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BRD2

  • BRD2
  • Protein-coding gene in the species Homo sapiens

    Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family

    BRD2

    BRD2

    BRD2

  • BET inhibitor
  • Drug class

    the bromodomains of Bromodomain and Extra-Terminal motif (BET) proteins BRD2, BRD3, BRD4, and BRDT, and prevent protein-protein interaction between BET

    BET inhibitor

    BET_inhibitor

  • JQ1
  • Chemical compound

    potent inhibitor of the BET family of bromodomain proteins which include BRD2, BRD3, BRD4, and the testis-specific protein BRDT in mammals. BET inhibitors

    JQ1

    JQ1

    JQ1

  • Bromodomain-containing protein 3
  • Protein-coding gene in the species Homo sapiens

    gene was identified based on its homology to the gene encoding the RING3 (BRD2) protein, a serine/threonine kinase. The gene maps to 9q34, a region which

    Bromodomain-containing protein 3

    Bromodomain-containing protein 3

    Bromodomain-containing_protein_3

  • Admiral of the Navy
  • Rank in the United States Navy

    Government Printing Office, 1909. Page 39. "Chapter 94: Gun Salutes" (PDF). BRd2 - The Queens Regulations for the Royal Navy. Royal Navy. April 2017. p. 94-12

    Admiral of the Navy

    Admiral of the Navy

    Admiral_of_the_Navy

  • BRD4
  • Protein-coding gene in the species Homo sapiens

    BET (bromodomain and extra terminal domain) family, which also includes BRD2, BRD3, and BRDT. BRD4, similar to other BET family members, contains two

    BRD4

    BRD4

    BRD4

  • Birabresib
  • Chemical compound

    Birabresib (OTX-015, MK-8628) is an experimental small molecule inhibitor of BRD2, BRD3, and BRD4 under investigation for the treatment of cancer. It is in

    Birabresib

    Birabresib

    Birabresib

  • LY294002
  • Chemical compound

    perturbation of synaptotagmin function. LY294002 is also a BET inhibitor (e.g. of BRD2, BRD3, and BRD4). It has been shown that LY294002 administration has an additive

    LY294002

    LY294002

    LY294002

  • The Citadel
  • Military college in Charleston, South Carolina, US

    June 26, 2015. Retrieved May 29, 2015. "Standards, Flags, and Colours". BRd2 – The Queens Regulations for the Royal Navy (PDF). Ministry of Defence (United

    The Citadel

    The_Citadel

  • Bromodomain
  • Protein domain

    (Bromodomain and extraterminal domain) family. Members of this family include BRD2, BRD3, BRD4 and BRDT. However proteins such as ASH1L also contain a bromodomain

    Bromodomain

    Bromodomain

    Bromodomain

  • BRDT
  • Protein-coding gene in humans

    chromatin reorganization. As BET inhibitors also inhibit other BET proteins BRD2, BRD3, and BRD4, they are likely to have effects in people beyond temporary

    BRDT

    BRDT

    BRDT

  • Customs and traditions of the Royal Navy
  • Written Answers, UK Parliament, Column 361W, 5 September 2014 "para9136". BRd2 (PDF). Royal Navy. April 2017. p. 91-16. Jolly, Rick (2011). Jackspeak: A

    Customs and traditions of the Royal Navy

    Customs and traditions of the Royal Navy

    Customs_and_traditions_of_the_Royal_Navy

  • RUNX3
  • Protein-coding gene in humans

    is acetylated by p300 to complex with bromodomain-containing protein 2 (BRD2; a member of the BET family of transcription co-regulators) and to subsequent

    RUNX3

    RUNX3

    RUNX3

  • BRD
  • Topics referred to by the same term

    requirements document .BRD, a file type in the EAGLE design automation software BRD2, BRD3, BRD4 and BRDT, bromodomain families Business requirements document

    BRD

    BRD

  • BRD7
  • Protein-coding gene in the species Homo sapiens

    Peng C, Nie XM, et al. (2003). "[Expression of BRD7-interacting proteins, BRD2 and BRD3, in nasopharyngeal carcinoma tissues]". AI Zheng. 22 (2): 123–7

