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Look up adjuvant in Wiktionary, the free dictionary. In pharmacology, an adjuvant is a drug or other substance, or a combination of substances, that is
Adjuvant
Medical treatment in addition to a primary treatment to maximise effectiveness
Adjuvant therapy, also known as adjunct therapy, adjuvant care, or augmentation therapy, is a therapy that is given in addition to the primary or initial
Adjuvant_therapy
Antigen solution emulsified in mineral oil
adjuvant is a solution of antigen emulsified in mineral oil and used as an immunopotentiator (booster). The complete form, Freund's Complete Adjuvant
Freund's_adjuvant
Pesticide adjuvants are chemicals applied alongside pesticides to enhance the effectiveness of the active ingredient. They are used together with the
Pesticide_adjuvant
Component of vaccines
In immunology, an adjuvant is a substance that increases or modulates the immune response to a vaccine. The word "adjuvant" comes from the Latin word adiuvare
Immunologic_adjuvant
Medication used for other purposes that additionally has analgesic effects
An analgesic adjuvant is a medication that is typically used for indications other than pain control but provides control of pain (analgesia) in some painful
Analgesic_adjuvant
Chemical compound
Squalene is an important ingredient in some vaccine adjuvants: The Novartis and GlaxoSmithKline adjuvants are called MF59 and AS03, respectively. Squalene
Squalene
Cancer of the bile ducts
been totally excised), adjuvant therapy is of uncertain benefit. Both positive and negative results have been reported with adjuvant radiation therapy in
Cholangiocarcinoma
Type of immunoglobulin molecule
Antigen preparation Adjuvant selection and preparation Animal selection Injection process Blood serum extraction An antigen/adjuvant conjugate is injected
Polyclonal_antibodies
Pharmaceutical drug used in cancer treatment
advanced (unresectable or metastatic) melanoma in adults as monotherapy. the adjuvant treatment of adults with Stage III melanoma and lymph node involvement
Pembrolizumab
Hypothesised autoimmune disorder
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), or Shoenfeld's syndrome, is a hypothesised autoimmune disorder proposed by Israeli immunologist
Autoimmune/inflammatory syndrome induced by adjuvants
Autoimmune/inflammatory_syndrome_induced_by_adjuvants
Medical intervention
Chemoradiotherapy (CRT, CRTx, CT-RT) is the combination of chemotherapy and radiotherapy to treat cancer. Synonyms include radiochemotherapy (RCT, RCTx
Chemoradiotherapy
adjuvant to surgery in treating patients with colon cancer. Similarly, the landmark trials of Bernard Fisher, chair of the National Surgical Adjuvant
History of cancer chemotherapy
History_of_cancer_chemotherapy
Medical condition
tests, in place of adjuvant treatment. Before 1970, survival rates from testicular cancer were low. Since the introduction of adjuvant chemotherapy, chiefly
Testicular_cancer
Natural bark extract used in food and medicine
an adjuvant for human vaccines. Novavax uses a highly purified quillaja extract as an adjuvant in its veterinary and human vaccines. The adjuvant, Matrix-M
Quillaia
Species of mushroom
polysaccharide-K, an extract of T. versicolor, is approved in Japan as an adjuvant therapy in cancer treatment, it is not approved in the United States for
Trametes_versicolor
Anticancer medication
12 months of neoadjuvant or adjuvant treatment with platinum-based chemotherapy. Nivolumab is indicated for the adjuvant treatment of melanoma with lymph
Nivolumab
MRNA-based cancer vaccine
massive parallel sequencing of tissue generated from cancer patients. As adjuvant therapy, mRNA-4157 monotherapy and in combination with pembrolizumab have
Intismeran_autogene
Experimental tuberculosis vaccine
of two M. tuberculosis antigens (Mtb32A O07175 and Mtb39A L7N675). The adjuvant part is AS01E, a combination of QS-21, cholesterol, and monophosphoryl
M72/AS01E
Medical condition
after surgery as an adjuvant treatment to prevent recurrence. In most cases, adjuvant treatment is part of the treatment schema. Adjuvant therapy is given
Paget's_disease_of_the_breast
