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Protein-coding gene in the species Homo sapiens
Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene. TFE3, a member of the helix-loop-helix family of transcription factors,
TFE3
Protein-coding gene
(GPNMB), a transcriptional target of TFE3. Subsequently, FLCN was shown to regulate TFE3 activity by sequestering TFE3 in the cytoplasm where it is transcriptionally
Folliculin
Mammalian protein found in humans
normal cell precursors. MITF, together with transcription factor EB (TFEB), TFE3 and TFEC, belong to a subfamily of related bHLHZip proteins, termed the MiT-TFE
Microphthalmia-associated transcription factor
Microphthalmia-associated_transcription_factor
Medical condition
17. This translocation creates a fusion between two genes named ASPL and TFE3, which results in the formation of an aberrant protein (termed fusion protein)
Alveolar_soft_part_sarcoma
Protein-coding gene in the species Homo sapiens
rearrangement with transcription factor TFE3 gene, creating an aberrant gene that is a stronger transcriptional activator than TFE3 alone. This fusion oncogene encodes
ASPSCR1
Protein-coding gene in the species Homo sapiens
of the cancer. As a result of the translocation, the transcription factor TFE3 on the X chromosome becomes fused to this gene on chromosome 1. The fused
PRCC_(gene)
Protein structural motif
SREBF1; SREBF2; TAL1; TAL2; TCF12; TCF15; TCF21; TCF3; TCF4; TCFL5; TFAP4; TFE3; TFEB; TFEC; TWIST1; TWIST2; USF1; USF2. Basic helix-loop-helix leucine zipper
Basic_helix–loop–helix
Protein-coding gene in the species Homo sapiens
"RBM10-TFE3 Renal Cell Carcinoma: A Potential Diagnostic Pitfall Due to Cryptic Intrachromosomal Xp11.2 Inversion Resulting in False-negative TFE3 FISH"
RBM10
Form of kidney cancer
eosinophilic cells Chromosomal translocation involving TFE3 gene on Xp11.2 resulting in overexpression of the TFE3 protein Present at advanced stage, but with indolent
Renal_cell_carcinoma
Inferred motif from similar protein – In vivo/Misc source [945] DYYTCSCGCYMWWY TFE3 ENSG00000068323 bHLH Known motif – High-throughput in vitro [946] RKCACGTGNB
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in the species Homo sapiens
but has not reported in human yet. E2F3 has been shown to interact with TFE3, IGF2. and RYBP. E2F GRCh38: Ensembl release 89: ENSG00000112242 – Ensembl
E2F3
Protein-coding gene in the species Homo sapiens
"TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation". Mol. Cell. Biol. 13 (8): 4505–12
TFEC
Mammalian protein found in Homo sapiens
require additional transcription factors such as members of the AP-1 family, TFE3 and FoxG1 to regulate gene expression. Many TGFβ ligands use this pathway
SMAD4
Project to catalogue genetic mutations responsible for cancer
of type 2 tumors were heterogeneous, with alterations to CDKN2A, SETD2, TFE3, or increased expression of the NRF2–ARE pathway; loss of expression of CDKN2A
The_Cancer_Genome_Atlas
Medical condition
typically stain with CK7 with 'cuplike' staining for CAIX, and do not stain with TFE3 and AMACR. Renal cancer Renal cell carcinoma Rohan, SM.; Xiao, Y.; Liang
Clear cell papillary renal cell carcinoma
Clear_cell_papillary_renal_cell_carcinoma
Protein-coding gene in the species Homo sapiens
(October 1997). "Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma". Oncogene. 15 (18): 2233–9. doi:10
Non-POU domain-containing octamer-binding protein
Non-POU_domain-containing_octamer-binding_protein
Q14186 16597 TFDP2 HGNC:11751; Q14188 16598 TFDP3 HGNC:24603; Q5H9I0 16599 TFE3 HGNC:11752; P19532 16600 TFEB HGNC:11753; P19484 16601 TFEC HGNC:11754; O14948
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Medical condition
parcellaire CK20 - CK19 - AMACR (Racemase) - S100 + c-kit (CD117) + Cadherin-E + TFE3 - CAM5.2 + Renal oncocytoma is considered benign, cured by nephrectomy (partial
Renal_oncocytoma
Protein-coding gene in the species Homo sapiens
Verastegui C, Bertolotto C, Bille K, Abbe P, Ortonne JP, Ballotti R (Mar 2000). "TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional
TFEB
Protein-coding gene in the species Homo sapiens
complexes. When Ets1 interacts with other transcription factors (Runx1, Pax5, TFE3, and USF1) its final effect on transcription depends on whether C-terminal
ETS1
Protein-coding gene in the species Homo sapiens
Hallstrom TC, Tunyaplin C, et al. (2003). "Identification of E-Box Factor TFE3 as a Functional Partner for the E2F3 Transcription Factor". Mol. Cell. Biol
PKIB
Non-coding RNA in the species Homo sapiens
(Oct 1997). "Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma". Oncogene. 15 (18): 2233–9. CiteSeerX 10
SFPQ
papillary, 1; 605074; PRCC Renal cell carcinoma, papillary, 1; 605074; TFE3 Renal cell carcinoma, papillary, familial and sporadic; 605074; MET Renal
List_of_OMIM_disorder_codes
Medical condition
in chromatin remodeling (SETD2, BAP1, or PBRM) may lead to higher rate of TFE3/TFEB fusion. Additionally, CIMP papillary renal cell carcinoma tumors exhibited
Papillary renal cell carcinoma
Papillary_renal_cell_carcinoma
TFE3
TFE3
TFE3
TFE3
Male
Welsh
Welsh form of Latin Stephanus, STEFFAN means "crown."
Surname or Lastname
English
English : see Beaver 1.Italian : habitational name from any of numerous places called Belvedere, from bello ‘beautiful’ + vedere ‘to see’, ‘to look at’, for example Belvedere Marittimo in Cosenza and Belvedere di Spinello in Catanzaro. In some instances the surname may have arisen from a nickname with the same meaning.
Boy/Male
Indian, Punjabi, Sikh
Guru's Meditation
Girl/Female
English American Latin Hebrew
Feminine of Michael, meaning gift from God.
Girl/Female
Arabic, Muslim
The Mother of Kulsum
Surname or Lastname
English
English : patronymic form of Cousin.
Girl/Female
Hebrew
From the water.
Boy/Male
Hindu, Indian, Marathi
Fame
Boy/Male
Tamil
Chiranjib | சீராநà¯à®œà¯€à®ª
Man with long-life
Surname or Lastname
English and German
English and German : variant spelling of Hain.
TFE3
TFE3
TFE3
TFE3
TFE3