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AUTOLYSIN

  • Autolysin
  • Class of enzymes

    Autolysins are endogenous lytic enzymes that break down the peptidoglycan components of biological cells which enables the separation of daughter cells

    Autolysin

    Autolysin

  • Staphylococcus aureus
  • Species of Gram-positive bacterium

    fission. Complete separation of the daughter cells is mediated by S. aureus autolysin, and in its absence or targeted inhibition, the daughter cells remain

    Staphylococcus aureus

    Staphylococcus aureus

    Staphylococcus_aureus

  • Lysibody
  • binding domain from a bacteriophage lysin, or the binding domain from an autolysin or bacteriocin, all of which bind to bacterial cell wall carbohydrate

    Lysibody

    Lysibody

  • Penicillin
  • Group of antibiotics derived from fungi

    precursors triggers the activation of bacterial cell wall hydrolases and autolysins, which further digest the cell wall's peptidoglycans. The small size of

    Penicillin

    Penicillin

    Penicillin

  • Staphylococcus epidermidis
  • Species of bacterium

    Yang L, Zhu Y, Tolker-Nielsen T, Molin S, et al. (July 2007). "Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis"

    Staphylococcus epidermidis

    Staphylococcus epidermidis

    Staphylococcus_epidermidis

  • LysM domain
  • Protein domain

    design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin". FEMS Microbiology Letters. 70 (3): 257–64. doi:10.1016/0378-1097(92)90707-u

    LysM domain

    LysM domain

    LysM_domain

  • Autophagy
  • Process of cells digesting parts of themselves

    autophagy targeting proteins. And the specialized virulence factors such as autolysins, and iron sequestering proteins are potentially recognized uniquely by

    Autophagy

    Autophagy

    Autophagy

  • Pneumococcal infection
  • Medical condition

    pore-forming protein that can cause lysis of host cells and activate complement Autolysin (LytA)—activation of this protein lyses the bacteria releasing its internal

    Pneumococcal infection

    Pneumococcal_infection

  • Peptidoglycan binding domain
  • Class of protein structural domains

    cwlA precursor (cell wall hydrolase, autolysin, EC 3.5.1.28) Autolytic lysozyme (1,4-beta-N-acetylmuramidase, autolysin, EC 3.2.1.17) Membrane-bound lytic

    Peptidoglycan binding domain

    Peptidoglycan binding domain

    Peptidoglycan_binding_domain

  • Teichoic acid
  • Copolymers found in some bacteria

    acids also assist in regulation of cell growth by limiting the ability of autolysins to break the β(1-4) bond between the N-acetyl glucosamine and the N-acetylmuramic

    Teichoic acid

    Teichoic acid

    Teichoic_acid

  • Hol118 family
  • The reaction probably catalyzed is: small molecules + autolysin (in) → small molecules + autolysin (out) Holin Lysin Transporter Classification Database

    Hol118 family

    Hol118_family

  • Lysin (disambiguation)
  • Topics referred to by the same term

    lysis, such as: Most commonly, phage lysins, also known as endolysins Autolysin Cytolysin Egg lysin Hemolysin NK-lysin Streptolysin Cell lysis Toxin This

    Lysin (disambiguation)

    Lysin_(disambiguation)

  • Lysin
  • Class of enzymes

    membrane proteins that activate the host's autolytic mechanisms such as autolysins. Lysins were first used therapeutically in 2001 and are now being used

    Lysin

    Lysin

    Lysin

  • Pseudomonas aeruginosa hol holin family
  • autolysis system. The reaction probably catalyzed by Hol is: Autolysin (Lys)in → Autolysin (Lys)out. Holin Lysin Holin Superfamily III Transporter Classification

    Pseudomonas aeruginosa hol holin family

    Pseudomonas_aeruginosa_hol_holin_family

  • P35 holin family
  • Xylella fastidiosa strains. The reaction catalyzed by P35 holin is: autolysin (in) → autolysin (out) Bacteriophage Phage typing Holin Lysin Transporter Classification

    P35 holin family

    P35_holin_family

  • Antimicrobial peptides
  • Class of peptides that have antimicrobial activity

    wall synthesis, alteration of the cytoplasmic membrane, activation of autolysin, inhibition of DNA, RNA, and protein synthesis, and inhibition of certain

    Antimicrobial peptides

    Antimicrobial peptides

    Antimicrobial_peptides

  • Cefotaxime
  • Chemical compound

    eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) in the absence of cell wall assembly. Due to the

    Cefotaxime

    Cefotaxime

    Cefotaxime

  • Carbapenem-resistant enterobacteriaceae
  • Antibiotic-resistant bacteria

    weakened from the absence of cross-linkages. The continued activity of autolysins, that function like lysozymes and cleave glycosidic and peptide bonds

    Carbapenem-resistant enterobacteriaceae

    Carbapenem-resistant_enterobacteriaceae

  • Glycopeptide antibiotic
  • Class of antibiotic drugs

    structurally and ancestrally related to vancomycin, but they work by inhibiting autolysins through binding to peptidoglycan, therefore preventing cell division,