Part of the female reproductive tract
W (January–February 2017). "American Brachytherapy Task Group Report: Adjuvant vaginal brachytherapy for early-stage endometrial cancer: A comprehensive
Vagina
Component of the innate immune system
speculation that 2'-3' cGAMP could be used as a more efficient and direct adjuvant than DNA to induce immune responses. Naturally occurring variations in
CGAS–STING cytosolic DNA sensing pathway
CGAS–STING_cytosolic_DNA_sensing_pathway
ALK inhibitor for treatment of non-small-cell lung cancer
alectinib for adjuvant treatment of resected non‑small cell lung cancer (NSCLC). In June 2024, the EU approved alectinib as an adjuvant treatment for
Alectinib
Squalene-based adjuvant
MF59 is an immunologic adjuvant that uses squalene. It is Novartis' proprietary adjuvant that is added to influenza vaccines to help stimulate the human
MF59
Chemical compound
the dendritic cell to activate a peptide-specific T cell response. This adjuvant acts through this cellular interaction, rather than through classic pattern
Α-Galactosylceramide
Type of endocrine gland cancer
trials are often conducted to assess novel adjuvant therapies. The role of radiotherapy as an auxiliary (adjuvant) treatment after potentially curative surgery
Pancreatic_cancer
Pharmaceutical compound
Zidebactam (WCK-5107) is an antibiotic adjuvant drug which acts as a beta-lactamase inhibitor, preventing the breakdown of other antibiotic drugs. Cefepime
Zidebactam
Vaccine adjuvant
Matrix-M is a vaccine adjuvant, a substance that is added to various vaccines to stimulate the immune response. It was patented in 2020 by Novavax and
Matrix-M
Pharmaceutical drug
Pegylated interferon alfa-2b is a drug used to treat melanoma, as an adjuvant therapy to surgery. Also used to treat hepatitis C (typically, in combination
Peginterferon_alfa-2b
General anesthesia method
preparation and maintenance. The doses for intravenous sedative-hypnotic and adjuvant agents vary individually. Pharmacodynamic and pharmacokinetic factors need
Total_intravenous_anaesthesia
Medication used to treat cancer
been used for adjuvant therapy of stage 1 seminomatous testicular cancer. Research has indicated that it is not less effective than adjuvant radiotherapy
Carboplatin
Combination of adjuvants
Adjuvant System 04 or AS04 is a trade name for a combination of adjuvants used in various vaccine products by GlaxoSmithKline, in particular the Fendrix
AS04
Antigen/epitope that induce immune response
The immune response can be enhanced using an adjuvant injected together with the immunogen. An adjuvant (from Latin adiuvare – to help) is any substance
Immunogen
Aggressive type of brain cancer
with newly diagnosed glioblastoma who are reasonably fit, concurrent and adjuvant chemoradiotherapy gives the best overall survival but is associated with
Glioblastoma
Vaccines against the bacterium Bacillus anthracis
in many countries around the world, most of which use 34F2 with saponin adjuvant. Anthrax vaccines were developed in the Soviet Union in the 1930s and available
Anthrax_vaccine
Plant extract
QS-21 is a purified plant extract used as a vaccine adjuvant. It is derived from the soap bark tree (Quillaja saponaria), which is native to the countries
QS-21
Species of plant
also considered to have adjuvant properties for vaccine solutions, and have been used for this purpose since 2017. QS21 adjuvant is a saponin (triterpenoid
Quillaja_saponaria
Peptide in Homo sapiens
treatments for short bowel syndrome, Crohn's disease, osteoporosis and as adjuvant therapy during cancer chemotherapy. GLP-2 has an antidepressant effect
Glucagon-like_peptide-2
HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a complex between alpha-lactalbumin and oleic acid that has been shown in cell culture experiments
HAMLET_(protein_complex)
American biotechnology company
Novavax develops proprietary immune-stimulating saponin-based immunologic adjuvants at a wholly owned Swedish subsidiary, Novavax AB. One of these, Matrix-M
Novavax
Cancer of the throat
latter. The addition of another modality of treatment is referred to as adjuvant (literally helping) therapy, compared to its use as the initial (primary)
HPV-positive oropharyngeal cancer
