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Search references for ARF6. Phrases containing ARF6
See searches and references containing ARF6!ARF6
Protein-coding gene in the species Homo sapiens
ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that
ARF6
Group of proteins
poorly or not at all to the GDP nucleotide. Structural studies of Arf1 and Arf6 have revealed that although these proteins feature the switch 1 and 2 conformational
ADP_ribosylation_factor
Free radical toxicity
"Nicotine-free electronic vape fluid stimulates angiogenic processes in vitro through ARF6-mediated oxidative stress". Frontiers in Toxicology. 7. doi:10.3389/ftox
Oxidative_stress
Prevalent tubulovesicular membranes
uptake of external cargo. ARF6 is involved in the uptake of major histocompatibility class 1 proteins. While it is assumed ARF6 is not needed for endocytosis
Clathrin-independent endocytosis
Clathrin-independent_endocytosis
Bacterial infection of the small intestine
freed to bind with a human partner protein called ADP-ribosylation factor 6 (Arf6). Binding exposes its active site, allowing it to permanently ribosylate
Cholera
Protein of the immune system
G, Derrien V, Tenza D, Rossé C, Camonis J, Chavrier P (December 2003). "ARF6 controls post-endocytic recycling through its downstream exocyst complex
MHC_class_II
Protein complex secreted by the bacterium Vibrio cholerae
in the cytosol rather than be degraded by the proteasome. CTA1 binds to ARF6-GTP (ADP-ribosylation factor 6) in the cytosol, which induces a conformational
Cholera_toxin
Protein superfamily of small GTPases
RAP1B; RAP2A; RAP2B; RAP2C Arf vesicular transport ARF1; ARF3; ARF4; ARF5; ARF6; ARL1; ARL2; ARL3; ARL4; ARL5; ARL5C; ARL6; ARL7; ARL8; ARL9; ARL10A; ARL10B;
Ras_superfamily
American-Indian biologist
and diagnostics tools to cure cancer, specifically ARF6. Her research led to the discovery that ARF6 played a role in endosomal membrane trafficking and
Crislyn_D'Souza-Schorey
Protein-coding gene in the species Homo sapiens
Tempst P, Spiegelman BM (1994). "Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and
Retinoid_X_receptor_alpha
Protein-coding gene in the species Homo sapiens
GTPases ADP-ribosylation factor (ARF) 1 and ARF5 and weak activity towards ARF6. The encoded protein is believed to function as an ARF GAP that controls
ASAP2
Protein-coding gene in the species Homo sapiens
categorized as class I (ARF1 and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. The ARF4 gene
ARF4
Protein and coding gene in humans
necessary for the pre-coupling. It has also been shown to interact with Arf6 and ARF1. Muscarinic acetylcholine receptor GRCh38: Ensembl release 89: ENSG00000133019
Muscarinic acetylcholine receptor M3
Muscarinic_acetylcholine_receptor_M3
Protein family
trisphosphate, V-ATPase and ARNO (a guanine nucleotide exchange factor of ARF6). These associations are thought to be predominantly involved in cellular
Fructose-bisphosphate aldolase
Fructose-bisphosphate_aldolase
component of the complex) and Arf small GTPases (such as ARF1, ARF5, and ARF6 ) or the similar protein ARL1, which causes dissociation of the CYFIP1-Nap1-Abi2
WAVE_regulatory_complex
Protein-coding gene in the species Homo sapiens
Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA (October 2000). "ACAPs are arf6 GTPase-activating proteins that function in the cell periphery". The Journal
IFFO1
Protein-coding gene in the species Homo sapiens
"CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration". Exp. Cell Res. 318 (3): 228–37. doi:10.1016/j
CNKSR3
Protein-coding gene in the species Homo sapiens
Schonteich E, Matheson J, et al. (2006). "Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis". EMBO J. 24 (19):
RAB11FIP4
Protein-coding gene in the species Homo sapiens
phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein for ARF6 that is involved in actin cytoskeleton organization" (PDF). The Journal of
Centaurin,_alpha_1
vapor induces oxidative stress in human endothelial cells via activation of ARF6 and its guanine nucleotide exchange factor ARNO. This oxidative stress promotes
Health effects of electronic cigarettes
Health_effects_of_electronic_cigarettes
Protein-coding gene in the species Homo sapiens
large protein family of TRP ion channels. TRPML2 is associated with the Arf6-regulated trafficking pathway and is involved in the intracellular transport
MCOLN2
Protein-coding gene in the species Homo sapiens
exchange factor that promotes binding of GTP to ADP ribosylation factor protein ARF6 and to a lesser extent ARF1 and ARF5. This activates the ADP-ribosylation
IQSEC1
Prevalent tubulovesicular membranes
CLIC/GEEC endocytic pathway, which is regulated by GRAF1. Each of RhoA, Arf6, or Cdc42 has the capacity to modulate one of the three distinct clathrin-independent
Clathrin-independent_carrier
Protein-coding gene in humans
'KIAA1110', under which name it was found to act as a GEF for Arf1 but not Arf6. It is related to the other Arf-GEF protein IQSEC1. "www.genenames.org".
