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Mammalian protein found in humans
Desmin is a protein that in humans is encoded by the DES gene. Desmin is a muscle-specific, type III intermediate filament that integrates the sarcolemma
Desmin
American actor (born 1983/1984)
Desmin Borges (born 1983/1984) is an American actor. He is best known for playing Edgar Quintero on the FX/FXX comedy-drama You're the Worst. Borges grew
Desmin_Borges
Medical condition
Desmin-related myofibrillar myopathy, is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin
Desmin-related myofibrillar myopathy
Desmin-related_myofibrillar_myopathy
American comedy-drama television series
executive, as they attempt a relationship, along with their friends Edgar (Desmin Borges) and Lindsay (Kether Donohue). The series premiered on July 17, 2014
You're_the_Worst
2022 film by Jason Moore
Darcy and Jamie's father Callie Hernandez as Jamie Rivera, Darcy's sister Desmin Borges as Ricky Silver, Tom's friend D'Arcy Carden as Harriet, Robert's
Shotgun_Wedding_(2022_film)
Cytoskeletal structure
intermediate filament proteins, which may form homo- or heteropolymeric proteins. Desmin IFs are structural components of the sarcomeres in muscle cells and connect
Intermediate_filament
Medical condition
disease. Recently it has been shown, that mutations in the desmin DES gene could cause ACM. Desmin is an intermediate filament protein, which is linked to
Arrhythmogenic_cardiomyopathy
2018 film by Tamara Jenkins
and Kathryn Hahn, with Kayli Carter, Molly Shannon, John Carroll Lynch, Desmin Borges, and Denis O'Hare in supporting roles. The film focuses on Richard
Private_Life_(2018_film)
Season of television series
Trina Brothers Jin Ha as Marshall P. Pope Siena Werber as Tawny Brothers Desmin Borges as Alfonso Richard Kind as Vince Fish Kumail Nanjiani as Rudy Thurber
Only Murders in the Building season 4
Only_Murders_in_the_Building_season_4
American television series (2021–present)
Trina's twin sister and the co-director of the film adaptation of the podcast Desmin Borges as Alfonso (season 4), the patriarch of a family living in the Arconia's
Only_Murders_in_the_Building
Network of filamentous proteins that forms the internal framework of cells
have been shown to cause serious medical issues such as premature aging, desmin mutations compromising organs, Alexander Disease, and muscular dystrophy
Cytoskeleton
American drama web television series
Kevin Christie Ashleigh LaThrop as Becky Todd Dan Byrd as Ian Ackerman Desmin Borges as Wilson Wilson Jessica Rothe as Samantha Christopher Denham as
Utopia_(2020_TV_series)
2022 American television mockumentary series
Binghoffer Jaime Pressly as Barb Flatch (season 2) William Tokarsky as Len Desmin Borges as Jimmy Jameson Jason MacDonald as Bobby Mallet Erin Bowles as Beth
Welcome_to_Flatch
2013 film by Henry Barrial
Bonilla in the title role, with Melissa Fumero, Saundra Santiago, Leo Minaya, Desmin Borges, John Herrera, Flor De Liz Perez, and Rosal Colon in supporting roles
The House That Jack Built (2013 film)
The_House_That_Jack_Built_(2013_film)
2025 American film
attention. Chase Stokes as Edward Brockman Lana Condor as Stephanie Selby Desmin Borges as Josh Weaver Callan Mulvey as Chris Lebold Jonathan Whitesell as
Valiant_One
2022 science fiction romantic drama TV series
as Henry DeTamble Jason David as young Henry Brian Altemus as teen Henry Desmin Borges as Gomez Natasha Lopez as Charisse Michael Park as Philip Abshire
The Time Traveler's Wife (TV series)
The_Time_Traveler's_Wife_(TV_series)
British television series
producer and Paul Feig as director and executive producer. On 4 December 2020, Desmin Borges joined the cast in recurring role. On 30 December 2020, Jason MacDonald
This_Country
Topics referred to by the same term
paradigm, a paradigm in cognitive psychology for investigating false memories Desmin related myopathy, a subgroup of the myofibrillar myopathy diseases Detergent
DRM
2011 comedy film directed by Mark Waters
