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HMGA

  • HMGA

    • Family of high mobility group proteins

    HMGA is a family of high mobility group proteins characterized by an AT-hook. They code for a "small, nonhistone, chromatin-associated protein that has

    HMGA

    HMGA

  • Haima 8S

    • Motor vehicle

    was launched in the Chinese market in July 2019 and is based on the Haima HMGA platform (Haima Global Architecture). The Haima 8S was powered by the Boost

    Haima 8S

    Haima 8S

    Haima_8S

  • Haima 7X

    • Motor vehicle

    transmission. The 7X is based on the Haima Global Architecture platform (HMGA). The 7X has 7 seats and a 2+2+3 seat configuration. Astapenko, Elena (22

    Haima 7X

    Haima 7X

    Haima_7X

  • AT-hook

    • DNA-binding motif

    shape around the minor groove of a target DNA strand (pictured at right). HMGA proteins contain three AT-hooks, although some proteins contain as many as

    AT-hook

    AT-hook

    AT-hook

  • HMGA1

    • Protein-coding gene in the species Homo sapiens

    and a C-terminal acidic tail characteristic for the HMG family comprising HMGA, HMGB and HMGN proteins. HMGA1-GFP fusion proteins are highly dynamic in

    HMGA1

    HMGA1

    HMGA1

  • Homeobox

    • DNA pattern affecting anatomy development

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Homeobox

    Homeobox

    Homeobox

  • FOXP2

    • Transcription factor gene of the forkhead box family

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FOXP2

    FOXP2

    FOXP2

  • FOXO3

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FOXO3

    FOXO3

    FOXO3

  • SMAD (protein)

    • Family of proteins

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    SMAD (protein)

    SMAD_(protein)

  • MicroRNA

    • Small non-coding ribonucleic acid molecule

    factor. HMGA proteins (HMGA1a, HMGA1b and HMGA2) are implicated in cancer, and expression of these proteins is regulated by microRNAs. HMGA expression

    MicroRNA

    MicroRNA

    MicroRNA

  • ERCC1

    • Protein-coding gene in humans

    HMGA2 protein. HMGA proteins are characterized by three DNA-binding domains, called AT-hooks, and an acidic carboxy-terminal tail. HMGA proteins are chromatin

    ERCC1

    ERCC1

    ERCC1

  • NFAT

    • Protein family

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NFAT

    NFAT

  • Receptor (biochemistry)

    • Protein molecule receiving signals for a cell

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • Senescence-associated secretory phenotype

    • Phenotype of senescent cells which secrete certain substances

    cellular senescence, and thus to SASP The high-mobility group proteins (HMGA) can induce senescence and SASP in a p53-dependent manner. Activation of

    Senescence-associated secretory phenotype

    Senescence-associated_secretory_phenotype

  • TP63

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    TP63

    TP63

    TP63

  • HIF1A

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    HIF1A

    HIF1A

    HIF1A

  • BAZ1B

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    BAZ1B

    BAZ1B

    BAZ1B

  • Rho factor

    • Prokaryotic protein

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Rho factor

    Rho factor

    Rho_factor

  • Progesterone receptor A

    • Isoform of the progesterone receptor

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Progesterone receptor A

    Progesterone receptor A

    Progesterone_receptor_A

  • Sex-determining region Y protein

    • Protein that initiates male sex determination in therian mammals

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • IRF9

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    IRF9

    IRF9

    IRF9

  • CREB

    • Class of proteins

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    CREB

    CREB

    CREB

  • HES1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    HES1

    HES1

    HES1

  • NF-κB

    • Family of transcription factor protein complexes

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NF-κB

    NF-κB

    NF-κB

  • IRF4

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    IRF4

    IRF4

    IRF4

  • Retinoid receptor

    • Nuclear receptors that bind to retinoids

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Retinoid receptor

    Retinoid_receptor

  • Steroid hormone receptor

    • Group of protein families

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Steroid hormone receptor

    Steroid_hormone_receptor

  • Zinc finger

    • Small structural protein motif found mostly in transcriptional proteins

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Zinc finger

    Zinc finger

    Zinc_finger

  • HMGA2

    • Protein found in humans

    is mediated by an interaction between its second AT-hook and importin-α2. HMGA Lethal dwarfism in rabbits, due to a loss of function (LOF) mutation in the

