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Cancer originating in precursors to muscle cells
are embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma, pleomorphic rhabdomyosarcoma, and spindle-cell/sclerosing rhabdomyosarcoma. Embryonal and
Rhabdomyosarcoma
Most common soft-tissue cancer in children
Embryonal rhabdomyosarcoma (ERMS) is a rare histological form of cancer in the connective tissue wherein the mesenchymally-derived cells (rhabdomyoblasts)
Embryonal_rhabdomyosarcoma
Type of skeletal muscle tumor
Alveolar rhabdomyosarcoma (ARMS) is a subtype of the rhabdomyosarcoma family of soft-tissue cancers whose lineage derives mesenchymal stem cells, the progenitors
Alveolar_rhabdomyosarcoma
Cancer originating in connective tissue
Liposarcoma Leiomyosarcoma Malignant peripheral nerve sheath tumor Rhabdomyosarcoma Synovial sarcoma Malignant solitary fibrous tumor. Liposarcoma (includes
Sarcoma
Largest known protein in human muscles
Titin (/ˈtaɪtɪn/; also called connectin) is a protein that in humans is encoded by the TTN gene. The protein, which is over 1 μm in length, functions as
Titin
Medical condition
Spindle cell rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma first described by Cavazzana, Schmidt and Ninfo in 1992. This subtype has a more
Spindle_cell_rhabdomyosarcoma
Malignant pediatric orbital tumor
Orbital rhabdomyosarcoma is a subtype of rhabdomyosarcoma (RMS), a malignant soft-tissue tumor arising from primitive mesenchymal cells with skeletal
Orbital_rhabdomyosarcoma
Childhood soft-tissue cancer in mucosa-lined organs
Sarcoma botryoides or botryoid sarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow, mucosa lined structures
Sarcoma_botryoides
Variability in the size and shape of a cell or nucleus
Arias-Stella reaction. A rare type of rhabdomyosarcoma that is found in adults is known as pleomorphic rhabdomyosarcoma. Despite the prevalence of pleomorphism
Pleomorphism_(cytology)
Medical condition
Sclerosing rhabdomyosarcoma is a rare subtype of rhabdomyosarcoma that was characterized by Folpe et al. in 2002.[citation needed] It is microscopically
Sclerosing_rhabdomyosarcoma
Human disease
muscle Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma Sarcoma botryoides Orbital rhabdomyosarcoma Alveolar rhabdomyosarcoma Leiomyoma Cutaneous
Skin_sarcoma
Clinical trial cooperative group
The Intergroup Rhabdomyosarcoma Study Group (IRS) was a U.S. and Canadian clinical trial cooperative group created with the mission of studying childhood
Intergroup Rhabdomyosarcoma Study Group
Intergroup_Rhabdomyosarcoma_Study_Group
Malignant tumors of soft tissues excluding skeletal muscle tissue
Non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) are malignant tumors that develop in soft tissue (muscle, tendon, fat, etc.) but which do not possess
Non-rhabdomyosarcoma soft tissue sarcomas
Non-rhabdomyosarcoma_soft_tissue_sarcomas
Dutch social media influencer and cancer activist (2007–2026)
gained national recognition for her openness about her battle with rhabdomyosarcoma, a rare form of cancer, and her commitment to supporting others facing
Jade_Kops
Medical condition
during their sleep. Leiomyosarcoma is sarcoma of smooth muscle, and rhabdomyosarcoma is sarcoma of striated muscle. However, the term myosarcoma itself
Myosarcoma
Laboratory assessment of re-epithelialization in cell cultures
Scratch wound healing assay experiment of rhabdomyosarcoma, a cancer cell line.