Mitchell as Mr. Yates Jeffrey Tambor as Mr. Gremmins David Krumholtz as Kent Desmin Borges as Daryl James Tupper as Rick Betsy Aidem as Tavern hostess Matthew
Mr._Popper's_Penguins_(film)
Canadian silver mining company operating in Mexico
control of Desmin, the owner/operator of La Encantada (Coahuila, Mexico) in a US$4.75 million deal (ownership of the mine was purchased through Desmin from
First_Majestic_Silver
American television comedy series
Jefferson Mingus Joy Osmanski as Winnie Hyde Wolé Parks as Keith Calhoun Desmin Borges as Derek Trey Gerrald as Kent Chris Perfetti as Cody the Intern Tia
Next_Caller_(TV_series)
Protein filaments of myofibrils in muscle cells
Research on desmin revealed that its presence increased greatly in a test group exposed to resistance training, while there was no evidence of desmin increase
Myofilament
Topics referred to by the same term
and the origin of the phrase "DES daughter" DES gene, which encodes the desmin protein Diffuse esophageal spasm, a disorder of the esophagus Dissociative
DES
Type III intermediate filament protein
to the other three non-epithelial type III IF family members, vimentin, desmin and peripherin, which are all involved in the structure and function of
Glial fibrillary acidic protein
Glial_fibrillary_acidic_protein
American actress
brieftake.com. Retrieved March 15, 2026. "'Utopia': Ashleigh LaThrop, Desmin Borges, Farrah Mackenzie & Christopher Denham Join Amazon Drama Series"
Ashleigh_LaThrop
2026 film by Ari Selinger
as John Finch Lois Smith as Trudie Ferreira Anna Chlumsky as Jess Finch Desmin Borges as Austin Imlay Matthew Maher as Milton Ferreira Glenn Fleshler as
On_the_End
Reduction of blood flow to the heart
is found in cardiac muscle; it is a 'cytolinker' that connects actin and desmin to facilitate cytoskeletal function and vesicular movement. The endocytic
Coronary_artery_disease
Protein found in humans
multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and
Synemin
Aggressive and rare cancer
coexpression including the epithelial marker cytokeratin, the mesenchymal markers desmin and vimentin, and the neuronal marker neuron-specific enolase. Thus, although
Desmoplastic small-round-cell tumor
Desmoplastic_small-round-cell_tumor
Medical condition
erbB-3 receptor Cathepsin D CA 27-29 hPG80 General histology Sarcoma Vimentin Carcinoma (epithelium) Cytokeratin Musculoskeletal Rhabdomyosarcoma Desmin
Germinoma
Medical condition
nodules are positive for CD10; leiomyomas are positive for caldesmon and desmin (and sometimes CD10). Complete surgical excision (usually hysterectomy)
Endometrial_stromal_nodule
Largest known protein in human muscles
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Titin
American comedy television series
an interior architect. Alia Shawkat as Maia, Miles's younger half-sister Desmin Borges as Dan, Miles's co-worker Karen Pittman as Lenore Pool, Miles's boss
Living_with_Yourself
One of two veinous trunks bringing deoxygenated blood back to the heart
Histology. New York: Springer. pp. 131–133. Sonavane, Sushilkumar K.; Milner, Desmin M.; Singh, Satinder P.; Abdel Aal, Ahmed Kamel; Shahir, Kaushik S.; Chaturvedi
Superior_vena_cava
Genus of fishes in South America
muscle cells, the electric eel's electrocytes contain the proteins actin and desmin, but where muscle cell proteins form a dense structure of parallel fibrils
Electric_eel
Protein complex
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Troponin
Motor protein found in humans
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
KIF26A
Protein found in Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Filaggrin
Myxoid tumor of primitive connective tissue
variant has strands of collagen Vimentin; variable staining with actin, desmin, CD34 None Juxta-articular myxoma Poorly circumscribed infiltrates surrounding
Myxoma
2018 heist film directed by Steve McQueen
2017. N'Duka, Amanda (May 8, 2017). "Manuel Garcia-Rulfo Cast In 'Widows'; Desmin Borges Joins Netflix Film 'Private Life'". Deadline Hollywood. Archived