    HMGA2

    HMGA2

    HMGA2

  • NFE2L1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NFE2L1

    NFE2L1

    NFE2L1

  • PRDM9

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    PRDM9

    PRDM9

    PRDM9

  • T-box transcription factor T

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    T-box transcription factor T

    T-box transcription factor T

    T-box_transcription_factor_T

  • Hypoxia-inducible factor

    • Protein that responds to low oxygen

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • Androgen receptor

    • Mammalian protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • SMAD7

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    SMAD7

    SMAD7

    SMAD7

  • High-mobility group

    • Group of proteins

    into 3 superfamilies each containing a characteristic functional domain: HMGA – contains an AT-hook domain HMGA1 HMGA2 HMGB – contains a HMG-box domain

    High-mobility group

    High-mobility_group

  • SPI1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    SPI1

    SPI1

    SPI1

  • Pax genes

    • Family of transcription factors

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Pax genes

    Pax genes

    Pax_genes

  • P53

    • Mammalian protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    P53

    P53

    P53

  • Glucocorticoid receptor

    • Receptor to which cortisol and other glucocorticoids bind

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • Estrogen receptor

    • Proteins activated by the hormone estrogen

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • Eomesodermin

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Eomesodermin

    Eomesodermin

    Eomesodermin

  • Aryl hydrocarbon receptor

    • Vertebrate receptor protein and transcription factor

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Aryl hydrocarbon receptor

    Aryl hydrocarbon receptor

    Aryl_hydrocarbon_receptor

  • FOSB

    • Protein

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FOSB

    FOSB

    FOSB

  • FOXA2

    • Mammalian protein found in Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FOXA2

    FOXA2

    FOXA2

  • MAF (gene)

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MAF (gene)

    MAF (gene)

    MAF_(gene)

  • NPAS2

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NPAS2

    NPAS2

    NPAS2

  • Protein c-Fos

    • Mammalian protein found in Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Protein c-Fos

    Protein c-Fos

    Protein_c-Fos

  • Retinoblastoma-like protein 2

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Retinoblastoma-like protein 2

    Retinoblastoma-like protein 2

    Retinoblastoma-like_protein_2

  • Cancer epigenetics

    • Field of study in cancer research

    MGMT gene, which reduces protein expression of MGMT. High mobility group A (HMGA) proteins, characterized by an AT-hook, are small, nonhistone, chromatin-associated

    Cancer epigenetics

    Cancer epigenetics

    Cancer_epigenetics

  • Heterochromatin protein 1

    • Protein family

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Heterochromatin protein 1

    Heterochromatin_protein_1

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • FOXP3

    • Immune response protein

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FOXP3

    FOXP3

    FOXP3

  • NFE2L2

    • Human protein and coding gene

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NFE2L2

    NFE2L2

    NFE2L2

  • Transcription factor II H

    • Protein complex

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Transcription factor II H

    Transcription_factor_II_H

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • HOXA13

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    HOXA13

    HOXA13

    HOXA13

  • IKZF3

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    IKZF3

    IKZF3

    IKZF3

  • BCL11B

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    BCL11B

    BCL11B

    BCL11B

  • Homeobox A1

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Homeobox A1

    Homeobox A1

    Homeobox_A1

  • Retinoic acid receptor beta

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Retinoic acid receptor beta

    Retinoic acid receptor beta

    Retinoic_acid_receptor_beta

  • PLAG1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    PLAG1

    PLAG1

    PLAG1

  • Myc

    • Family of regulator genes

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Myc

    Myc

  • Forkhead box D1

    • Human protein-coding gene

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Forkhead box D1

    Forkhead box D1

    Forkhead_box_D1

  • EPAS1

    • Protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    EPAS1

    EPAS1

    EPAS1

  • Sigma factor

    • Protein needed for initiation of transcription in prokaryotes

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Sigma factor

    Sigma_factor

  • Transcription factor

    • Protein that regulates the rate of DNA transcription

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Transcription factor

    Transcription factor

    Transcription_factor

  • FHL1

    • Mammalian protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    FHL1

    FHL1

    FHL1

  • DLX5

    • Mammalian protein found in Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    DLX5