IQSEC3
Protein-coding gene in humans
5)P2)-rich membranes and signals to endosomes, leading to activation of ARF6, a key regulator of endocytosis. A-Raf may contribute to tumorigenesis through
ARAF
Class of kinase enzymes
4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation". Cell. 99 (5): 521–32. doi:10.1016/s0092-8674(00)81540-8
Phosphatidylinositol-4-phosphate 5-kinase
Phosphatidylinositol-4-phosphate_5-kinase
Protein-coding gene in the species Homo sapiens
exchange factor for Rac/Cdc42, and GIT1, a GTPase activating protein for ARF6 implicated in receptor recycling and exocytosis. SCRIB is found in the cell
SCRIB
Protein-coding gene in the species Homo sapiens
exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The CYTH4 and CYTH1 gene structures are very similar. GRCh38: Ensembl release
CYTH4
Protein-coding gene in the species Homo sapiens
Torii T, Natsume W, et al. (2005). "A novel GTPase-activating protein for ARF6 directly interacts with clathrin and regulates clathrin-dependent endocytosis"
SMAP1
Species of intracellular parasite
infection. Amastigotes of L. donovani enter macrophages via a Rac1- and Arf6-dependent process, and are found in phagocytic vacuoles that interact with
Leishmania_donovani
Protein-coding gene in the species Homo sapiens
S (2007). "The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane". Curr. Biol. 17 (8): 711–6. Bibcode:2007CBio
ARL4A
Protein-coding gene in humans
phosphatidylinositol 3,4, 5-trisphosphate-stimulated GTPase-activating proteins for ARF6". The Journal of Biological Chemistry. 275 (18): 13901–6. doi:10.1074/jbc
GIT2
Protein-coding gene in the species Homo sapiens
humans is encoded by the ARFIP2 gene. ARFIP2 has been shown to interact with Arf6, ARF3, ARF5 and RAC1. GRCh38: Ensembl release 89: ENSG00000132254 – Ensembl
ARFIP2
Protein-coding gene in the species Homo sapiens
class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. The ARF5 gene
ARF5
HGNC:654; P61204 920 ARF4 HGNC:655; P18085 921 ARF5 HGNC:658; P84085 922 ARF6 HGNC:659; P62330 923 ARFGAP1 HGNC:15852; Q8N6T3 924 ARFGAP2 HGNC:13504; Q8N6H7
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in the species Homo sapiens
initiates unfolded protein response (UPR) by activating Ire1, Xbp1, and Arf6, allowing the plasma B cells to produce vast amounts of antibody. BLIMP-1
PRDM1
Mammalian protein found in Homo sapiens
cytoskeleton remodeling through interacting with cytohesin-2 (ARNO) and Arf6. ALDOA is ubiquitously expressed in most tissues, though it is predominantly
Aldolase_A
Protein-coding gene in the species Homo sapiens
further pack helically onto the membrane. CENTB1 interacts with GTP-bound ARF6, regulating polymerization of the actin cytoskeleton around the plasma membrane
CENTB1
Protein-coding gene in the species Homo sapiens
TRE17 Regulates Plasma Membrane-Endosomal Trafficking through Activation of Arf6". Mol. Cell. Biol. 24 (22): 9752–62. doi:10.1128/MCB.24.22.9752-9762.2004
USP6
Protein domain
K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA (2000). "ACAPs are arf6 GTPase-activating proteins that function in the cell periphery". The Journal
TBC_domain
Protein-coding gene in the species Homo sapiens
membrane trafficking. CYTH2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. CYTH2 protein is 83% homologous to CYTH1. Two transcript variants encoding
CYTH2
Protein-coding gene in the species Homo sapiens
epithelial cell surface polarity. EXOC5 has been shown to interact with Arf6. GRCh38: Ensembl release 89: ENSG00000070367 – Ensembl, May 2017 GRCm38:
EXOC5
Protein-coding gene in the species Homo sapiens
as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein
ARF1
Protein-coding gene in the species Homo sapiens
(November 2006). "ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP". Journal
CENTD1
Protein-coding gene in the species Homo sapiens
class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene
ARF3
Protein-coding gene in the species Homo sapiens
domain that binds PI(3,4,5)P3 in vitro. ARAP1 prefers Arf1 and Arf5 over Arf6 as substrate. The GAP activity exerted on Rho proteins is not dependent on
ARAP1
centromeric protein CENPH, the BAX Inhibitor TMBI4, the ADP ribosylation factor ARF6, the kinase TNIK, and the transcriptional repressor T22D1. The number of
KIAA0090