Widows_(2018_film)
Tumour-promoting cell type
Price TJ, Izwan Z, Hardi G, Cummins AG, Hardingham JE (December 2011). "Desmin expression in colorectal cancer stroma correlates with advanced stage disease
Cancer-associated_fibroblast
Congenital disease of heart muscle
combination with 1q21.1 deletion Syndrome. Furthermore, mutations in DES (desmin), TTN (titin), RBM20 and LMNA could be detected in a large cohort of LVNC
Noncompaction_cardiomyopathy
Medical condition
muscle markers (muscle specific actin MSA, smooth muscle actin SMA and desmin) positive in areas of smooth muscle differentiation CD117- (c-kit -) h-caldesmon-
Endometrial_stromal_sarcoma
Type IV intermediate filaments found in the cytoplasm of neurons
which are expressed in epithelia. Type III contains the proteins vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP). Type IV consists
Neurofilament
Surname list
Uruguayan footballer Celso Borges (born 1988), Costa Rican footballer Desmin Borges, American actor Fernanda Borges (born 1969), East Timorese politician
Borges_(surname)
Cell type
typically cover 30% of glomerular capillaries. They are both vimentin and desmin positive. There are five known functions of intraglomerular mesangial cells:
Intraglomerular mesangial cell
Intraglomerular_mesangial_cell
British television crime drama series (1983–1985)
2017. N'Duka, Amanda (8 May 2017). "Manuel Garcia-Rulfo Cast In 'Widows'; Desmin Borges Joins Netflix Film 'Private Life'". Deadline Hollywood. Retrieved
Widows_(TV_series)
Medical condition
and vimentin proteins but generally do not express CD34, S-100 protein, desmin, trypsin, factor VIII, F4/80, or HLA-DR1 proteins. Uncommonly, the cells
Nodular_fasciitis
Medical condition
membrane antigen, and CD34, whereas they are usually negative for S100, desmin, and FLI1 (FLI-1). They characteristically lack the protein INI1 (see below)
Epithelioid_sarcoma
Protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Spastin
(director/screenplay); Eric Tipton (screenplay); Chase Stokes, Lana Condor, Desmin Borges, Callan Mulvey, Jonathan Whitesell, Daniel Jun Love Me Bleecker Street
List of American films of 2025
List_of_American_films_of_2025
Structural fibrous protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Keratin
Inherited genetic condition resulting in muscle weakness
muscle, bone, and/or the central nervous system. The condition now called Desmin-related myofibrillar myopathy (also called myofibrillar myopathy-1) was
Hereditary inclusion body myopathy
Hereditary_inclusion_body_myopathy
2016 film by Susan Johnson
O'Donoghue as David Harrison William Moseley as Cy Jason Ritter as Matt Desmin Borges as Douglas Poorna Jagannathan as Fliss Nathan Lane as Dr. Petrov
Carrie_Pilby_(film)
Medical condition
diseases, non-infiltrative, and endomyocardial etiologies: Genetic DES (desmin) CRYAB (alpha B Crystallin, HSPB5) FLNC (filamin C) Infiltrative Amyloidosis
Restrictive_cardiomyopathy
Dermochondrocorneal dystrophy of François Dermoodontodysplasia Desbuquois syndrome Desmin-related myofibrillar myopathy Desmoid disease Desmoid tumor Desmoplastic
List_of_diseases_(D)
Cell type with functions of both muscular and fibrous connective tissue
muscle markers, such as intermediate filament type desmin in some tissues, but may be negative for desmin in other tissues. Similar heterogeneous positivity
Myofibroblast
are located; and their function. Most also express common markers such as desmin, laminin, various subunits of integrins, vascular cell adhesion molecule
Lymph_node_stromal_cell
List of notable individuals of Puerto Rican descent
Boneta (born 1990), actor, singer-songwriter (Puerto Rican grandfather) Desmin Borges, actor Lucy Boscana (1915–2001), television and theatrical actress
List_of_Puerto_Ricans
2009 dramatic comedy play by Kristoffer Diaz
starring Usman Ally (Vigneshwar Paduar), Kamal Angelo Bolden (Chad Deity), Desmin Borges (Macedonio Guerra), Jim Krag (Everett K. Olson), and Christian Litke
The Elaborate Entrance of Chad Deity