HPV-positive_oropharyngeal_cancer
Biotechnology company
checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly
Agenus
Individualised mRNA cancer vaccine
investigational mRNA vaccine being developed jointly by BioNTech and Genentech as an adjuvant therapy in cancer treatment to prevent cancer recurrence following surgery
Autogene_cevumeran
Protein-bound polysaccharide
mycelium of Trametes versicolor. Although PSK is approved in Japan as an adjuvant therapy in cancer treatment, it is not approved in the United States for
Polysaccharide-K
Chemical compound
samples can appear as a yellow or even brown liquid. It is used as an adjuvant component of pesticide formulations for synergy. That is, despite having
Piperonyl_butoxide
Peptide that consists of four amino acids
A novel vaccine adjuvant that's purpose is to evoke both humoral and cellular immune responses was reported. This vaccine adjuvant was found from a supramolecular
Tetrapeptide
Preliminary cancer therapy that precedes a necessary second treatment
surgery, are precluded, and the patient is rendered unfit for anesthetic. Adjuvant chemotherapy Chemotherapy Remiszewski, Piotr; Filipek, Kinga; Pisklak,
Neoadjuvant_therapy
Therapy using ionizing radiation, usually to treat cancer
body, and have not spread to other parts. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary
Radiation_therapy
Blistering autoimmune diseases
of corticosteroids may require the use of so-called steroid-sparing or adjuvant drugs. One of the most dangerous side effects of high-dosage steroid treatments
Pemphigus
Medical condition
endothelial growth factor (VEGF), bevacizumab, has shown promising result as an adjuvant therapy in the management of recurrent respiratory papillomatosis. Although
Laryngeal_papillomatosis
Mood disorder
as amphetamine and modafinil, may be effective in the short term, or as adjuvant therapy. Also, it is suggested that folate supplements may have a role
Major_depressive_disorder
Vaccine against hantavirus infections
Immunization: Vaccines, Vaccination, Infection, Inoculation (J07) Development Adjuvants Vaccine ingredients list Mathematical modelling Storage Timeline Trials
Hantavirus_vaccine
Vaccine against COVID-19
resulting inactivated viruses are then mixed with the aluminium-based adjuvant Alhydroxiquim-II. The vaccine is produced with Bharat Biotech's in-house
Covaxin
Aggressive and rare cancer
Talarico F, Iusco D, Negri L, Belinelli D: Combined resection and multi-agent adjuvant chemotherapy for intra-abdominal desmoplastic small round cell tumour:
Desmoplastic small-round-cell tumor
Desmoplastic_small-round-cell_tumor
Malignant tumor of oil glands in the skin
invasion. Data on the role of adjuvant radiation therapy in the treatment of SGc is scarce, however, and recurrence following adjuvant radiation therapy has been
Sebaceous_carcinoma
Any type of epithelial lung cancer other than small-cell lung carcinoma
increasingly both preoperatively (neoadjuvant chemotherapy) and postoperatively (adjuvant chemotherapy). The most common types of non-small-cell lung cancer are
Non-small-cell_lung_cancer
Guideline for the use of drugs in the management of pain
drugs such as paracetamol (acetaminophen) or aspirin, with or without "adjuvants" such as non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2
Pain_ladder
Non-active ingredient in a medication
vehicle-controlled studies. Adjuvants are added to vaccines to enhance or modify the immune system response to an immunization. An adjuvant may stimulate the immune
Excipient
Chemical compound
arthritis-inducing Freund’s adjuvant. After 20 days, both groups had no visible sign of arthritis. Then, a group was re-injected with the adjuvant while the other
Cetyl_myristoleate
Chemical compound
wheat and barley. Flamprop formulations have long needed an oil based adjuvant for good performance. Originally, this was 30 to 36% naphthenic and 9 to
Flamprop
Medication
taxpayer-funded public health system, such as New Zealand, chose to fund limited adjuvant therapy. However, subsequently New Zealand has revised its policy and now
Trastuzumab
Vaccine against COVID-19
