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Protein
AlkB (Alkylation B) is a protein found in E. coli, induced during an adaptive response and involved in the direct reversal of alkylation damage. AlkB
AlkB
Bacterial DNA damage response pathway
coli. The E. coli adaptive response constitutes four genes: ada, alkA, alkB, and aidB, each one working in specific residues, all regulated by the E
Adaptive_response
Protein-coding gene in the species Homo sapiens
AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase is a protein that in humans is encoded by the ALKBH3 gene. The Escherichia coli AlkB protein
AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
AlkB_homolog_3,_alpha-ketoglutarate-dependent_dioxygenase
Protein-coding gene in the species Homo sapiens
Biotechnology Information, U.S. National Library of Medicine. "Entrez Gene: AlkB homolog 5, RNA demethylase". Retrieved 2017-07-27. Thalhammer A, Bencokova
AlkB homolog 5, RNA demethylase
AlkB_homolog_5,_RNA_demethylase
Protein-coding gene in the species Homo sapiens
encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has
FTO_gene
Damage in DNA which occurs naturally
Direct reversal (MGMT and AlkB) 6-O-methylguanine is reversed to guanine by MGMT, some other methylated bases are demethylated by AlkB accurate Translesion
DNA damage (naturally occurring)
DNA_damage_(naturally_occurring)
Enzyme
omega-hydroxylase, fatty acid omega-hydroxylase, alkane monooxygenase, 1-hydroxylase, AlkB, and alkane hydroxylase. It contains a diiron non-heme active site. Recently
Alkane_1-monooxygenase
alkylated DNA repair protein, alpha-ketoglutarate-dependent dioxygenase ABH1, alkB (gene)) is an enzyme with systematic name methyl DNA-base, 2-oxoglutarate:oxygen
DNA_oxidative_demethylase
Mammalian protein found in Homo sapiens
two known PCNA-interacting motifs PCNA-interacting peptide (PIP) box and AlkB homologue 2 PCNA interacting motif (APIM). Proteins binding to PCNA via the
Proliferating cell nuclear antigen
Proliferating_cell_nuclear_antigen
Protein-coding gene in the species Homo sapiens
AlkB homolog 1, histone H2A dioxygenase is a protein that in humans is encoded by the ALKBH1 gene. This gene encodes a homolog to the E. coli alkB gene
AlkB homolog 1, histone H2A dioxygenase
AlkB_homolog_1,_histone_H2A_dioxygenase
Family of viruses
tandem. Pretty interesting sweet potato potyviral ORF (PISPO), alkylation B (AlkB), and inosine triphosphate pyrophosphatase (known as ITPase or HAM1) are
Potyviridae
Organisms capable of living in extreme environments
species have demonstrated higher gene expression for the alkane mono-oxygenase alkB at temperatures exceeding 60 °C (140 °F).[citation needed] The expression
Extremophile
Brothel village in Bangladesh
pictures reveal the hellish life of a 200-year-old brothel in Bangladesh]. ALKB Media (in Bengali). 10 May 2018. Retrieved 13 July 2020.[permanent dead link]
Kandapara
Class of enzymes
in many biosynthetic and metabolic pathways; for example, in E. coli, the AlkB enzyme is associated with the repair of damaged DNA. In plants, αKG-dependent
Alpha-ketoglutarate-dependent hydroxylases
Alpha-ketoglutarate-dependent_hydroxylases
Escherichia coli adaptive response protein
mutagenic. The Ada response includes the expression of four genes: ada, alkA, alkB, and aidB. The product of ada gene, the Ada protein, is an activator of transcription
Ada_regulon
Swedish-British scientist
Lindahl, T; Sedgwick, B (2002). "Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage". Nature. 419 (6903): 174–8. Bibcode:2002Natur
Tomas_Lindahl
Species of virus
Replicase-associated proteins, methyltransferase, helicase, and RdRp Also contains AlkB domain and codes for Fe2+ coordination motifs and residues ORF2 376 42kDa
Grapevine_Pinot_gris_virus
Human chromosome
protein SP-10 AKIP1: A kinase interacting protein 1 ALKBH3 encoding protein AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase AMOTL1: angiomotin-like
Chromosome_11
Enzyme
Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD (May 2010). "Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification
TRNA (carboxymethyluridine34-5-O)-methyltransferase
TRNA_(carboxymethyluridine34-5-O)-methyltransferase
Danish pharmaceutical company
rights to ALK's SLIT-tablets in North America to revert to ALK from MSD (OMX:ALKB)". 2016-08-17. Archived from the original on 2016-08-17. Retrieved 2023-03-01
ALK-Abelló
Species of bacterium
also contains enzyme systems involved in hydrocarbon degradation, including AlkB, CYP153, and AlmA, which can be used in biocatalysis to transform hydrocarbon-based
Alcanivorax_dieselolei
Chemical compound
form 1,N6-ethanoadenine. Escherichia coli can fix these modifications using AlkB protein. Another way to produce it is via cyclisation of N6-hydroxyethyladenine
1,N6-Ethanoadenine
Modification in mRNA, DNA
revitalized the interests in the study of m6A. A second m6A demethylase alkB homolog 5 (ALKBH5) was later discovered as well. The biological functions
N6-Methyladenosine
of a superfamily of 2OG-Fe(II) dioxygenase, along with DNA repair protein AlkB, and disease resistant EGL-9. The enzyme was found to be a type of hydroxylases
Leprecan
Class of enzymes
5'-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1)". Biochem J. 452 (3): 509–18. doi:10.1042/BJ20121908. PMC 4126167
DNA-(apurinic or apyrimidinic site) lyase
DNA-(apurinic_or_apyrimidinic_site)_lyase
Protein family
(17 April 2023). "Structure and mechanism of the alkane-oxidizing enzyme AlkB". Nature Communications. 14 (1): 2180. Bibcode:2023NatCo..14.2180G. doi:10
Fatty_acid_desaturase
Class of enzymes
adulthood. In DNA repair, the Fe (II)/2-oxoglutarate-dependent dioxygenase AlkB, functions in the oxidative removal of alkylation damage to DNA. Failure
Dioxygenase
Species of bacterium
nucleotide fragment of the alkane hydroxylase gene alkB, which was amplified from the strand W11-5T. The gene alkB is a protein that is produced by A. pacificus
Alcanivorax_pacificus
Technique for the investigation of nucleic acids and its modifications
(6 December 2019). "NAIL-MS reveals the repair of 2-methylthiocytidine by AlkB in E. coli". Nature Communications. 10 (1): 5600. Bibcode:2019NatCo..10.5600R
NAIL-MS
Genus of positive-strand RNA viruses in the family Potyviridae
additional proteins or protein domains, such as P1-PISPO, Alkylation B (AlkB), and inosine triphosphate pyrophosphatase (known as ITPase or HAM1). Such
Potyvirus
quantitation by deep sequencing, which can be overcome by enzyme (such as PNK and AlkB) pre-treatment. Depending on the purpose of the analysis, RNA-seq can be
Small_RNA_sequencing
Protein found in humans
Many associated diseases ALKBH7 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial Validated 2 hybrid A protein hydroxylase and isrequired
Chromosome 20 open reading frame 85
Chromosome_20_open_reading_frame_85
ALKB
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