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Protein-coding gene in humans
ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family. CBL-B functions as a negative regulator of T-cell
CBLB_(gene)
Topics referred to by the same term
CBLB may refer to: CBLB (gene) CBLB (AM), a radio retransmitter (1340 AM) licensed to serve Schreiber, Ontario, Canada This disambiguation page lists
CBLB
Human chromosome
cblB type MON2: encoding protein Protein MON2 homolog MUCL1: encoding protein Mucin-like protein 1 MYO1A: myosin IA NANOG: NK-2 type homeodomain gene
Chromosome_12
Protein-coding gene in the species Homo sapiens
methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. GRCh38: Ensembl
MMAB
Protein-coding gene in the species Homo sapiens
of genotype and biochemical data in 32 patients belonging to mut, cblA or cblB complementation group". J. Inherit. Metab. Dis. 31 (1): 55–66. doi:10
MMAA
Medical condition
isoleucine, threonine, methionine, and valine without causing an attack. CblA und cblB versions of methylmalonic acidemia are cobalamin-responsive.[citation needed]
Methylmalonic_acidemias
Psychoactive component of cannabis
Omburo SN, Soto-Fuentes W, He J, et al. (2009). "Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa".
Tetrahydrocannabinol
Protein-coding gene in the species Homo sapiens
to SHORT syndrome. PIK3R1 has been shown to interact with: ADAM12, BCAR1, CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2
PIK3R1
Transmembrane protein
factor receptor has been shown to interact with: AR, ARF4, CAV1, CAV3, CBL, CBLB, CBLC, CD44, CDC25A, CRK, CTNNB1, DCN, EGF, GRB14, Grb2, JAK2, MUC1, NCK1
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Protein family
BARD1, BBAP, BFAR, BIRC2, BIRC3, BIRC7, BIRC8, BMI1, BRAP, BRCA1, CBL, CBLB, CBLC, CBLL1, CHFR, CNOT4, COMMD3, DTX1, DTX2, DTX3, DTX3L, DTX4, DZIP3,
RING_finger_domain
Protein-coding gene in the species Homo sapiens
gene, Arachidonate 5-lipoxygenase, B-cell linker, BCAR1, BCR gene, Beta-2 adrenergic receptor, C-Met, CBLB, CD117, CD22, CD28, CDKN1B, CRK, Cbl gene,
GRB2
"Statistics & download files". www.genenames.org. HUGO Gene Nomenclature Committee. 3 November 2025. Retrieved 3 November 2025.
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Human protein encoding gene
enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB". PLOS Pathogens. 14 (7) e1007111. doi:10.1371/journal.ppat.1007111. PMC 6053247
C2orf72
Rare metabolic disease
disorder caused by homozygous or compound heterozygous variants in the ACSF3 gene. This results in a defect of the mitochondrial enzyme acyl-CoA synthetase
Combined malonic and methylmalonic aciduria
Combined_malonic_and_methylmalonic_aciduria
Form of cancer immunotherapy
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB, and CISH. More recently, CISH (cytokine-inducible SH2-containing protein)
Checkpoint_inhibitor
Protein-coding gene in humans
reported to be involved in activation of MAPK signaling. E3 ubiquitin ligase CBLB has been described as negative regulator of dectin-2. Dectin-2 is known to
CLEC6A
Protein-coding gene in the species Homo sapiens
SH3GLB2, SH3GL3, SH3GL2, BCAR1, Epidermal growth factor receptor, CBLB, Cbl gene, SOS1, CRK and PAK2. GRCh38: Ensembl release 89: ENSG00000147010 – Ensembl
SH3KBP1
Protein-coding gene in the species Homo sapiens
of DAB1. CRKL has been shown to interact with: Abl gene, BCAR1, BCR gene, CBLB, CD117, CD34, Cbl gene, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5,
CRKL
Protein-coding gene in the species Homo sapiens
enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB". PLOS Pathogens. 14 (7): 55–67. doi:10.1371/journal.ppat.1007111. PMC 6053247
APOL2
Psychoactive drug from the cannabis plant
Publishing. pp. 12. ISBN 978-1-878823-23-6. Richer, Alanna Durkin; Johnson, Gene (23 April 2026). "Trump reclassifies state-licensed medical marijuana as
Cannabis_(drug)
Phytocannabinoid discovered in 1940
Omburo SN, Soto-Fuentes W, He J, et al. (2009). "Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa".
