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Extinct species of canine mammal
The dire wolf (Aenocyon dirus /aɪˈnɒkaɪ.ɒn ˈdaɪrəs/ ) is an extinct species of canine which was native to the Americas during the Late Pleistocene and
Dire_wolf
Bioengineering project with the goal of replicating an extinct species
Colossal Biosciences dire wolf project is a project by Colossal Biosciences with the goal of replicating the phenotype of the extinct dire wolf (Aenocyon dirus)
Colossal Biosciences dire wolf project
Colossal_Biosciences_dire_wolf_project
Topics referred to by the same term
A dire wolf is an extinct canine. Dire wolf or direwolf may also refer to: Direwolf (Game of Thrones), a fictional creature in George R. R. Martin's A
Dire_wolf_(disambiguation)
American biotechnology company
extinct animals, including the woolly mammoth, the Tasmanian tiger, the dire wolf, the dodo, the moa and the bluebuck. In 2023, it stated that it wants
Colossal_Biosciences
1970 song by Grateful Dead
"Dire Wolf" is a ballad by the Grateful Dead, released as the third track on their 1970 album Workingman's Dead. The lyrics were written by Robert Hunter
Dire_Wolf_(song)
Process of re-creating an extinct organism
been attempts to recreate the dire wolf (Aenocyon dirus) in modern times. The first is a project called the Dire Wolf Project, a project begun in 1988
De-extinction
lineages evolved in isolation from the dire wolf lineage. The study proposes an early origin of the dire wolf lineage in the Americas, and that this geographic
Evolution_of_the_wolf
Genus of canines
distinct dire wolf lineage that had convergently evolved a very similar appearance to members of Canis. True members of Canis, namely the gray wolf and coyote
Canis
American entrepreneur
dire wolf. Romulus, Remus, and Khaleesi were announced publicly, and he appeared on The Joe Rogan Experience that same month to discuss the dire wolf
Ben_Lamm
2020 board game by Paul Dennen
Imperium is a 2020 board game designed by Paul Dennen and published by Dire Wolf Digital. In the board game, which is set in Frank Herbert's Dune universe
Dune:_Imperium
Extinct species of canid
the dire wolf. The sequences indicate the dire wolf to be a highly divergent lineage which last shared a most recent common ancestor with the wolf-like
Canis_edwardii
2007 American TV series
Smilodon fatalis, dire wolf, short-faced bear, American lion, Bison antiquus, Mexican horse, Columbian mammoth, Megalonyx, gray wolf (cameo), grizzly bear
Prehistoric_Predators
2018 asymmetric board game
and was followed by four expansions. A digital version, developed by Dire Wolf Digital, was released in 2020. In Root, 2-4 players compete in an asymmetric
Root_(board_game)
Extinct North American wolf
to its skull size. In comparison with the Beringian wolf, the more southerly occurring dire wolf (Aenocyon dirus) was the same size but heavier and with
Beringian_wolf
Extinct species of carnivore
Early to Middle Pleistocene epoch. It is proposed as the ancestor of the dire wolf, one of the most famous prehistoric carnivores in North America, and likely
Armbruster's_wolf
Species of canine
showed an increase in tooth breakage similar to that seen in the extinct dire wolf. This suggests they either often processed carcasses, or that they competed
Wolf
Name list
the 2018 film Tamizh Padam 2 Khaleesi (wolf) (born 2025), a female genetically modified grey wolf with dire wolf characteristics represented, created by
Khaleesi_(given_name)
1970 album by Grateful Dead
Jerry had been writing; many of them had a decidedly country flavor ('Dire Wolf,' 'Friend of the Devil,' 'High Time,' 'Casey Jones', 'Ripple'), and Jerry
Workingman's_Dead
Family of mammals
cinereoargentus) and the now-extinct dire wolf (Aenocyon dirus). Besides these, there are species endemic to South America: the maned wolf (Chrysocyon brachyurus)
