Search references for CUL1. Phrases containing CUL1
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Protein-coding gene in humans
Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination
CUL1
Hydrophobic scaffold protein
complex. CUL1, 2, 3, 4A, 4B, 5 and 7 each form part of a multi-subunit ubiquitin complex. Cullin-RING ubiquitin ligases (CRLs), such as Cul1 (SCF) play
Cullin
Type of protein
is essential for the recognition and binding of F-box proteins. Cullin (CUL1) – Cullin forms the major structural scaffold of the SCF complex and links
SCF_complex
Protein-coding gene in the species Homo sapiens
regulation of protein turn-over. RBX1 has been shown to interact with: CAND1, CUL1, CUL2, CUL4A, CUL5 CUL7, DCUN1D1, and P70-S6 Kinase 1. GRCh38: Ensembl release
RBX1
British motorcycle racer
Husqvarna CUL1 9 CUL2 11 LYN1 8 LYN2 8 CAN1 4 CAN2 13 HAW1 3 HAW2 5 DES1 4 DES2 4 5th 241 KTM BLA1 4 BLA2 1 PRD1 19 PRD2 7 FOX1 5 FOX2 3 2018 MX2 KTM CUL1 9 CUL2
Todd_Kellett
American biochemist and structural biologist
Goldenberg, S.J., Cascio, T.C., Shumway, S.D. et al. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit
Ning_Zheng
Protein-coding gene in humans
humans is encoded by the CAND1 gene. CAND1 has been shown to interact with: CUL1, CUL2, CUL3, CUL4A, CUL4B, DCUN1D1, and RBX1. GRCh38: Ensembl release 89:
CAND1
Protein
(Skp1-Cullin-F-box protein complex). SCF complexes consist of four proteins: Rbx1, Cul1, Skp1, which are invariant among SCF complexes, and an F-box protein, which
Ubiquitin_ligase
Topics referred to by the same term
a telecommunications network Small carbonaceous fossil SCF-complex (Skp1/Cul1/F-box complex), a ubiquitin ligase Supercritical fluid Standard cubic foot
SCF
Auto racing season
Pos Driver CUL1 FRE CHA1 INDY ALT1 LAU1 ALT2 LAU2 SAL CHA2 CUL2 Pts 1 Peter DePaolo 2 1 5 1* 1 1 DNP 2 1* 15 9 3260 2 Tommy Milton 1* 2 3 5 3 7 3 16 1
1925 AAA Championship Car season
1925_AAA_Championship_Car_season
Protein-coding gene in the species Homo sapiens
the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a
BTRC_(gene)
Protein-coding gene in humans
PMID 11285227. Lyapina S, Cope G, Shevchenko A, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COPS7B
control protein 4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which acts as a mediator of ubiquitin
Cell division control protein 4
Cell_division_control_protein_4
Protein-coding gene in humans
C, Wolf DA, Wei N, Shevchenko A, Deshaies RJ (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COPS6
Regulatory protein found in most eukaryotic tissues
independently. By inhibition of the ligase activity (through the making of Cul1 dominant negative thus renders ubiquitination not to occur), increased reporter
Ubiquitin
Protein-coding gene in the species Homo sapiens
acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box
FBXO31
Protein-coding gene in the species Homo sapiens
transferase activity ubiquitin binding Cellular component cytoplasm Parkin-FBXW7-Cul1 ubiquitin ligase complex SCF ubiquitin ligase complex nucleoplasm nucleolus
FBXW7
Protein complexes which degrade ubiquitin-tagged proteins by proteolysis
anaphase promoting complex (APC), an E3 ubiquitin ligase. The APC and the Skp1/Cul1/F-box protein complex (SCF complex) are the two key regulators of cyclin
Proteasome
Protein-coding gene in the species Homo sapiens
chromosome 7. SKP1A has been shown to interact with: BTRC, CACYBP, CDCA3, CDK9, CUL1, FBXL3, FBXO4, FBXO5, FBXO7, FBXW2, FBXW7, and SKP2. GRCh38: Ensembl release
S-phase kinase-associated protein 1
S-phase_kinase-associated_protein_1
Protein-coding gene in the species Homo sapiens
the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in a
FBXW11
Protein-coding gene in the species Homo sapiens
has been shown to interact with: CCNA2, CDK2, CDKN1A CDKN1B CKS1B, CDT1, CUL1 E2F1, ORC1L, and SKP1A. GRCh38: Ensembl release 89: ENSG00000145604 – Ensembl
SKP2
Protein-coding gene in the species Homo sapiens
603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called
SENP8
Protein-coding gene in the species Homo sapiens
acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box
FBXW10
Protein found in the human body
al., the best-characterized activated-NEDD8 substrates are the cullins (CUL1, 2, 3, 4A, 4B, 5, and 7 and PARC in human cells), that serve as molecular
NEDD8
Protein-coding gene in the species Homo sapiens
acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box
FBXO28
Protein-coding gene in humans
Matsumoto T, Xiong Y (Dec 2002). "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Molecular Cell. 10
CUL4A
Protein-coding gene in the species Homo sapiens
"The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1". Mol
RNF7
Protein complex
promote gene expression (e.g. AURKA). During late S phase BMYB is degraded via CUL1 (SCF complex), while FOXM1 is degraded during mitosis by the APC/C. Near
DREAM_complex
Nuclear protein
repeat-containing protein 1/2 (β-TrCP1/2) F-box protein-containing SKP1/Cul1/F-box protein complex "Gene: wee1 / SPCC18B5.03". PomBase. Nurse P (December
Wee1
Mammalian protein found in humans
Parkin (ligase) has been shown to interact with: Alpha-synuclein, CASK, CUL1, FBXW7 and GPR37, HSPA1A, HSPA8, Multisynthetase complex auxiliary component
Parkin_(protein)
Mammalian protein found in Homo sapiens
other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated
UBR1
American biochemist and cell biologist
of predicted metalloprotease motif of Jab1/Csn5 in cleavage of NEDD8 from CUL1. Science 298, 608-611 Verma, R., Aravind L., Oania, R., McDonald, W.H., Yates
Raymond_J._Deshaies
Protein-coding gene in humans
Wei N, Sun H, Kobayashi R, Zhang H (2003). "CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex". Mol. Cell
CUL4B
Protein-coding gene in humans
Shevchenko A, Serino G, Tsuge T, Zhou C, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–1385.