    DLX5

    DLX5

  • Retinoic acid receptor

    • Type of nuclear receptor

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Retinoic acid receptor

    Retinoic acid receptor

    Retinoic_acid_receptor

  • GATA transcription factor

    • Transcription factor

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    GATA transcription factor

    GATA transcription factor

    GATA_transcription_factor

  • ETS transcription factor family

    • Protein family

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    ETS transcription factor family

    ETS transcription factor family

    ETS_transcription_factor_family

  • BZIP domain

    • Protein domain

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    BZIP domain

    BZIP domain

    BZIP_domain

  • Catabolite activator protein

    • Trans-acting transcriptional activator

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Catabolite activator protein

    Catabolite activator protein

    Catabolite_activator_protein

  • General transcription factor

    • Class of protein transcription factors

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    General transcription factor

    General transcription factor

    General_transcription_factor

  • MADS-box

    • Protein family

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MADS-box

    MADS-box

  • Zbtb7

    • Mammalian protein found in Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Zbtb7

    Zbtb7

  • T-box

    • Genes that affect limb and heart development

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    T-box

    T-box

    T-box

  • Germ cell nuclear factor

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Germ cell nuclear factor

    Germ cell nuclear factor

    Germ_cell_nuclear_factor

  • PAX6

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    PAX6

    PAX6

    PAX6

  • Transcription factor Sp3

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Transcription factor Sp3

    Transcription factor Sp3

    Transcription_factor_Sp3

  • SMAD4

    • Mammalian protein found in Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    SMAD4

    SMAD4

    SMAD4

  • Nuclear receptor

    • Protein

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Nuclear receptor

    Nuclear receptor

    Nuclear_receptor

  • HMGN

    • Group of proteins

    chromatin without any known DNA sequence, which is composed of HMGA, HMBG, and HMGN families. HMGA is associated with chromatin throughout the cell cycle, located

    HMGN

    HMGN

  • MXI1

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MXI1

    MXI1

    MXI1

  • Myogenic regulatory factors

    • Group of proteins regulating myogenesis

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Myogenic regulatory factors

    Myogenic_regulatory_factors

  • MTF1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MTF1

    MTF1

    MTF1

  • HIC1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    HIC1

    HIC1

    HIC1

  • MNT (gene)

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MNT (gene)

    MNT (gene)

    MNT_(gene)

  • STAT3

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    STAT3

    STAT3

    STAT3

  • Transcription factor II E

    • Transcription factor

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Transcription factor II E

    Transcription_factor_II_E

  • SOX14

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    SOX14

    SOX14

    SOX14

  • Estrogen receptor alpha

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Estrogen receptor alpha

    Estrogen receptor alpha

    Estrogen_receptor_alpha

  • Small heterodimer partner

    • Protein found in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    Small heterodimer partner

    Small heterodimer partner

    Small_heterodimer_partner

  • MYC

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    MYC

    MYC

    MYC

  • HLX (gene)

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    HLX (gene)

    HLX (gene)

    HLX_(gene)

  • GTF3C1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    GTF3C1

    GTF3C1

    GTF3C1

  • ARID4A

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    ARID4A

    ARID4A

    ARID4A

  • PAX9

    • Protein-coding gene in humans

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    PAX9

    PAX9

    PAX9

  • NRF1

    • Protein-coding gene in the species Homo sapiens

    RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other transcription factors (0.2) HMGI(Y) HMGA 1 2 HBP1 (0.3) Pocket domain Rb RBL1 RBL2 (0.5) AP-2/EREBP-related factors

    NRF1

    NRF1

    NRF1

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