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Chemical compound
Apamin is an 18 amino acid globular peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks
Apamin
Effect of long-term ergot poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Ergotism
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Barbiturate_overdose
Toxic effects of thallium
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Thallium_poisoning
Toxin secreted by an animal
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Venom
Broad-spectrum poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Cyanide_poisoning
Venom made by bees
Adolapin contributes 2–5% of the peptides. Further protein components include apamin (2%), a neurotoxin, hyaluronidase (2%), which dilates blood vessels, increasing
Apitoxin
Puncture wound caused by a bee's stinger
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Bee_sting
Symptoms caused by an excess of serotonin in the central nervous system
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Serotonin_syndrome
Substance that causes death, injury or harm to organs
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Poison
Medical condition (poisoning)
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Methanol_toxicity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Argyria
Toxicity due to paracetamol overdose
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Paracetamol_poisoning
Poisoning of humans from pesticide exposure
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Pesticide_poisoning
Type of metal poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Copper_toxicity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Chromium_toxicity
Toxic effects of carbon monoxide
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Carbon_monoxide_poisoning
Use of an excessive amount of a drug
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Drug_overdose
Poisoning caused by lead in the body
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Lead_poisoning
sequence similarity to other toxins that can compete with the binding site of apamin is much lower. It is 31 amino acids long and its weight is 3458 daltons
Tamapin
Poisoning caused by mercury chemicals
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Mercury_poisoning
Human disease
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Vitamin_D_toxicity
Dose dependant harmfulness of substances
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Toxicity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Chlorine_gas_poisoning
Toxic effects of ingesting too much vitamin A
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Hypervitaminosis_A
Medical condition resulting from overconsumption of bromine (Br)
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Bromism
Injury caused by bite from snakes
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Snakebite
Harmful effects of certain metals
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Metal_toxicity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Calcium channel blocker toxicity
Calcium_channel_blocker_toxicity
Toxic effects of breathing oxygen at high partial pressures
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Oxygen_toxicity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Salicylate_poisoning
Illness from ingesting arsenic
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Arsenic_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Nicotine_poisoning
Species of wasp
neurotransmitters such as dopamine, serotonin, histamine and noradrenaline neurotoxin apamin, as well as enzymes phospholipase A and hyaluronidase, and proteins melittin
European_hornet
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Strychnine_poisoning
Bite caused by a spider
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Spider_bite
Pain scale for insect stings
as melittin, apamin, and MCD peptide. Melittin is the main toxin of bee venom, and it damages red blood cells and white blood cells. Apamin is a neurotoxin
Schmidt_sting_pain_index
US public health issue
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
United States drug overdose death rates and totals over time
United_States_drug_overdose_death_rates_and_totals_over_time
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Cadmium_poisoning
Muscle tenderness after eating quail
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Coturnism
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Zinc_toxicity
Plant that produces swainsonine
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Locoweed
Academic area of substances harmful to living organisms
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Toxicology
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Shellfish_poisoning
Necrotising sore caused by some spider bites
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Loxoscelism
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Tricyclic antidepressant overdose
Tricyclic_antidepressant_overdose
Harmful effects from ingestion of toxic substances present in a mushroom
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Mushroom_poisoning
Syndrome of shellfish poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Paralytic_shellfish_poisoning
Toxicity due to excessive consumption of opiates
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Opioid_overdose
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Hypervitaminosis
Type of metal poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Iron_poisoning
Syndrome marked by sensory neuropathy induced by excess vitamin B6
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Megavitamin-B6_syndrome
