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Iron-carrying protein
all subunits of bacterial and archaeal ferritin are H-type and have ferroxidase activity, which means they are able to convert iron from the ferrous
Ferritin
Iron oxidizing enzyme, Fe(II) to Fe(III) conversion
Ferroxidase also known as Fe(II):oxygen oxidoreductase is an enzyme that catalyzes the oxidization of iron II to iron III: 4 Fe2+ + 4 H+ + O2 ⇔ 4 Fe3+
Ferroxidase
Mammalian protein found in Homo sapiens
Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. Ceruloplasmin is the major copper-carrying protein
Ceruloplasmin
Mammalian protein found in Homo sapiens
of iron and possibly copper. It is a transmembrane copper-dependent ferroxidase responsible for transporting dietary iron from intestinal enterocytes
Hephaestin
Protein-coding gene in the species Homo sapiens
Ferritin heavy chain is a ferroxidase enzyme that in humans is encoded by the FTH1 gene. FTH1 gene is located on chromosome 11, and its mutation causes
FTH1
Insufficient level of copper in the body, leading to anaemia and nervous symptoms
caused by impaired iron transport. Hephaestin is a copper-containing ferroxidase enzyme located in the duodenal mucosa that oxidizes iron and facilitates
Copper_deficiency
Medical condition
Aceruloplasminemia is a rare autosomal recessive disorder in which the liver can not synthesize the protein ceruloplasmin properly, which is needed to
Aceruloplasminemia
Duce JA, Tsatsanis A, Cater MA, et al. (8 September 2010). "Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's
Copper_in_biology
Mammalian protein found in humans
that APP has ferroxidase activity in its E2 domain and facilitates export of Fe(II) is possibly incorrect since the proposed ferroxidase site of APP located
Amyloid-beta precursor protein
Amyloid-beta_precursor_protein
Protein-coding gene in the species Homo sapiens
Mitochondrial ferritin is a ferroxidase enzyme that in humans is encoded by the FTMT gene. It is classified as a metal-binding protein which is located
Mitochondrial_ferritin
Iron metabolism in the body
the only known iron exporter in mammals, ferroportin. Hephaestin, a ferroxidase that can oxidize Fe2+ to Fe3+ and is found mainly in the small intestine
Human_iron_metabolism
Protein found in humans
Although the ferritin light chain unlike the ferritin heavy chain has no ferroxidase activity, the light chain may be responsible for the electron transfer
Ferritin_light_chain
Class of enzymes
substrate. Multicopper oxidases include: Ceruloplasmin EC 1.16.3.1 (ferroxidase), a 6-domain enzyme found in the serum of mammals and birds that oxidizes
Multicopper_oxidase
Group of bacterial ferritin proteins that protect DNA against oxidative damage
at the characteristic, highly conserved intersubunit ferroxidase center. The dinuclear ferroxidase centers are located at the interfaces between subunits
DNA-binding protein from starved cells
DNA-binding_protein_from_starved_cells
Use of Iron by organisms
the only known iron exporter in mammals, ferroportin. Hephaestin, a ferroxidase that can oxidize Fe2+ to Fe3+ and is found mainly in the small intestine
Iron_in_biology
Bacterial protein similar to ferritin
four major helices of the subunit, which has been identified as the ferroxidase active site. Bfr from Pseudomonas aeruginosa (PaBfr), unlike other Bfrs
Bacterioferritin
Protein-coding gene in humans
pathway in Saccharomyces cerevisiae, which consists of a multicopper ferroxidase (Fet3) and an iron plasma permease (FTR1) has a high affinity for iron
Natural resistance-associated macrophage protein 2
Natural_resistance-associated_macrophage_protein_2
Medical condition
Malicdan, May Christine V. (2019-05-24). "Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype". PLOS Genetics. 15 (5)
Pili_torti
(NADPH) EC 1.16.1.10: ferric-chelate reductase [NAD(P)H] EC 1.16.3.1: ferroxidase EC 1.16.3.2: bacterial non-heme ferritin EC 1.16.3.3: manganese oxidase
List_of_EC_numbers_(EC_1)
Protein in the mitochondrion mostly expressed in highly metabolic cells
activity ferrous iron binding metal ion binding ferric iron binding ferroxidase activity Cellular component cytoplasm cytosol mitochondrial matrix mitochondrion
Frataxin
Chemical compound
Krutika; Leong, Su Ling; Perez, Keyla; et al. (2010). "Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein is Inhibited by Zinc in Alzheimer's
PBT2
Protein family
maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Hemochromatosis SLC2A4 P14672 Insulin-regulated
Major_facilitator_superfamily
rebound to be transported across the membrane again via both Cu-dependent ferroxidase and Fe(III) transport proteins. Alternatively, ferrous, unchelated iron
Ferric-chelate_reductase
Protein family
ferritin-like proteins as cargo. The operons usually include genes for ferroxidase enzymes, critical for iron oxidation. They belong to the Pfam family
Encapsulin
(Nexo) and the carboxyl terminus in the cytoplasm (Ccyt). Part of the ferroxidase reaction, Fet3p catalyzes the oxidation of Fe(II) to Fe(III) using O2
Fet3p
Scientific discipline
Giuseppe D.; Rogers, Jack T.; Bush, Ashley I. (2010). "Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's
Nutritional_neuroscience
Protein-coding gene in the species Homo sapiens
is vital for the subsequent insertion of copper into ceruloplasmin, a ferroxidase required for iron metabolism, within the golgi apparatus. In addition
ATOX1
≈ 0.1 μM) Fe2+ uptake systems. These systems depend on cell surface ferroxidases to convert extracellular Fe2+ to Fe3+ which can then be taken up via
Iron/lead_transporter
FERROXIDASE
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Male
English
Variant spelling of English Isaac, ISSAC means "he will laugh."
Male
English
Old English name BARTLEY means "Bart's (Bartholomew's) meadow."
Boy/Male
Arabic, Muslim
Patient; Tolerant; Forbearing
Girl/Female
English
A , meaning gift of god. Famous bearer: British writer Dodie Smith, author of the children's...
Girl/Female
Muslim/Islamic
Princess
Male
Hebrew
(יִרְמְיָה) Hebrew name YIRMEYAH means "whom God has appointed." In the bible, this is the name of many characters, including one of the six major prophets. Jeremiah is the Anglicized form.
Boy/Male
Indian, Punjabi, Sikh
One Imbued by the Blissful Soul
Boy/Male
Tamil
House, Mansion, Don of rulers
Male
Egyptian
, a royal scribe.
Boy/Male
Arabic, Muslim
One who Lives in Abtah; A Place Near Makkah
FERROXIDASE
FERROXIDASE
FERROXIDASE
FERROXIDASE
FERROXIDASE