. Dayal S, Lentz SR (2005). "ADMA and hyperhomocysteinemia". Vasc Med. 10 Suppl 1 (2): S27–33. doi:10.1191/1358863x05vm599oa
Asymmetric_dimethylarginine
066.477 – hyperglycinemia, nonketotic MeSH C18.452.648.066.480 – hyperhomocysteinemia MeSH C18.452.648.066.544 – hyperlysinemias MeSH C18.452.648.066.608
List_of_MeSH_codes_(C18)
Experimental medical technique
hypercholesterolemia, hyperglycemia, hypertension, cardiac hypertrophy, and hyperhomocysteinemia. [citation needed] Animal research and one single human case also
Ischemic_preconditioning
Type of enzymes
PC, Chandel S (April 2019). "Association of vitamin B12 mediated hyperhomocysteinemia with depression and anxiety disorder: A cross-sectional study among
Histone-modifying_enzymes
Medical condition
Carbamoyl-phosphate synthase I deficiency disease Citrullinemia Hyperargininemia Hyperhomocysteinemia Hypermethioninemia Hyperlysinemias Nonketotic hyperglycinemia Propionic
Congenital disorders of amino acid metabolism
Congenital_disorders_of_amino_acid_metabolism
Protein-coding gene in the species Homo sapiens
(Nov 2003). "The role of genetic factors in the development of hyperhomocysteinemia". Clinical Chemistry and Laboratory Medicine. 41 (11): 1427–1434
Haptocorrin
Protein-coding gene in the species Homo sapiens
premature coronary artery disease (CAD) independent of hyperhomocysteinemia. Hyperhomocysteinemia is associated with cerebral, coronary and peripheral atherosclerotic
MTRR_(gene)
Hypergonadotropic ovarian failure, familial or sporadic Hyperhidrosis Hyperhomocysteinemia Hyper-IgD syndrome Hyperimidodipeptiduria Hyperimmunoglobinemia D
List_of_diseases_(H)
Possible prevention methods of dementia
PMID 24959550. Ansari R, Mahta A, Mallack E, Luo JJ (October 2014). "Hyperhomocysteinemia and neurologic disorders: a review". Journal of Clinical Neurology
Prevention_of_dementia
Protein-coding gene in the species Homo sapiens
Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia". J. Biol. Chem. 278 (32): 30317–27. doi:10.1074/jbc.M212897200.
PHLDA1
For example, exposure to vitamin B12 deficient diets can cause hyperhomocysteinemia, which increases oxidative stress within the body leading to the
Exposure_science
combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia (CIMAH). The systematic name of this enzyme class is 5
Methylenetetrahydrofolate dehydrogenase (NADP+)
Methylenetetrahydrofolate_dehydrogenase_(NADP+)
combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia (CIMAH). GRCm38: Ensembl release 89: ENSMUSG00000021048 – Ensembl
MTHFD1
Class of enzymes
stress such as oxidized LDL-cholesterol, inflammatory cytokines, hyperhomocysteinemia, hyperglycemia and infectious agents. Each of these insults attenuates
Dimethylargininase
1 (1): 45. doi:10.4103/2395-5414.157568. Mendelian randomization Hyperhomocysteinemia India portal Biology portal Medicine portal Please see Selected bibliography
Shantanu_Sengupta
Medical condition
antithrombin. Hypercoagulability can be inherited and/or acquired. Hyperhomocysteinemia, a condition known to promote clots, can be caused by a combination
Renal_vein_thrombosis
Field of study
as folate hydrolase 1 and hydroxymethyltransferase 1 along with hyperhomocysteinemia were used as factors contributing to autism to develop an artificial
Epigenetics_of_autism
066.477 – hyperglycinemia, nonketotic MeSH C16.320.565.066.480 – hyperhomocysteinemia MeSH C16.320.565.066.544 – hyperlysinemias MeSH C16.320.565.066.608
List_of_MeSH_codes_(C16)
Medical conditions
1080/003655298750026651. PMID 9867122. Wilcox GM, Mattia AR (2006). "Celiac sprue, hyperhomocysteinemia, and MTHFR gene variants". J. Clin. Gastroenterol. 40 (7): 596–601
Gluten-sensitive enteropathy–associated conditions
Gluten-sensitive_enteropathy–associated_conditions
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
Boy/Male
Indian
Different
Boy/Male
Australian, Latin
Desired
Girl/Female
Muslim
Beautiful, River in bangladesh, Alternatively, Impeccable beauty
Girl/Female
Australian, Danish, French, German, Italian, Latin
Italian Form of Julia; Youthful
Boy/Male
Tamil
Sarvayoni | ஸரà¯à®µà®¯à¯‹à®¨à¯€
Source of everything
Girl/Female
Hindi Indian Sanskrit
A princess.
Boy/Male
Sikh
Ruler of all that is wild and untamed., Born of tooth and fang
Girl/Female
Tamil
Beautiful
Boy/Male
American, Australian, British, Christian, Danish, English, Finnish, German, Greek
Rock; Form of Peter; Stone
Boy/Male
Hindu
Another name of Lord Murugan
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA
HYPERHOMOCYSTEINEMIA