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FACTOR IX

  • Factor IX
  • Protein involved in coagulation

    Factor IX (EC 3.4.21.22) is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency of this protein causes

    Factor IX

    Factor IX

    Factor_IX

  • Haemophilia B
  • Genetic X-linked recessive bleeding disorder

    inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A).

    Haemophilia B

    Haemophilia B

    Haemophilia_B

  • Prothrombin complex concentrate
  • Medication

    known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made up of blood clotting factors II, IX, and X(3-factor

    Prothrombin complex concentrate

    Prothrombin_complex_concentrate

  • Coagulation
  • Process of formation of blood clots

    Willebrand factor (vWF), which is released from the endothelium and from platelets; vWF forms additional links between the platelets' glycoprotein Ib/IX/V and

    Coagulation

    Coagulation

    Coagulation

  • Etranacogene dezaparvovec
  • Gene therapy medication

    gene for clotting Factor IX. The gene is expressed in the liver to produce Factor IX protein, to increase blood levels of Factor IX and thereby limit

    Etranacogene dezaparvovec

    Etranacogene_dezaparvovec

  • Factor X
  • Mammalian protein found in Homo sapiens

    Factor X is synthesized in the liver and requires vitamin K for its synthesis. Factor X is activated, by hydrolysis, into factor Xa by both factor IX

    Factor X

    Factor X

    Factor_X

  • Factor VII
  • Mammalian protein found in humans

    coagulation factor VII), which in turn activates factor IX and factor X. Using genetic recombination a recombinant factor VIIa (eptacog alfa) (trade names include

    Factor VII

    Factor VII

    Factor_VII

  • Haemophilia
  • Genetic disease involving blood clotting

    occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from

    Haemophilia

    Haemophilia

    Haemophilia

  • Factor VIII
  • Blood-clotting protein

    coagulation factor called factor IX. This interaction sets off a chain of additional chemical reactions that form a blood clot. Factor VIII participates in

    Factor VIII

    Factor VIII

    Factor_VIII

  • Factor XI
  • Mammalian protein found in Homo sapiens

    prekallikrein, factor XII, factor XI, and factor IX). Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds. Factor IXa, in

    Factor XI

    Factor XI

    Factor_XI

  • CSL Limited
  • Australian biotechnology company

    factor VIII concentrate Berinin P, freeze-dried human coagulation factor IX concentrate Factor X P Behring, a freeze-dried human coagulation factor IX

    CSL Limited

    CSL Limited

    CSL_Limited

  • Katherine A. High
  • American doctor

    seven years, where she started her career by cloning the normal canine Factor IX gene and then characterizing the mutation in a naturally occurring canine

    Katherine A. High

    Katherine A. High

    Katherine_A._High

  • Marstacimab
  • Medication

    (congenital factor VIII deficiency) without factor VIII inhibitors, or hemophilia B (congenital factor IX deficiency) without factor IX inhibitors. The

    Marstacimab

    Marstacimab

  • X-linked recessive inheritance
  • Mode of inheritance

    clotting disorder caused by a mutation of the Factor IX gene and leading to a deficiency of Factor IX. It is rarer than hemophilia A. As noted above

    X-linked recessive inheritance

    X-linked recessive inheritance

    X-linked_recessive_inheritance

  • Mixing study
  • Type of blood plasma screening test

    in Factor II, Factor VII, Factor IX, and Factor X. Plasma from patients on oral anticoagulants (Warfarin etc.) for 48–72 hours is deficient in Factor VII

    Mixing study

    Mixing_study

  • Tenase
  • Complex formed by blood clotting factors X and V

    Intrinsic tenase complex contains the active factor IX (IXa), its cofactor factor VIII (VIIIa), the substrate (factor X), and they are activated by negatively

    Tenase

    Tenase

  • Adeno-associated virus
  • Species of virus

    Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal

    Adeno-associated virus

    Adeno-associated virus

    Adeno-associated_virus

  • Biotechnology in pharmaceutical manufacturing
  • sequence of the RNA for Factor IX by examining the amino acids in Factor IX: Microsequencing of highly purified... [Factor IX] yielded sufficient amino

    Biotechnology in pharmaceutical manufacturing

    Biotechnology in pharmaceutical manufacturing

    Biotechnology_in_pharmaceutical_manufacturing

  • Thrombophilia
  • Abnormality of blood coagulation increasing the risk of blood clotting (thrombosis)

    factor from damaged tissue. Tissue factor binds to circulating factor VIIa. The combination activates factor X to factor Xa and factor IX to factor IXa

    Thrombophilia

    Thrombophilia

    Thrombophilia

  • Haemophilia in European royalty
  • Genetic disorder in European royalty

    Specifically, they found a single-nucleotide change in the gene for clotting Factor IX that causes incorrect RNA splicing and produces a truncated, nonfunctional

