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Organic chemical
Columbamine is an isoquinoline alkaloid made up of four rings, two of which contain nitrogen. It is related to berberine but without its methylenedioxy
Columbamine
Class of enzymes
Columbamine oxidase (EC 1.21.3.2) is an enzyme that catalyzes the chemical reaction that converts the benzylisoquinoline alkaloid, columbamine, into berberine
Columbamine_oxidase
Enzyme
Columbamine O-methyltransferase (EC 2.1.1.118) is an enzyme that catalyzes the chemical reaction columbamine + SAM palmatine + SAH This
Columbamine O-methyltransferase
Columbamine_O-methyltransferase
Species of shrub
oxyacanthine, palmatine, berberrubine, lambertine, obamegine, aromoline, columbamine, berlambine, tejedine, berbidine, and berbamine. The fruits were found
Berberis_vulgaris
Species of flowering plant
plant from East Africa. It contains isoquinoline alkaloids, including columbamine and is used mainly as a bitter tonic especially in cases of anorexia
Jateorhiza_palmata
Species of plant
quaternary isoquinoline alkaloids, dehydrocorydalmine, jatrorrhizine, columbamine, and oxyberberine, have been isolated from the whole plant of Argemone
Argemone_mexicana
4′-O-methyltransferase EC 2.1.1.117: (S)-scoulerine 9-O-methyltransferase EC 2.1.1.118: columbamine O-methyltransferase EC 2.1.1.119: 10-hydroxydihydrosanguinarine 10-O-methyltransferase
List_of_EC_numbers_(EC_2)
Climbing plant
quaternary alkaloids, such as berberine, palmatine, magnoflorine and columbamine. The seeds deliver picrotoxin, a sesquiterpene, while the seed shells
Anamirta_cocculus
Species of shrub
Several species of Berberis contain alkaloids such as berberine, canadine, columbamine, corypalmine, jatrorrhizine, and palmatine. These alkaloids are all very
Berberis_koreana
Index of enzymes associated with the same name
O-methyltransferase Catechol O-methyltransferase Chlorophenol O-methyltransferase Columbamine O-methyltransferase Demethylmacrocin O-methyltransferase 3'-demethylstaurosporine
O-methyltransferase
Chemical compound
Alternatively, a methylation reaction catalysed by columbamine O-methyltransferase produces palmatine from columbamine. The methyl group comes from the cofactor
Palmatine
Chemical compound
"Natural protoberberine alkaloids from Enantia chlorantha, palmatine, columbamine and jatrorrhizine for thioacetamide-traumatized rat liver". Acta Anatomica
Jatrorrhizine
Type of enzyme
to columbamine; tetrahydropalmatine to palmatine, and tetrahydropapaverine to papaverine. (S)-isocorypalmine + H+ 2 O2 2 H2O2 columbamine Amann
Tetrahydroberberine_oxidase
18, cellobiose dehydrogenase (acceptor) EC 1.1.3.26: Now EC 1.21.3.2, columbamine oxidase EC 1.1.3.27: hydroxyphytanate oxidase EC 1.1.3.28: nucleoside
List_of_EC_numbers_(EC_1)
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