a saponin-based adjuvant named Matrix-M. Matrix-M adjuvant source is purified from Quillaja Saponaria Molina Tree. Matrix-M adjuvant is combined with
Novavax_COVID-19_vaccine
Index for breast cancer surgery
nodes; and the grade of the tumour. It is calculated to select patients for adjuvant treatment. The index is calculated using the formula: NPI = [0.2 x S] +
Nottingham_Prognostic_Index
Polymer in bacterial cell walls
vaccine or as adjuvant alone. MDP, which is the basic unit of peptidoglycan, was initially used as the active component of Freund's adjuvant. Peptidoglycan
Peptidoglycan
Class of drugs
would increase. Ongoing areas of clinical research include optimizing adjuvant hormonal therapy in postmenopausal women with breast cancer. Tamoxifen
Aromatase_inhibitor
Medical condition
Liver transplant may be used where partial resection is not an option, and adjuvant chemoradiation may benefit some cases. 60% of cholangiocarcinomas form
Liver_cancer
Recurrent inflammation and clotting of blood vessels in the hands and feet
above-knee amputation is rarely required. Streptokinase has been proposed as adjuvant therapy in some cases. Despite the clear presence of inflammation in this
Thromboangiitis_obliterans
Organism belonging to kingdom Fungi
Krestin), a chemical derived from Trametes versicolor, is an approved adjuvant for cancer therapy. Certain mushrooms are used as supposed therapeutics
Fungus
Type of malignant tumor found in animals
containing aluminum adjuvant, as the adjuvant, by design, increases inflmmation to stengthen the immune response. Particles of aluminum adjuvant have been discovered
Vaccine-associated_sarcoma
Vaccine using a killed version of a disease pathogen
weaker response by the immune system than live pathogens, immunologic adjuvants and multiple "booster" injections may be required in some vaccines to
Inactivated_vaccine
Process of determining the extent of cancer spread
treatment (particularly the need for pre-operative therapy and/or for adjuvant treatment, the extent of surgery) is generally based on this parameter
Cancer_staging
Vaccine adjuvant now being trialed as an Alzheimer's vaccine at Brigham and Women's
Protollin is a drug initially formulated as a vaccine adjuvant. It is composed of lipopolysaccharides derived from the Shigella flexneri or Pleisiomonas
Protollin
Breast cancer drug
Letrozole is indicated for adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer; extended adjuvant treatment of postmenopausal
Letrozole
Chemical compound
prolong disease free survival.[unreliable medical source?] The Standard adjuvant therapy is a combination of cyclophosphamide, methotrexate and fluorouracil
Epirubicin
Chemical compound
hydroxide is included as an adjuvant in some vaccines (e.g. anthrax vaccine). One of the well-known brands of aluminium hydroxide adjuvant is Alhydrogel, made
Aluminium_hydroxide
Vaccine to prevent shingles
immunological adjuvant. The antigen is a purified truncated form of the glycoprotein, expressed in Chinese hamster ovary cells. The AS01B adjuvant suspension
Zoster_vaccine
American biotech company
intradermal delivery and the use of the heat labile toxin as an adjuvant and the adjuvant patch. Transdermal patch Frech, SA; Dupont, HL; Bourgeois, AL;
IOMAI
Family of double sulfate salts of aluminium
word alum may also refer to aluminium hydroxide gel used as a vaccine adjuvant. The western desert of Egypt was a major source of alum substitutes in
Alum
American immunologist
was a Hungarian born American immunologist, most famous for the Freund's adjuvant. According to the Journal of Immunology, "Jules (Julius) Freund studied
Jules_T._Freund
Form of kidney cancer
this is often short-lived with more tumours and growths developing later. Adjuvant therapy, which refers to therapy given after a primary surgery, had for
Renal_cell_carcinoma
Class of anticancer drugs
multi-regional study 674 patients with resected high-risk melanoma receiving adjuvant immune checkpoint blockade, pre-treatment gut bacterial markers were associated
PD-1_and_PD-L1_inhibitors
Vaccine ingredient
AS03 (for "Adjuvant System 03") is the trade name for a squalene-based immunologic adjuvant used in various vaccine products by GlaxoSmithKline (GSK).