    Haemophilia in European royalty

    Haemophilia in European royalty

    Haemophilia_in_European_royalty

  • Spark Therapeutics
  • American pharmaceutical company

    adeno-associated viral vector which is designed to transfer a working copy of the Factor IX gene into the livers of patients who carry non-functioning copies. It

    Spark Therapeutics

    Spark_Therapeutics

  • Polly and Molly
  • Pair of cloned sheep

    human diseases. The protein in question was the human blood clotting factor IX. Another difference from Dolly the Sheep was the source cell type of the

    Polly and Molly

    Polly_and_Molly

  • Grand Duchess Anastasia Nikolaevna of Russia
  • Youngest daughter of Tsar Nicholas II of Russia (1901–1918)

    dealing with the controversy surrounding Anastasia's death. Hemophilia B (Factor IX Deficiency) Could the Bulgarian mountain village of Gabarevo be the last

    Grand Duchess Anastasia Nikolaevna of Russia

    Grand Duchess Anastasia Nikolaevna of Russia

    Grand_Duchess_Anastasia_Nikolaevna_of_Russia

  • Fidanacogene elaparvovec
  • Gene therapy

    adeno-associated virus used for the treatment of hemophilia B (congenital Factor IX deficiency). Fidanacogene elaparvovec was approved for medical use in

    Fidanacogene elaparvovec

    Fidanacogene_elaparvovec

  • Recombinant factor VIIa
  • Medication

    factor VIIa, which is an activated form of factor VII, bypasses factors VIII and IX and causes coagulation without the need for factors VIII and IX.

    Recombinant factor VIIa

    Recombinant_factor_VIIa

  • Fitusiran
  • Medication

    age and older with hemophilia A or hemophilia B, with or without factor VIII or IX inhibitors (neutralizing antibodies). The US Food and Drug Administration

    Fitusiran

    Fitusiran

  • Princess Victoria of Saxe-Coburg-Saalfeld
  • Mother of Queen Victoria (1786–1861)

    Victoria's Daughters. New York: St. Martin's Press, pp. 43–44 "Hemophilia B (Factor IX)". National Hemophilia Foundation. 2006. Retrieved 20 June 2010. McKusick

    Princess Victoria of Saxe-Coburg-Saalfeld

    Princess Victoria of Saxe-Coburg-Saalfeld

    Princess_Victoria_of_Saxe-Coburg-Saalfeld

  • Gla domain
  • Protein family

    a. coagulation factor II; also its precursor prothrombin) – involved in coagulation Factor VII (F7) – involved in coagulation Factor IX (F9) – involved

    Gla domain

    Gla domain

    Gla_domain

  • Jean-Pierre Lecocq
  • Belgian molecular biologist and entrepreneur (1947–1992)

    vaccination of foxes, and raccoons), recombinant versions of Factor VIII and Factor IX for the treatment of hemophilia A on behalf of the French blood

    Jean-Pierre Lecocq

    Jean-Pierre Lecocq

    Jean-Pierre_Lecocq

  • WHO Model List of Essential Medicines
  • Formulary by the World Health Organization

    Coagulation factor VIII, plasma-derived Coagulation factor IX, plasma-derived Coagulation factor VIII, recombinant Coagulation factor IX, recombinant

    WHO Model List of Essential Medicines

    WHO_Model_List_of_Essential_Medicines

  • Emicizumab
  • Monoclonal antibody

    coagulation factor IX (FIXa) and factor X (FX), bringing these coagulation factors into spatial proximity to facilitate the activation of factor X. This mechanism

    Emicizumab

    Emicizumab

    Emicizumab

  • Transgenesis
  • Introduction of foreign genetic material into a host

    treatment of deficiencies Factor VIII blood clotting factor Factor IX blood clotting factor Fibrinogen blood clotting factor Lactoferrin as an infant formula

    Transgenesis

    Transgenesis

  • Euler's formula
  • Complex exponential in terms of sine and cosine

    correcting a misplaced factor of − 1 {\displaystyle {\sqrt {-1}}} ) as: i x = ln ⁡ ( cos ⁡ x + i sin ⁡ x ) . {\displaystyle ix=\ln(\cos x+i\sin x).} Exponentiating

    Euler's formula

    Euler's formula

    Euler's_formula

  • Bleeding
  • Blood escaping from the circulatory system

    deficiency of Factor VIII causes classic hemophilia A while deficiencies of Factor IX cause "Christmas disease"(hemophilia B). Antibodies to Factor VIII can