(November 2009). "Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity". Nat. Cell Biol. 11 (11): 1325–31. doi:10.1038/ncb1976. PMC 2854659
Slit-Robo
Protein-coding gene in the species Homo sapiens
and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this
CENTD3
Protein-coding gene in the species Homo sapiens
co-complex interactions. CAC1A, QCR1, UQCRC1, CACNA1A, STOM, a8k1f4, HLA-B, ARF6, and Mapk3 have been found to interact with UQCRC2. GRCh38: Ensembl release
UQCRC2
Protein-coding gene in the species Homo sapiens
H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6". Molecular and Cellular Biology. 23 (2): 645–54. doi:10.1128/MCB.23.2.645-654
RALA
Protein-coding gene in the species Homo sapiens
M211397200. PMID 12682053. Krauss M, Kinuta M, Wenk MR, et al. (2003). "ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating
PIP5K1C
Protein-coding gene in the species Homo sapiens
Minetti C, Benfenati F, Fassio A, Zara F (September 2010). "TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy"
TBC1D24
Pharmaceutical compound
"Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6". Journal of Cell Science. 131 (12) jcs213314. doi:10.1242/jcs.213314. PMC 6031383
SH-BC-893
Human protein and coding gene
clathrin-mediated endocytosis. Arrestin beta 1 has been shown to interact with Arf6, PTHLH, DVL2 Mdm2, OPRD1, PSCD2, and RALGDS. GRCh38: Ensembl release 89:
Arrestin_beta_1
Protein-coding gene in the species Homo sapiens
(Dec 2002). "HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway". Cell. 111 (6): 853–66. doi:10.1016/S0092-8674(02)01162-5
PACS1
Protein-coding gene in the species Homo sapiens
4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation". Cell. 99 (5): 521–32. doi:10.1016/S0092-8674(00)81540-8
PIP5K1A
Protein-coding gene in the species Homo sapiens
Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA (Nov 2000). "ACAPs are arf6 GTPase-activating proteins that function in the cell periphery". J Cell Biol
CENTB2
Protein-coding gene in humans
Sun-Wada GH, Bourgoin S, et al. (2006). "V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway". Nat. Cell
ATP6V0A2
Protein-coding gene in the species Homo sapiens
with partner proteins, and a C-terminal tail domain, which includes the Arf6-interacting domain important for regulatory functions. The protein exists
KIF23
CDC42, CDH1, CLIP1, PRKACA, RAC1, and S100B. Actin – cytoskeletal structure ARF6 APC Beta-catenin–cell adhesion and WNT signaling: transcription B-raf – MAPK
IQGAP1
Dutch academic
Klausner, R. D. (1995-03-15). "Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments". J Cell
Peter_J._Peters
Genetic disorder
organization and neuronal development in the brain by reduced activation of the ARF6 substrate or a defect in the GTP-binding activity. Two intragenic duplications
Xp11.2_duplication
Protein-coding gene in the species Homo sapiens
Krauss M, Kinuta M, Wenk MR, De Camilli P, Takei K, Haucke V (July 2003). "ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating
SNAP91
major histocompatibility complex class I down-modulation is independent of Arf6 activity". Molecular Biology of the Cell. 15 (1): 323–331. doi:10.1091/mbc
EHD_protein_family
Protein-coding gene in the species Homo sapiens
(Apr 2007). "The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane". Current Biology. 17 (8): 711–6
ARL4D
ARF6
ARF6
ARF6
ARF6
Girl/Female
Tamil
Humsiha | ஹà¯à®®à®¸à¯€à®¹à®¾Â
Saraswati, Luckiest girl
Boy/Male
Indian
Rocks
Male
English
Unisex short form of English Stephen and Stephanie, both STEPH means "crown."
Boy/Male
Hindu
First of ramas twin son (Son of Lord Rama)
Boy/Male
Tamil
Life, Soul
Boy/Male
Arabic, Muslim
A Garnet; Ruby; A Precious Stone
Surname or Lastname
English
English : probably a habitational name from a lost or unidentified place.Probably an altered spelling of German Rams(e)l, Dutch Ramsel, a habitational name from Ramsel in Antwerp province, Belgium; a group of people migrated from there to Swabia in 1570.In some instances the German name may have derived from a nickname for a roguish person.
Surname or Lastname
English
English : variant of Bink; this is much the commoner form of the surname in the British Isles.
Girl/Female
English
A well-established compound of Jo-.
Boy/Male
Indian, Sanskrit
Successful; Prosperous
ARF6
ARF6
ARF6
ARF6
ARF6