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Hainantoxins (HNTX) are neurotoxins from the venom of the Chinese bird spider Cyriopagopus hainanus. Hainantoxins specifically inhibit tetrodotoxin-sensitive
Hainantoxin
Species of spider
of blocking neurotransmitters, including neurotoxic peptides called hainantoxins. Cyriopagopus hainanus resembles C. schmidti, but can be distinguished
Cyriopagopus_hainanus
Protein structural motif
peptide Albumin I Covalitoxin-II DkTx Grammotoxin GsMTx-4 Guangxitoxin Hainantoxin Hanatoxin Heteroscodratoxin-1 Huwentoxin Maurocalcine Theraphosa leblondi
Inhibitor_cystine_knot
Genus of spiders
Selenocosmia huwena) have had their venom characterized. The last two produce hainantoxins and huwentoxins, respectively. The large fangs can produce puncture wounds
Cyriopagopus
Peptide neurotoxin
Zhonghua (June 2015). "Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated
Protoxin-I
Toxin
the amino acid sequence of Cl6a shows 67% sequence similarity with Hainantoxin (HNTX) III and 97% with huwentoxin (HWTX) I. Cl6a is a selective antagonist
Cl6a
Group of neurotoxic peptides
Liang SP. Mechanism of action of two insect toxins huwentoxin-III and hainantoxin-VI on voltage-gated sodium channels. J Zhejiang Univ Sci B. 2010 Jun;11(6):451-7
Huwentoxin
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