Canidae
Canid native to the southeastern United States
fossil remains of the gray wolf found in the southeastern states. He proposes that following the extinction of the dire wolf, the coyote appears to have
Red_wolf
Extinct species of carnivore
nehringi does not belong to the genus Canis, but may be part of the dire wolf (Aenocyon dirus) lineage, a separate genus, or simply a junior synonym
Canis_nehringi
American filmmaker
Flare Yes No No Bikini Royale Yes Yes No 2009 Silent Venom Yes No No Dire Wolf Yes No No 2010 Twilight Vamps Yes Yes Executive Bikini Frankenstein Yes
Fred_Olen_Ray
Subspecies of grey wolf
and fossil North American wolves. The major limb bones of the dire wolf, Beringian wolf, and most modern North American gray wolves can be clearly distinguished
Mexican_wolf
Extinct subspecies of the gray wolf
excavations of a large canid, which was comparable in size to North American dire wolf, dating the Late Pleistocene from Aomori and Shizuoka prefectures, however
Japanese_wolf
2016 video game
free-to-play online collectible card video game developed and published by Dire Wolf Digital. Eternal is available for iOS, Android, Xbox One, PCs using Steam
Eternal_(video_game)
1996 novel by George R. R. Martin
the first chapter—a young boy seeing a beheading and the discovery of dire wolf pups in "summer snows"—and wrote it in a few days. Over that summer, he
A_Game_of_Thrones
Subtribe of carnivores
Canina is a taxon which represents the wolf-like subtribe of the tribe Canini, and is sister to the subtribe Cerdocyonina. Fossils of this group date to
Canina_(subtribe)
Extinct genus of saber-toothed cat
which S. gracilis preferred soft-skinned browsers. Isotopic studies of dire wolf (Aenocyon dirus) and American lion (Panthera atrox) bones show an overlap
Smilodon
English actress (born 1996)
Turner's Shocking New Role: Actress Teams Up With Colossal Biosciences For Dire Wolf Revival". The Blast. 2 July 2025. "Engineering the Impossible". SXSW London
Sophie_Turner
Clank!: A Deck-Building Adventure is a 2016 board game published by Dire Wolf Digital, Renegade Game Studios and others. Clank!: A Deck-Building Adventure
Clank!: A Deck-Building Adventure
Clank!:_A_Deck-Building_Adventure
American comic book series
Rook: Exodus #7. The arc introduced new Wardens and focused on Rook and Dire Wolf searching for Bloodhound, who may be able to restore Exodus's failing
Rook_(comics)
Extinct genus of canines
(lit. 'dire dog') is an extinct genus of canines that lived between the Pleistocene and early Holocene epochs. The type species is the dire wolf (Aenocyon
Aenocyon
Topics referred to by the same term
Look up dire, diré, or díře in Wiktionary, the free dictionary. Dire may refer to: Diré, a town in Tombouctou Region, Mali Diré Cercle, an administrative
Dire
Role-playing game system
Cam Banks and initially published by Fandom Tabletop, then acquired by Dire Wolf Digital. Prior versions appeared in the licensed roleplaying games published
Cortex_System
related species such as the dire wolf. 302M, a wolf featured in PBS and National Geographic documentaries 926F (Spitfire), a wolf popular with visitors of
List_of_individual_wolves
2025 live album and box set by Grateful Dead
McKernan, Weir, Hunter) – 20:59 Fillmore West – June 7, 1969 – selections: "Dire Wolf" (Garcia, Hunter) – 4:30 "Dupree's Diamond Blues" (Garcia, Hunter) – 4:36
Enjoying_the_Ride
Process of producing individual organisms with identical genomes
to Have Brought Back the Dire Wolf". Wired. Retrieved 12 August 2025. Jacobs, Phie (18 April 2025). "What's the deal with dire wolves? Iconic predators
Cloning
Extinction of large animals at the end of the last Ice Age
Caniformia Canidae Dire wolf (Aenocyon dirus) (C) Pleistocene coyote (Canis latrans orcutti) (C) Megafaunal wolf e.g. Beringian wolf (Canis lupus ssp.)