COPS4
Protein-coding gene in the species Homo sapiens
PMID 11285227. Lyapina S, Cope G, Shevchenko A, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
GPS1
Protein-coding gene in humans
Shevchenko A, Serino G, Tsuge T, Zhou C, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COPS7A
Protein-coding gene in humans
H, Fukuda M (April 2001). "In vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3". FEBS Letters. 494 (3): 181–185. doi:10.1016/S0014-5793(01)02343-2
CUL3
Protein-coding gene in humans
Matsumoto T, Xiong Y (2003). "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Mol. Cell. 10 (6):
CUL5
Protein-coding gene in humans
C, Wolf DA, Wei N, Shevchenko A, Deshaies RJ (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
CUL2
Protein-coding gene in the species Homo sapiens
PMID 11285227. Lyapina S, Cope G, Shevchenko A, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COP9 signalosome complex subunit 3
COP9_signalosome_complex_subunit_3
Protein-coding gene in the species Homo sapiens
E2F1 promoter[PAX8] => E2F1 E2F1 has been shown to interact with: ARID3A, CUL1, Cyclin A1, Cyclin A2, GTF2H1, MDM4, NCOA6, NDN, NPDC1, PURA, PHB, RB1, UDG
E2F1
Protein-coding gene in the species Homo sapiens
acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box
F-box_protein_40
Protein-coding gene in the species Homo sapiens
domain of KCTD7. However, KCTD7 does not show any interaction cullin-1 (CUL1). Immunoprecipitation assays also shows that KCTD7 does not interact with
KCTD7
O60494 3780 CUEDC1 HGNC:31350; Q9NWM3 3781 CUEDC2 HGNC:28352; Q9H467 3782 CUL1 HGNC:2551; Q13616 3783 CUL2 HGNC:2552; Q13617 3784 CUL3 HGNC:2553; Q13618
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Protein-coding gene in the species Homo sapiens
subunits of a ubiquitin ligase complex called SKP1-CUL1-F-box-protein, which includes the proteins CUL1, SKP1, and RBX1. The FBXL3 protein plays a role in
FBXL3
Protein tandem repeat
SD, Garbutt KC, Liu J, Xiong Y, Zheng N (2004). "Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit
HEAT_repeat
Protein-coding gene in the species Homo sapiens
variants being determined. FBXO7 has been shown to interact with SKP1A, CUL1, CDK6, p27, PI31, Parkin, and PINK1. GRCh38: Ensembl release 89: ENSG00000100225
FBXO7
Protein-coding gene in humans
C, Wolf DA, Wei N, Shevchenko A, Deshaies RJ (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COPS2
Protein-coding gene in the species Homo sapiens
driver in cancer cells. DCUN1D1 has been shown to interact with: CAND1, CUL1, CUL2, CUL3 and RBX1. GRCh38: Ensembl release 89: ENSG00000043093 – Ensembl
DCUN1D1
Protein-coding gene in humans
Wu K, Chen A, Tan P, Pan ZQ (January 2002). "The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient
CDC34
Protein-coding gene in the species Homo sapiens
Shevchenko A, Serino G, Tsuge T, Zhou C, et al. (May 2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COP9 constitutive photomorphogenic homolog subunit 5
COP9_constitutive_photomorphogenic_homolog_subunit_5
Protein-coding gene in the species Homo sapiens
Allen A, Rinehart CA, Yuan GC, Dutta A, Whetstine JR (Sep 2011). "The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates
FBXL4
Protein-coding gene in humans
Shevchenko A, Serino G, Tsuge T, Zhou C, et al. (2001). "Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome". Science. 292 (5520): 1382–5. Bibcode:2001Sci
COPS8
Protein-coding gene in the species Homo sapiens
generates 2 transcript variants. FBXO4 has been shown to interact with: CUL1, and SKP1A. GRCh38: Ensembl release 89: ENSG00000151876 – Ensembl, May 2017
FBXO4
CUL1
CUL1
CUL1
CUL1
Girl/Female
Assamese, Hindu, Indian, Kannada, Marathi, Sanskrit, Sindhi, Telugu
Sacred; Having the Power of Om
Girl/Female
Biblical
Fasting, tribulation.
Surname or Lastname
French
French : from a Germanic personal name, Warinhari, composed of the elements war(in) ‘guard’ + hari, heri ‘army’.English : variant of Garner 1.This name was also brought to America by the Huguenots.
Girl/Female
Assamese, Hindu, Indian, Tamil
Restless; Moon
Boy/Male
Australian, Biblical, Christian, Hebrew
God is Great
Boy/Male
Tamil
Biboswan | பீபோஸà¯à®µà®¾à®¨
Sun God
Male
Arthurian
, le blanc (the white), a knight.
Girl/Female
Indian
Goodness
Girl/Female
Assamese, Hindu, Indian
Sun; Moon; Lord of Sun; Lord Shiva
Girl/Female
British, English
Scarlet
CUL1
CUL1
CUL1
CUL1
CUL1