    Bleeding

    Bleeding

    Bleeding

  • Hemostatic Powder Spray TC-325
  • Medical intervention

    leads to mechanical tamponade (pressure) and concentration of clotting factors, resulting in enhanced coagulation (clotting of blood). TC-325 was approved

    Hemostatic Powder Spray TC-325

    Hemostatic_Powder_Spray_TC-325

  • Draculin
  • Glycoprotein found in the saliva of vampire bats

    anticoagulant, inhibiting coagulation factors IX (IXa) and X (Xa) by establishing rapid equilibrium with factor Xa, and is the first natural polypeptide

    Draculin

    Draculin

    Draculin

  • F9
  • Topics referred to by the same term

    Financial Reporting, a financial reporting software application Factor IX, a coagulation factor F9, a function key on a computer keyboard Zeolite F-9, a sodium-type

    F9

    F9

  • Title IX
  • US federal law prohibiting sex discrimination in education

    Title IX is a landmark federal civil rights law in the United States that was enacted as part (Title IX) of the Education Amendments of 1972. It prohibits

    Title IX

    Title IX

    Title_IX

  • UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase
  • Class of enzymes

    domain of bovine factor IX(45-87) ⇌ {\displaystyle \rightleftharpoons } UDP + Xylalpha(1-3)Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87) The enzyme

    UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase

    UDP-D-xylose:beta-D-glucoside_alpha-1,3-D-xylosyltransferase

  • Arcturus Therapeutics
  • American biotech firm

    Biological Studies in La Jolla, California, successful delivery of a Factor IX messenger RNA to the liver was reported, which suggested viability of

    Arcturus Therapeutics

    Arcturus Therapeutics

    Arcturus_Therapeutics

  • Fix
  • Topics referred to by the same term

    Information eXchange, a communications and messaging protocol Factor IX, a coagulation factor Spaying and neutering, also called "fixing", sterilization

    Fix

    Fix

  • Factor XII deficiency
  • Medical condition

    factor VIII or antihemophilic globulin, hemophilia B with a deficiency in factor IX (Christmas disease), and hemophilia C with a deficiency in factor

    Factor XII deficiency

    Factor_XII_deficiency

  • Swedish Orphan Biovitrum
  • Swedish pharmaceutical company

    to jointly develop a drug for hemophilia B, a long-lasting recombinant factor IX Fc fusion protein candidate, rFIXFc. This partnership was extended the

    Swedish Orphan Biovitrum

    Swedish Orphan Biovitrum

    Swedish_Orphan_Biovitrum

  • Glycopegylation
  • Examples of glycopegylated molecules include pegozafermin and recombinant factor IX. Behrens, Carsten; Buchardt, Jens (1 January 2020). "12 - Sialyltransferase-mediated

    Glycopegylation

    Glycopegylation

  • Russellysin
  • Fujikawa K, Davie EW (March 1978). "Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease

    Russellysin

    Russellysin

  • ATC code B02
  • Pharmaceutical drug classification

    Coagulation factor IX B02BD05 Coagulation factor VII B02BD06 von Willebrand factor and coagulation factor VIII in combination B02BD07 Coagulation factor XIII

    ATC code B02

    ATC_code_B02

  • Tissue factor
  • Protein involved in coagulation

    activated factor IX and factor VIII. Both pathways lead to the activation of factor X (the common pathway), which combines with activated factor V in the

    Tissue factor

    Tissue factor

    Tissue_factor

  • Concizumab
  • Medication

    hemophilia A (congenital factor VIII deficiency) with factor VIII inhibitors; or hemophilia B (congenital factor IX deficiency) with factor IX inhibitors. In July

    Concizumab

    Concizumab

  • Carboxyglutamic acid
  • Chemical compound

    vitamin K is required to introduce γ-carboxylation of clotting factors II, VII, IX, X and protein Z. In the biosynthesis of γ-carboxyglutamic acid,

    Carboxyglutamic acid

    Carboxyglutamic acid

    Carboxyglutamic_acid

  • Infected blood scandal in the United Kingdom
  • Contamination of blood products with HIV, Hepatitis B and hepatitis C

    C and HIV as a result of receiving infected blood or infected clotting factor products in the United Kingdom. Many of the products were imported from

    Infected blood scandal in the United Kingdom

    Infected blood scandal in the United Kingdom

    Infected_blood_scandal_in_the_United_Kingdom

  • Star Wars: The Rise of Skywalker
  • 2019 film by J. J. Abrams

    Star Wars: The Rise of Skywalker, also known as Star Wars: Episode IX – The Rise of Skywalker, is a 2019 American epic space opera film produced, co-written

    Star Wars: The Rise of Skywalker

    Star_Wars:_The_Rise_of_Skywalker

  • Keith Campbell (biologist)
  • British biologist and university professor (1954–2012)

