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C5A

  • Lockheed C-5 Galaxy
  • American heavy military transport aircraft

    The Lockheed C-5 Galaxy is a large military transport aircraft designed and built by Lockheed, and now maintained and upgraded by its successor, Lockheed

    Lockheed C-5 Galaxy

    Lockheed C-5 Galaxy

    Lockheed_C-5_Galaxy

  • C5a
  • Topics referred to by the same term

    C5a or C-5A may refer to: C5a receptor, a receptor for complement component 5a Complement component 5a, a human protein fragment, a chemotactic factor

    C5a

    C5a

  • C5a receptor
  • Mammalian protein found in Homo sapiens

    C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a

    C5a receptor

    C5a receptor

    C5a_receptor

  • Complement component 5a
  • Protein fragment

    C5a is a protein fragment released from cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late

    Complement component 5a

    Complement component 5a

    Complement_component_5a

  • Avacopan
  • Chemical compound

    October 2021. It is the first orally-administered inhibitor of the complement C5a receptor approved by the US Food and Drug Administration (FDA). The FDA considers

    Avacopan

    Avacopan

    Avacopan

  • Complement component 5
  • Protein found in humans

    component 5 is involved in the complement system. It is cleaved into C5a and C5b: C5a plays an important role in chemotaxis. C5b forms the first part of

    Complement component 5

    Complement component 5

    Complement_component_5

  • Vilobelimab
  • Medication

    COVID-19. It is a human-mouse chimeric IgG4 kappa antibody that targets human C5a in plasma. The most common adverse reactions include pneumonia, sepsis, delirium

    Vilobelimab

    Vilobelimab

  • Streptococcus pyogenes
  • Species of bacterium

    Cleary PP (December 1985). "Mechanism of action of the group A streptococcal C5a inactivator". Proceedings of the National Academy of Sciences of the United

    Streptococcus pyogenes

    Streptococcus pyogenes

    Streptococcus_pyogenes

  • Anaphylatoxin
  • Protein domain

    Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement

    Anaphylatoxin

    Anaphylatoxin

    Anaphylatoxin

  • Complement system
  • Part of the immune system that enhances the ability of antibodies and phagocytic cells

    which cleaves C5 into C5b and C5a. C5 convertase is also formed by the classical pathway when C3b binds C4b and C2b. C5a is an important chemotactic protein

    Complement system

    Complement system

    Complement_system

  • C3a (complement)
  • responses, its activity able to counteract the proinflammatory effects of C5a. Initial research in mice demonstrating an effective treatment after stroke

    C3a (complement)

    C3a (complement)

    C3a_(complement)

  • C5AR2
  • Protein-coding gene in the species Homo sapiens

    C5aR1 and C5aR2. The anaphylatoxin receptors are a family of three proteins which beloing to the G protein-coupled receptor superfamily. C3aR and C5aR1

    C5AR2

    C5AR2

    C5AR2

  • C5a peptidase
  • C5a peptidase (EC 3.4.21.110, streptococcal C5a peptidase, ScpA, ScpB, SCPA) is an enzyme. The primary cleavage site is at His67-Lys68 in human C5a with

    C5a peptidase

    C5a_peptidase

  • C5-convertase
  • Serine protease that plays key role in innate immunity

    different C5 convertases able to specifically convert the protein C5 to C5a and C5b fragments. Two of the convertases are physiological complement enzymes

    C5-convertase

    C5-convertase

    C5-convertase

  • Carboxypeptidase B
  • Class of enzymes

    carboxypeptidase B (carboxypeptidase B2) is responsible for converting the C5a protein into C5a des-Arg, with one less amino acid. Folk JE (1970). "Carboxypeptidase

    Carboxypeptidase B

    Carboxypeptidase B

    Carboxypeptidase_B

  • ATLAS-I
  • Cold War military equipment of the US

    Trestle facility under construction in 1975. The height of the termination tower was driven by the need to clear the tail of a C5A Galaxy transport.

