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GANTENERUMAB

  • Gantenerumab

    • Monoclonal antibody protein

    Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease being developed by Hoffmann-La Roche pharmaceuticals. Gantenerumab binds

    Gantenerumab

    Gantenerumab

    Gantenerumab

  • Trontinemab

    • Monoclonal antibody

    Roche/Genentech for the treatment of Alzheimer's disease. It is based on gantenerumab, an anti-amyloid monoclonal antibody, and uses a brainshuttle domain

    Trontinemab

    Trontinemab

  • Donanemab

    • Monoclonal antibody against amyloid beta

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Donanemab

    Donanemab

  • Monoclonal antibody

    • Antibodies from clones of the same blood cell

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Monoclonal antibody

    Monoclonal antibody

    Monoclonal_antibody

  • Humanized antibody

    • Antibodies from non-human species made nearly identical to human ones

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Humanized antibody

    Humanized_antibody

  • Lecanemab

    • Monoclonal antibody against amyloid beta

    Abushakra S, Hey JA, Porsteinsson A, Sabbagh M (August 2020). "Aducanumab, gantenerumab, BAN2401, and ALZ-801-the first wave of amyloid-targeting drugs for Alzheimer's

    Lecanemab

    Lecanemab

  • Caplacizumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Caplacizumab

    Caplacizumab

  • Anti-amyloid antibodies

    • Drug class

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Anti-amyloid antibodies

    Anti-amyloid_antibodies

  • Bapineuzumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bapineuzumab

    Bapineuzumab

  • Evolocumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Evolocumab

    Evolocumab

  • Prasinezumab

    • Experimental monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Prasinezumab

    Prasinezumab

  • Relfovetmab

    • Veterinary medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Relfovetmab

    Relfovetmab

  • Denosumab

    • Human monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Denosumab

    Denosumab

  • Inclacumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Inclacumab

    Inclacumab

  • Amyloid beta

    • Group of peptides

    tested in clinical trials included aducanumab, bapineuzumab, crenezumab, gantenerumab, lecanemab, and solanezumab. Imaging compounds, notably Pittsburgh compound

    Amyloid beta

    Amyloid beta

    Amyloid_beta

  • Bimagrumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bimagrumab

    Bimagrumab

  • Emicizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Emicizumab

    Emicizumab

    Emicizumab

  • Brainshuttle

    • Technology assisting antibody uptake

    consisting of a Brainshuttle module fused to the anti-amyloid antibody gantenerumab, which started a Phase III trial in 2025. It has also been tested with

    Brainshuttle

    Brainshuttle

  • Romosozumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Romosozumab

    Romosozumab

  • Marstacimab

    • Medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Marstacimab

    Marstacimab

  • Bevacizumab

    • Medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bevacizumab

    Bevacizumab

  • Bedinvetmab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bedinvetmab

    Bedinvetmab

    Bedinvetmab

  • Fremanezumab

    • Pharmaceutical biological monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Fremanezumab

    Fremanezumab

  • Semorinemab

    • Anti-tau monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Semorinemab

    Semorinemab

  • Erenumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Erenumab

    Erenumab

    Erenumab

  • Izenivetmab

    • Veterinary medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Izenivetmab

    Izenivetmab

  • Concizumab

    • Medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Concizumab

    Concizumab

  • Galcanezumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Galcanezumab

    Galcanezumab

    Galcanezumab

  • Aducanumab

    • Monoclonal antibody against amyloid beta

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Aducanumab

    Aducanumab

  • Burosumab

    • Monoclonal antibody designed to treat X-linked hypophosphatemia

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Burosumab

    Burosumab

  • Idarucizumab

    • Medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Idarucizumab

    Idarucizumab

  • Ranibizumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ranibizumab

    Ranibizumab

  • Abciximab

    • Pharmaceutical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Abciximab

    Abciximab

    Abciximab

  • Anti-α-synuclein drug

    • Drugs that inhibit α-synuclein

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Anti-α-synuclein drug

    Anti-α-synuclein_drug

  • Trevogrumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Trevogrumab

    Trevogrumab

  • Alzheon

    • A.; Porsteinsson, Anton; Sabbagh, Marwan (2020-08-12). "Aducanumab, gantenerumab, BAN2401, and ALZ-801—the first wave of amyloid-targeting drugs for Alzheimer's

