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Medication class with multiple uses
Beta blockers, also spelled β-blockers and also sometimes known as β-adrenergic receptor antagonists, are a class of medications predominantly used to
Beta_blocker
Pertaining to adrenaline or noradrenaline, or their receptors
Adrenergic means "working on adrenaline (epinephrine) or noradrenaline (norepinephrine)" (or on their receptors). When not further qualified, it is usually
Adrenergic
Class of G protein-coupled receptors
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)
Adrenergic_receptor
Protein family
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists
Alpha-2_adrenergic_receptor
G protein-coupled receptor
The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists
Alpha-1_adrenergic_receptor
Class of drugs
Alpha-adrenergic agonists are a class of sympathetic agents that selectively stimulate alpha adrenergic receptors. The alpha-adrenergic receptor has two
Alpha-adrenergic_agonist
Type of drug
An adrenergic antagonist is a drug that inhibits the function of adrenergic receptors. There are five adrenergic receptors, which are divided into two
Adrenergic_antagonist
Mammalian protein found in humans
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline)
Beta-2_adrenergic_receptor
Substance that mimics effects of catecholamines
of the catecholamines Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of
Sympathomimetic_drug
Drug that stimulates a response from the adrenergic receptors
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2
Adrenergic_agonist
Class of pharmacological agents
antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha-blockers were used as
Alpha_blocker
Sudden increase in adrenaline and noradrenaline in the blood
An adrenergic storm is a sudden and dramatic increase in serum levels of the catecholamines adrenaline and noradrenaline (also known as epinephrine and
Adrenergic_storm
Protein-coding gene in the species Homo sapiens
The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2-adrenergic receptor, and also denotes the human gene encoding it.
Alpha-2A_adrenergic_receptor
Antihypertensive drug
and depression. Prazosin is a non-selective inverse agonist of the α1-adrenergic receptors. It works to decrease blood pressure by dilating blood vessels
Prazosin
A Beta-2 adrenergic antagonist (β2-adrenoceptor antagonist) is an adrenergic antagonist which blocks the beta-2 adrenergic receptors of cells, with either
Beta-2_adrenergic_antagonist
Medications that increase norepinephrine
inhibitor (NRI), also known as a noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor, is a type of drug that acts as a reuptake inhibitor
Norepinephrine reuptake inhibitor
Norepinephrine_reuptake_inhibitor
Part of the autonomic nervous system that stimulates fight-or-flight responses
stimulus, the postganglionic neurons release norepinephrine, which activates adrenergic receptors that are present on the peripheral target tissues. The activation
Sympathetic_nervous_system
Compounds that bind to and activate adrenergic beta-2 receptors
Beta2-adrenergic agonists, also known as adrenergic β2 receptor agonists, are a class of drugs that act on the β2 adrenergic receptor. Like other β adrenergic
Beta2-adrenergic_agonist
Mammalian protein found in Homo sapiens
The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. Actions
Beta-3_adrenergic_receptor
Protein-coding gene in the species Homo sapiens
adrenergic receptor (β1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors
Beta-1_adrenergic_receptor
Protein-coding gene in the species Homo sapiens
alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor
Alpha-1A_adrenergic_receptor
Medication used to treat high blood pressure
during breastfeeding. It works by blocking the activation of β- and α-adrenergic receptors. Labetalol was patented in 1966 and came into medical use in
Labetalol
Drug which widens the lung airways
symptoms. The three types of prescription bronchodilating drugs are beta-2 adrenergic agonists (short- and long-acting), anticholinergics (short- and long-acting)
Bronchodilator
Protein-coding gene in the species Homo sapiens
The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor. It is a subtype of the adrenergic receptor family. The human gene
Alpha-2B_adrenergic_receptor
A Beta-3 adrenergic antagonist (β3-adrenoceptor antagonist) is an adrenergic antagonist which blocks the Beta-3 adrenergic receptors of cells, with either
Beta-3_adrenergic_antagonist
An adrenergic nerve fibre is a neuron for which the neurotransmitter is either adrenaline (epinephrine), noradrenaline or dopamine. These neurotransmitters
Adrenergic_nerve_fibre
Primary cell of the nervous system