Cannabidiol
Proposed mechanism of cannabis compounds
Dominik (2022). "Analysis of Morphological Traits, Cannabinoid Profiles, THCAS Gene Sequences, and Photosynthesis in Wide and Narrow Leaflet High-Cannabidiol
Entourage_effect
THC precursor
show a significant increased cytotoxic activity and suppress COX-2 and MMP9 gene expression in both cell culture and colon tissue, suggest the anti-inflammatory
Tetrahydrocannabinolic_acid
Medical therapy involving transplant of cells expanded ex vivo
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB. More recently, CISH, a molecule with ubiquitin ligase activity, was found
Adoptive_cell_transfer
Chemical compound (fatty acid neurotransmitter)
glutamatergic neurons independently of corticotropin-releasing hormone signaling". Genes, Brain and Behavior. 8 (2): 203–211. doi:10.1111/j.1601-183X.2008.00463
Anandamide
Chemical compound
It can increase the TRPV1-mediated release of substance P and calcitonin gene-related peptide (CGRP) in rat dorsal spinal cord slices. Furthermore, NADA
N-Arachidonoyl_dopamine
Artificial stimulation of the immune system to treat cancer
intrinsic regulators include molecules with ubiquitin ligase activity, including CBLB. More recently, CISH, a molecule with ubiquitin ligase activity, was found
Cancer_immunotherapy
Group of stereoisomers
suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression". PeerJ. 1: e214. doi:10.7717/peerj.214. PMC 3840466. PMID 24282673
Cannabidivarin
and psychosis, but that "more work is needed to address the possibility of gene-environment correlation." In 2016 a meta-analysis was published on associations
Long-term_effects_of_cannabis
Post-translational modifications involving the protein NEDD8
catalyzing non-cullin protein neddylation, as has recently been the case for CBLb-mediated neddylation of PARP-1. To date, notable non-cullin neddylation substrates
Neddylation
Endogenous neuropeptide found in mammalian brain
CBCA CBCA-A CBCB CBCBA CBCP CBCPA CBCV CBCVA CBCQ Cannabicyclols CBL CBLA CBLB CBLP CBLPA CBLV CBLVA Cannabidiols CBD CBDA CBD-C1 CBD-C5 CBDB CBDBA CBDD
RVD-Hpα
Chemical compound
Intolerance, Hepatic Steatosis, and Novel Cannabinoid Receptor 1 Responsive Genes". PLOS ONE. 6 (11) e26415. Bibcode:2011PLoSO...626415R. doi:10.1371/journal
IDFP
CBLB GENE
CBLB GENE
Female
Welsh
Medieval Welsh name, probably GENERYS means "white lady."Â
Female
English
 English form of French Geneviève, probably GENEVIEVE means "race of women."
Male
English
Short form of English Eugene, GENE means "well born."
Surname or Lastname
English and Scottish
English and Scottish : from the Middle English personal name Ma(t)thew, vernacular form of the Greek New Testament name Matthias, Matthaios, which is ultimately from the Hebrew personal name Matityahu ‘gift of God’. This was taken into Latin as Mat(t)hias and Matthaeus respectively, the former being used for the twelfth apostle (who replaced Judas Iscariot) and the latter for the author of the first Gospel. In many European languages this distinction is reflected in different surname forms. The commonest vernacular forms of the personal name, including English Matthew, Old French Matheu, Spanish Mateo, Italian Matteo, Portuguese Mateus, Catalan and Occitan Mateu are generally derived from the form Matthaeus. The American surname Matthew has also absorbed European cognates from other languages, including Greek Mathias and Mattheos.It is found as a personal name among Christians in India, and in the U.S. is used as a family name among families from southern India.
Female
English
(ΓÎνεσις) English name of Greek origin, derived from the word genesis, GENESIS means "creation, generation, origin, source," from gignesthai "to be born," which is related to genos "birth, descent, race." In the bible, this is the name of the first book of the Old Testament.
Surname or Lastname
English (Gloucestershire and South Wales)
English (Gloucestershire and South Wales) : most probably from the Norman personal name Luce (a vernacular form of Latin Lucia or Lucius). This is generally a female name, although male bearers are found in France. It was borne by a young Sicilian maiden and an aged Roman widow, both of whom were martyred under Diocletian and are venerated as saints.English (Gloucestershire and South Wales) : Alternatively, the surname may be a variant of Lewis.English (Gloucestershire and South Wales) : American bearers of this surname are descended from Henry Luce (1640–c.1688), who came to Scituate, MA, from south Wales in or before 1666, and moved to Martha’s Vineyard, MA, in about 1670. He had many prominent descendants.
Girl/Female
Australian, Spanish
Generous
Surname or Lastname
English (Bedfordshire)
English (Bedfordshire) : habitational name from an unidentified place. In Tudor records, the surname is generally spelled Logsden or Loggesden. It may be a variant of Loxton, name of a place in Somerset, or possibly an irregularly altered form of Roxton, name of a place in Bedfordshire (see Ruxton).A William Logsden is recorded in Somerset Co., MD, tax rolls in the late 17th century.
Surname or Lastname
Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29
Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29 : 16) + the Slavic possessive suffix -in.English : from a medieval personal name, a diminutive of Lawrence. Compare Law 1 and Larkin.
