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DLX3

  • DLX3
  • Mammalian protein found in Homo sapiens

    that in humans is encoded by the DLX3 gene. Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Dlx3 transcription is mediated through

    DLX3

    DLX3

    DLX3

  • Hair follicle
  • Organ found in mammalian skin

    morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: Alternative mode for Dlx3 induction in mouse keratinocytes". Nucleic Acids

    Hair follicle

    Hair follicle

    Hair_follicle

  • Tricho–dento–osseous syndrome
  • Medical condition

    Tennessee, and North Carolina. The cause of this disease is a mutation in the DLX3 (distal-less 3) gene, which controls hair follicle differentiation and induction

    Tricho–dento–osseous syndrome

    Tricho–dento–osseous syndrome

    Tricho–dento–osseous_syndrome

  • Theria
  • Subclass of mammals in the clade Theriiformes

    "Theria-Specific Homeodomain and cis-Regulatory Element Evolution of the Dlx3–4 Bigene Cluster in 12 Different Mammalian Species". Journal of Experimental

    Theria

    Theria

    Theria

  • List of human transcription factors
  • ENSG00000115844 Homeodomain Known motif – High-throughput in vitro [143] TAATTR DLX3 ENSG00000064195 Homeodomain Known motif – High-throughput in vitro [144]

    List of human transcription factors

    List_of_human_transcription_factors

  • DLX gene family
  • Genes in the DLX family

    two-gene clusters (bigene clusters) with each other. There are DLX1-DLX2, DLX3-DLX4, DLX5-DLX6 clusters in vertebrates, linked to Hox gene clusters HOXD

    DLX gene family

    DLX_gene_family

  • Olfactory epithelium
  • Specialised epithelial tissue in the nasal cavity that detects odours

    regulated downstream expression of transcription factors, such as Pax6, Dlx3, Sox2, and others, within the presumptive olfactory placode are crucial for

    Olfactory epithelium

    Olfactory epithelium

    Olfactory_epithelium

  • Paraspeckle
  • Cell compartment found in the nucleus's interchromatin space

    Dispensable No CPSF6 Dispensable No CPSF7 Important No DAZAP1 Essential Yes DLX3 n.d. Yes EWSR1 Dispensable Yes Yes FAM98A Important Yes FIGN Important Yes

    Paraspeckle

    Paraspeckle

    Paraspeckle

  • Wiedemann–Rautenstrauch syndrome
  • Medical condition

    cause autosomal-recessive Wiedemann-Rautenstrauch syndrome. Am J Hum Genet "DLX3 distal-less homeobox 3 [Homo sapiens (human)]". Gene - National Center for

    Wiedemann–Rautenstrauch syndrome

    Wiedemann–Rautenstrauch syndrome

    Wiedemann–Rautenstrauch_syndrome

  • Homeobox
  • DNA pattern affecting anatomy development

    ANTP-like group. Humans have a "distal-less homeobox" family: DLX1, DLX2, DLX3, DLX4, DLX5, and DLX6. Dlx genes are involved in the development of the nervous

    Homeobox

    Homeobox

    Homeobox

  • DLX4
  • Mammalian protein found in Homo sapiens

    Wright JT, Pettenati MJ, Hart TC (1998). "Identification of a mutation in DLX3 associated with tricho-dento-osseous (TDO) syndrome". Hum. Mol. Genet. 7

    DLX4

    DLX4

    DLX4

  • List of human protein-coding genes 2
  • HGNC:2911; P36957 4318 DLX1 HGNC:2914; P56177 4319 DLX2 HGNC:2915; Q07687 4320 DLX3 HGNC:2916; O60479 4321 DLX4 HGNC:2917; Q92988 4322 DLX5 HGNC:2918; P56178

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

  • List of OMIM disorder codes
  • imperfecta, hypomaturation-hypoplastic type, with taurodontism; 104510; DLX3 Amelogenesis imperfecta, hypoplastic/hypomaturation type; 301200; AMELX Amelogenesis

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

  • Dental follicle
  • Anatomical entity

    the transcription factor ZBTB16 is a target for further investigations. DLX3, a transcription factor, which is related to the induced BMP2 pathway in

    Dental follicle

    Dental follicle

    Dental_follicle

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