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Chemical compound
Quinuclidine is an organic compound with the formula HC(C2H4)3N. It is a bicyclic amine that can be viewed as a tied back version of triethylamine. It
Quinuclidine
Chemical compound
to quinuclidine, but the latter has one of the nitrogen atoms replaced by a carbon atom. Regarding their structures, both DABCO and quinuclidine are
DABCO
Chemical compound
contrast quinuclidine is about 100x more basic. Its hydrochloride salt can be synthesized by a Dieckman condensation: It is a precursor to quinuclidine. Organic
3-Quinuclidone
Stimulant drug
2-Butyl-3-(p-tolyl)quinuclidine (BTQ) is a stimulant dopamine reuptake inhibitor (DRI). It is one of a number of substituted quinuclidine derivatives developed
Butyltolylquinuclidine
Chemical compound
Chemically, it is a quinuclidine derivative. The drug has antiarrhythmic properties, probably due to the presence of a quinuclidine nucleus in the molecule's
Quifenadine
Chemical agent and drug construction
product, a chiral molecule containing four stereocenters within the quinuclidine bicyclic amine group. With four stereocenters present in the structure
Quinine_total_synthesis
Military incapacitating agent
aqueous alkali. Structurally, BZ is an ester of benzilic acid joined to a quinuclidine unit and a hydroxy group. Symptoms begin between 30 minutes and several
3-Quinuclidinyl_benzilate
Chemical bond theory
bases to BF3 Lewis base Donor atom Enthalpy of complexation (kJ/mol) Quinuclidine N 150 Et3N N 135 Pyridine N 128 Acetonitrile N 60 DMA O 112 DMSO O 105
Lewis_acids_and_bases
Drug that binds to and activates nicotinic acetylcholine receptors
Many derivatives of quinuclidine - such as quinuclidine amide - are known to be α7 nAChR agonists. SAR studies for quinuclidine amide have identified
Nicotinic_agonist
Chemical compound
atropine the bicyclic ring is tropane, solifenacin replaces it with quinuclidine. The free base is a yellow oil, while the salt solifenacin succinate
Solifenacin
Medication used to treat malaria and babesiosis
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to Plasmodium falciparum that is resistant to
Quinine
Chemical compound class
benzylamino quinuclidine structure, which was called CP-96345 (figure 1). CP-96345 has a rather simple structure, composed of a rigid quinuclidine scaffold
NK1_receptor_antagonist
Chemical reaction
system the reaction rate is not only accelerated (150000 fold compared to quinuclidine) but the halide order is also changed The reaction is named after its
Menshutkin_reaction
Chemical reaction
asymmetric dihydroxylation, but replacing the chiral ligands with the achiral quinuclidine to give a racemic reaction product (assuming an achiral starting material
Upjohn_dihydroxylation
Stimulant drug
Press. p. 50. ISBN 0-674-83192-6. Warawa EJ, Mueller NJ (January 1975). "Quinuclidine Chemistry. 3. β-cis-2-(4'-Chlorobenzhydryl)-3-quinuclidinol, a New Central
AL-1095
Chemical compound
(TMEDA = N,N,N',N'-tetramethylethylenediamine) and thermally robust [GaH3(quinuclidine)]". Inorganic Chemistry. 30 (20): 3792–3793. doi:10.1021/ic00020a002
Gallane
Topics referred to by the same term
database now part of Grand dictionnaire terminologique 2-Butyl-3-(p-tolyl)quinuclidine, a stimulant drug The logical fallacy of Begging The Question The ICAO
BTQ_(disambiguation)
Discontinued drug for Alzheimer's Disease and Schizophrenia
Facinicline (development code RG3487) is a α7 nicotinic acetylcholine receptor partial agonist and antagonist to serotonin-3 receptors (5-HT3). It demonstrated
Facinicline
Veterinary medication
Maropitant , sold under the brand name Cerenia among others, when used as maropitant citrate (USAN), is a neurokinin-1 (NK1) receptor antagonist developed
Maropitant
Amineptine • Benzatropine (benztropine) • Bromantane • 2-Butyl-3-(p-tolyl)quinuclidine (BTQ) • BTS-74,398 • Bupropion (amfebutamone) • Ciclazindol • Diclofensine •
List_of_dopaminergic_drugs
Drug used in narrow angle glaucoma
between pK(a) and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction: discovery of quinuclidine as optimum catalyst leading to substantial
Aceclidine
Chemical compound
(February 2005). "Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors".