    March 2006. Retrieved 24 March 2016. Schnieke; et al. (1997). "Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal

    Keith Campbell (biologist)

    Keith_Campbell_(biologist)

  • Christian IX
  • King of Denmark from 1863 to 1906

    Christian IX (8 April 1818 – 29 January 1906) was King of Denmark from 15 November 1863 until his death in 1906. From 1863 to 1864, he was concurrently

    Christian IX

    Christian IX

    Christian_IX

  • Mark A. Kay
  • American physician-scientist known for work in gene therapy

    et al. (2006). Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med. 12:342–347

    Mark A. Kay

    Mark_A._Kay

  • Non-surgical fertility control for dogs and cats
  • Non-surgical methods of avoiding unattended pregnancy in domestic animals

    inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy". Blood. 113 (4): 796–806. doi:10.1182/blood-2008-10-181479

    Non-surgical fertility control for dogs and cats

    Non-surgical_fertility_control_for_dogs_and_cats

  • Sir William Dunn School of Pathology
  • Department in the University of Oxford

    of Chemical Pathology (1978-2008). Cloned and expressed human clotting factor IX, providing a recombinant source of this protein for Haemophilia B patients

    Sir William Dunn School of Pathology

    Sir_William_Dunn_School_of_Pathology

  • Glycoprotein Ib-IX-V complex
  • Membrane receptor

    Willebrand factor (VWF) on damaged sub-endothelium under conditions of high fluid shear stress. Although the primary ligand for the GPIb-V-IX receptor is

    Glycoprotein Ib-IX-V complex

    Glycoprotein_Ib-IX-V_complex

  • Biogen
  • American pharmaceutical company

    development and commercialization of ADUHELM. ALPROLIX™ [Coagulation Factor IX (Recombinant), Fc Fusion Protein] Control and prevention of bleeding episodes

    Biogen

    Biogen

    Biogen

  • Disseminated intravascular coagulation
  • Medical condition where blood clots block small blood vessels

    activated factor VIIa (normally present in trace amounts in the blood), forming the extrinsic tenase complex. This complex further activates factor IX and X

    Disseminated intravascular coagulation

    Disseminated intravascular coagulation

    Disseminated_intravascular_coagulation

  • Horten Ho 229
  • German prototype jet powered flying wing fighter (1944)

    The Horten H.IX, RLM designation Ho 229 (or Gotha Go 229 for extensive re-design work done by Gotha to prepare the aircraft for mass production) was a

    Horten Ho 229

    Horten Ho 229

    Horten_Ho_229

  • Biologist
  • Scientist studying living organisms

    ; Ritchie, M.; Wilmut, I.; Colman, A.; Campbell, K. H. (1997). "Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal

    Biologist

    Biologist

    Biologist

  • Sanofi
  • French multinational pharmaceutical and healthcare company

    with other agents in 2012, marketed by Regeneron. – Hematology Alprolix (Factor IX), for hemophilia B. Arixtra (Fondaparinux), for thrombosis, marketed by

    Sanofi

    Sanofi

    Sanofi

  • Mamushi
  • Species of snake

    purified from Agkistrodon halys blomhoffii, through selective inhibition of factor IX". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1649

    Mamushi

    Mamushi

    Mamushi

  • Biopharmaceutical
  • Drug made from biological source

    in 1982. Major kinds of biopharmaceuticals include: Blood factors (Factor VIII and Factor IX) Thrombolytic agents (tissue plasminogen activator) Hormones

    Biopharmaceutical

    Biopharmaceutical

  • Pharmacokinetics
  • Branch of pharmacology

    kinetics of a drug, it is necessary to have detailed knowledge of a number of factors such as: the properties of the substances that act as excipients, the characteristics

    Pharmacokinetics

    Pharmacokinetics

    Pharmacokinetics

  • Jehovah's Witnesses and blood transfusions
  • Doctrinal position about use of blood

    Clotting factors, including Factor VIII and Factor IX derived from large quantities of stored blood Wound healing factor Erythropoietin (EPO). PolyHeme, a blood

    Jehovah's Witnesses and blood transfusions

    Jehovah's_Witnesses_and_blood_transfusions

  • Antiphospholipid syndrome
  • Immune disorder leading to increased risk of blood clots

    activation pathway factors (factor VIII, factor IX, factor XI and factor XII). Lupus anticoagulant will also rarely cause a factor assay to give a result

    Antiphospholipid syndrome

    Antiphospholipid syndrome

    Antiphospholipid_syndrome

  • Haemophilia A
  • Medical condition

    levels of active clotting factor. Two of the most common differential diagnoses are haemophilia B which is a deficiency in Factor IX and von Willebrand Disease

