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CONGENITAL ATHYMIA

  • Congenital athymia
  • Rare immune disorder where the thymus is missing at birth

    Congenital athymia is an extremely rare disorder marked by the absence of the thymus at birth. T cell maturation and selection depend on the thymus, and

    Congenital athymia

    Congenital athymia

    Congenital_athymia

  • Allogeneic processed thymus tissue
  • Thymus tissue medical therapy

    is a thymus tissue therapy used for the treatment of children with congenital athymia. It is administered via a one-time surgical procedure where the tissue

    Allogeneic processed thymus tissue

    Allogeneic_processed_thymus_tissue

  • RVT-802
  • Experimental allogeneic

    developed by Enzyvant Therapeutics Ireland Limited for the treatment of congenital athymia (absence of a thymus gland), especially in the context of DiGeorge

    RVT-802

    RVT-802

  • Priority review
  • US Food and Drug Administration drug review program

    2021. "FDA Approves Innovative Treatment for Pediatric Patients with Congenital Athymia". U.S. Food and Drug Administration (FDA) (Press release). October

    Priority review

    Priority_review

  • Regenerative medicine advanced therapy
  • Drug candidate designation in the United States

    thalassemia RVT-802 Enzyvant allogeneic cell therapy Thymus tissue Congenital athymia in DiGeorge syndrome ECT-001 ExCellThera allogeneic cell therapy Hematologic

    Regenerative medicine advanced therapy

    Regenerative_medicine_advanced_therapy

  • FOXN1
  • Protein-coding gene in humans

    presentation. Pathogenic mutations in the FOXN1 gene are associated with congenital athymia, an ultra-rare disorder where the thymus fails to develop. This leads

    FOXN1

    FOXN1

    FOXN1

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CONGENITAL ATHYMIA

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CONGENITAL ATHYMIA

  • Congenial
  • a.

    Partaking of the same nature; allied by natural characteristics; kindred; sympathetic.

  • Congenital
  • a.

    Existing at, or dating from, birth; pertaining to one from birth; born with one; connate; constitutional; natural; as, a congenital deformity. See Connate.

  • Kindly
  • n.

    Humane; congenial; sympathetic; hence, disposed to do good to; benevolent; gracious; kind; helpful; as, kindly affections, words, acts, etc.

  • Adnate
  • a.

    Grown to congenitally.

  • Clubfoot
  • n.

    A short, variously distorted foot; also, the deformity, usually congenital, which such a foot exhibits; talipes.

  • Associate
  • v. i.

    To unite in company; to keep company, implying intimacy; as, congenial minds are disposed to associate.

  • Congeniality
  • n.

    The state or quality of being congenial; natural affinity; adaptation; suitableness.

  • Congenite
  • a.

    Congenital; connate; inborn. See Congenital.

  • Connate
  • a.

    Congenital; existing from birth.

  • Cogenial
  • a.

    Congenial.

  • Congenialize
  • v. t.

    To make congenial.

  • Congenitally
  • dv.

    In a congenital manner.

  • Congenial
  • a.

    Naturally adapted; suited to the disposition.

  • Congenially
  • adv.

    In a congenial manner; as, congenially married or employed.

  • Mute
  • n.

    One who, from deafness, either congenital or from early life, is unable to use articulate language; a deaf-mute.

  • Incongenial
  • a.

    Not congenial; uncongenial.

  • Kindred
  • a.

    Related; congenial; of the like nature or properties; as, kindred souls; kindred skies; kindred propositions.

  • Ectopic
  • a.

    Out of place; congenitally displaced; as, an ectopic organ.

  • Kind
  • superl.

    Having feelings befitting our common nature; congenial; sympathetic; as, a kind man; a kind heart.