Wound_healing_assay
Type of insect gene
significance, being linked to diseases such as Waardenburg Syndrome and rhabdomyosarcoma. The gooseberry gene was first described in a 1980 research paper on
Gooseberry_(gene)
Cell type found in certain tumors (rhabdomyosarcomas)
A rhabdomyoblast is a cell type which is found in some rhabdomyosarcomas. When found histologically, a rhabdomyoblast aids the diagnosis of embryonal
Rhabdomyoblast
Autosomal dominant cancer syndrome
reviewing the medical records and death certificates of childhood rhabdomyosarcoma patients. The disease is also known as SBLA, for the Sarcoma, Breast
Li–Fraumeni_syndrome
Topics referred to by the same term
Project ARMS, a 1997 Japanese manga series also known as ARMS Alveolar rhabdomyosarcoma, a form of cancer Arms, Amps root mean square, seen in electrical specifications
Arms
Species of bacterium
Pantoea agglomerans ZMR7 was reported to decrease the viability of rhabdomyosarcoma (RD) and breast cancer (MDA) cells compared with untreated cancer cells
Pantoea_agglomerans
Chemical compound
used to treat a number of types of cancer. This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain
Dactinomycin
Malignant tumor that develops in soft tissue
children and adolescents under age 20, certain histologies are common (rhabdomyosarcoma, synovial sarcoma). Around 3,300 people were diagnosed with soft-tissue
Soft-tissue_sarcoma
widely as some of the other small cell tumors of childhood such as rhabdomyosarcoma or neuroblastoma. Askin FB, Rosai J, Sibley RK, Dehner LP, McAlister
Askin's_tumor
Protein found in humans
human Rhabdomyosarcoma tumors and 4 of 4 human cell lines derived from rhabdomyosarcoma. The tumor cases included 6 cases of Alveolar rhabdomyosarcoma, 2
Fibroblast growth factor receptor 1
Fibroblast_growth_factor_receptor_1
Genetic disorder
FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) Other Fragile X syndrome Uniparental
Down_syndrome
Rhabdomyosarcoma 2 associated transcript (RMST) is a long non-coding RNA. In humans, it is located on chromosome 12q21. It is expressed at higher levels
RMST_(gene)
Malignant neoplastic disease of the esophagus
carcinoma, and non-epithelial tumors, such as leiomyosarcoma, melanoma, rhabdomyosarcoma and lymphoma, among others. Staging is based on the TNM staging system
Esophageal_cancer
Medical condition
cells give it a microscopic resemblance to malignant cells found in rhabdomyosarcoma (RMS), a rare neoplasm arising from transformed skeletal muscle. Despite
Large-cell lung carcinoma with rhabdoid phenotype
Large-cell_lung_carcinoma_with_rhabdoid_phenotype
American singer-songwriter (born 1948)
she had met through the Make-a-Wish Foundation in Los Angeles with rhabdomyosarcoma, a rare cancer. On January 13, 2011, Reprise announced Nicks's upcoming
Stevie_Nicks
American motorcycle road racing rider
that. In 2013 he was diagnosed with anaplastic rhabdomyosarcoma (also known as pleomorphic rhabdomyosarcoma), a rare form of cancer. He died on 7 May 2016
Michael_Czysz
American pediatric surgeon
"Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the
Andrea_Hayes-Jordan
Chemical compound
in treatment of acute myeloid leukemia, myelodysplastic syndrome, rhabdomyosarcoma, and medulloblastoma. Al Idrus A (30 April 2019). "Lilly dumps phase
Prexasertib
American comedian and television actor (1984–2026)
Duong's death in 2026. In 2025, Duong was diagnosed with alveolar rhabdomyosarcoma. He died of septic shock at the Saint John's Health Center in Santa
Alex_Duong
Condition present at birth regardless of cause
FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) Other Fragile X syndrome Uniparental
Birth_defect
cardiopathy genital anomalies Rhabdomyosarcoma Rhabdomyosarcoma 1 Rhabdomyosarcoma 2 Rhabdomyosarcoma, alveolar Rhabdomyosarcoma, embryonal Rheumatic fever
List_of_diseases_(R)
Swelling of the conjunctiva
Urticaria Trauma, including surgical trauma Keratitis Mucor infection Rhabdomyosarcoma of the orbit An eye doctor may most often diagnose chemosis by doing
Chemosis
Short story and 1995 television film directed by Peter Werner
aspiring knight, also named Millard, to conquer Raptenahad (a play on "rhabdomyosarcoma", the cancer Chris had), a magic-wielding evil queen who symbolized
The_Four_Diamonds
Genus of bacteria
Pantoea agglomerans ZMR7 was reported to decrease the viability of rhabdomyosarcoma (RD) and breast cancer (MDA) cells compared with untreated cancer cells
Pantoea
X chromosome monosomy
FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) Other Fragile X syndrome Uniparental
Turner_syndrome
American college football season
West, fifth). Diagnosed with a rare and aggressive muscle cancer (rhabdomyosarcoma) shortly after the 1994 season, Allen underwent surgery in August 1996
1996 Boise State Broncos football team
1996_Boise_State_Broncos_football_team