Late_Pleistocene_extinctions
1987 single by the Grateful Dead
Garcia Robert Hunter Producer John Cutler Grateful Dead singles chronology "Dire Wolf" (1981) "Touch of Grey" (1987) "When Push Comes to Shove" (1987)
Touch_of_Grey
Subspecies of gray wolf
and fossil North American wolves. The major limb bones of the dire wolf, Beringian wolf, and most modern North American gray wolves can be clearly distinguished
Great_Plains_wolf
is a large, silver dire wolf who was born with a splayed paw that has a swirling symbol representing a gyre soul. As a gnaw wolf, he was a member of
List of Guardians of Ga'Hoole characters
List_of_Guardians_of_Ga'Hoole_characters
1995 video game
the player is made a "21-star general" and transported to the E.S.S. Dire Wolf, where they meet the ship's Flexible Interactive Digital Omnicomputer
Big_Sky_Trooper
eldest son of Eddard and Catelyn Stark and the heir to Winterfell. His dire wolf is called Grey Wind. Robb becomes involved in the war against the Lannisters
List of Game of Thrones characters
List_of_Game_of_Thrones_characters
Amateur radio data communications protocol
only known complete implementation of v2.2, at this time (2020), is the Dire Wolf software terminal node controller (TNC). AX.25 is commonly used as the
AX.25
Extinct lineage of the grey wolf
Eastern Asia. Italian wolf, one of the last remaining mDNA haplogroup 2 grey wolves. Subspecies of Canis lupus Pleistocene coyote Dire wolf For a full set of
Pleistocene_wolf
Calendar year
wolves that are genetically modified to exhibit the characteristics of the dire wolf. April 8 – During a concert performance by Rubby Pérez in Santo Domingo
2025
Topics referred to by the same term
of North America Coywolf, a wolf-coyote hybrid Dire wolf (Aenocyon dirus), extinct canine of North America Edward's wolf (Canis edwardii), extinct canine
Wolf_(disambiguation)
Novel series by Kathryn Lasky
rogue dire wolves (or outclanners) led by the evil yellow dire wolf Heep. Faolan and Edme also discover that they are reincarnations of two great dire wolves
Guardians_of_Ga'Hoole
2011 online video game
a 2011 video game based on the Pokémon Trading Card Game developed by Dire Wolf Digital, a studio based in Denver, Colorado. The game was available for
Pokémon_TCG_Online
(2020): Dire Wolf Dune: House Secrets (2021); Portal Games Arrakis: Dawn of the Fremen (2022); Gale Force Nine Dune: Imperium - Uprising (2023): Dire Wolf Dune:
List_of_games_based_on_Dune
Bulgarian video game artist (1972–2025)
MachineGames' Wolfenstein: The New Order (2014); a visual designer of Dire Wolf Digital's The Elder Scrolls: Legends (2017); and a consultant on Bethesda
Viktor_Antonov_(artist)
American Magic: The Gathering player
Magic: The Gathering Pro Tour player and a game designer for Eternal at Dire Wolf Digital. Chapin has made six Pro Tour top eights, spanning three decades
Patrick_Chapin
Asphalt pit or asphalt lake
The most frequent large mammal found in the La Brea Tar Pits is the dire wolf, one of the most famous prehistoric carnivores that lived during the Pleistocene
Tar_pit
American science fiction drama television series
Castillo, a former runaway whose supposed father, Aaron, died after a dire wolf mauled him. It is later revealed that he kidnapped her when she was a
La_Brea_(TV_series)
National park in New Mexico, United States
lakebed that appeared to be footprints. During the 2010s, footprints of a dire wolf were discovered beside ancient seeds dated to more than 18,000 years ago
White_Sands_National_Park
Extinct subspecies of grey wolf
hybridisation between another grey wolf subspecies and the dire wolf. However, a 2021 study suggested reproductive isolation prevented dire wolves to hybridise with
Canis_lupus_furlongi
Hunting until the prey animal can no longer flee
endurance hunting in extinct species, though potential candidates include the dire wolf Aenocyon dirus due to its similar body shape to modern grey wolves. Non-avian
Persistence_hunting
2026 Japanese animated fantasy film
hobgoblin servants. Ranga Chikahiro Kobayashi Tyson Rinehart Ranga is a dire wolf serving Rimuru. Treyni Rie Tanaka Jamie Marchi The leader of the dryads
That Time I Got Reincarnated as a Slime the Movie: Tears of the Azure Sea
That_Time_I_Got_Reincarnated_as_a_Slime_the_Movie:_Tears_of_the_Azure_Sea
American singer-songwriter and musician
