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Chemical compound
macrocycle and the four acetic acid arms in the DOTA structure, while "xetan" is a standard suffix for chelators. DOTA is derived from the macrocycle known as
DOTA_(chelator)
Eight amino-acid long peptide covalently bonded to a DOTA chelator
an eight amino acid long peptide, with a covalently bonded DOTA bifunctional chelator. DOTA-TATE can be reacted with the radionuclides gallium-68 (T1/2
DOTA-TATE
Radiopharmaceutical precursor
linker (composed of 2-naphthyl-l-Ala and cyclohexyl groups), and a DOTA chelator for radiolabeling. Vipivotide tetraxetan is the International Nonproprietary
Vipivotide_tetraxetan
90Y-DOTA-biotin consists of a radioactive substance (yttrium-90) complexed by a chelating agent (DOTA), which in turn is attached to the vitamin biotin
90Y-DOTA-biotin
Chemical compound
Edotreotide (USAN, also known as (DOTA0-Phe1-Tyr3) octreotide, DOTA-TOC, DOTATOC) is a substance which, when bound to various radionuclides, is used in
Edotreotide
Topics referred to by the same term
Rica DOTA (chelator), a chemical Declaration of the Americas on Diabetes (DOTA 1996), a regional declaration following the St. Vincent Declaration DOTA (bus
Dota_(disambiguation)
Radioactive diagnostic agent used in PET scan to localize tumors
Copper (64Cu) oxodotreotide or Copper Cu 64 dotatate, sold under the brand name Detectnet, is a radioactive diagnostic agent used with positron emission
Copper_(64Cu)_oxodotreotide
Organic compound used as a chelator
sometimes known as TCMC) is an organic ligand used as a chelator much like its carboxylic acid analog DOTA, but shows greater selectivity for large covalently
DOTAM
Type of radiotherapy
for imaging). The chelator is the essential link between the radionuclide and peptide. For 177Lu and 90Y this is typically DOTA (tetracarboxylic acid
Peptide receptor radionuclide therapy
Peptide_receptor_radionuclide_therapy
Type of radiation therapy
phaeochromocytoma and neuroblastoma. Lutetium-177 ( 177Lu) is bound with a DOTA chelator to target neuroendocrine tumours. At the Institute for Transuranium
Radionuclide_therapy
Monoclonal antibody
cancer. The antibody itself, tacatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells. "Statement
Yttrium (90Y) tacatuzumab tetraxetan
Yttrium_(90Y)_tacatuzumab_tetraxetan
Index of chemical compounds with the same molecular formula
The molecular formula C16H28N4O8 may refer to: Alcaligin DOTA (chelator), also known as tetraxetan This set index page lists chemical structure articles
C16H28N4O8
Class of pharmaceuticals
Compounds were developed with 3 macrocyclic chelators: DOTA, NODAGA, and CB-TE2A. DOTA had already been used as a chelator in the radiolabeled somatostatin agonists
Somatostatin_inhibitor
Nuclear medicine test that uses gallium to obtain images of tissues
mid-thigh to the base of the skull. 68Ga DOTA conjugated peptides (including 68Ga DOTA-TATE, DOTA-TOC and DOTA-NOC) are used in positron emission tomography
Gallium_scan
Class of chemical compounds
Compounds were developed with 3 macrocyclic chelators: DOTA, NODAGA, and CB-TE2A. DOTA had already been used as a chelator in the radiolabeled somatostatin agonists
Somatostatin receptor antagonist
Somatostatin_receptor_antagonist
Type of medical imaging
ethylenediaminediacetic acid (EDDA) and the other the HYNIC-Tyr3-octreotide chelator and somatostatin analog. Approximately 400-700 MBq may be administered
Octreotide_scan
Isotope of scandium
for further labelling studies. 44Sc complexates with DOTA, a well-established bifunctional chelators conjugated to peptides or other molecular targeting
Scandium-44
Molecule with a ring of bonded atoms
[citation needed] A, the crown ether, 18-crown-6; B, the simple tetra-aza chelator, cyclam; C, an example porphyrin, the unsubstituted porphine; D, a mixed
Cyclic_compound
residues. Another example is to use chelators such DOTA that can be chemically coupled to a protein; the chelator in turn traps radiometals thus radiolabeling
Radioactivity in the life sciences
Radioactivity_in_the_life_sciences
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