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Protein-coding gene in humans
tumor suppressor 2 (MTS-2) or p15INK4b is a protein that is encoded by the CDKN2B gene in humans. This gene lies adjacent to the tumor suppressor gene CDKN2A
CDKN2B
Non-coding RNA in humans
CDKN2B-AS, also known as ANRIL (antisense non-coding RNA in the INK4 locus) is a long non-coding RNA consisting of 19 exons, spanning 126.3kb in the genome
CDKN2BAS
Cell lineage used in cell cultures
interferon gene cluster and cyclin-dependent kinase inhibitors CDKN2A and CDKN2B in the genome. Although African green monkeys were previously classified
Vero_cell
Type of spinal cancer
detected in 100%, 67%, 33% and 0% of cases, respectively. The CDKN2A (p16) and CDKN2B (p15) loci on chromosome 9p21 are frequently deleted in chordomas Another
Chordoma
1951 mouse tumour still used in research
cancer genes including Kras, Nras, Trp53, Dcc, and Cacna1d. Cdkn2a and Cdkn2b are biallelically deleted from the genome. Five pathways (RTK/RAS, p53,
Lewis_lung_carcinoma
Protein which inhibits cyclin-dependent kinase
Target p16 CDKN2A Cyclin-dependent kinase 4, Cyclin-dependent kinase 6 p15 CDKN2B Cyclin-dependent kinase 4 p18 CDKN2C Cyclin-dependent kinase 4, Cyclin-dependent
Cyclin-dependent kinase inhibitor protein
Cyclin-dependent_kinase_inhibitor_protein
Single stranded RNA
Another example is silencing of a tumor suppressor gene p15INK4b, also called CDKN2B, in acute lymphoblastic leukemia and acute myeloid leukemia. The asRNA that
Antisense_RNA
Topics referred to by the same term
P15 may refer to: Aviatik P.15, a German reconnaissance biplane CDKN2B, a human protein Lippisch P.15, a German prototype aircraft MAB PA-15 pistol Nissan
P15
Human chromosome
CHMP5: Charged multivesicular body protein 5 CNTLN: centlein CDKN2BAS: CDKN2B antisense RNA 1 or antisense non-coding RNA in the INK4 locus (ANRIL) COL5A1:
Chromosome_9
(January 2011). Huret JL, Ohgami RS, Dal Cin P, Rivas JM, Dessen P (eds.). "CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4))". Atlas of genetics
INK4
Medical condition
deletions in the NF1 gene occur ~10% of MFS cases while mutations in the CDKN2A/CDKN2B and amplifications in the CDK6, CCND1, and MDM2 genes occur in rare MFS
Myxofibrosarcoma
Health issue in Japan
frequencies between these populations. Genes such as CDKAL1, IGF2BP2, CDKN2A/CDKN2B, HHEX, SLC30A8, and KCNJ11 have shown risk alleles persistent to white populations;
Diabetes_in_Japan
Cancer originating in lymph nodes
T-cells), CDKN2A (encoding p16INK4a and p14arf tumor suppressor proteins) or CDKN2B (encoding cyclin dependent kinase inhibitor 2B multiple tumor suppressor
Follicular_lymphoma
Protein-coding gene in the species Homo sapiens
BCL2L11. Data partially confirmed earlier results and showed that variants in CDKN2B-AS1, RP1, and HDAC9 could be genetic susceptibility factors for IA in a
HDAC9
Human protein
Cyclin-dependent kinase 4 has been shown to interact with: CDC37, CDKN1B, CDKN2B, CDKN2C, CEBPA, CCND1, CCND3, DBNL, MyoD, P16, PCNA, and SERTAD1. GRCh38:
Cyclin-dependent_kinase_4
Medical condition
disease: 1) mutations in NRAS, ASXL1, and TP53; 2) deletions of the CDKN2A-ARF-CDKN2B locus on the short arm of chromosome 9, CDKN1B locus on the short arm of