    ATLAS-I

    ATLAS-I

    ATLAS-I

  • Zilucoplan
  • Chemical compound

    to the protein complement component 5 (C5) and inhibits its cleavage into C5a and C5b. Zilucoplan was approved for medical use in the United States in

    Zilucoplan

    Zilucoplan

    Zilucoplan

  • Neutrophil
  • Type of white blood cell

    interstitial space, following chemical signals such as interleukin-8 (IL-8), C5a, fMLP, leukotriene B4, and hydrogen peroxide (H2O2) in a process called chemotaxis

    Neutrophil

    Neutrophil

    Neutrophil

  • SCPA
  • Topics referred to by the same term

    Authority Space Canine Patrol Agents, fictional canine superheroes in DC Comics C5a peptidase, an enzyme S.C.p.A., or Società consortile per azioni, a type of

    SCPA

    SCPA

  • Classical complement pathway
  • Aspect of the immune system

    convertase then cleaves C5 into C5a and C5b. Like C3a, C5a is also an anaphylatoxin that interacts with its cognate C5a receptor (C5aR) to attract leukocytes

    Classical complement pathway

    Classical complement pathway

    Classical_complement_pathway

  • Acute hemolytic transfusion reaction
  • Complication of blood transfusion

    complement cascade via C3a and C5a, which then promote inflammatory cytokine release from white blood cells. C3a and C5a also activate mast cells which

    Acute hemolytic transfusion reaction

    Acute_hemolytic_transfusion_reaction

  • C3a receptor
  • Protein-coding gene in humans

    Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors". Pharmacological Reviews. 65 (1): 500–43. doi:10

    C3a receptor

    C3a receptor

    C3a_receptor

  • Leukocyte extravasation
  • Movement of white blood cells out of blood vessels and towards the inflamed site

    tissue release cytokines such as IL-1, TNFα and chemokines. IL-1, TNFα and C5a cause the endothelial cells of blood vessels near the site of infection to

    Leukocyte extravasation

    Leukocyte extravasation

    Leukocyte_extravasation

  • Inflammation
  • Physical effects resulting from activation of the immune system

    A variety of molecules behave as chemoattractants, for example, C3a or C5a (the anaphylatoxins), and cause the leukocytes to move along a chemotactic

    Inflammation

    Inflammation

    Inflammation

  • Eculizumab
  • Pharmaceutical drug

    impeded. Eculizumab inhibits the cleavage of C5 by the C5 convertase into C5a, a potent anaphylatoxin with prothrombotic and proinflammatory properties

    Eculizumab

    Eculizumab

  • Anaphylatoxin receptors
  • Group of G-protein coupled receptors

    bind anaphylatoxins. Members of this family include: C3a receptor C3AR1 C5a receptor C5AR1 C5L2 GPR77 Fukuoka Y, Nielsen LP, Hugli TE (1989). "Characterization

    Anaphylatoxin receptors

    Anaphylatoxin_receptors

  • Ventilator-associated pneumonia
  • Pneumonia due to use of ventilator

    with this impairment being driven by pro-inflammatory molecules such as C5a. These defects in immune function appear to be causally linked to the development

    Ventilator-associated pneumonia

    Ventilator-associated pneumonia

    Ventilator-associated_pneumonia

  • Hypersensitivity
  • Overreaction of the immune system to an antigen

    pathways as the expression of activating FcγRs is shown to be increased by C5a receptor signaling. Additionally, there are instances in which complement

    Hypersensitivity

    Hypersensitivity

    Hypersensitivity

  • Arthus reaction
  • Medical condition

    investigation demonstrated that complement, specifically the anaphylatoxin C5a, can drive the Arthus reaction indirectly because the resultant signaling

    Arthus reaction

    Arthus_reaction

  • Muscarinic acetylcholine receptor
  • Acetylcholine receptors named for their selective binding of muscarine

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Muscarinic acetylcholine receptor

    Muscarinic acetylcholine receptor

    Muscarinic_acetylcholine_receptor

  • Formyl peptide receptor 1
  • Protein-coding gene in the species Homo sapiens

    factor receptor, the C5a receptor (also termed CD88), which binds and is activated by complement component 5a (C5a) and GPR77, a second C5a anaphylatoxin chemotactic

    Formyl peptide receptor 1

    Formyl peptide receptor 1

    Formyl_peptide_receptor_1

  • Adrenergic receptor
  • Class of G protein-coupled receptors

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Adrenergic receptor

    Adrenergic receptor

    Adrenergic_receptor

  • C3b
  • Part of the innate immune system

    (C4b2b3b) results in the formation of a C5 convertase, which cleaves C5 into C5a and C5b. C5b associates with C6, C7, C8, and C9, all of which form a complex

    C3b

    C3b

    C3b

  • Complement membrane attack complex
  • Protein complex

    complex is initiated when the complement protein C5 convertase cleaves C5 into C5a and C5b. All three pathways of the complement system (classical, lectin and

    Complement membrane attack complex

    Complement membrane attack complex

    Complement_membrane_attack_complex

  • VN1R1
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    VN1R1

    VN1R1

    VN1R1

  • Glucagon receptor
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Glucagon receptor