with Lenny Macaluso on an 80s-style rock anthem titled "Happy Birthday Dire Wolf" to celebrate the first birthday of the male wolves created by Colossal
Stan_Bush
2024 live album and box set by Grateful Dead
Robert Hunter) – 7:18 "Good Lovin'" (Rudy Clark, Arthur Resnick) – 6:24 "Dire Wolf" (Garcia, Hunter) – 4:38 "Me and My Uncle" > (John Phillips) – 3:08 "Big
Friend of the Devils: April 1978
Friend_of_the_Devils:_April_1978
Robert K.; Larson, Greger; Cooper, Alan; Frantz, Laurent A. F. (2021). "Dire wolves were the last of an ancient New World canid lineage". Nature. 591
Paleobiota of the La Brea Tar Pits
Paleobiota_of_the_La_Brea_Tar_Pits
British actor (born 1959)
Nightmare City 2035 Alex McDowell Cry of the Winged Serpent Griffin 2009 Dire Wolf Sheriff Parker 2013 The Right Regrets Chris Wickham Short film 2015 Those
Maxwell_Caulfield
2021 zoo-building board game by Mathias Wigge
published Ark Nova: Marine Worlds, an expansion for the base game, and Dire Wolf Digital released Ark Nova Digital as a cross-platform adaptation in 2025
Ark_Nova
Dice-drafting board game
Facades were released between 2019 and 2022. A digital version developed by Dire Wolf Digital was published as an app in 2020. In 2023, a legacy edition of
Sagrada_(board_game)
American actor (1943–2025)
Cabin Massacre! Narrator (voice) Short film 2009 Dire Wolf Col. Hendry Alternative title: Dino Wolf 2012 Blood Fare Professor Meade 2014 Boldly Gone Ben
Gil_Gerard
2018 board game
revised forest and event cards. A video game adaptation developed by Dire Wolf Digital was released in July 2022 on Steam, iOS and Android. A Nintendo
Everdell
1980 song by the Grateful Dead
Lovelight" "Death Don't Have No Mercy" Workingman's Dead "Uncle John's Band" "Dire Wolf" "New Speedway Boogie" "Cumberland Blues" "Black Peter" "Casey Jones"
Althea_(song)
British musician (born 1948)
other local bands including the Don King Blues Band, the Senders, the Dire Wolf Band, and was also the drummer for the Ruth Adams Polka Band for a short
Brian_Glascock
Paleontological research site in Los Angeles
Retrieved May 9, 2021. Ojibwa (December 13, 2017). "Paleontology 101: The Dire Wolf". Daily Kos. Kos Media, LLC. Retrieved May 9, 2021. Udurawane, Vasika;
La_Brea_Tar_Pits
World's Most Influential People May 12 Remus (dire wolf) (Asia) Extinct This is Remus. He's a dire wolf. The first to exist in over 10,000 years. Endangered
List of covers of Time magazine (2020s)
List_of_covers_of_Time_magazine_(2020s)
Extinct genus of carnivores
ensenadensis Canina (wolf-like canids) see below↓ Canina (wolf-like canids) Canina †Dire wolf (Aenocyon) †Sardinian dhole (Cynotherium) †Trinil dog (Mececyon)
Mesocyon
2026 American documentary series
ice age. A hibernating short-faced bear (Arctodus) awakens to drive a dire wolf away from her den and cubs. The following spring, mammoths and mastodons
Surviving_Earth
Fauna of the US state of Florida
or extirpated; such as the Florida short-faced bear, Florida black wolf, Dire wolf, Dexteria floridana, Florida bog lemming, Long-nosed peccary, Caribbean
Fauna_of_Florida
form, he wields the Authorise Buster. Lone Wolf (ローンウルフ, Rōn Urufu): A special form accessed from the Dire Wolf (ダイアウルフ, Daia Urufu) Zetsumerise Key combined
List of Kamen Rider Zero-One characters
List_of_Kamen_Rider_Zero-One_characters
Extinct genus of carnivores
ensenadensis Canina (wolf-like canids) see below↓ Canina (wolf-like canids) Canina †Dire wolf (Aenocyon) †Sardinian dhole (Cynotherium) †Trinil dog (Mececyon)
Archaeocyon
American Magic: The Gathering player
but ended his tenure as editor in 2012 to work as a game designer at Dire Wolf Digital, specifically on Eternal, and in 2021 LSV joined Good Luck Games
Luis_Scott-Vargas
2016 video game
inventory UI audio and block sound pickup/place, blood splatter on bear/dire wolf, prefab editor improvements, Twitch menu enhancements, AI investigation/range
7_Days_to_Die
PlayStation 4 Xbox One The Elder Scrolls: Legends Windows March 9, 2017 Dire Wolf Digital (2017–2018) Sparkypants Studios (2018–) macOS May 31, 2017 iOS
List of Bethesda Softworks video games
List_of_Bethesda_Softworks_video_games
Extinct Ice-Age European subspecies of wolf
domestic dog C. l. familiaris descended from these extinct lineages. Dire wolf Kempe, Stephan; Döppes, Doris (2009). "Cave Bear, Cave Lion and Cave Hyena
Cave_wolf
2017 free-to-play digital collectible card video game