A neuron (American English), neurone (British English), or nerve cell, is a cell that is excitable, firing electric signals called action potentials. Neurons
Neuron
Blood pressure medication
variety of targets including the β1-adrenergic receptor, β2-adrenergic receptor, α1-adrenergic receptor, α2-adrenergic receptor, 5-HT1A receptor, 5-HT2 receptor
Carvedilol
Medications that relax muscles of the airways
Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing
Beta-adrenergic_agonist
Veterinary anesthetic, sedative and analgesic
Xylazine is a structural analog of clonidine and an α2-adrenergic receptor agonist, sold under many trade names worldwide, most notably the Bayer brand
Xylazine
Class of pharmacological agents
adrenergic receptor agonist or β3-adrenoceptor agonist, also known as β3-AR agonist, are a class of medicine that bind selectively to β3-adrenergic receptors
Beta3-adrenergic_agonist
Protein-coding gene in the species Homo sapiens
The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding
Alpha-2C_adrenergic_receptor
Type of medication
norepinephrine. They are primarily postsynaptic adrenergic receptor antagonists (alpha and beta adrenergic receptor antagonists, or "blockers"), inhibiting
Sympatholytic
Beta blocker drug
be safe. It is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was patented in 1962 and approved for medical use
Propranolol
Enzyme
enzymology, a beta-adrenergic-receptor kinase (EC 2.7.11.15) is an enzyme that catalyzes the chemical reaction: ATP + [beta-adrenergic receptor] ⇌ {\displaystyle
Beta-adrenergic-receptor kinase
Beta-adrenergic-receptor_kinase
Hormone and medication
Sympathetic nerve receptors are classified as adrenergic, based on their responsiveness to adrenaline. The term "adrenergic" is often misinterpreted in that the
Adrenaline
Antidepressant medication
safe. How it works is not clear, but it may involve blocking certain adrenergic and serotonin receptors. Chemically, it is a tetracyclic antidepressant
Mirtazapine
Class of compounds
alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors
Alpha-1_blocker
β1-Adrenergic receptor agonists, also known as beta-1 agonists, are a class of drugs that bind selectively to the β1-adrenergic receptor. As a result,
Beta1-adrenergic_agonist
Class of drugs
Adrenergic neurone blockers, commonly known as adrenergic antagonists, are a group of drugs that inhibit the sympathetic nervous system by blocking the
Adrenergic_neuron_blockers
Muscle relaxant medication
inhibit serotonin and norepinephrine reuptake and to block serotonin, adrenergic, histamine, and muscarinic acetylcholine receptors. Chemically, it is
Cyclobenzaprine
Medical condition
Adrenergic urticaria is a skin condition characterized by an eruption consisting of small (1-5mm) red macules and papules with a pale halo, appearing within
Adrenergic_urticaria
Medication; α-adrenergic antagonist
sold under the brand name Regitine among others, is a non-selective α-adrenergic antagonist. The primary application for phentolamine is for the control
Phentolamine
Medication for slow heart rate
Isoprenaline is a selective agonist of the β-adrenergic receptors, including both the β1- and β2-adrenergic receptors. By activating these receptors, it
Isoprenaline
Catecholaminergic type of drug
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine
Norepinephrine releasing agent
Norepinephrine_releasing_agent
Protein-coding gene in humans
The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding
Alpha-1D_adrenergic_receptor
Chemical compound
agonist of the α1-adrenergic receptor. It is a vasoconstrictor and antihypotensive agent. It has also been described as a β1-adrenergic receptor agonist
Etilefrine
Psychoactive species of plant
Cathine is somewhat less understood, being believed to act upon the adrenergic receptors causing the release of epinephrine and norepinephrine. It has
Khat
Protein-coding gene in the species Homo sapiens
The alpha-1B adrenergic receptor (α1B-adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding
Alpha-1B_adrenergic_receptor
Class of antidepressants
drugs used primarily as antidepressants. They act by antagonizing the α2-adrenergic receptor and certain serotonin receptors such as 5-HT2A and 5-HT2C, but
Noradrenergic and specific serotonergic antidepressant
Noradrenergic_and_specific_serotonergic_antidepressant
This is a list of adrenergic drugs. These are pharmaceutical drugs, naturally occurring compounds and other chemicals that influence the function of the
List_of_adrenergic_drugs
Antihypotensive medication
norepinephrine releasing agent and at high doses a α1-adrenergic receptor agonist with some β-adrenergic effect. It is a substituted amphetamine and is closely
Metaraminol
Medication used for high blood pressure and ADHD