Girl who died of cancer (2002–2013)
overnight without warning. Bella was diagnosed with stage four alveolar rhabdomyosarcoma in July 2007 with widespread metastases. She experienced six cancer
Bella_Rodriguez-Torres
Family of transport proteins
carrier family 22 member 18 Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer SLC22A19
Organic cation transport protein
Organic_cation_transport_protein
Protein
Forkhead box protein O1 (FOXO1), also known as forkhead in rhabdomyosarcoma (FKHR), is a protein that in humans is encoded by the FOXO1 gene. FOXO1 is
Forkhead_box_protein_O1
Medical condition
FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) Other Fragile X syndrome Uniparental
Fryns–Aftimos_syndrome
American oncologist (died 2024)
and writing. She wrote and spoke publicly about surviving childhood rhabdomyosarcoma in the New England Journal of Medicine. While training at Harvard Medical
Shekinah_Elmore
Protein-coding gene in the species Homo sapiens
may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies
PHLDA2
Chemical element with atomic number 74 (W)
weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats". Environmental Health Perspectives. 113 (6): 729–734
Tungsten
Purplish skin bumps on a newborn due to overproduction of blood
erythropoietin administration. Some types of cancers can cause it such as rhabdomyosarcoma, extrosseal Ewing sarcoma, Langerhans cell histiocytosis, congenital
Blueberry_muffin_baby
Medical condition
evaluation. Rhabdomyosarcoma is a rare malignant tumor in neonates that can occasionally involve the oral cavity. Unlike congenital epulis, rhabdomyosarcoma typically
Congenital_epulis
Disease of the lymph nodes
there are multiple enlarged nodes which feel rubbery to palpation. Rhabdomyosarcoma Neuroblastoma Surgical trauma, e.g. following a biopsy in the mouth
Cervical_lymphadenopathy
Female reproductive organ that produces egg cells
Müllerian tumor Vagina Squamous-cell carcinoma of the vagina Botryoid rhabdomyosarcoma Clear-cell adenocarcinoma of the vagina Vaginal intraepithelial neoplasia
Ovary
microscopic (General analysis of urine) RML right middle lobe (of lung) RMS rhabdomyosarcoma RMSF rocky mountain spotted fever RNA ribonucleic acid RNP ribonucleoprotein
List of medical abbreviations: R
List_of_medical_abbreviations:_R
Aggressive and rare cancer
young patients can be mistaken for other abdominal tumors including rhabdomyosarcoma, neuroblastoma, and mesenteric carcinoid. In older patients DSRCT can
Desmoplastic small-round-cell tumor
Desmoplastic_small-round-cell_tumor
Paired box gene 3
homeodomain, these mutations often affect DNA binding function. Alveolar rhabdomyosarcoma (ARMS) is an aggressive soft tissue sarcoma that occurs in children
PAX3
American businessman
helped provide bridge funding for Duke Children's research on alveolar rhabdomyosarcoma (RMS), which was later awarded a National Cancer Institute Moonshot
Glenn_H._Schiffman
Assisted reproductive technology procedure
risks of certain others including retinoblastoma, hepatoblastoma and rhabdomyosarcoma. In some cases, laboratory mix-ups (misidentified gametes, transfer
In_vitro_fertilisation
Bunches of grapes sign (hepatic abscess) Bunch of grapes sign (botryoid rhabdomyosarcoma) Bunch of grapes sign (bronchiectasis) Bunch of grapes sign (hydatidiform
List_of_radiologic_signs
Group of malignant tumors in cats and dogs
tissue sarcomas includes fibrosarcoma, hemangiopericytoma, liposarcoma, rhabdomyosarcoma, leiomyosarcoma, malignant fibrous histiocytoma, malignant nerve sheath
Soft tissue sarcoma in cats and dogs
Soft_tissue_sarcoma_in_cats_and_dogs
American mixed martial artist (born 1983)
disclosed that his 14‑year‑old son had battled and recovered from rhabdomyosarcoma, a rare pediatric cancer, following extensive treatment over the previous
Jim_Miller_(fighter)
American football player and coach (1943–1996)
Division I-AA title game in 1994. In 1994, Allen was diagnosed with rhabdomyosarcoma, a rare form of muscle cancer. He continued coaching until shortly
Pokey_Allen
Chemical compound
as a treatment agent in basal cell carcinoma, medulloblastoma and rhabdomyosarcoma (tumours commonly resulting from excessive Shh activity), glioblastoma
Cyclopamine
Medical condition
focusing on using chemotherapy protocols that are effective against rhabdomyosarcoma in combination with surgery and radiation therapy. Recent studies using
Atypical teratoid rhabdoid tumor
Atypical_teratoid_rhabdoid_tumor
2nd episode of the 2nd season of House
seeing. She is a nine-year-old girl with terminal cancer (alveolar rhabdomyosarcoma), but tests reveal that her cancer is in remission, meaning that the
Autopsy_(House)
American surgeon (1925–2021)
factors of the UICC staging system in childhood rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Study (IRS-II)". Journal of Clinical Oncology
Walter_Lawrence_Jr.