    Glucagon receptor

    Glucagon_receptor

  • Complement receptor
  • Protein family

    activation C5AR1 C5a receptor 50,000 C5a CD88 Endo, MC, Pha Cell activation, immune polarization, chemotaxis C5AR2 C5a receptor 2 36,000 C5a – Chemotaxis

    Complement receptor

    Complement_receptor

  • G protein-coupled receptor
  • Class of cell surface receptors coupled to G-protein-associated intracellular signaling

    platelet-activating factor, and leukotrienes); peptide hormones (e.g., calcitonin, C5a anaphylatoxin, follicle-stimulating hormone [FSH], gonadotropin-releasing

    G protein-coupled receptor

    G protein-coupled receptor

    G_protein-coupled_receptor

  • Prokineticin receptor 1
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Prokineticin receptor 1

    Prokineticin receptor 1

    Prokineticin_receptor_1

  • GPR68
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR68

    GPR68

    GPR68

  • Tom Mollnes
  • Norwegian immunologist

    complement's significant role in inflammation and tissue damage, highlighting the C5a receptor's involvement in E. coli-induced oxidative burst and phagocytosis

    Tom Mollnes

    Tom_Mollnes

  • Alpha-2 adrenergic receptor
  • Protein family

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Alpha-2 adrenergic receptor

    Alpha-2 adrenergic receptor

    Alpha-2_adrenergic_receptor

  • Gonadotropin receptor
  • Class of receptors

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Gonadotropin receptor

    Gonadotropin_receptor

  • Cooper Hewitt, Smithsonian Design Museum
  • Design museum in Manhattan, New York

    "Cooper-Hewitt library is designers' treasure trove". The Hartford Courant. p. C5A. ISSN 1047-4153. ProQuest 1081195183. "Drue Heinz Study Center for Drawings

    Cooper Hewitt, Smithsonian Design Museum

    Cooper Hewitt, Smithsonian Design Museum

    Cooper_Hewitt,_Smithsonian_Design_Museum

  • CELSR3
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    CELSR3

    CELSR3

    CELSR3

  • Rhodopsin
  • Light-sensitive receptor protein

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Rhodopsin

    Rhodopsin

    Rhodopsin

  • Membrane estrogen receptor
  • Receptor group

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Membrane estrogen receptor

    Membrane estrogen receptor

    Membrane_estrogen_receptor

  • 1975
  • Calendar year

    cephe). April 4 Vietnam War: The first military Operation Babylift flight, C5A 80218, crashes 27 minutes after takeoff, killing 138 on board; 176 survive

    1975

    1975

  • Opioid receptor
  • Group of biological receptors

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Opioid receptor

    Opioid receptor

    Opioid_receptor

  • Adenosine A3 receptor
  • Cell surface receptor found in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Adenosine A3 receptor

    Adenosine A3 receptor

    Adenosine_A3_receptor

  • Neurotensin receptor
  • InterPro Family

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Neurotensin receptor

    Neurotensin receptor

    Neurotensin_receptor

  • VN1R3
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    VN1R3

    VN1R3

    VN1R3

  • VIPR1
  • Protein-coding gene in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    VIPR1

    VIPR1

    VIPR1

  • Adenosine receptor
  • Class of four receptor proteins to the molecule adenosine

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Adenosine receptor

    Adenosine receptor

    Adenosine_receptor

  • Neuromedin U receptor
  • InterPro Family

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Neuromedin U receptor

    Neuromedin_U_receptor

  • Corticotropin-releasing hormone receptor 2
  • Protein found in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Corticotropin-releasing hormone receptor 2

    Corticotropin-releasing hormone receptor 2

    Corticotropin-releasing_hormone_receptor_2

  • Pyroglutamylated RFamide peptide receptor
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Pyroglutamylated RFamide peptide receptor

    Pyroglutamylated RFamide peptide receptor

    Pyroglutamylated_RFamide_peptide_receptor

  • Parathyroid hormone 2 receptor
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Parathyroid hormone 2 receptor

    Parathyroid hormone 2 receptor

    Parathyroid_hormone_2_receptor

  • GPR6
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR6

    GPR6

    GPR6

  • Galanin receptor 2
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Galanin receptor 2

    Galanin receptor 2

    Galanin_receptor_2

  • Muscarinic acetylcholine receptor M5
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Muscarinic acetylcholine receptor M5

