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Chemical compound
(RS)-MCPG is a phenylglycine derivative and a non-selective antagonist of group I and II metabotropic glutamate receptors (mGluRs). It has been used in
(RS)-MCPG
Chemical compound
which can be reductively cleaved with chromous reagents. N-Phenylglycine (RS)-MCPG Watkins, Jeff; Collingridge, Graham (1994). "Phenylglycine derivatives
Phenylglycine
Mammalian protein found in humans
Monellin Glutamate Lithium LY-344,545 Mavoglurant Remeglurant SIB-1893 (RS)-MCPG ADX-47273 CPPHA VU-29: Ki = 244 nM, EC50 = 9.0 nM; VU-36: Ki = 95 nM, EC50
Metabotropic glutamate receptor 5
Metabotropic_glutamate_receptor_5
Type of glutamate receptor
The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members
Metabotropic glutamate receptor
Metabotropic_glutamate_receptor
Chemical compound
metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5. DHPG was the first agonist shown to be selective for group I mGluRs. Agonist activity is found in
Dihydroxyphenylglycine
Neurological and psychiatric drug
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Deudextromethorphan/quinidine
Blue dye also used as a medication
of Health and Mental Hygiene. Retrieved 4 November 2023. Taylor GM, Avera RS, Strachan CC, Briggs CM, Medler JP, Pafford CM, et al. (February 2021). "Severe
Methylene_blue
Chemical compound
for other neuronal functions that are not typically controlled by iGluRs. mGluRs are split into 3 separate groups (Group I, Group II, Group III) based
AMN082
Derivative of aspartic acid found in the brain
Science & Business Media. ISBN 978-0-387-30172-3. Jung RE, Gasparovic C, Chavez RS, Flores RA, Smith SM, Caprihan A, Yeo RA (April 2009). "Biochemical support
N-Acetylaspartic_acid
Chemical compound
PMID 24909673. S2CID 19982406. Lepack AE, Bang E, Lee B, Dwyer JM, Duman RS (December 2016). "Fast-acting antidepressants rapidly stimulate ERK signaling
LY-341495
Chemical compound
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
L-687,384
Study of DNA modifications that do not change its sequence
along its 5' → 3' direction and where the cytosine is methylated (5-mCpG)). A 5-mCpG site has the lowest ionization potential for guanine oxidation.[citation
Epigenetics
Chemical compound
pomaglumetad has been shown to act as a potent full agonist at group II mGluRs as demonstrated by its ability to inhibit cyclic adenosine monophosphate,
Pomaglumetad
Chemical compound
glutamate receptor subtype mGluR5. O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn
DMeOB
Pharmaceutical drug
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Dextromethorphan/quinidine
Chemical compound
epilepsy and stroke. Metabotropic glutamate receptors, also known as mGluRs are a type of glutamate receptor which are members of the G-protein coupled
Quisqualic_acid
Chemical compound
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Metapramine
Neuron membrane protein
receptors (iGluRs) form the ion channel pore that activates when glutamate binds to the receptor. Metabotropic glutamate receptors (mGluRs) affect the cell
Glutamate_receptor
Chemical compound
Vezina P, Kim JH (August 2008). "Blockade of group II, but not group I, mGluRs in the rat nucleus accumbens inhibits the expression of conditioned hyperactivity
EGLU
Chemical compound
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Hypericin
Antibiotic medication
2165/11319280-000000000-00000. PMID 20642295. S2CID 24501240. Sweet RL, Gibbs RS (2001). Infectious Diseases of the Female Genital Tract (4th ed.). Lippincott
Minocycline
Investigational analgesic drug
(14 October 2010). "Overview: Novel Targets for New Analgesics". In Sinatra RS, Jahr JS, Watkins-Pitchford JM (eds.). The Essence of Analgesia and Analgesics
Ralfinamide
Combination drug
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Testosterone propionate/testosterone cypionate/prasterone
Testosterone_propionate/testosterone_cypionate/prasterone
Naturally occurring glutamate receptor agonist neurotoxin
mGluR3) metabotropic glutamate receptors. It is inactive at group III mGluRs. Ibotenic acid also acts as a weak agonist of the AMPA and kainate receptors
Ibotenic_acid
Medical usage of the prasterone compound
PMC 9113789. PMID 35254428. Benini V, Ruffolo AF, Casiraghi A, Degliuomini RS, Frigerio M, Braga A, et al. (2022). "New Innovations for the Treatment of
Prasterone