    Haemophilia A

    Haemophilia A

    Haemophilia_A

  • Prothrombinase
  • Complex that catalyzes conversion of prothrombin to thrombin

    (February 1977). "A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S". Biochemistry. 16 (4): 698–706

    Prothrombinase

    Prothrombinase

  • Blood plasma fractionation
  • Processes of separating the various components of blood plasma

    Plasma Component Reasons for Use factor VIII hemophilia A factor IX hemophilia B Factor X congenital deficiency factor XIII congenital deficiency PCC complex

    Blood plasma fractionation

    Blood_plasma_fractionation

  • George Brownlee
  • British pathologist

    to 2008.[citation needed] Brownlee cloned and expressed human clotting factor IX, providing a recombinant source of this protein for Haemophilia B patients

    George Brownlee

    George_Brownlee

  • A-IX-2
  • Russian explosive

    A-IX-2 (or hexal) is a Russian explosive used in modern Russian military shells. It consists of 73% RDX with 23% aluminium powder, phlegmatized with 4%

    A-IX-2

    A-IX-2

  • Desmopressin
  • Medication

    due to surgery. It is not effective in the treatment of hemophilia B (factor IX deficiency) or severe hemophilia A. May also be used in uremia induced

    Desmopressin

    Desmopressin

    Desmopressin

  • Immuno AG
  • for $715 million. Immuno-manufactured blood products including factor VIII and factor IX such as Kryobulin and Krobulin TIM. In 1983, Immuno sued Dr. Shirley

    Immuno AG

    Immuno_AG

  • SNED1
  • Extracellular matrix protein

    NIDO, was >99% similar to coagulation factor IX, also known as Factor IX (F9). F9 is a secreted coagulation factor involved in the clotting cascade that

    SNED1

    SNED1

  • Deep vein thrombosis
  • Formation of a blood clot in a deep vein

    homocystinuria, hyperhomocysteinemia, high fibrinogen levels, high factor IX levels, and high factor XI levels are associated with increased risk. Other associated

    Deep vein thrombosis

    Deep vein thrombosis

    Deep_vein_thrombosis

  • Fresh frozen plasma
  • Liquid portion of whole blood

    are deficient in the functional vitamin K dependent coagulation factors II, VII, IX, and X, as well as proteins C and S. These functional deficiencies

    Fresh frozen plasma

    Fresh frozen plasma

    Fresh_frozen_plasma

  • Danaparoid
  • Anticoagulant drug

    mechanisms: indirect inactivation of Factor Xa via AT and direct inhibition of thrombin activation of Factor IX (an important feedback loop for thrombin

    Danaparoid

    Danaparoid

  • 1982 in science
  • University of Oxford publish their results of cloning human clotting factor IX. November – Helen House, the world’s first children’s hospice, is set

    1982 in science

    1982_in_science

  • Molecular anthropology
  • Field of anthropology

    off of another population. Oddly, the next X-linked loci they examined, Factor IX, showed a TMRCA of less than 300,000 years. Ancient DNA sequencing had

    Molecular anthropology

    Molecular_anthropology

  • Christmas (surname)
  • Surname list

    have the condition, which is inherited. A deficiency of Factor IX, or: the Christmas factor, also named for Stephen Christmas, causes Christmas disease

    Christmas (surname)

    Christmas_(surname)

  • Mads Krogsgaard Thomsen
  • Danish businessperson

    Recombinant Factor VIIa in Rat Bone: Importance of the Gla‐Domain and Relevance to Factor IX, another Vitamin K‐Dependent Clotting Factor Mads Krogsgaard

    Mads Krogsgaard Thomsen

    Mads_Krogsgaard_Thomsen

  • Glycoprotein Ib
  • Protein found in platelets

    as CD42, is a component of the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet

    Glycoprotein Ib

    Glycoprotein Ib

    Glycoprotein_Ib

  • Sex differences in human physiology
  • disorders include: Red-green colour blindness Haemophilia A (factor VIII) Haemophilia B (factor IX) Duchenne Muscular Dystrophy X-linked agammaglobulinaemia

    Sex differences in human physiology

    Sex differences in human physiology

    Sex_differences_in_human_physiology

  • List of drugs granted breakthrough therapy designation
  • Treatment of adults with moderate to severe hemophilia B (congenital factor IX deficiency) who are receiving routine prophylaxis and without pre-existing

    List of drugs granted breakthrough therapy designation

    List_of_drugs_granted_breakthrough_therapy_designation

  • Calcium-binding EGF domain
  • Protein domain

    crucial for numerous protein-protein interactions. For human coagulation factor IX it has been shown that the calcium-ligands form a pentagonal bipyramid