    Muscarinic acetylcholine receptor M5

    Muscarinic_acetylcholine_receptor_M5

  • List of MeSH codes (D12.776.124)
  • MeSH D12.776.124.486.274.024.270 – complement c5a MeSH D12.776.124.486.274.024.270.255 – complement c5a, des-arginine MeSH D12.776.124.486.274.050 – complement

    List of MeSH codes (D12.776.124)

    List_of_MeSH_codes_(D12.776.124)

  • Chemotaxis
  • Movement of an organism or entity in response to a chemical stimulus

    chemotactic activity. The availability of this technology led to the discovery of C5a, a major chemotactic factor involved in acute inflammation. The pioneering

    Chemotaxis

    Chemotaxis

    Chemotaxis

  • Electrical steel
  • Iron alloy optimized for magnetic properties

    C4 Yes Yes C5 High-resistance similar to C4 plus inorganic filler Yes No C5A As C5, but more weldable Yes No C5AS Anti-stick variant of C5 Yes Yes C6

    Electrical steel

    Electrical steel

    Electrical_steel

  • Hypoalbuminemia
  • Abnormally low levels of albumin in the blood

    It also inhibits inflammatory mediators such as TNF-α and complement 5a (C5a) to reduce the overall inflammatory response. A number of hormones (e.g.

    Hypoalbuminemia

    Hypoalbuminemia

    Hypoalbuminemia

  • Y-DNA haplogroups in populations of South Asia
  • PMID 24614885. In this paper, C consists of C5(currently C1b1a1)-M356* 3.2% and C5a(currently C1b1a1a)-P92 5.3%, F is F-M201*, H consists of H-M69* 1%, H1a-M39

    Y-DNA haplogroups in populations of South Asia

    Y-DNA_haplogroups_in_populations_of_South_Asia

  • Melanocortin 3 receptor
  • Mammalian protein found in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Melanocortin 3 receptor

    Melanocortin 3 receptor

    Melanocortin_3_receptor

  • Orexin receptor
  • G-protein-coupled receptor

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Orexin receptor

    Orexin_receptor

  • GPR75
  • Protein-coding gene in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR75

    GPR75

    GPR75

  • GPR64
  • Protein-coding gene in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR64

    GPR64

    GPR64

  • OPN5
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    OPN5

    OPN5

    OPN5

  • Thyrotropin receptor
  • Mammalian protein found in Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Thyrotropin receptor

    Thyrotropin receptor

    Thyrotropin_receptor

  • GPR158
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR158

    GPR158

    GPR158

  • Alternative complement pathway
  • Type of cascade reaction of the complement system

    activation (alternative, classical, or lectin). C5-convertase cleaves C5 into C5a and C5b. C5b binds sequentially to C6, C7, C8 and then to multiple molecules

    Alternative complement pathway

    Alternative complement pathway

    Alternative_complement_pathway

  • LPAR4
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    LPAR4

    LPAR4

    LPAR4

  • Type III hypersensitivity
  • Type of allergic reaction

    response which can be augmented by the complement system via the anaphylatoxin C5a. Ligation of Fc receptors on the surfaces of immune effector cells can give

    Type III hypersensitivity

    Type III hypersensitivity

    Type_III_hypersensitivity

  • TAAR3
  • Human pseudogene

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    TAAR3

    TAAR3

    TAAR3

  • Australian contribution to UNTAG
  • Australian Army contribution to the UN Transition Assistance Group

    11 and 14 March – Advance element of the ASC arrives in Namibia by USAF C5A. 31 March – SWAPO began major cross-border incursion of up to 800 PLAN combatants

    Australian contribution to UNTAG

    Australian contribution to UNTAG

    Australian_contribution_to_UNTAG

  • PLCB2
  • Protein-coding gene in the species Homo sapiens

    kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor". J. Biol. Chem. 270 (34): 19828–32. doi:10.1074/jbc.270.34.19828

    PLCB2

    PLCB2

    PLCB2

  • Prostaglandin EP4 receptor
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Prostaglandin EP4 receptor

    Prostaglandin EP4 receptor

    Prostaglandin_EP4_receptor

  • Melatonin receptor 1B
  • Protein found in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Melatonin receptor 1B

    Melatonin receptor 1B

    Melatonin_receptor_1B

  • List of country codes: A–K
  • letter code GMB FIPS country code GA License plate code WAG GS1 GTIN prefix — UNDP country code GAM WMO country code GB ITU callsign prefixes C5A-C5Z