The_Elaborate_Entrance_of_Chad_Deity
2023 American film
Robinson as Hannah Kausar Mohammed as Esther Brandon Mychal Smith as Kaelin Desmin Borges as Cristean Emily Hampshire as Claudia Deborah Rennard as Stacy Pat
Appendage_(film)
Rod-shaped cytoplasmic protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Dystrophin
Mammalian protein
partner of desmin. These binding partners suggest that syncoilin acts as a mechanical "linker" between the sarcomere Z-disk (where desmin is localized)
Syncoilin
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Tubulin_alpha-1A_chain
Condition involving an enlarged, ineffective heart
changes. Other cytoskeletal proteins involved in DCM include α-cardiac actin, desmin, and the nuclear lamins A and C. Mitochondrial deletions and mutations presumably
Dilated_cardiomyopathy
Tumors originating from fibroblast or muscle cell precursors
they express smooth muscle marker proteins such as smooth muscle actins, desmin, and caldesmon. The World Health Organization further classified FMTs into
Fibroblastic and myofibroblastic tumors
Fibroblastic_and_myofibroblastic_tumors
Smooth muscle cell found in testis
distinctions between these layers. The inner layers have been shown to express desmin, a smooth muscle phenotype, whereas the outer layers express vimentin, a
Peritubular_myoid_cell
Microtubule-severing protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Katanin
Medical condition
Pleomorphic leimyosarcoma: Desmin and h-caldesmon (i.e. high molecular form of caldesmon.) proteins Pleomorphic rhabdomyosarcoma: Desmin and myogenin proteins
Undifferentiated pleomorphic sarcoma
Undifferentiated_pleomorphic_sarcoma
Medical condition
myopathy Type Eponym Inheritance OMIM Gene Locus Gene also implicated in: Desmin — adult onset (MFM1) Hereditary inclusion-body myositis type 1 AD αB-crystallin
Distal_myopathy
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
FLNC_(gene)
Involuntary non-striated muscle
also attach intermediate filaments (consisting largely of vimentin and desmin), and thereby appear to serve as anchors from which the thin filaments can
Smooth_muscle
Class of proteins
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Actin-binding_protein
Medical condition
and desmin protein-expressing cells in CAF help to distinguish it from myofibroblastoma. Unlike CAF, spindle cell lipomas seldom contain desmin protein-expressing
Cellular_angiofibroma
Protein-coding gene in the species Homo sapiens
Martin JJ, Goebel HH, Richard P, Guicheney P, Bönnemann CG (May 2004). "Desmin-related myopathy with Mallory body-like inclusions is caused by mutations
SELENON
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
MYL3
Component of striated muscle cells
to the extracellular connective tissue as some experiments have shown. Desmin protein may also bind to the DAG complex, and regions of it are known to
Costamere
Muscle enzyme involved in glycogen breakdown
weakness and muscle biopsy shows accumulation of the intermediate filament desmin in the myofibers. Unlike McArdle disease (GSD-V, myophosphorylase deficiency)
Myophosphorylase
Human chromosome
COL4A4: collagen, type IV, alpha 4 COL5A2: collagen, type V, alpha 2 DES: Desmin protein DIS3L2: DIS3 mitotic control homolog-like 2 ECEL1: Endothelin converting
Chromosome_2
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
KRT23
Protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Tropomyosin
Childhood soft-tissue cancer in mucosa-lined organs
vaginal epithelium (cambium layer). Spindle-shaped tumor cells that are desmin positive.[citation needed] The disease used to be uniformly fatal, with
Sarcoma_botryoides
Protein-coding gene in the species Homo sapiens
motifs is similar to other type III intermediate filament proteins such as desmin, vimentin and glial fibrillary acidic protein. Like these proteins, peripherin
Peripherin
Protein-coding gene in the species Homo sapiens
sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin". Am. J. Pathol. 142 (1): 221–30. PMC 1886840.