(2012), world champion (2014). Aoi Fujino, 27, Japanese gravure idol, rhabdomyosarcoma. Paolo Gillet, 96, Italian Roman Catholic prelate, auxiliary bishop
Deaths_in_January_2026
the urinary bladder is squamous cell carcinoma, adenocarcinoma, or rhabdomyosarcoma. The most frequent symptoms of transitional cell carcinoma are blood
Bladder cancer in cats and dogs
Bladder_cancer_in_cats_and_dogs
Medical condition
as the vagina. Malignant skeletal muscle tumors are referred to as rhabdomyosarcoma. Only rare cases of possible malignant change have been reported in
Rhabdomyoma
Insertion of molecules between DNA
lymphoma), and dactinomycin (used in Wilm's tumour, Ewing's Sarcoma, rhabdomyosarcoma). Metallointercalators are complexes of a metal cation with polycyclic
Intercalation_(biochemistry)
Japanese gravure idol (1998–2026)
feeling unwell for a few months, Fujino was diagnosed with a malignant rhabdomyosarcoma. She announced her cancer diagnosis in April 2023 and left the hospital
Aoi_Fujino
Neoplasm of the vulva
Mixed tumors of the vulva Tumors of skin appendage origin Embryonal rhabdomyosarcoma (sarcoma botryoides) Leiomyosarcoma Fibrous histiocytoma Proximal epithelioid
Vulvar_tumors
Type of cancer
of small-blue-round-cell tumors, which includes lymphoma, alveolar rhabdomyosarcoma, and desmoplastic small round cell tumor, among others. On conventional
Ewing_sarcoma
Natural premature termination of pregnancy
FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) Other Fragile X syndrome Uniparental
Miscarriage
Medical ultrasound examination of the scrotum
occur; the most common malignant tumors in infants and children are rhabdomyosarcomas. Other malignant tumors include liposarcoma, leiomyosarcoma, malignant
Scrotal_ultrasound
Medical condition
tumors such as pleuropulmonary blastoma, Wilms tumor and cervical rhabdomyosarcoma. Closely related terms include arrhenoblastoma and androblastoma. Both
Sertoli–Leydig_cell_tumour
Cancerous tumors composed of small cells which stain blue
small-round-cell tumour Ewing sarcoma/PNET Neuroblastoma Medulloblastoma Rhabdomyosarcoma Synovial sarcoma Carcinoid tumor Mesothelioma Small cell lung cancer
Small-blue-round-cell_tumor
fibrous histiocytoma of bone/osteosarcoma Myxosarcoma Osteosarcoma Rhabdomyosarcoma Astrocytoma Anaplastic astrocytoma Brainstem glioma Choroid plexus
List_of_cancer_types
abbreviated as AROM) ARMD age-related macular degeneration ARMS alveolar rhabdomyosarcoma AROM active range of motion artificial rupture of membranes ART antiretroviral
List of medical abbreviations: A
List_of_medical_abbreviations:_A
Medical intervention
in children between the ages of 2 & 10 years old as an aggressive rhabdomyosarcoma, although there have been diagnoses of children as young as 3 months
Ureterosigmoidostomy
Mammalian protein found in humans
inhibitor targets MDM2 and induces apoptosis in embryonal and alveolar rhabdomyosarcoma cells with wild-type p53". British Journal of Cancer. 101 (5): 774–81
P53
Medical condition
Müllerian tumor Vagina Squamous-cell carcinoma of the vagina Botryoid rhabdomyosarcoma Clear-cell adenocarcinoma of the vagina Vaginal intraepithelial neoplasia
Vaginal_melanoma
Medical condition
sarcoma of liver, infantile choriocarcinoma of liver, and biliary rhabdomyosarcoma. Increased risk for liver cancer in children can be caused by Beckwith–Wiedemann
Liver_cancer
Explosive weapon
Services study, from 2005, found that HMTA shrapnel rapidly induces rhabdomyosarcoma in laboratory rats. Tungsten alloy carcinogenicity may be most closely
Dense_inert_metal_explosive