    Alzheon

    Alzheon

  • Alirocumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Alirocumab

    Alirocumab

  • Solanezumab

    • Monoclonal antibody medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Solanezumab

    Solanezumab

  • Abelacimab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Abelacimab

    Abelacimab

  • Eptinezumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Eptinezumab

    Eptinezumab

  • Bococizumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bococizumab

    Bococizumab

  • List of therapeutic monoclonal antibodies

    • human HER2/neu cancer Ganitumab mab human IGF-1 receptor (CD221) cancer Gantenerumab mab human β-amyloid (1-40 and 1-42) Alzheimer's disease Garadacimab Andembry

    List of therapeutic monoclonal antibodies

    List of therapeutic monoclonal antibodies

    List_of_therapeutic_monoclonal_antibodies

  • Icrucumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Icrucumab

    Icrucumab

  • Homotaurine

    • Chemical compound

    ; Porsteinsson, Anton; Sabbagh, Marwan (December 2020). "Aducanumab, gantenerumab, BAN2401, and ALZ-801—the first wave of amyloid-targeting drugs for Alzheimer's

    Homotaurine

    Homotaurine

    Homotaurine

  • Blosozumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Blosozumab

    Blosozumab

  • Faricimab

    • Medication for macular degeneration

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Faricimab

    Faricimab

    Faricimab

  • Ramucirumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ramucirumab

    Ramucirumab

  • Stamulumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Stamulumab

    Stamulumab

  • Opicinumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Opicinumab

    Opicinumab

  • Evinacumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Evinacumab

    Evinacumab

  • Tanezumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Tanezumab

    Tanezumab

  • Crenezumab

    • Antibody tested against Alzheimer's

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Crenezumab

    Crenezumab

  • Cinpanemab

    • Experimental monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Cinpanemab

    Cinpanemab

  • Brolucizumab

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Brolucizumab

    Brolucizumab

  • Refanezumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Refanezumab

    Refanezumab

  • Amlenetug

    • Pharmaceutical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Amlenetug

    Amlenetug

  • Fasinumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Fasinumab

    Fasinumab

  • Ozanezumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ozanezumab

    Ozanezumab

  • Bentracimab

    • Medication

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Bentracimab

    Bentracimab

  • Rinucumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Rinucumab

    Rinucumab

  • Enoticumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Enoticumab

    Enoticumab

  • Fulranumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Fulranumab

    Fulranumab

  • Etaracizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Etaracizumab

    Etaracizumab

  • List of drugs: G

    • (INN) ganglefene (INN) ganirelix (INN) ganitumab (USAN) Ganite Gantanol gantenerumab (USAN, INN) Gantrisin galyfilcon A (USAN) gapicomine (INN) garadacimab

    List of drugs: G

    List_of_drugs:_G

  • Volociximab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Volociximab

    Volociximab

  • Indium (111In) imciromab

    • Pharmaceutical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Indium (111In) imciromab

    Indium_(111In)_imciromab

  • Vanucizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Vanucizumab

    Vanucizumab

  • Nesvacumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Nesvacumab

    Nesvacumab

  • Ascrinvacumab

    • Chemical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ascrinvacumab

    Ascrinvacumab

  • Demcizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Demcizumab

    Demcizumab

  • Orticumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Orticumab

    Orticumab

  • Alacizumab pegol

    • Pharmaceutical drug

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Alacizumab pegol

    Alacizumab_pegol

  • Devextinetug

    • Pharmaceutical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Devextinetug

    Devextinetug

  • Ponezumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ponezumab

    Ponezumab

  • Indium (111In) biciromab

    • Pharmaceutical compound

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Indium (111In) biciromab

    Indium_(111In)_biciromab

  • Ralpancizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Ralpancizumab

    Ralpancizumab

  • Tadocizumab

    • Monoclonal antibody

    Vanucizumab Neurologic Human Anti-amyloid drugs Aducanumab‡ Donanemab Gantenerumab† Lecanemab Erenumab Fasinumab† Fulranumab Opicinumab Humanized Bapineuzumab†

    Tadocizumab

    Tadocizumab

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