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LANTHIONINE

Lanthionine

Chemical compound

Lanthionine is a nonproteinogenic amino acid with the chemical formula (HOOC-CH(NH2)-CH2-S-CH2-CH(NH2)-COOH). It is typically formed by a cysteine residue

Lanthionine

Lantibiotics

Class of chemical compounds

peptide antibiotics that contain the characteristic thioether amino acids lanthionine or methyllanthionine, as well as the unsaturated amino acids dehydroalanine

Lantibiotics

Lanthionine ketimine

Chemical compound

Lanthionine ketimine (3,4-dihydro-2H-1,3-thiazine-3,5-dicarboxylic acid) is a naturally occurring sulfur amino acid metabolite found in the mammalian

Lanthionine ketimine

Lanthionine_ketimine

Amino acid

Organic compounds containing amine and carboxylic groups

amino acids. For example, some microbes make 2-aminoisobutyric acid and lanthionine, which is a sulfide-bridged derivative of alanine. Both of these amino

Amino acid

Amino_acid

Nisin

Chemical compound

preservative. It has 34 amino acid residues, including the uncommon amino acids lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha), and didehydroaminobutyric

Nisin

Ribosomally synthesized and post-translationally modified peptides

Class of chemical compounds

well-studied families of RiPPs. The family is characterized by the presence of lanthionine (Lan) and 3-methyllanthionine (MeLan) residues in the final natural product

Ribosomally synthesized and post-translationally modified peptides

Ribosomally_synthesized_and_post-translationally_modified_peptides

Omilancor

Pharmaceutical compound

(BT-11) is an experimental drug which acts as an activator of the protein Lanthionine Synthetase C-like 2 (LANCL2). It has antiinflammatory effects and shows

Omilancor

Abscisic acid

Plant hormone

overly optimistic. In mammalian cells ABA targets a protein known as lanthionine synthetase C-like 2 (LANCL2), triggering an alternative mechanism of

Abscisic acid

Abscisic_acid

Cinnamycin

Type B lantibiotic produced by Streptomyces cinnamoneus

acid residues including the unusual amino acids threo-3-methyl-lanthionine, meso-lanthionine, lysinoalanine, and 3-hydroxyaspartic acid. Cinnamycin belongs

Cinnamycin

Dehydroalanine

Chemical compound

amino acids. This activity has made DHA useful synthetically to prepare lanthionine. Dehydroalanine had been proposed as early as 1937, but it was established

Dehydroalanine

Postherpetic neuralgia

Pain due to peripheral nerve damage following infection by the shingles virus

(TRK-700), adapter-associated kinase 1 inhibition ( AAK1) (LX9211), lanthionine synthase C-like protein (LANCL) activation (LAT8881), N-methyl-D-aspartate

Postherpetic neuralgia

Postherpetic_neuralgia

Non-proteinogenic amino acids

Amino acids not naturally encoded in the genome

cysteine or homocysteine forming cystathionine. A similar compound is lanthionine, which can be seen as two alanine molecules joined via a thioether bond

Non-proteinogenic amino acids

Non-proteinogenic_amino_acids

Cystine

Chemical compound

acetylcysteine, induce release of glutamate into the extracellular space. Lanthionine, similar with mono-sulfide link Protein tertiary structure Sullivan reaction

Cystine

Low-sulfur diet

Sulphur Cystine, a proteinogenic amino acid Cystathionine Djenkolic Acid Lanthionine Methionine, a proteinogenic amino acid List of diets Methionine Protein-energy

Low-sulfur diet

Low-sulfur_diet

Bacteriocin

Class of bacterially produced peptide antibiotics

[citation needed] Bacteriocins that contain the modified amino acid lanthionine as part of their structure are called lantibiotics. However, efforts

Bacteriocin

Dehydroamino acid

Lanthionine is the product of the addition of cysteine to dehydroalanine.

Dehydroamino acid

Dehydroamino_acid

LANCL2

Protein-coding gene in the species Homo sapiens

Lu P, Hontecillas R, Philipson CW, Bassaganya-Riera J (Jun 2014). "Lanthionine synthetase component C-like protein 2: a new drug target for inflammatory

LANCL2

Translocase

Class of enzymes

of cystine and a variety of related molecules including djenkolate, lanthionine, diaminopimelate and homocystine. (1) ATP + H2O + L-cystine [cystine

Translocase

Flavoprotein

Protein family

reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond The B chain of dipicolinate

Flavoprotein

LANCL1

Protein-coding gene in the species Homo sapiens

Bartlam M, Hensley K, Li G, Rao Z, Zhang XC (2009). "Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione"

LANCL1

Nuclear Overhauser effect

Nuclear magnetic resonance spectroscopy effect

Tabor, Alethea B. (2024). "The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide". Chemistry – A

Nuclear Overhauser effect

Nuclear_Overhauser_effect

Iphigenia Photaki

Greek organic chemist (1921–1983)

preparation of biologically active atypical peptides such as Nω-arginine or lanthionine-containing peptides. With her expertise on peptide synthesis, Photaki

Iphigenia Photaki

Iphigenia_Photaki

List of investigational headache and migraine drugs

Investigational antimigraine drugs

(AOD9604; Tyr-hGH171191) – human growth hormone protein fragment and lanthionine synthetase C-like protein (LanCL) ligand – migraine [18] LU-AG09222 (ALD-1910)

List of investigational headache and migraine drugs

List_of_investigational_headache_and_migraine_drugs

Lateral Pharma

Australian biotechnology company

Campbell-Galland, Adam; Pickering, Anthony E.; Imlach, Wendy (16 March 2026). "Lanthionine synthetase C-like protein 1 (LanCL1): a therapeutic target for neuropathic

Lateral Pharma

Lateral_Pharma