Type of malignant tumor found in animals
eleven years. Fibrosarcoma is the most common VAS; other types include rhabdomyosarcoma, myxosarcoma, chondrosarcoma, malignant fibrous histiocytoma, and undifferentiated
Injection-site_sarcoma
Cancer syndrome
Lauten M, Pollett A, Niemeyer CM, Gallinger S, Wimmer K (June 2009). "Rhabdomyosarcoma in patients with constitutional mismatch-repair-deficiency syndrome"
Mismatch repair cancer syndrome
Mismatch_repair_cancer_syndrome
Medical condition
entity in 1978. The term rhabdoid was used due to its similarity with rhabdomyosarcoma under the light microscope. The exact pathogenesis of MRT is unknown
Malignant_rhabdoid_tumour
Genetic overgrowth disorder
Embryonal tumor (e.g., Wilms tumor, hepatoblastoma, neuroblastoma, rhabdomyosarcoma) in childhood Visceromegaly involving one or more intra-abdominal organs
Beckwith–Wiedemann_syndrome
Mammalian protein found in Mus musculus
been shown to drive mitogenesis, dedifferentiation, and metastasis in rhabdomyosarcoma. IL-4 has a significant effect on tumor progression. Increased IL-4
Interleukin_4
Cancer research center in Virginia, U.S.
found that the same gene factors in two forms of the childhood cancer rhabdomyosarcoma. Identification of a gene contributing to small-cell lung cancer, that
UVA Comprehensive Cancer Center
UVA_Comprehensive_Cancer_Center
Pharmaceutical drug
for aggressive fibromatosis (desmoid tumor). It is also active in rhabdomyosarcoma. Vinorelbine has a number of side effects that can limit its use:
Vinorelbine
Diagnosis classification
Rhabdomyoma, NOS M8900/3 Rhabdomyosarcoma, NOS Rhabdosarcoma M8901/3 Pleomorphic rhabdomyosarcoma, adult type Pleomorphic rhabdomyosarcoma, NOS M8902/3 Mixed
International Classification of Diseases for Oncology
International_Classification_of_Diseases_for_Oncology
Protein-coding gene in the species Homo sapiens
been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. ENSG00000273562
NAP1L4
Genus of viruses
"Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro". The Journal of Infectious Diseases. 186 (8): 1161–1164
Enterovirus
retrograde cholangiopancreatography ERM epiretinal membrane ERMS embryonal rhabdomyosarcoma ERT enzyme replacement therapy ESA erythropoiesis-stimulating agent
List of medical abbreviations: E
List_of_medical_abbreviations:_E
British cell biologist
cell lines at the Institute for Cancer Research in London. DNA from a rhabdomyosarcoma cell line and a fibrosarcoma cell line transformed an NIH/3T3 mouse
Alan_Hall
Medical condition
associated with Costello syndrome is a soft tissue tumor called a rhabdomyosarcoma. Other cancers also have been reported in children and adolescents
Costello_syndrome
Small molecules that inhibit the Hedgehog signaling pathway
affinity of GLI1 and GLI2 in multiple cancer cell lines, including rhabdomyosarcoma, osteosarcoma, neuroblastoma, and ovarian cancer. Arsenic Trioxide
Hedgehog_pathway_inhibitor
English bassist (1964–2022)
Smith. He had four children. Ryder's son Chico was diagnosed with rhabdomyosarcoma, a rare soft-tissue cancer, in 2012 at the age of nine. Doctors judged
Paul_Ryder
Anatomy of the equine tongue
rare cases of vascular hamartoma, typically benign growths. A case of rhabdomyosarcoma, on the tongue of a five-year-old Quarter Horse mare, was studied in
Horse_tongue
American football player (born 1986)
which he met Aiden Binkley, a terminally ill 11-year-old struck with rhabdomyosarcoma. Sanchez developed a bond with Binkley and the two remained close friends
Mark_Sanchez
RHABDOMYOSARCOMA
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