Chemical compound
channels, including nicotinic acetylcholine receptors (nAChRs) and ionotropic glutamate receptors (iGluRs). Synthetic analogues, including PhTX-343 and PhTX-12
Philanthotoxin
Medication
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Prasterone_sulfate
Protein found in humans
an increase in extrasynaptic glutamate, causing stimulation of Group 2 mGluRs and an inhibition of synaptic release of glutamate. Cysteine prodrugs also
Cystine/glutamate_transporter
Combination drug
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Estradiol valerate/prasterone enanthate
Estradiol_valerate/prasterone_enanthate
ClinicalTrials.gov. Retrieved 2025-10-05. "Pharmacokinetics and Safety of YA-101 (RS-D7) in Healthy Subjects". MDS Abstracts. Retrieved 2025-10-05. Da Luo Z, Liu
NMDA_receptor_modulator
Mammalian protein found in humans
not been determined. A possible connection has been suggested between mGluRs and neuromodulators, as mGluR1 antagonists block adrenergic receptor activation
Metabotropic glutamate receptor 1
Metabotropic_glutamate_receptor_1
Spice made from crocus flowers
Bibcode:2008PlMed..74.1316S, doi:10.1055/s-2008-1081293, PMC 3947403, PMID 18622904 Verma RS, Middha D (2010), "Analysis of Saffron (Crocus sativus L. Stigma) Components
Saffron
Chemical compound
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Agmatine
Cellular mechanism
along its 5' → 3' direction and where the cytosine is methylated (5-mCpG)). A 5-mCpG site has the lowest ionization potential for guanine oxidation. Oxidized
DNA_repair
Chemical compound
Sung KW, Choi S, Lovinger DM (November 2001). "Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses".
LY-307,452
Peptide neurotransmitter
N.C. (2009). "Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR". Neuropharmacology. 56 (6–7): 1060–67. doi:10.1016/j.neuropharm
N-Acetylaspartylglutamic_acid
Protein-coding gene in the species Homo sapiens
PMID 11784859. Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and
SAP30
Early anesthetic
one hundredth anniversary A paper that shows Clover's inhaler Atkinson, R.S. (1977). "Clover's portable regulating ether inhaler (1877)". Anaesthesia
ACE_mixture
Protein-coding gene in the species Homo sapiens
PMID 12354758. Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and
HDAC1
Chemical compound
Theanine Antagonists: BAY 36-7620 CPCCOEt Cyclothiazide LY-367,385 LY-456,236 MCPG NPS-2390 mGluR5Tooltip Metabotropic glutamate receptor 5 Agonists: ACPD ADX-47273
Prasterone_enanthate
Mammalian protein found in humans
doi:10.1016/j.ejphar.2008.06.089. PMID 18634781. Dwyer JM, Lepack AE, Duman RS (May 2012). "mTOR activation is required for the antidepressant effects of
Metabotropic glutamate receptor 2
Metabotropic_glutamate_receptor_2
RS MCPG
RS MCPG
Surname or Lastname
English
English : habitational name from a place in Norfolk, so named from Old English græs, gærs ‘grass(land)’, ‘pasturage’ + hÄm ‘homestead’ or hamm ‘enclosure hemmed in by water’.
Surname or Lastname
English
English : habitational name from Kersey in Suffolk, recorded in Domesday Book as Careseia, probably from Old English cærs ‘watercress’ + ēg ‘island’, ‘area of dry land in a marsh’.
Male
Welsh
Welsh form of Greek Georgios, SIÔRS means "earth-worker, farmer."
Surname or Lastname
North German and Frisian (Jürs)
North German and Frisian (Jürs) : patronymic form from a northern form of the personal name Georg (see George). Compare Jurgens.English : variant of Jowers.
RS MCPG
RS MCPG
Girl/Female
Muslim
Mehrunissa | Ù…ÛŒÛرونیسسا
Benevolent
Girl/Female
American, Australian, British, Dutch, English, German, Hebrew
Sea of Bitterness; Bitter; Wished-for Child
Boy/Male
Hindu
Clear
Boy/Male
German Teutonic
Noble friend.
Female
Irish
Irish name FUAMNACH means "jealous." In mythology, this is the name of the first wife of Midir, lord of the underworld. She is a witch goddess who turns Midir's second wife, the heroine ÉtaÃn, into a pool of water, then a worm, and finally a beautiful butterfly.Â
Boy/Male
Tamil
Fresh butter, Gentle, Soft, Always new
Boy/Male
American, Anglo, British, English, German, Teutonic
Protector of the Land; Wealthy Defender
Boy/Male
Hindu, Indian, Marathi
The Moon
Male
Welsh
 Variant spelling of Welsh Wyn, WYNN means "blessed, fair, holy, white." Compare with another form of Wynn.
Boy/Male
English
Noble or famous.
RS MCPG
RS MCPG
RS MCPG
RS MCPG
RS MCPG