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Chemical compound
Bufadienolide is a chemical compound with steroid structure. Its derivatives are collectively known as bufadienolides, including many in the form of bufadienolide
Bufadienolide
Succulent plant native to Madagascar
Cotyledon and Adromischus), Kalanchoe pinnata has been found to contain bufadienolide cardiac glycosides These can cause cardiac poisoning, particularly in
Kalanchoe_pinnata
Genus of flowering plants in the stonecrop family
hypertension. A variety of bufadienolide compounds have been isolated from various Kalanchoe species. Five different bufadienolides have been isolated from
Kalanchoe
Chemical compound
Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac
Daigremontianin
Species of succulent
delagoensis is unwelcome because it displaces native plants and contains bufadienolide cardiac glycosides which can cause fatal poisoning, particularly in
Kalanchoe_delagoensis
Class of organic compounds
it to be classified as either a cardenolide or bufadienolide. Cardenolides differ from bufadienolides due to the presence of an "enolide," a five-membered
Cardiac_glycoside
Class of chemical compounds
found in toads can be divided by chemical structure in two groups: bufadienolides, which are cardiac glycosides (e.g., bufotalin, bufogenin), are compounds
Bufotoxin
Section of flowering plants
cotyledonosis. Kalanchoe pinnata may have similar chemical components, bufadienolide alkaloids. Descoings, B. (2006). "Le genre Kalanchoe (Crassulaceae):
Bryophyllum
Chemical compound
a derivative of the so-called bufadienolides, where it also has a steroid structure. A characteristic of bufadienolides is that they all contain two double
Arenobufagin
Chemical compound
respect to 0.1 gram of epinephrin presented. Bufagin and bufagins are bufadienolide derivatives. This means they are steroids with a six-membered lactone
Bufagin
Family of beetles
the steroid pyrones lucibufagins, similar to the cardiac stimulant bufadienolides found in some poisonous toads. All fireflies glow as larvae, where bioluminescence
Firefly
Species of flowering plant in the family Ranunculaceae
glycosides present in E.hyemalis include Eranthin A and B, belonging to the bufadienolide group, also found in (and named for) the toad venom bufotoxin. Bulbs
Eranthis_hyemalis
Species of succulent
glycosides, including bufadienolides, which are highly toxic to cattle, sheep, goats, and other livestock. The bufadienolides found in Cotyledon cause
Cotyledon_tomentosa
Chemical compound
digoxigenin digoxin medigoxin neoconvalloside ouabain strophanthidin Bufadienolide and marinobufagenin are similar in structure and function. Cardanolide
Cardenolide
Cyclic carboxylic ester
in substance class names like butenolide, macrolide, cardenolide or bufadienolide. To obtain the preferred IUPAC names, lactones are named as heterocyclic
Lactone
Species of snake
on the back of the neck that are used to store cardiotonic steroids (bufadienolides) sequestered from the toads in their diet. Rhabdophis tigrinus are resistant
Rhabdophis_tigrinus
Species of plant
The main active compounds are cardiac glycosides, including unique bufadienolides such as glucoscillaren A, proscillaridine A, scillaren A, scilliglaucoside
Drimia_maritima
Species of flowering plant
animals. A key compound in the roots of Helleborus niger is Hellebrin, a bufadienolide which has similar cardiac activity but is less toxic than the cardiac
Helleborus_niger
dermatitis. Kalanchoe delagoensis mother of millions Crassulaceae Contains bufadienolide cardiac glycosides which can cause cardiac poisoning, particularly in
List_of_poisonous_plants
Steroid lactone, mostly found in skin venom glands of toads
Bufonidae family. It contains a lactone ring, and hence is classified as a bufadienolide. The cardiotonic activity of resibufogenin is attributed to its structural
Resibufogenin
Chemical compound
(lucibufagin A, B, and C), and are in the same structural class as the bufadienolides. P.J. Leisch (Summer 2018). "Five things everyone should know about
Lucibufagin
Succulent plant native to Madagascar
Wagner, Hildebert; Fischer, Manfred; Lotter, Hermann (1985). "New Bufadienolides from Kalanchoe daigremontiana Hamet et Perr. (Crassulaceae)" (PDF).