AS03
Flu vaccine
derived from A/California/7/2009 (H1N1), the vaccine contains an immunologic adjuvant AS03 which consists of DL-α-tocopherol (vitamin E), squalene and polysorbate
Pandemrix
Species of bacterium
Streptococcus thermophilus, formerly known as Streptococcus salivarius subsp. thermophilus, is a gram-positive bacterium and fermentative facultative anaerobe
Streptococcus_thermophilus
Inflammation of membranes around the brain
addition to the primary therapies of antibiotics and corticosteroids, other adjuvant therapies are under development or are sometimes used to improve survival
Meningitis
Group of chemical substances used as poison
Curare (/kʊˈrɑːri/ or /kjʊˈrɑːri/; kuu-RAH-ree or kyuu-RAH-ree) is a common name for various alkaloid arrow poisons originating from plant extracts. Used
Curare
Medication
Immunization: Vaccines, Vaccination, Infection, Inoculation (J07) Development Adjuvants Vaccine ingredients list Mathematical modelling Storage Timeline Trials
Chikungunya_vaccine
Medical intervention
region of 40–45 °C (104–113 °F). Hyperthermia is usually applied as an adjuvant to radiotherapy or chemotherapy, to which it works as a sensitizer, in
Hyperthermia_therapy
Nonsteroidal anti-inflammatory drug
Derry CJ, Derry S, Moore RA (December 2014). "Caffeine as an analgesic adjuvant for acute pain in adults". The Cochrane Database of Systematic Reviews
Aspirin
Small collection of cancer cells that has spread to another part of the body
cytotoxic chemotherapies may not be as useful. Therefore, adjuvant chemotherapy and adjuvant radiation therapy[clarification needed] are more effective
Micrometastasis
Breast cancer medication
level, and slows the growth of cancers. Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early
Exemestane
Chemical compound
detected by an FDA-approved test, following recurrence on or after completing adjuvant endocrine therapy. The most common adverse reactions include gastrointestinal
Inavolisib
Chemical compound
Amifostine (ethiofos) is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents. It is marketed
Amifostine
Vaccines to prevent tuberculosis
of two fused tuberculosis bacillus protein antigens together with the adjuvant AS01. Promising phase II trials were completed in 2018 and phase III trials
Tuberculosis_vaccines
Pharmaceutical drug
chemotherapy or have disease progression within twelve months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy. Adults with unresectable
Durvalumab
Surgical removal of trabecular tissue in the eye
inhibiting fibroblast proliferation. Alternatively, non-chemotherapeutic adjuvants can be implemented to prevent super scarring by wound modulation, such
Trabeculectomy
Selective estrogen receptor modulator
reduction of contralateral (in the opposite breast) cancer. Five years of adjuvant tamoxifen treatment significantly lowers the 15-year risk of breast cancer
Tamoxifen
Sheena; Moore, R Andrew (11 December 2014). "Caffeine as an analgesic adjuvant for acute pain in adults". Cochrane Database of Systematic Reviews. 12
List of paracetamol brand names
List_of_paracetamol_brand_names
Cancerous tumor of the developing eye
approach using chemotherapy to initially reduce the size of the tumor, and adjuvant focal treatments, such as transpupillary thermotherapy, to control the
Retinoblastoma
American researcher
discovery and development of adjuvants, immune therapies, and vaccines. He has developed vaccines, diagnostics, adjuvants and immune-therapeutics and patented
Darrick_Carter
ADJUVANT
ADJUVANT
ADJUVANT
ADJUVANT
Boy/Male
Christian & English(British/American/Australian)
Valley Estate
Boy/Male
Anglo, British, English
Name of a King
Boy/Male
Hindu
Pure
Boy/Male
British, English
Golden Friend
Girl/Female
Latin
Protector.
Girl/Female
Assamese, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Tamil, Telugu
Different; Unique
Girl/Female
English
Originally the ancient duchy of Bretagne in France. Celtic Bretons emigrated from France to...
Boy/Male
Hindu, Indian
God
Boy/Male
Tamil
Kautilya | கௌடிலà¯à®¯
Name of Chanakya, Strategic, Shrewd, Acute
Girl/Female
Spanish American German
Beautiful; pretty rose.
ADJUVANT
ADJUVANT
ADJUVANT
ADJUVANT
ADJUVANT
a.
Helping; helpful; assisting.
n.
A substance added to an immunogenic agent to enhance the production of antibodies.
n.
A substance added to a formulation of a drug which enhances the effect of the active ingredient.
n.
An ingredient, in a prescription, which aids or modifies the action of the principal ingredient.
n.
An assistant.
n.
An adjuvant.