    BRD7

    BRD7

    BRD7

  • Pelabresib
  • Investigational oral small-molecule drug

    approved for clinical use. Pelabresib is a selective inhibitor of BET proteins (BRD2, BRD3, BRD4, BRDT), which regulate gene expression by binding to acetylated

    Pelabresib

    Pelabresib

    Pelabresib

  • Juvenile myoclonic epilepsy
  • Medical condition causing seizures

    may be the result of a brain developmental disorder. Three SNP alleles in BRD2, Cx-36 and ME2 and microdeletions in 15q13.3, 15q11.2 and 16p.13.11 also

    Juvenile myoclonic epilepsy

    Juvenile_myoclonic_epilepsy

  • List of human protein-coding genes 1
  • HGNC:1101; P51587 1651 BRCC3 HGNC:24185; P46736 1652 BRD1 HGNC:1102; O95696 1653 BRD2 HGNC:1103; P25440 1654 BRD3 HGNC:1104; Q15059 1655 BRD3OS HGNC:24742; A0A1B0GUI7

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • Ming-Ming Zhou
  • Chinese-American scientist

    DR, Walsh MJ, Xiong H, Zeng L, Zhou MM (March 2017). "Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation"

    Ming-Ming Zhou

    Ming-Ming Zhou

    Ming-Ming_Zhou

  • Curt M. Horvath
  • American virologist

    Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2. iScience. 2018;6:68-82. Epub 2018/09/22. doi: 10.1016/j.isci.2018.07.013

    Curt M. Horvath

    Curt_M._Horvath

  • Bump and hole
  • Tool in chemical genetics

    lysine on nucleosomal histones. Recently, four members of the BET family, BRD2, 3, 4, and BRDT, each containing two bromodomains, were identified as important

    Bump and hole

    Bump and hole

    Bump_and_hole

  • Chem-seq
  • Technique for mapping interactions between molecules and their protein targets

    binding of the bromodomain inhibitor JQ1 to the BET bromodomain family members BRD2, BRD3 and BRD4 2) Map the genomic binding sites of AT7519, an inhibitor of

    Chem-seq

    Chem-seq

  • E2F2
  • Protein-coding gene in the species Homo sapiens

    overall 46% amino acid identity to E2F1. E2F2 has been shown to interact with: BRD2, RYBP, and RB1. E2F ENSG00000282899 GRCh38: Ensembl release 89: ENSG00000007968

    E2F2

    E2F2

    E2F2

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Online names & meanings

  • Alphonso
  • Boy/Male

    American, Australian, Chinese, French, German, Teutonic

    Alphonso

    Ready for a Fight; Noble and Ready

  • Khrystyne
  • Girl/Female

    Russian

    Khrystyne

    Christian.

  • HOWEL
  • Male

    English

    HOWEL

    Variant spelling of English Howell, HOWEL means "eminent, conspicuous."

  • ADELE
  • Female

    English

    ADELE

    English form of French Adèle, ADELE means "noble sort."

  • Sheelarani
  • Girl/Female

    Hindu, Indian

    Sheelarani

    Decent

  • Yavanika | யாவநீகா
  • Girl/Female

    Tamil

    Yavanika | யாவநீகா

    Curtain of stage

  • ÁSGEIRR
  • Male

    Norse

    ÁSGEIRR

    Old Norse name composed of the elements �ss "god" and geirr "spear," hence "god-spear." Equivalent to Old High German Ansgar.

  • Sairi |
  • Girl/Female

    Muslim

    Sairi |

    Satisfaction, Saturation

  • TSELOPHCHAD
  • Male

    Hebrew

    TSELOPHCHAD

    (צְלָפְחָד) Hebrew name TSELOPHCHAD means "first rupture; fracture," taken to mean "first-born." In the bible, this is the name of a member of the tribe Manasseh.

  • TIRTSAH
  • Female

    Hebrew

    TIRTSAH

    (תִּרְצָה) Hebrew name TIRTSAH means "pleasantness." In the bible, this is a place name and the name of a daughter of Zelophehad.

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BRD2

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