    Calcium-binding EGF domain

    Calcium-binding EGF domain

    Calcium-binding_EGF_domain

  • Merlin Crossley
  • Australian molecular biologist

    results from mutations that disrupt the control region of the clotting factor IX gene. A testosterone-responsive element accounts for post-pubertal recovery

    Merlin Crossley

    Merlin_Crossley

  • Gene therapy
  • Medical technology

    it works using an adeno-associated virus (AAV) to restore the clotting factor IX (FIX) protein, normal levels of the protein were observed with low doses

    Gene therapy

    Gene therapy

    Gene_therapy

  • Venous thrombosis
  • Blood clot (thrombus) that forms within a vein

    VIII levels Hyperhomocysteinemia High fibrinogen levels High factor IX levels High factor XI levels The overall absolute risk of venous thrombosis per

    Venous thrombosis

    Venous thrombosis

    Venous_thrombosis

  • Jeanne Lusher
  • American physician (1935–2016)

    then, was the development of inhibitors to Factor VIII or Factor IX, which neutralized the activity of the factor given for treatment. Prothrombin complex

    Jeanne Lusher

    Jeanne Lusher

    Jeanne_Lusher

  • Warfarin necrosis
  • Medical condition

    six hours for factor VII and eight hours for protein C, versus one day for factor IX, two days for factor X and two to five days for factor II. The larger

    Warfarin necrosis

    Warfarin necrosis

    Warfarin_necrosis

  • Ohno's law
  • include glucose-6-phosphate dehydrogenase (G6PD), and the genes for Factor VIII and Factor IX. Moreover, no instances were found where an X-linked gene in one

    Ohno's law

    Ohno's_law

  • Niemann–Pick disease type C
  • Medical condition

    McIntosh J, et al. (November 2014). "Long-term safety and efficacy of factor IX gene therapy in hemophilia B". The New England Journal of Medicine. 371

    Niemann–Pick disease type C

    Niemann–Pick disease type C

    Niemann–Pick_disease_type_C

  • Ricardo Dolmetsch
  • Colombian-American neuroscientist and entrepreneur

    Monahan, Paul; Le Quellec, Sandra; Pipe, Steven (2023). "Stable and durable factor IX levels in patients with hemophilia B over 3 years after etranacogene dezaparvovec

    Ricardo Dolmetsch

    Ricardo_Dolmetsch

  • EGF-like domain
  • Protein domain named after the epidermal growth factor protein

    example, point mutations causing defective calcium binding to coagulation factor IX underlies some forms of hemophilia B, and mutations that prevent proper

    EGF-like domain

    EGF-like domain

    EGF-like_domain

  • DBP (gene)
  • Protein-coding gene in the species Homo sapiens

    (February 1993). "Synergy between transcription factors DBP and C/EBP compensates for a haemophilia B Leyden factor IX mutation". Nature Genetics. 3 (2): 175–179

    DBP (gene)

    DBP (gene)

    DBP_(gene)

  • WHO Model List of Essential Medicines for Children
  • Formulary

    Coagulation factor VIII, plasma-derived Coagulation factor IX, plasma-derived Coagulation factor VIII, recombinant Coagulation factor IX, recombinant

    WHO Model List of Essential Medicines for Children

    WHO_Model_List_of_Essential_Medicines_for_Children

  • Bernard–Soulier syndrome
  • Medical condition

    caused by a deficiency of the glycoprotein Ib-IX-V complex (GPIb-IX-V), the receptor for von Willebrand factor. The incidence of BSS is estimated to be less

    Bernard–Soulier syndrome

    Bernard–Soulier syndrome

    Bernard–Soulier_syndrome

  • Royana
  • birth was a great step in the production of transgenic lambs containing factor IX transgenic, which is helpful in human blood clotting. List of cloned animals

    Royana

    Royana

  • Ian Wilmut
  • British embryologist (1944–2023)

    ; Ritchie, M.; Wilmut, I.; Colman, A.; Campbell, K. H. (1997). "Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal

    Ian Wilmut

    Ian Wilmut

    Ian_Wilmut

AI & ChatGPT searchs for online references containing FACTOR IX

FACTOR IX

AI search references containing FACTOR IX

FACTOR IX

  • Castor
  • Surname or Lastname

    English

    Castor

    English : habitational name from places called Caistor, in Lincolnshire and Norfolk, Caister in Norfolk, or Castor in Cambridgeshire, all named with Old English cæster ‘Roman fort or town’.

    Castor

  • FALKOR
  • Male

    Icelandic

    FALKOR

    Perhaps a modern form of Icelandic Fylkir, FALKOR means "people, tribe." 