    Glycopeptide antibiotic

    Glycopeptide antibiotic

    Glycopeptide_antibiotic

  • Piperacillin
  • Antibiotic medication

    other substrates from binding. Moreover, this leads to the release of autolysins that break down the bacteria's cell wall. Some β-lactamase enzymes also

    Piperacillin

    Piperacillin

    Piperacillin

  • CHAP domain
  • Protein family

    trypanosomal glutathionylspermidine amidases. A variety of bacterial autolysins. A Nocardia aerocolonigenes putative esterase. Streptococcus pneumoniae

    CHAP domain

    CHAP domain

    CHAP_domain

  • Merivirus
  • Genus of viruses

    of phage-encoded proteins P17 and P18 as well as an unidentified host autolysin. However, identification of PM2-like proviruses in bacterial genomes indicates

    Merivirus

    Merivirus

    Merivirus

  • S. P. Beebe
  • American scientist

    PUTS BEBEE OUT OF CORNELL; College Objects to Doctor's Exploitation of Autolysin and Ends His Department. Triolo, Victor A. and Riegel, Ilse L. (1961)

    S. P. Beebe

    S._P._Beebe

  • ACES (buffer)
  • Chemical compound

    of ACES has been published in a protocol for the analysis of bacterial autolysins in a discontinuous SDS-PAGE system. Potential inhibition of ACES and other

    ACES (buffer)

    ACES (buffer)

    ACES_(buffer)

  • Glutamyl endopeptidase GluV8
  • Extracellular serine protease

    Narayana SV, Schneewind O (October 2013). "Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus". The Journal of Biological

    Glutamyl endopeptidase GluV8

    Glutamyl endopeptidase GluV8

    Glutamyl_endopeptidase_GluV8

  • N-acetylmuramoyl-L-alanine amidase
  • Class of enzymes

    peptidoglycan biosynthesis. Autolysins and some phage lysins are examples of N-acetylmuramoyl-L-alanine amidases. Phage lysins Autolysins PGLYRP2 Campbell JN;

    N-acetylmuramoyl-L-alanine amidase

    N-acetylmuramoyl-L-alanine amidase

    N-acetylmuramoyl-L-alanine_amidase

  • Phi11 holin family
  • functional in gram-negative bacteria: triggering of the major pneumococcal autolysin in Escherichia coli". Molecular Microbiology. 19 (4): 667–681. doi:10

    Phi11 holin family

    Phi11_holin_family

  • LCP family
  • Protein domain

    thought as the LytR (lytic repressor) component of a LytABC operon encoding autolysins, but the mechanism of regulation was later realized to be the production

    LCP family

    LCP_family

  • CidA/LrgA holin
  • Class of transmembrane transport proteins

    protein with 4 putative TMSs, is believed to be the holin which exports the autolysin CidB, while LrgA may be an anti-holin, a protein that binds and inhibits

    CidA/LrgA holin

    CidA/LrgA_holin

  • Glutamyl endopeptidase I
  • Sthanam V. L.; Schneewind, Olaf (2013-10-11). "Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus". The Journal of Biological

    Glutamyl endopeptidase I

    Glutamyl_endopeptidase_I

  • Lambda holin family
  • coli. Thus, it appears that holins can export various toxins as well as autolysins. The holes caused by S105 have an average diameter of 340 nm, and some

    Lambda holin family

    Lambda_holin_family

  • Corbomycin
  • Glycopeptide antibiotic

    of antibiotics that are produced by soil bacteria. Corbomycin blocks autolysins by attaching to the peptidoglycan cell wall. As a result, the bacterium

    Corbomycin

    Corbomycin

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Online names & meanings

  • Sadhumati
  • Girl/Female

    Hindu, Indian, Marathi, Sanskrit

    Sadhumati

    Virtuous Minded

  • Thorndyke
  • Boy/Male

    British, English

    Thorndyke

    From the Thorny Dike

  • Butts
  • Boy/Male

    Shakespearean

    Butts

    King Henry the Eighth' Doctor Butts, physician to the King.

  • Anbessa
  • Boy/Male

    Spanish

    Anbessa

    A Saracen governor of Spain.

  • MacIver
  • Boy/Male

    Scottish

    MacIver

    Son of an archer.

  • AbuSaeed
  • Boy/Male

    Arabic, Muslim

    AbuSaeed

    Father of Dignified; Name of a Sahabi (R.A)

  • LlewelIyn
  • Boy/Male

    Welsh

    LlewelIyn

    Lion.

  • ANSAPATA
  • Male

    Egyptian

    ANSAPATA

    , an Elamite deity.

  • Hardial
  • Boy/Male

    Sikh

    Hardial

    One on whom there is gods grace, Gods mercy

  • Suruchira
  • Girl/Female

    Hindu

    Suruchira

    Beautiful

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AUTOLYSIN

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