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Lithium_toxicity
Protein subfamily of calcium-activated potassium channels
channels (SK1-SK3) but not SK4 (IK) are sensitive to blockade by the bee toxin apamin, and the scorpion venoms tamapin and charybdotoxin (ChTx), all via competitive
SK_channel
Condition in which there are elevated levels of the fluoride ion in the body
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Fluoride_toxicity
Medical condition caused by eating certain legumes of the genus Lathyrus
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Lathyrism
Nontoxic or minimally toxic gas which can displace oxygen in breathing air
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Asphyxiant_gas
Foodborne illness that typically results from eating spoiled fish
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Scombroid_food_poisoning
Type of poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Aluminium_phosphide_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Benzodiazepine_overdose
Syndrome of shellfish poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Amnesic_shellfish_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Epidemic_dropsy
Toxicity from too much ethylene glycol
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Ethylene_glycol_poisoning
Foodborne illness
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Ciguatera_fish_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Cinchonism
Illness from a Latrodectus spider bite
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Latrodectism
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Acute_beryllium_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Digoxin_toxicity
Neurological disease of humans, caused by eating certain legumes of the genus Lathyrus
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Neurolathyrism
Cardiac arrest deaths in China
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Yunnan_sudden_death_syndrome
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
History_of_poison
Polyatomic ion (N(C2H5)4, charge +1)
805-809. D. G. Lang and A. K. Ritchie (1990. "Tetraethylammonium blockade of apamin-sensitive and insensitive Ca2+-activated K+ channels in a pituitary cell
Tetraethylammonium
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Salicylate_sensitivity
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Tick_paralysis
Snake toxin
the 125I-apamin acceptor-binding sites of the rat synaptosomal membranes (Ki = 1.45±0.22 nM) and blocks affinity-labeling of a 33-kDa 125I-apamin-binding
Taicatoxin
Chemical, often household, breathed in to cause intoxication
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Inhalant
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Manganese_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Toluene_toxicity
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
List_of_types_of_poison
Pesticide classification system
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Toxicity_class
Hallucination caused by eating certain species of fish
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Ichthyoallyeinotoxism
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
List_of_poisonous_plants
Scorpion toxin
shows similarity in its physiological activity and binding specificity to apamin, but both toxins show no structural similarity. Scyllatoxin blocks the slow
Scyllatoxin
Class of organic compounds
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Alcohol_(chemistry)
Toxic effect of pesticides
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Organophosphate_poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
List of ICD-9 codes 800–999: injury and poisoning
List_of_ICD-9_codes_800–999:_injury_and_poisoning
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Tin_poisoning
Several medications that disrupt movement of K+ ions
calcium-activated potassium channel blockers include: Charybdotoxin Iberiotoxin Apamin Kaliotoxin, Lolitrem, BKCa-specific GAL-021 Ethanol (alcohol) Examples of
Potassium_channel_blocker
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Animal_lead_poisoning
Species of scorpion
"Characterization of four toxins from Buthus martensi scorpion venom, which act on apamin-sensitive Ca2+-activated K+ channels". European Journal of Biochemistry
Olivierus_martensii
Syndrome of shellfish poisoning
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Neurotoxic shellfish poisoning
Neurotoxic_shellfish_poisoning
Ion channel that selectively passes K+
PMC 1262182. PMID 1384740. Stocker M, Krause M, Pedarzani P (April 1999). "An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons". Proceedings
Potassium_channel
Medical specialty
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Medical_toxicology
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Sulfuric_acid_poisoning
22-amino acid residue peptide
(Megabombus pennsylvanicus) venom. In addition to MCD peptide, melittin and apamin have also been identified in this venom and are also described as voltage-dependent
MCD_peptide
Medical condition
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Haff_disease
Toxic substance
Batroxobin Arthropods Arthropod bites and stings Bee sting / Bee venom Apamin Melittin Scorpion venom Charybdotoxin spider venom Latrotoxin / Latrodectism
Toxicant
Laraba-Djebari (2009). "Characterization of PO1 a new peptide ligand of the apamin-sensitive Ca2+ activated K+ channel". International Journal of Peptide and
OSK3
Protein-coding gene in the species Homo sapiens
S2CID 8290401. Jäger H, Adelman JP, Grissmer S (2000). "SK2 encodes the apamin-sensitive Ca2+-activated K+ channels in the human leukemic T cell line,
KCNN2
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