PNU-282,987
Basket-shaped ring molecule able to store other molecules within itself
found to accelerate the reaction rate of a Menshutkin reaction between quinuclidine and butylbromide by a factor of 1600. In heterocalixarenes the phenolic
Calixarene
C7H13N heptanenitrile 629–08–3 C7H13N methyldiallylamine 2424–01–3 C7H13N quinuclidine 100–76–5 C7H13NO cyclohexanecarboxamide 1122–56–1 C7H13NS hexyl isothiocyanate
List of compounds with carbon number 7
List_of_compounds_with_carbon_number_7
Chemical compound
Here’s an example of W2(O-t-Bu)6 reacting with EtC≡CCN in the presence of quinuclidine: W2(O−t−Bu)6 +EtC≡CCN + 12L → EtC≡CC≡W(O−t−Bu)3L + N≡W(O−t−Bu)3 On the
Hexa(tert-butoxy)ditungsten(III)
Hexa(tert-butoxy)ditungsten(III)
Chemical compound
Cinchonidine is an alkaloid found in Cinchona officinalis and Gongronema latifolium. It is used in asymmetric synthesis in organic chemistry. Cinchonine
Cinchonidine
Medical condition
between a propionate side chain of the porphyrin and the protonated quinuclidine nitrogen atom of either alkaloid. Due to the presence of the chlorine
Porphyria_cutanea_tarda
Trihalide and Borane Complexes of 1,4-Diazabicyclo[2.2.2]octane and Quinuclidine". Spectrochimica Acta Part A: Molecular Spectroscopy. 30: 1021. Bibcode:1974AcSpA
George_L._Humphrey
Measure of relative response to a drug
Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation"
Intrinsic_activity
Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library". Journal of Medicinal Chemistry.
List of miscellaneous 5-HT2A receptor agonists
List_of_miscellaneous_5-HT2A_receptor_agonists
Index of chemical compounds with the same molecular formula
mass: 111.18 g/mol, exact mass: 111.1048 u) may refer to: Pyrrolizidine Quinuclidine This set index page lists chemical structure articles associated with
C7H13N
Chemical compound
Dihydroquinine, also known as hydroquinine or DHQ, is an organic compound and as a cinchona alkaloid closely related to quinine. The specific rotation
Dihydroquinine
Chemical compound
Tabernanthine is an alkaloid found in Tabernanthe iboga. It has been used in laboratory experiments to study how addiction affects the brain. Tabernanthine
Tabernanthine
Chemical compound
Azasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27 It is used in the management of nausea and vomiting induced by cancer
Azasetron
Antiarrythmic medication
Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. It is a diastereomer of antimalarial agent quinine, originally derived
Quinidine
Chemical compound
5-thiadiazol-3-yl]quinuclidine Routes of administration oral ATC code None Identifiers IUPAC name (3S)-3-[4-(Butylsulfanyl)-1,2,5-thiadiazol-3-yl]quinuclidine CAS Number
Vedaclidine
Pharmaceutical compound
5-MeO-IsoqT, also known as 5-MeO-desethylisoquinuclidineT or as desethyl-17,18-secoibogaine, is a tryptamine derivative and a deconstructed and simplified
5-MeO-IsoqT
Chemical compound
Zacopride is a potent antagonist at the 5-HT3 receptor and an agonist at the 5-HT4 receptor. It has anxiolytic and nootropic effects in animal models,
Zacopride
Pharmaceutical compound
Eprenetapopt (APR-246) is an experimental anti-cancer drug which acts by reactivating certain mutant forms of p53, a tumour-suppressing gene which is commonly
Eprenetapopt
Chemical compound
Umeclidinium bromide, sold under the brand name Incruse Ellipta among others, is a long-acting muscarinic antagonist approved for the maintenance treatment
Umeclidinium_bromide
Type of cell receptor found in humans
TA, Johnson RT, Miller C (April 2005). "2-(Arylmethyl)-3-substituted quinuclidines as selective alpha 7 nicotinic receptor ligands". Bioorganic & Medicinal
Alpha-7_nicotinic_receptor
Pharmaceutical drug
Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is
Cevimeline
Chemical compound
Talsaclidine (WAL-2014) is a non-selective muscarinic acetylcholine receptor agonist which acts as a full agonist at the M1 subtype, and as a partial agonist
Talsaclidine
Chemical compound
Optochin (or ethylhydrocupreine hydrochloride) is a derivative of quinine introduced in 1911 by Morgenroth and Levy with the intention to treat pneumococci
Optochin
Nicotinic agonist medication
AQW-051 also known as VQW-765 is an orally available, highly selective partial agonist of the alpha-7 nicotinic receptor (nAChR) developed by Novartis
AQW-051
Pharmaceutical compound
Atumelnant (INNTooltip International Nonproprietary Name; developmental code name CRN04894) is an investigational new drug developed by Crinetics Pharmaceuticals
Atumelnant
Chemical compound
Mequitazine (trade name Primalan) is an H1 antagonist and anticholinergic of the phenothiazine chemical class. It is used to treat allergies and rhinitis
Mequitazine
Chemical compound
Bradanicline (INN; development code TC-5619) is a drug which was being developed by Targacept that acts as a partial agonist at the α7 subtype of the neural
Bradanicline
Pharmaceutical drug
Palonosetron, sold under the brand name Aloxi, is a medication used for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)
Palonosetron
Chemical compound
Tombozine is an alkaloid found in the plant species Vinca minor. The chemical has been found to have a sedative effect in mice and to lower blood pressure
Tombozine
Chemical compound
Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library". Journal of Medicinal Chemistry.