blood pressure and urinary problems. It appears to work by activating α2A-adrenergic receptors in the brain, thereby decreasing sympathetic nervous system
Guanfacine
Drug used to treat asthma
as rescue medications for acute asthma attacks include short-acting β2-adrenergic receptor agonists (SABA), short-acting muscarinic antagonists (SAMA),
Anti-asthmatic_agent
Medication for overactive bladder
irregular heart rate, and angioedema. It works by activating the β3 adrenergic receptor in the bladder, resulting in its relaxation. Mirabegron is the
Mirabegron
Adrenergic cell group C1 is a group of cells that show evidence of containing phenylethanolamine N-methyltransferase (PNMT), the enzyme that converts norepinephrine
Adrenergic_cell_group_C1
Chemical compound
Tolazoline is a non-selective competitive α2-adrenergic receptor antagonist. It is a vasodilator that is used to treat spasms of peripheral blood vessels
Tolazoline
Chemical compound
non-selective agonist of the α1-, α2-, and β-adrenergic receptors. It is said to have preferential activity at the α2-adrenergic receptor. Corbadrine is also a metabolite
Corbadrine
Pharmaceutical compound
originally known as MK-467, is an α2-adrenergic receptor antagonist used in veterinary medicine alongside α2-adrenergic receptor agonists to counteract vasoconstriction
Vatinoxan
The adrenergic receptors (or adrenoreceptors) are a class of cell membrane-bound protein receptors throughout the body that are targets of the catecholamines
Adrenergic receptor autoantibodies
Adrenergic_receptor_autoantibodies
Muscle relaxant medication
sold under the brand names Zanaflex and Sirdalud among others, is an α2-adrenergic receptor agonist and muscle relaxant which is used to treat muscle spasticity
Tizanidine
Pharmaceutical compound
ADRIANA is a selective α2B-adrenergic receptor antagonist. It is described as highly selective over the α2A- and α2C-adrenergic receptors. The drug stimulates
ADRIANA
Chemical compound
skeletal muscle, with minimal or no effect on α adrenergic receptors. The pharmacologic effects of β adrenergic agonist drugs, such as orciprenaline, are at
Orciprenaline
Alpha-adrenergic agonist
sold under the brand names Catapres and Kapvay, among others, is an α2-adrenergic receptor agonist, hypotensive, sedative and anxiolytic drug used to treat
Clonidine
Decongestant medication
breastfeeding is safe. Phenylephrine is a selective α1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine
Phenylephrine
Class of chemical compounds
J.; Denoroy, L.; Kopp, N.; Ulrich, J.; Maeda, T.; Jouvet, M. (1985). "Adrenergic neurons in human brain demonstrated by immunohistochemistry with antibodies
Catecholamine
Drugs blocking alpha-2 adrenergic receptors
subset of the alpha blocker class of drugs and are antagonists to the α2 adrenergic receptor. They are mainly used in research, having found limited clinical
Alpha-2_blocker
Topical decongestant
sympathomimetic, oxymetazoline binds to and activates α1 adrenergic receptors and α2 adrenergic receptors, most notably. In 2022, it was the 305th most
Oxymetazoline
Class of drugs
Adrenergic blocking agents are a class of drugs that exhibit its pharmacological action through inhibiting the action of the sympathetic nervous system
Adrenergic_blocking_agent
Pharmaceutical compound
5-HT2A receptor. The drug is inactive against adrenergic receptors including the α1-, α2-, β1-, and β2-adrenergic receptors. It produces hypotension in rodents
FCE-24379
Class of pharmaceutical drugs
Selective androgen receptor modulators (SARMs) are a class of drugs that selectively activate the androgen receptor in specific tissues, promoting muscle
Selective androgen receptor modulator
Selective_androgen_receptor_modulator
Excessive dilation of the pupil
GABAergic drugs, such as phenibut and GHB. Adrenergic agonists, such as phenylephrine and cyclomydril. Adrenergic agonists may be used if strong mydriasis
Mydriasis
Chemical compound
It is also related to ajmalicine. Corynanthine acts as an α1-adrenergic and α2-adrenergic receptor antagonist with approximately 10-fold selectivity for
Corynanthine
Chemical compound
SR 59230A is a selective antagonist of the beta-3 adrenergic receptor, but was subsequently shown to also act at α1 adrenoceptors at high doses. It has
SR_59230A
Species of flowering plant
source of calabash or gourd curare. Macusine B is an alkaloid inhibitor of adrenergic alpha-receptors and tryptamine receptors that can be isolated from Strychnos
Strychnos_toxifera
Chemical compound
pregnancy and breastfeeding is not recommended. It works by blocking β1-adrenergic receptors in the heart and dilating blood vessels. Nebivolol was patented
Nebivolol
Veterinary medication
sold under the brand name Antisedan among others, is a synthetic α2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic
Atipamezole
Pharmacological term
The rebound effect, also known as the rebound phenomenon, refers to the re-emergence of symptoms that were previously absent or controlled while on medication
Rebound_effect
Chemical compound
parent compound of other drugs like the α-adrenergic receptor antagonist phenoxybenzamine, the α2-adrenergic receptor modulators lofexidine, allyphenyline
Phenoxyethylamine
Chemical compound
blood pressure. Penbutolol is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective
Penbutolol
Group of neurons in the medulla
(adrenaline). Located in the medulla, they are named adrenergic cell group C1, adrenergic cell group C2, and adrenergic cell group C3. Noradrenergic cell groups Smeets
Adrenergic_cell_groups
Beta-1 selective adrenenergic blocker medication used to treat cardiovascular diseases
this cascade, so decreases the adrenergic tone/stimulation of the heart muscle and pacemaker cells. Decreased adrenergic tone shows less contractility
Bisoprolol
Investigational PMS/PMDD drugs
postural orthostatic tachycardia syndrome (POTS) [2] CST-3056 (CuraAX) – α1-adrenergic receptor agonist – orthostatic hypotension [3] [4] REGN-7544 (REGN7544)
List of investigational orthostatic intolerance drugs
List_of_investigational_orthostatic_intolerance_drugs
Abnormally high heart rate after a postural change
against the α1-adrenergic receptor and against the muscarinic acetylcholine M4 receptor. Elevations of autoantibodies targeting the α1-adrenergic receptor have
Postural orthostatic tachycardia syndrome
Postural_orthostatic_tachycardia_syndrome
Pharmaceutical compound
names ODM-105 and ORM-19695), sold under the brand name Tessie, is an α2-adrenergic receptor agonist which is approved for the short-term treatment of fear
Tasipimidine
Chemical compound
latter being the isomer with the pharmacologic effect as an alpha 2- adrenergic agonist. Effects can be reversed using atipamezole. It was developed by
Medetomidine
Psychoactive substance found in plants in the family Apocynaceae
Nalmefene Topiramate AATooltip Adrenergic agonist (Clonidine) Baclofen Phenibut Opioid dependence AATooltip Adrenergic agonist (Clonidine Lofexidine)
Ibogaine
Chemical compound
BRL-37344 is a drug which acts as a selective agonist of the β3 adrenergic receptor, which has been investigated for various biomedical research applications
BRL-37344
Class of heart medication
groups based on their unique mechanisms of action: cardiac glycosides, β-adrenergic agonists, phosphodiesterase III inhibitors, and calcium sensitizers. Certain
Cardiotonic_agent
Adrenergic cell group C2 is a group of cells that label for PNMT, the enzyme that converts norepinephrine to epinephrine (adrenaline); thus, they are regarded
Adrenergic_cell_group_C2
Drug discovery
β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris
Discovery and development of beta-blockers
Discovery_and_development_of_beta-blockers
Chemical compound
and α2-adrenergic receptor antagonist isolated from Rauvolfia verticillata. Its dimer dispegatrine has greater antagonist affinity for α-adrenergic receptors
Spegatrine
Symptoms of low blood sugar (fatigue, moodiness, etc) but without cause
altered mood and cognitive dysfunction, often accompanied by weakness and adrenergic symptoms such as shakiness. The episodes typically occur a few hours after
Idiopathic postprandial syndrome
Idiopathic_postprandial_syndrome
Medication for asthma and COPD
propionate, an inhaled corticosteroid; and salmeterol, a long-acting beta2‑adrenergic agonist. It is used in the management of asthma and chronic obstructive
Fluticasone/salmeterol
Chemical compound
Pafenolol is a beta adrenergic receptor antagonist. Lennernäs, H; Regårdh, CG (1993). "Dose-dependent intestinal absorption and significant intestinal
Pafenolol
Chemical compound
GR50360A) is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent selectivity for this receptor over the α1-adrenergic receptor (2,630-fold)
Fluparoxan
Chemical compound
v t e Adrenergic receptor modulators α1 Agonists 6-FNE Amidephrine Buspirone Cirazoline Corbadrine CST-2140 CST-3056 (CuraAX) Deoxyepinephrine (epinine
Racepinefrine
Reddening of a person's face due to emotion
In a number of trials, he blocked both alpha-adrenergic receptors (with phentolamine) and beta-adrenergic receptors (with propranolol introduced transcutaneously
Blushing
Chemical compound
not cardioselective (i.e., is not selective for the β1-adrenergic receptor over the β2-adrenergic receptor). It has membrane stabilizing activity but no
Butidrine
Compounds that damage or destroy monoaminergic neurons
5-DDM-DOM 5-HIAL RHPP+ RHPTP See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake
Monoamine_neurotoxin
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