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RGS4

  • RGS4
  • Protein-coding gene in the species Homo sapiens

    signaling 4 also known as RGP4 is a protein that in humans is encoded by the RGS4 gene. RGP4 regulates G protein signaling. Regulator of G protein signalling

    RGS4

    RGS4

    RGS4

  • Chemistry
  • Scientific study of matter's behavior and properties

    and characterise chemical compounds. Biochemistry: a ribbon diagram of the RGS4 protein, based on the crystal structure PDB entry 1AGR, illustrating secondary‑structure

    Chemistry

    Chemistry

    Chemistry

  • Regulator of G protein signaling
  • Protein family

    which is required for activity. Some small RGS proteins such as RGS1 and RGS4 are little more than an RGS domain, while others also contain additional

    Regulator of G protein signaling

    Regulator of G protein signaling

    Regulator_of_G_protein_signaling

  • CCG-4986
  • Chemical compound

    selective inhibitor of the regulator of G protein signalling protein subtype RGS4. Regulators of G protein signalling are proteins which act to limit and shorten

    CCG-4986

    CCG-4986

    CCG-4986

  • Mu-opioid receptor
  • Class of opioid receptors found in humans

    the β-arrestins arrestin beta 1 and arrestin beta 2, and the RGS proteins RGS4, RGS9-2, RGS14, and RGSZ2. Long-term or high-dose use of opioids may also

    Mu-opioid receptor

    Mu-opioid receptor

    Mu-opioid_receptor

  • RGS5
  • Protein-coding gene in the species Homo sapiens

    PMID 12477932. Morris DW, Rodgers A, McGhee KA, et al. (2005). "Confirming RGS4 as a susceptibility gene for schizophrenia". Am. J. Med. Genet. B Neuropsychiatr

    RGS5

    RGS5

    RGS5

  • Arginine finger
  • Catalytic amino acid residue

    catalysis of GTP can be assisted by aluminum tetrafluoride (AlF 4) and RGS4. Heterotrimeric G proteins are larger three-part proteins serve in signal

    Arginine finger

    Arginine_finger

  • RGS9
  • Protein-coding gene in the species Homo sapiens

    protein involved in terminating signalling by the mu opioid receptor (although RGS4 and RGS17 are also involved), and is thought to be important in the development

    RGS9

    RGS9

    RGS9

  • GTPase-activating protein
  • Family of regulatory proteins

    a downstream target of G protein signaling. PIP3 binds and inhibits the RGS4 GAP. Such inhibition of GAP may perhaps "prime" the signaling pathway for

    GTPase-activating protein

    GTPase-activating_protein

  • Epigenetics of cocaine addiction
  • Field of study

    post-synaptic influences. They knew that RGS4 proteins can modulate G-protein-coupled receptor function, and since RGS4 levels can increase or decrease in response

    Epigenetics of cocaine addiction

    Epigenetics_of_cocaine_addiction

  • RGS2
  • Protein-coding gene in the species Homo sapiens

    PMID 10791963. Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes

    RGS2

    RGS2

    RGS2

  • GNAQ
  • Protein-coding gene in the species Homo sapiens

    interact with: Beta adrenergic receptor kinase, Bruton's tyrosine kinase, RGS16 RGS4 RIC8A, and Sodium-hydrogen antiporter 3 regulator 1. List of genes mutated

    GNAQ

    GNAQ

    GNAQ

  • Alfred G. Gilman
  • American pharmacologist (1941–2015)

    S2CID 18993038. Berman, David M; Wilkie, Thomas M; Gilman, Alfred G (1996). "GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits"

    Alfred G. Gilman

    Alfred G. Gilman

    Alfred_G._Gilman

  • Risk factors of schizophrenia
  • Risk factors related to schizophrenia

    (DTNBP1) and neuregulin (NRG1), and that a number of other genes (such as COMT, RGS4, PPP3CC, ZDHHC8, DISC1, and AKT1) showed some early promising results. Knockout

    Risk factors of schizophrenia

    Risk factors of schizophrenia

    Risk_factors_of_schizophrenia

  • GNAI1
  • Protein-coding gene in humans

    Wilkie TM (Jul 1997). "The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro". Proceedings

    GNAI1

    GNAI1

    GNAI1

  • PIP4K2A
  • Kinase enzyme

    Verzijlbergen K, Caron S, Verduijn W, et al. (March 2007). "The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophrenia"

    PIP4K2A

    PIP4K2A

    PIP4K2A

  • RGS8
  • Protein-coding gene in the species Homo sapiens

    G-protein signalling 8". Berman DM, Wilkie TM, Gilman AG (1996). "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits"