Blastic plasmacytoid dendritic cell neoplasm
Blastic_plasmacytoid_dendritic_cell_neoplasm
Medical condition
cells. Hypermethylated of the promoters for two tumor suppressor genes, CDKN2B and CDKN2A (11 and 44% of cases, respectively) stops the genes from expressing
Primary cutaneous diffuse large B-cell lymphoma, leg type
Primary_cutaneous_diffuse_large_B-cell_lymphoma,_leg_type
FTO, KCNJ11, NOTCH2, WFS1, IGF2BP2, SLC30A8, JAZF1, HHEX, DGKB, CDKN2A, CDKN2B, KCNQ1, HNF1A, HNF1B MC4R, GIPR, HNF4A, MTNR1B, PPARG, ZBED3, SLC30A8, CDKAL1
Genetic causes of type 2 diabetes
Genetic_causes_of_type_2_diabetes
Medical condition
kinase Inhibitor 2A, a protein that regulates cell proliferation and the CDKN2B gene which encodes multiple tumor suppressor 2, a protein that regulates
Monomorphic epitheliotropic intestinal T cell lymphoma
Monomorphic_epitheliotropic_intestinal_T_cell_lymphoma
Complication of celiac disease
chromosome 17; genomic alterations around the CDKN2A tumor suppressor and CDKN2B cell proliferation regulator at position p21.3 on chromosome 9 that result
Enteropathy-associated T-cell lymphoma
Enteropathy-associated_T-cell_lymphoma
Protein domain
BCL3; BCOR; BCORL1; BTBD11; CAMTA1; CAMTA2; CASKIN1; CASKIN2; CCM1; CDKN2A; CDKN2B; CDKN2C; CDKN2D; CENTB1; CENTB2; CENTB5; CENTG1; CENTG2; CENTG3; CLIP3;
Ankyrin_repeat
Substance or process that is indicative of the presence of cancer in the body
and ovarian cancer; abnormal methylation of tumor suppressor genes p16, CDKN2B, and p14ARF for brain cancer; hypermethylation of MYOD1, CDH1, and CDH13
Cancer_biomarker
Field of study in cancer research
epigenetically altered in sarcomas. These include APC, CDKN1A, CDKN2A, CDKN2B, Ezrin, FGFR1, GADD45A, MGMT, STK3, STK4, PTEN, RASSF1A, WIF1, as well as
Cancer_epigenetics
Protein-coding gene in humans
Moretti A, Basso G, Borriello A, Della Ragione F (1998). "Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma". Hepatology. 27 (4):
CDKN2C
Medical condition
NCBI". "TP53 tumor protein p53 [Homo sapiens (human)] - Gene - NCBI". "CDKN2B cyclin dependent kinase inhibitor 2B [Homo sapiens (human)] - Gene - NCBI"
In_situ_lymphoid_neoplasia
2676 CDKN2AIP HGNC:24325; Q9NXV6 2677 CDKN2AIPNL HGNC:30545; Q96HQ2 2678 CDKN2B HGNC:1788; P42772 2679 CDKN2C HGNC:1789; P42773 2680 CDKN2D HGNC:1790; P55273
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
CDKN2B
CDKN2B
CDKN2B
CDKN2B
Boy/Male
Anglo, Arabic, Australian, Christian, German, Hebrew
Home; Heads; Chief; Hot or Heat; Blackness
Girl/Female
Arabic, Hindu, Indian, Muslim, Tamil
Wish; Desire; Goddess Lakshmi
Boy/Male
Arabic
The Sun; A Planet
Boy/Male
Tamil
Of exalted victory
Boy/Male
Arabic, Muslim
Preserver of the Religion (Islam)
Boy/Male
Hindu
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil
Famous; Successful; Foster Mother of Lord Krishna
Boy/Male
Tamil
God gift, Inherent, Inscribed into something, Within something
Boy/Male
English American Shakespearean
From the farm near the moor.
Girl/Female
Arabic, German, Indian, Kurdish, Muslim, Parsi
Cute Like a Flower; A Flower; Sun Plant; Stone-crop
CDKN2B
CDKN2B
CDKN2B
CDKN2B
CDKN2B