Kalanchoe_daigremontiana
Species of amphibian
Knight, J. C. (1987). "Steroids and related natural products. 104. Bufadienolides. 36. Synthesis of bufalitoxin and bufotoxin". Journal of Organic Chemistry
Common_toad
side of the head of a cane toad secretes a bufotoxin (a mixture of bufadienolides) that is toxic to most animals. This poison does not exist in any native
Adaptations of Australian animals to cane toads
Adaptations_of_Australian_animals_to_cane_toads
Chemical compound
Bufanolide is a C24 steroid and, indirectly, a parent structure of bufadienolide. Its derivatives was found in Bufo and Scilla, as an aglycone of cardiac
Bufanolide
Species of amphibian
compound from the warts on its back. The secretion, containing toxic bufadienolides, is distasteful to predators and can be lethal to small mammals. The
Anaxyrus_fowleri
Amphibians that produce poison
venom Brazil Panamanian golden frog (Atelopus zeteki) Zetekitoxin AB, Bufadienolide Central Panama. American toad (Anaxyrus americanus) Bufotoxin eastern
Poisonous_amphibian
Ion channel enzyme pump found in the membrane of all animal cells
are adapted to cardiotonic steroid toxins such as cardenolides and bufadienolides. Insects adapted to cardiotonic steroids typically have a number of
Sodium–potassium_pump
Species of succulent
regions from Namibia to the southwestern South Africa. The plant contains bufadienolide-type cardiac glycoside cotyledoside which causes cotyledonosis or nenta
Tylecodon_paniculatus
Genus of snakes
on the back of the neck that are used to store cardiotonic steroids (bufadienolides) sequestered from their diet, mostly from toads but also from firefly
Rhabdophis
Genus of flowering plants
parts of Bowiea contain several active cardiac glycosides, including bufadienolide glycosides. The bulbs of this plant also contain compounds such as boworuboside
Bowiea
Species of amphibian
Panamanian golden frog has a variety of toxins, including steroidal bufadienolides and guanidinium alkaloids of the tetrodotoxin class. One of the latter
Panamanian_golden_frog
tissues, induce vomiting and blistering. Class I chemicals include bufadienolides, cantharidin, cyanides, cardenolides, and alkaloids, all of which have
Chemical_defense_in_insects
Family of flowering plants
highest concentration of cardiotoxins, the active ingredient being bufadienolides (named for their digoxin-like effect on Bufo toads). Illness in domestic
Crassulaceae
Chemical compound
Marinobufagenin (marinobufagin, MBG) is a cardiotonic bufadienolide steroid. It is secreted by the toad species such as Bufo marinus. It also can be found
Marinobufagenin
Panamanian golden frog has a variety of toxins, including steroidal bufadienolides and guanidinium alkaloids of the tetrodotoxin class. One of the latter
Animal attacks in Latin America
Animal_attacks_in_Latin_America
Pharmaceutical compound
Yashinov A, Mirakhmetova Z, Huang Y, et al. (August 2023). "Toad venom bufadienolides and bufotoxins: An updated review". Drug Development Research. 84 (5):
Dehydrobufotenine
Species of succulent
from Namaqualand into the Great and Little Karoo. The plant contains bufadienolide-type cardiac glycoside cotyledoside which causes nenta poisoning ("krimpsiekte")
Tylecodon_wallichii
Christo (March 2022). "Cardiac glycoside intoxication - CUMULATIVE BUFADIENOLIDE POISONING" (PDF). University of Pretoria. Archived from the original
John_Croumbie_Brown
Species of succulent plant
The leaves and flowers contain a group of toxic glycosides known as bufadienolides, which can cause acute cardiac toxicity and death when ingested in large
Kalanchoe_lanceolata
Chemical compound
including hepatocellular and lung carcinoma. However, as with other bufadienolides, its potential use is hampered by its cardiotoxicity. A Dasgupta, P
Bufalin
Subfamily of bulbous monocot plants
divide the tribe into 19 genera. Species within this tribe contain bufadienolides and are distributed mainly in Africa, Madagascar, and the Mediterranean
Scilloideae
Natural anti-predator mechanism
produced by newts and pufferfish are derived from invertebrate prey. Bufadienolides, defensive chemicals produced by toads, have been found in glands of
Chemical_defense
Class of chemical compounds
Yoshihiro Tanaka, Manki Komatsu (1968), "The Isolation and Structure of new Bufadienolides, 3-(Hydrogen suberates) of Resibufogenin, Cinobufagin and Bufalin –
Steroidal_alkaloid
Genus of flowering plants
toxicity. The best-known active ingredients of Tylecodon species are bufadienolides biochemically related to toad venoms and bile acids. In some species
Tylecodon
Chemical compound
used in traditional Chinese medicine. Cinobufagin, as well as other bufadienolides, can be isolated from the traditional Chinese medicine called ChanSu
Cinobufagin
Chemical compound
(January 2012). "Protective effect of taurine on cardiotoxicity of the bufadienolides derived from toad (Bufo bufo gargarizans Canto) venom in guinea-pigs
Bufotalin
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