    RGS8

    RGS8

    RGS8

  • RGS16
  • Protein-coding gene in the species Homo sapiens

    2677. PMID 10072511. Berman DM, Wilkie TM, Gilman AG (Aug 1996). "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits"

    RGS16

    RGS16

    RGS16

  • D. James Surmeier
  • American neuroscientist

    (muscarinic acetylcholine auto receptor) signaling along with an up-regulation of RGS4 (regulators of G protein signaling) expression in cholinergic neurons, culminating

    D. James Surmeier

    D._James_Surmeier

  • Proline oxidase
  • Protein-coding gene in the species Homo sapiens

    Li D, He L (Oct 2006). "Association study of the G-protein signaling 4 (RGS4) and proline dehydrogenase (PRODH) genes with schizophrenia: a meta-analysis"

    Proline oxidase

    Proline oxidase

    Proline_oxidase

  • List of human protein-coding genes 7
  • HGNC:9991; Q08116 13694 RGS2 HGNC:9998; P41220 13695 RGS3 HGNC:9999; P49796 13696 RGS4 HGNC:10000; P49798 13697 RGS5 HGNC:10001; O15539 13698 RGS6 HGNC:10002; P49758

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • RGS10
  • Protein-coding gene in the species Homo sapiens

    Wilkie TM (Jul 1997). "The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro". Proceedings

    RGS10

    RGS10

    RGS10

  • RGS19
  • Protein-coding gene in the species Homo sapiens

    G-protein signalling 19". Berman DM, Wilkie TM, Gilman AG (1996). "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits"

    RGS19

    RGS19

    RGS19

  • GNAI3
  • Protein-coding gene in humans

    v t e PDB gallery 1agr: COMPLEX OF ALF4-ACTIVATED GI-ALPHA-1 WITH RGS4 1as0: GTP-GAMMA-S BOUND G42V GIA1 1as2: GDP+PI BOUND G42V GIA1 1as3: GDP BOUND G42V

    GNAI3

    GNAI3

    GNAI3

  • COPB2
  • Protein-coding gene in humans

    [supplied by OMIM] COPB2 has been shown to interact with: COPB1, PRKCE, and RGS4. GRCh38: Ensembl release 89: ENSG00000184432 – Ensembl, May 2017 GRCm38:

    COPB2

    COPB2

    COPB2

  • COPG
  • Protein-coding gene in humans

    PMID 10931946. Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes

    COPG

    COPG

    COPG

  • RGS17
  • Protein-coding gene in the species Homo sapiens

    inactive G-protein heterotrimers, thereby terminating the signal. Along with RGS4, RGS9 and RGS14, RGS17 plays an important role in termination of signalling

    RGS17

    RGS17

    RGS17

  • COPB1
  • Protein-coding gene in humans

    PMID 10921873. Sullivan BM, Harrison-Lavoie KJ, Marshansky V, et al. (2000). "RGS4 and RGS2 Bind Coatomer and Inhibit COPI Association with Golgi Membranes

    COPB1

    COPB1

    COPB1

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Online names & meanings

  • Pendlebury
  • Surname or Lastname

    English (Manchester and Lancashire)

    Pendlebury

    English (Manchester and Lancashire) : habitational name from a place in Greater Manchester called Pendlebury, from the hill name Pendle (composed of the Celtic element penn ‘hill’, ‘head’ + a tautologous Old English hyll) + Old English burh ‘castle’, ‘fortified town’.

  • Sundari
  • Girl/Female

    Assamese, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Punjabi, Sanskrit, Sikh, Tamil, Telugu

    Sundari

    Beautiful

  • Lindsie
  • Girl/Female

    British, Christian, English

    Lindsie

    From the Island of the Lime Tree; Lincoln's Wetlands

  • BISERA
  • Female

    Bulgarian

    BISERA

    , beads, or, pearls.

  • Pearly
  • Girl/Female

    Hindu

    Pearly

    Pearl Pearly just similar to Pearl

  • KEKARA
  • Male

    Egyptian

    KEKARA

    , the royal scribe of the granaries.

  • Saptanshu | ஸப்தாந்ஷு
  • Boy/Male

    Tamil

    Saptanshu | ஸப்தாந்ஷு

    Fire

  • Shukrajyothi | ஷுக்ரஜ்யோதீ
  • Girl/Female

    Tamil

    Shukrajyothi | ஷுக்ரஜ்யோதீ

    Name of a Raga

  • Parimalan
  • Boy/Male

    Hindu, Indian, Tamil

    Parimalan

    Against Desire

  • Al-GafÛr
  • Boy/Male

    Indian

    Al-GafÛr

    The forgiving

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RGS4

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