    FALKOR

  • Sartor
  • Surname or Lastname

    French and Italian

    Sartor

    French and Italian : occupational name from French, northern Italian sartor ‘tailor’ (Latin sartor).English : topographic name denoting someone who lived on land which had been cleared for cultivation, Old French assart, essart ‘woodland cleared for cultivation’ + the habitational suffix -er.

    Sartor

  • ASTOR
  • Male

    French

    ASTOR

     French and German name derived from Occitan astor, ASTOR means "goshawk," itself from Latin acceptor, a variant of accipiter, meaning "hawk." It was originally a derogatory term for men with hawk-like, predatory characteristics.

    ASTOR

  • Pastor
  • Surname or Lastname

    English, Portuguese, Galician, Spanish, Catalan, and French

    Pastor

    English, Portuguese, Galician, Spanish, Catalan, and French : occupational name for a shepherd, Anglo-Norman French pastre (oblique case pastour), Portuguese, Galician, Spanish, Catalan, pastor ‘shepherd’, from Latin pastor, an agent derivative of pascere ‘to graze’. The religious sense of a spiritual leader was rare in the Middle Ages, and insofar as it occurs at all it seems always to be a conscious metaphor; it is unlikely, therefore, that this sense lies behind any examples of the surname.German and Dutch : humanistic name, a Latinized form of various vernacular names meaning ‘shepherd’, for example Hirt or Schäfer (see Schafer).Americanized spelling of Hungarian Pásztor, an occupational name from pásztor ‘shepherd’.

    Pastor

  • KASTOR
  • Male

    Greek

    KASTOR

    (Κάστωρ) Greek name KASTOR means "beaver." In mythology, Castor/Kastor and Pollux/Polydeukes ("very sweet") are the twin sons of Leda and are known as the Gemini twins.

    KASTOR

  • HECTOR
  • Male

    Arthurian

    HECTOR

    , sir Hector de Maris; (defender).

    HECTOR

  • Acton
  • Surname or Lastname

    English

    Acton

    English : habitational name from any of several places, especially in Shropshire and adjacent counties, named Acton. Generally, these are from Old English āc ‘oak’ + tūn ‘settlement’.

    Acton

  • Hector
  • Surname or Lastname

    Scottish

    Hector

    Scottish : Anglicized form of the Gaelic personal name Eachann (earlier Eachdonn, already confused with Norse Haakon), composed of the elements each ‘horse’ + donn ‘brown’.English : found in Yorkshire and Scotland, where it may derive directly from the medieval personal name. According to medieval legend, Britain derived its name from being founded by Brutus, a Trojan exile, and Hector was occasionally chosen as a personal name, as it was the name of the Trojan king’s eldest son. The classical Greek name, Hektōr, is probably an agent derivative of Greek ekhein ‘to hold back’, ‘hold in check’, hence ‘protector of the city’.German, French, and Dutch : from the personal name (see 2 above). In medieval Germany, this was a fairly popular personal name among the nobility, derived from classical literature. It is a comparatively rare surname in France.

    Hector

  • HECTOR
  • Male

    English

    HECTOR

     Anglicized form of Scottish Gaelic Eachann, HECTOR means "brown horse." Compare with another form of Hector.

    HECTOR

  • ACTON
  • Male

    English

    ACTON

    English surname transferred to forename use, ACTON means "oak tree settlement." 

    ACTON

  • H�CTOR
  • Male

    Spanish

    H�CTOR

    Spanish form of Latin Hector, H�CTOR means "defend; hold fast."

    H�CTOR

  • VICTOR
  • Male

    English

    VICTOR

    Roman Latin name VICTOR means "conqueror." 

    VICTOR

  • VÍCTOR
  • Male

    Spanish

    VÍCTOR

    Spanish form of Roman Latin Victor, VÍCTOR means "conqueror."

    VÍCTOR

  • Astor
  • Surname or Lastname

    Southern French and German

    Astor

    Southern French and German : from Occitan astor ‘goshawk’ (from Latin acceptor, variant of accipiter ‘hawk’), used as a nickname characterizing a predacious or otherwise hawklike man. The name was taken to southwestern Germany by 17th-century Waldensian refugees from their Alpine valleys above Italian Piedmont.English : variant spelling of Aster.Astor is the name of a famous American family of industrialists and newspaper owners. John Jacob Astor I (1763–1848) was born at Walldorf near Heidelberg, Germany, the son of a butcher. He followed his brother Henry to New York and made a fortune in the fur trade, which was greatly increased by his descendants in industry, hotels, and newspapers. They built the Waldorf-Astoria Hotel in New York. The great-grandson of John Jacob I, William Waldorf Astor (1848–1919), moved to England in 1890, becoming an influential newspaper proprietor and taking British citizenship in 1899. In 1917 he was created Viscount Astor of Hever. His son, the 2nd Viscount (1879–1952), married Nancy Shaw (née Langhorne) (1879–1964), daughter of a VA planter. She became the first woman to sit in the British House of Commons as a member of Parliament.