Surname or Lastname
English
English : topographic name from Middle English lang, long ‘long’ + strete ‘road’.Translation of Dutch Langestraet, cognate with 1.The confederate general James Longstreet (1821–1904), was born in SC, came from an old Dutch family in New Netherland with the name Langestraet; he was the nephew of Augustus B. Longstreet, a Methodist clergyman born in Augusta, GA, in 1790.
Surname or Lastname
English
English : habitational name from the city in West Yorkshire, or the place in Kent. The former is of British origin, appearing in Bede in the form Loidis ‘People of the LÄt’, (LÄt being an earlier name of the river Aire, meaning ‘the violent one’). Loidis was originally a district name, but was subsequently restricted to the city. The Kentish place name may be from an Old English stream name hlÌ„de ‘loud, rushing stream’.Daniel Leeds (1652–1720) was born in England, probably in Nottinghamshire, and emigrated to America with his father, Thomas, some time in the third quarter of the 17th century. The family settled in Shrewsbury, NJ, in 1677. Daniel made almanacs and was surveyor general of the Province of West Jersey in 1682. He was married four times and had numerous children.
Surname or Lastname
English
English : from the Middle English vernacular form, Maudeleyn, of the New Testament Greek personal name Magdalēnē. This is a byname, meaning ‘woman from Magdala’ (a village on the Sea of Galilee, deriving its name from Hebrew migdal ‘tower’), denoting the woman cured of evil spirits by Jesus (Luke 8:2), who later became a faithful follower. In Christian folk belief she was generally identified with the repentant sinner who washed Christ’s feet with her tears in Luke 7; hence the name came to be used as a byname for a prostitute, also a tearful woman. The popularity of the personal name increased with the supposed discovery of her relics in the 13th century.
Boy/Male
Spanish
Generous.
Female
English
Pet form of French Geneviève, probably GENEVA means "race of women."
Female
French
French form of Celtic Genovefa, probably GENEVIÈVE means "race of women."
Girl/Female
Australian, French, Italian
Italian Form of Genevieve; White Wave; Of the Race of Women; Fair and Yielding; Juniper Tree
Surname or Lastname
Scottish
Scottish : habitational name from Mar in Aberdeenshire, the etymology of which is uncertain, possibly Old Norse marr, a rare word generally denoting the sea, but perhaps also a marsh or fen, as reflected in modern dialect forms.English : habitational name from Marr in West Yorkshire, whose name is likewise of uncertain origin; possibly the same as 1.German : from the Germanic personal name Marro.
Female
Italian
Variant spelling of Italian Ginevra, probably GENEVRA means "race of women."
Female
English
English variant spelling of French Jeanette, GENETTE means "God is gracious."
Surname or Lastname
English
English : unexplained.John Mifflin (born 1640) came to Delaware from Warminster, Wiltshire, England, in the 1670s. He is probably the same person as the John Mifflin, a Quaker, who built his home, ‘Fountain Green’, in Fairmont Park, Philadelphia, in 1679. His fourth-generation descendant Thomas Mifflin (1744–1800) was a member of the Continental Congress, a revolutionary soldier, and governor of PA.
CBLB GENE
CBLB GENE
Boy/Male
Welsh
Legendary son of Deorthach.
Boy/Male
Hindu
Boy/Male
Indian, Sanskrit
Daughter of Mountains
Female
Finnish
Finnish form of Latin Dorothea, TEIJA means "gift of God."Â
Girl/Female
Tamil
Adrishya | அதà¯à®°à¯€à®·à¯à®¯
Perception
Boy/Male
Hawaiian
Worships well.
Male
Icelandic
Icelandic form of Old Norse Halfdanr, HÃLFDAN means "half Dane."
Girl/Female
British, Dutch, English, Hebrew
Variant of Maria; Bitterness
Boy/Male
Teutonic
Friend of the soil.
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
Lord Shiva
CBLB GENE
CBLB GENE
CBLB GENE
CBLB GENE
CBLB GENE
n.
Alt. of Genette
n. sing. & pl.
A native or inhabitant of Geneva; collectively, the inhabitants of Geneva; people of Geneva.
n.
The fur of the common genet (Genetta vulgaris); also, any skin dressed in imitation of this fur.
a.
Pertaining to, concerned with, or determined by, the genesis of anything, or its natural mode of production or development.
n.
A supported of Genevanism.
n.
A native or inhabitant of Geneva.
adv.
In a genetical manner.
n.
One skilled in genethliacs.
a.
Same as Genetical.
a.
Of or pertaining to Geneva, in Switzerland; Genevese.
pl.
of Postmaster-general
n.
The second law officer in the government of Great Britain; also, a similar officer under the United States government, who is associated with the attorney-general; also, the chief law officer of some of the States.
a.
Of or pertaining to Geneva, in Switzerland; Genevan.
a.
Genethliac.
n.
The chief officer of the post-office department of a government. In the United States the postmaster-general is a member of the cabinet.
n.
One of several species of small Carnivora of the genus Genetta, allied to the civets, but having the scent glands less developed, and without a pouch.