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Protein-coding gene in the species Homo sapiens
F-box only protein 11 is a protein that in humans is encoded by the FBXO11 gene. This gene encodes a member of the F-box protein family which is characterized
FBXO11
Cancer of the lymphatic system
the pathogenesis of Burkitt lymphoma. FBXO11 is a chromatin regulator. By activating ubiquitin ligase, FBXO11 causes ubiquitination of BCL6 which causes
Burkitt_lymphoma
Human chromosome
similarity 98 member A FAM136A: Family with sequence similarity 136 member A FBXO11: F-box protein 11 FTH1P3: encoding protein Ferritin heavy chain 1 pseudogene
Chromosome_2
Transcription factor for converting Naive T cells to TFH
Additionally, post-translational phosphorylation can be affected by mutations in FBXO11. Finally, BCL6’s interaction with other mutated proteins, including CREBBP
BCL6
Q9NRD0 5526 FBXO9 HGNC:13588; Q9UK97 5527 FBXO10 HGNC:13589; Q9UK96 5528 FBXO11 HGNC:13590; Q86XK2 5529 FBXO15 HGNC:13617; Q8NCQ5 5530 FBXO16 HGNC:13618;
List of human protein-coding genes 3
List_of_human_protein-coding_genes_3
Post-translational modification
number of NEDD8 E3 ligases have been described, including RBX1/2, MDM2, FBXO11, RNF111, RanBP2, and TRIM40 among others. RBX1 and RBX2 act as substrate-specific
Neddylation
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