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EC508

EC508

Chemical compound

EC508, also known as estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline), is an estrogen which is under development by Evestra for use in menopausal

EC508

EC586

Chemical compound

sulfonamide–proline estradiol ester known as EC508, which shows the same properties as EC586. Clinical trials for EC586 and EC508 are undergoing as of 2023. List of

EC586

Pharmacokinetics of estradiol

estradiol cyclooctyl acetate, estradiol 3-saccharinylmethyl ether, and EC508 (estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline)) are estradiol esters

Pharmacokinetics of estradiol

Pharmacokinetics_of_estradiol

List of estrogen esters

17β-propionate)) Estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline) (EC508) Estradiol acetate benzoate Estradiol 17β-acetate Estradiol 17β-benzoate

List of estrogen esters

List_of_estrogen_esters

Ethinylestradiol sulfonate

Estrogenic drug

3-sulfamate (J1034), and estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline) (EC508), which are highly potent oral estradiol prodrugs that bind to erythrocytes

Ethinylestradiol sulfonate

Ethinylestradiol_sulfonate

Steroid ester

Class of chemical compounds

estradiol sulfamate (E2MATE; also a potent steroid sulfatase inhibitor) and EC508 (estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)-L-proline)), the testosterone

Steroid ester

Steroid_ester

List of investigational sex-hormonal agents

inhibitor (androgen synthesis inhibitor) for prostate cancer and breast cancer EC508 – oral prodrug of estradiol (estrogen) with improved pharmacokinetics Erteberel

List of investigational sex-hormonal agents

List_of_investigational_sex-hormonal_agents

Estradiol sulfamate

Steroid sulfatase inhibitor under development

subsequently developed new C17β sulfonamide ester prodrugs of estradiol, such as EC508, that cannot be transformed into the corresponding estrone equivalents and

Estradiol sulfamate