gain as rewards. The Elder Scrolls: Legends was initially developed by Dire Wolf Digital. The game was revealed at Bethesda's 2015 Electronic Entertainment
The_Elder_Scrolls:_Legends
2022 studio album by Molly Tuttle
released on December 2, 2022, featured four bonus tracks - a cover of "Dire Wolf" by Grateful Dead, a rendition of the traditional folk song "Cold Rain
Crooked_Tree_(album)
1st episode of the 1st season of Game of Thrones
double. In the scene in which the Starks encounter a stag killed by a dire wolf as they return from the execution, an actual animal was used rather than
Winter_Is_Coming
2016 video game
Unlike previous games, there is prehistoric wildlife such as woolly mammoths, dire wolves, cave bears, cave lions, woolly rhinos, brontotherium, Irish elk and
Far_Cry_Primal
American geneticist (born 1954)
live birth of two "dire wolves" where gray wolf cells received 20 unique gene edits, including 15 edits that directly matched dire wolf DNA and notably an
George_Church_(geneticist)
1975 song by Grateful Dead
Lovelight" "Death Don't Have No Mercy" Workingman's Dead "Uncle John's Band" "Dire Wolf" "New Speedway Boogie" "Cumberland Blues" "Black Peter" "Casey Jones"
Crazy_Fingers
Fossil site in San Diego County, California
phalanx bones, 2 sesamoids and over 300 other bone fragments. Remains of dire wolf, horse, camel, mammoth and ground sloth were also found. Five cobbles
Cerutti_Mastodon_site
Canadian-British professor of genetics
Family Secrets". BBC. Retrieved 1 August 2024. "Hitler's DNA and the dire wolf". Chemical & Engineering News. 25 November 2025. Retrieved 27 November
Turi_King
January 24, 2025 The Elder Scrolls: Legends WIN, OSX, iOS, DROID DCCG Dire Wolf Digital, Sparkypants Studios Bethesda Softworks January 30, 2025 EA Sports
2025_in_video_games
Lyricist and member of the Grateful Dead (1941–2019)
influence of LSD, and by other hallucinatory experiences: Hunter wrote "Dire Wolf" inspired by a dream after watching a film adaptation of The Hound of
Robert_Hunter_(lyricist)
Extinct species of carnivore
greater intelligence. But the abundance of the seemingly intelligent dire wolf at the tar pits calls this hypothesis into question. Despite its rarity
American_lion
Tribe of carnivores
; Pollinger, J.P.; et al. (2009). "Evolutionary history of the Falklands wolf". Current Biology. 19 (20): R937–R938. Bibcode:2009CBio...19.R937S. doi:10
Canini_(tribe)
1993 American TV series or program
leader of a menacing pack of bumbling dire wolves. He uses threats to scare his minions into doing a good job. The dire wolves are one of two antagonists
Cro_(TV_series)
Species in mammal family Canidae
as wolfdogs or coywolves) or extinct prehistoric species (such as the dire wolf or Epicyon). Modern molecular studies indicate that the 13 genera can
List_of_canids
2002 studio album by the Tragically Hip
3:56 6. "Throwing off Glass" 3:28 7. "All Tore Up" 3:33 8. "Leave" 3:59 9. "A Beautiful Thing" 3:33 10. "The Dire Wolf" 4:29 11. "The Dark Canuck" 6:24
In_Violet_Light
2004 video game
and after reaching level 100 in World of Warcraft receive an Ironside Dire Wolf mount in Heroes of the Storm. Starting on March 11, 2016, players who
World_of_Warcraft
1976 single by Grateful Dead
Lovelight" "Death Don't Have No Mercy" Workingman's Dead "Uncle John's Band" "Dire Wolf" "New Speedway Boogie" "Cumberland Blues" "Black Peter" "Casey Jones"
Franklin's_Tower_(song)
1996 live album by Grateful Dead
(electric): "China Cat Sunflower" → "I Know You Rider", "Me and My Uncle", "Dire Wolf", "Smokestack Lightning"[b] Second set (acoustic): "The Monkey and the
Dick's_Picks_Volume_4
American comic book publisher
First Ghost #1– Jean Genie #1– Radioactive Revolution #1– Rook: Wardens – Dire Wolf #1– The Soulless: A Hyde Street Story #1– Gustines, George Gene (October
Ghost_Machine_(company)
Card game where each player creates a deck for their use
(Cryptozoic, 2020) Dominion (Rio Grande Games, 2008) Dune: Imperium (Dire Wolf Games, 2020) Eschaton (Archon Games, 2016) Forever Evil (Cryptozoic, 2014)
Deck-building_game
1970 single by Grateful Dead
Lovelight" "Death Don't Have No Mercy" Workingman's Dead "Uncle John's Band" "Dire Wolf" "New Speedway Boogie" "Cumberland Blues" "Black Peter" "Casey Jones"
Ripple_(song)
travel, tourism, insurance
DIRE WOLF
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travel, tourism, insurance