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RHOBTB2

RHOBTB2

Protein-coding gene in the species Homo sapiens

domain-containing protein 2 is a protein that in humans is encoded by the RHOBTB2 gene. RHOBTB2 is a member of the evolutionarily-conserved RhoBTB subfamily of

RHOBTB2

RhoBTB

Protein subgroup of the Rho family of small GTPases

in humans. They found three and called them RhoBTB1, RhoBTB2, and RhoBTB3. RhoBTB1 and RhoBTB2 are much more homologous than RhoBTB3. Further analysis

RhoBTB

Rho family of GTPases

Family of small signalling G proteins

Rac lamellipodia Rac1 Rac2 Rac3 RhoG RhoBTB protein stability RhoBTB1 RhoBTB2 RhoBTB3 RhoH Rac agonist? RhoH Rho (subclass) ↑stress fibres and ↑focal

Rho family of GTPases

Rho_family_of_GTPases

CUL3

Protein-coding gene in humans

Another substrate of CRL complex is a candidate tumour suppressor protein RhoBTB2. CUL3 has been shown to interact with: CAND1, Cyclin E1, DCUN1D1, KEAP1

CUL3

Ras superfamily

Protein superfamily of small GTPases

RRAS; RRAS2 Rho cytoskeletal dynamics/morphology RHOA; RHOB; RHOBTB1; RHOBTB2; RHOBTB3; RHOC; RHOD; RHOF; RHOG; RHOH; RHOJ; RHOQ; RHOU; RHOV; RND1; RND2;

Ras superfamily

Ras_superfamily

List of human protein-coding genes 7

P61586 13736 RHOB HGNC:668; P62745 13737 RHOBTB1 HGNC:18738; O94844 13738 RHOBTB2 HGNC:18756; Q9BYZ6 13739 RHOBTB3 HGNC:18757; O94955 13740 RHOC HGNC:669;

List of human protein-coding genes 7

List_of_human_protein-coding_genes_7