MYH13
Keratin protein in humans
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Keratin_18
Protein cytoskeletal component
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Tonofibril
Cell type found in certain tumors (rhabdomyosarcomas)
well. Immunohistochemistry techniques allow for the sensitive detection of desmin, vimentin, muscle specific actin, and MyoD1. Similarly the rhabdomyoblast
Rhabdomyoblast
Protein found in humans
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Keratin_2A
American award
Award: Bobby Steggert – Ragtime and Yank! Ellen Barkin – The Normal Heart Desmin Borges – The Elaborate Entrance of Chad Deity Halley Feiffer – The House
Theatre_World_Award
2014 American film
Louisa Krause as Sarah Alexia Rasmussen as Kelly Frank De Julio as Paul Desmin Borges as Rudy Seán Cullen as Jonathan Norton The film has an 84% rating
Gabriel_(2014_film)
Protein found in humans
cardiomyocytes, desmoplakin forms desmosomal plaques with the intermediate filament desmin, whereas in endothelial cells cytokeratin type intermediate filaments are
Desmoplakin
Motor protein found in humans
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
KIF21B
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
TNNT1
Multiprotein complex that forms a point of contact or adhesion in animal cells
membrane of adjacent cells. Intermediate filaments composed of keratin or desmin are attached to membrane-associated attachment proteins that form a dense
Cell_junction
Eukaryotic motor protein
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
Kinesin
French researcher (1929–2024)
is credited with key descriptions in the field of cardiomyopathies with desmin overload, severe autosomal recessive myopathies in children with adhaline
Michel_Fardeau
Medical condition
infiltrate. Staining is positive for vimentin, negative for cytokeratin and desmin, and variable for CD34, Factor VIIIa, SMA, MSA and S-100. Clinically, it
Cutaneous_myxoma
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
KIF4A
Protein-coding gene in humans
neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Although not yet clearly understood, defective chaperone
CRYAB
Protein-coding gene in the species Homo sapiens
chromosome 12 71 72 73 74 75 76 77 78 79 80 Not alpha Beta-keratin Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM
KRT81
DESMIN
DESMIN
DESMIN
DESMIN
Boy/Male
Hindu
Gift of Goddess
Female
English
(Δάφνη) Greek name DAPHNE means "laurel." In mythology, this is the name of a nymph who was turned into a laurel tree by her father so that she might escape Apollo's unwanted attentions.
Surname or Lastname
English and Welsh
English and Welsh : variant spelling of Glasscock.
Boy/Male
Tamil
Pradyun | பà¯à®°à®¤à®¯à¯à®¨
Radiant
Boy/Male
Muslim
Light bringer, Exalted high
Boy/Male
Tamil
Surname or Lastname
English
English : patronymic from Speak.
Girl/Female
Arabic, Muslim
Beautiful
Girl/Female
American, Australian, British, Chinese, English
Ash; Meadow of Ash Trees
Biblical
fear, or throwing down, of Jehovah
DESMIN
DESMIN
DESMIN
DESMIN
DESMIN
n.
A common mineral of the zeolite family, a hydrous silicate of alumina and lime, usually occurring in sheaflike aggregations of crystals, also in radiated masses. It is of a white or yellowish color, with pearly luster on the cleavage surface. Called also desmine.
n.
Same as Stilbite. It commonly occurs in bundles or tufts of crystals.