    Astor

  • PASTOR
  • Male

    Spanish

    PASTOR

    Spanish name derived from Latin Pastor, PASTOR means "shepherd." St. Pastor was a 9-year-old boy who along with his 13-year-old brother, Justus, was martyred at Alcalá de Henares in the early 4th century.

    PASTOR

  • Actor
  • Boy/Male

    Latin

    Actor

    Son of Azeus.

    Actor

  • NACHOR
  • Male

    Greek

    NACHOR

    (Ναχώρ) Greek form of Hebrew Nachowr, NACHOR means "snoring" or "snorting." In the bible, this is the name of the son of Terah and brother of Abraham.

    NACHOR

  • Facer
  • Surname or Lastname

    English (chiefly Northamptonshire)

    Facer

    English (chiefly Northamptonshire) : probably from the obsolete slang term facer, denoting a braggart or bully. The earliest citation for this term in OED is c. 1515.Americanized spelling of German Feeser.

    Facer

  • Doctor
  • Boy/Male

    English American

    Doctor

    Doctor; teacher.

    Doctor

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Online names & meanings

  • Elvena
  • Girl/Female

    English

    Elvena

    Good elf.

  • Abhyudev
  • Boy/Male

    Indian

    Abhyudev

    Sun

  • Woodie
  • Surname or Lastname

    English

    Woodie

    English : variant spelling of Woody.

  • Youcef
  • Boy/Male

    Arabic, Basque, French, Muslim

    Youcef

    Joseph

  • Pash
  • Surname or Lastname

    English

    Pash

    English : variant of Pask, from the byform pasche, Latin pascha.Americanized spelling of German Pasch.

  • Lodmund
  • Boy/Male

    Norse

    Lodmund

    Blood brother of Bjolf.

  • Eilqar
  • Boy/Male

    Indian

    Eilqar

    Promise

  • Saieswar
  • Boy/Male

    Hindu, Indian

    Saieswar

    Lord Shiva; Saibaba

  • Eulalie
  • Girl/Female

    French American Greek

    Eulalie

    Greek Eulalia, meaning sweetly speaking, well - spoken.

  • Carlie
  • Boy/Male

    Australian, Gaelic

    Carlie

    Small Champion

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Other words and meanings similar to

FACTOR IX

AI search in online dictionary sources & meanings containing FACTOR IX

FACTOR IX

  • Facta
  • pl.

    of Factum

  • Factor
  • n.

    One who transacts business for another; an agent; a substitute; especially, a mercantile agent who buys and sells goods and transacts business for others in commission; a commission merchant or consignee. He may be a home factor or a foreign factor. He may buy and sell in his own name, and he is intrusted with the possession and control of the goods; and in these respects he differs from a broker.

  • Faitour
  • n.

    A doer or actor; particularly, an evil doer; a scoundrel.

  • Factored
  • imp. & p. p.

    of Factor

  • Doctor
  • n.

    Any mechanical contrivance intended to remedy a difficulty or serve some purpose in an exigency; as, the doctor of a calico-printing machine, which is a knife to remove superfluous coloring matter; the doctor, or auxiliary engine, called also donkey engine.

  • Factory
  • n.

    A building, or collection of buildings, appropriated to the manufacture of goods; the place where workmen are employed in fabricating goods, wares, or utensils; a manufactory; as, a cotton factory.

  • Doctor
  • v. t.

    To confer a doctorate upon; to make a doctor.

  • Foetor
  • n.

    Same as Fetor.

  • Factoring
  • p. pr. & vb. n.

    of Factor

  • Ductor
  • n.

    A contrivance for removing superfluous ink or coloring matter from a roller. See Doctor, 4.

  • Vector
  • n.

    Same as Radius vector.

  • Doctor
  • v. t.

    To tamper with and arrange for one's own purposes; to falsify; to adulterate; as, to doctor election returns; to doctor whisky.

  • Falter
  • v. i.

    Hesitation; trembling; feebleness; an uncertain or broken sound; as, a slight falter in her voice.

  • Faytour
  • n.

    See Faitour.

  • Factory
  • n.

    The body of factors in any place; as, a chaplain to a British factory.

  • Facto
  • adv.

    In fact; by the act or fact.

  • Factory
  • n.

    A house or place where factors, or commercial agents, reside, to transact business for their employers.

  • Factor
  • v. t.

    To resolve (a quantity) into its factors.

  • Factor
  • n.

    One of the elements, circumstances, or influences which contribute to produce a result; a constituent.