    List of country codes: A–K

    List_of_country_codes:_A–K

  • GPR133
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR133

    GPR133

    GPR133

  • Eicosanoid receptor
  • Integral membrane protein G protein-coupled receptor

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Eicosanoid receptor

    Eicosanoid_receptor

  • MRGPRG
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    MRGPRG

    MRGPRG

    MRGPRG

  • Cholecystokinin receptor
  • G-protein coupled receptor

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Cholecystokinin receptor

    Cholecystokinin_receptor

  • P2Y receptor
  • Subclass of purinergic P2 receptors

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    P2Y receptor

    P2Y receptor

    P2Y_receptor

  • Luteinizing hormone/choriogonadotropin receptor
  • Transmembrane receptor found in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Luteinizing hormone/choriogonadotropin receptor

    Luteinizing hormone/choriogonadotropin receptor

    Luteinizing_hormone/choriogonadotropin_receptor

  • Royal Canadian Air Cadets
  • Canadian national youth military program

    as nautical training, marksmanship, garrison / field training or flying. C5A - FTU Dressed Down A functional order of dress worn when participating in

    Royal Canadian Air Cadets

    Royal Canadian Air Cadets

    Royal_Canadian_Air_Cadets

  • Leukotriene receptor
  • Protein family

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Leukotriene receptor

    Leukotriene_receptor

  • Melanin-concentrating hormone receptor
  • InterPro Family

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Melanin-concentrating hormone receptor

    Melanin-concentrating_hormone_receptor

  • S1PR4
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    S1PR4

    S1PR4

    S1PR4

  • Alpha-1D adrenergic receptor
  • Protein-coding gene in humans

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Alpha-1D adrenergic receptor

    Alpha-1D adrenergic receptor

    Alpha-1D_adrenergic_receptor

  • Neuropeptides B/W receptor 1
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Neuropeptides B/W receptor 1

    Neuropeptides B/W receptor 1

    Neuropeptides_B/W_receptor_1

  • EMR3
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    EMR3

    EMR3

    EMR3

  • Hydroxycarboxylic acid receptor 3
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Hydroxycarboxylic acid receptor 3

    Hydroxycarboxylic acid receptor 3

    Hydroxycarboxylic_acid_receptor_3

  • GPR114
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    GPR114

    GPR114

    GPR114

  • Angiotensin II receptor type 1
  • Protein-coding gene in the species Homo sapiens

    2 S Y 1 2 4 5 Neuromedin B U 1 2 Neurotensin 1 2 Other Anaphylatoxin C3a C5a 1 2 Angiotensin 1 2 Apelin Bombesin BRS3 GRPR NMBR Bradykinin B1 B2 Chemerin

    Angiotensin II receptor type 1

    Angiotensin II receptor type 1

    Angiotensin_II_receptor_type_1

  • Vasodilation
  • Widening of blood vessels

    respiratory dysfunction. Anaphylatoxins, specifically complement proteins C3a and C5a, bind to receptors on mast cells and basophils causing degranulation. Granules

    Vasodilation

    Vasodilation

    Vasodilation

  • Outline of immunology
  • Overview of and topical guide to immunology

    receptor of the immunoglobulin family) Anaphylatoxin receptors C3a receptor C5a receptor (CD88) C5AR2 Fc receptor Fc-gamma receptors (FcγR) FcγRI (CD64)

    Outline of immunology

    Outline_of_immunology

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Online names & meanings

  • Jeffres
  • Surname or Lastname

    English

    Jeffres

    English : variant of Jeffress.

  • YASUKO
  • Female

    Japanese

    YASUKO

    (康子) Japanese name YASUKO means "peaceful child."

  • Ganet
  • Girl/Female

    Hebrew

    Ganet

    Garden.

  • Maharaja
  • Boy/Male

    Indian, Sanskrit

    Maharaja

    Great King

  • Mehgna
  • Girl/Female

    Hindu, Indian

    Mehgna

    Sky

  • Mohana
  • Girl/Female

    Hindu

    Mohana

    Attractive

  • Celina
  • Girl/Female

    American, Australian, British, Celebrity, Christian, English, Greek, Indian, Italian, Latin, Polish, Portuguese, Swedish

    Celina

    Sky; Goddess of the Moon; Heavenly; Moon

  • Bhavi
  • Boy/Male

    Hindu, Indian

    Bhavi

    Emotional

  • Jairasa
  • Boy/Male

    Indian, Sanskrit

    Jairasa

    The Essence of Victory

  • Pavaka
  • Boy/Male

    Hindu, Indian, Sanskrit

    Pavaka

    Bright; Purifying

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