SCQ1
Chemical compound
Cinchonine is an alkaloid found in Cinchona officinalis. It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer
Cinchonine
Chemical compound
Aclidinium bromide (INN) is a long-acting, inhaled muscarinic antagonist (LAMA) approved in the United States in July 2012 as a maintenance treatment for
Aclidinium_bromide
Chemical compound
Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease. It made
Sabcomeline
Chemical compound
Dihydroquinidine (also called hydroquinidine) is an organic compound, a cinchona alkaloid closely related to quinine. The specific rotation is +226° in
Dihydroquinidine
Quinuclidones are a class of bicyclic organic compounds with chemical formula C7H11NO with two structural isomers for the base skeleton 3-quinuclidone
Quinuclidone
Chemical compound
PHA-543,613 is a drug that acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of
PHA-543,613
Tricyclic antidepressant
Quinupramine (brand names Kevopril, Kinupril, Adeprim, Quinuprine) is a tricyclic antidepressant (TCA) used in Europe for the treatment of depression.
Quinupramine
Chemical reaction
Wawzonek, S.; Thelan, M. F. Jr; Thelan, P. J. (1951). "Preparation of quinuclidines". J. Am. Chem. Soc. 73 (6): 2806–2808. Bibcode:1951JAChS..73.2806W.
Hofmann–Löffler_reaction
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List_of_MeSH_codes_(D03)
Chemical compound
CAR-301,060 (also known as cis-2-Methyl-3-quinuclidinylphenylcyclopentylglycolate or just by its code number 301060) is a potent and long lasting anticholinergic
CAR-301,060
Chemical compound
974; (2S,3S)-2-Diphenylmethyl-3-[(5-isopropyl-2-methoxybenzyl)amino]quinuclidine Routes of administration By mouth ATC code none Legal status Legal status
Ezlopitant
Chemical compound
RS-56812 is a potent and selective partial agonist at the 5HT3 receptor. It has been shown to improve performance on animal tests of memory. Its use in
RS-56812
Chemical reaction
(1989). "A short, stereospecific route to chiral trans-2,6-disubstituted quinuclidines". Tetrahedron Lett. 30 (43): 5825. doi:10.1016/S0040-4039(01)93481-1
Aza-Diels–Alder_reaction
Class of chemical compounds
varied tropane fragment like with exchanged heteroatom, trop-2-enes, quinuclidines, piperidines. "The methyl has to be at the other O, and trans" does
Phenyltropane
Chemical compound
Cefclidin (also known as cefclidin, cefaclidine, or E1040) is a cephalosporin antibiotic. Watanabe, N. A.; Katsu, K (1992). "Cefclidin (E1040), a novel
Cefclidin
QUINUCLIDINE
QUINUCLIDINE
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Boy/Male
Tamil
Yogender | யோகேஂதர
God of Yoga
Girl/Female
Arabic
Famous
Boy/Male
Tamil
Gold or silver coin
Girl/Female
English
meaning from Laurentium.
Surname or Lastname
English
English : habitational name from either of two places named Cudworth, in South Yorkshire and Somerset. The first element of the Yorkshire name is the Old English personal name Cūtha, that of the Somerset name the Old English personal name Cuda; the second element of both is Old English wor{dh} ‘enclosure’.
Girl/Female
Hebrew
Close to God.
Boy/Male
American, British, Chinese, Christian, English, German
Industrious Ruler; Emery's Son; Brave
Girl/Female
Hindu
Driving, Falcon, Long-legged, Spider
Boy/Male
Indian, Sanskrit
Bold; A Hero
Girl/Female
Tamil
Prayer, Request, Humility
QUINUCLIDINE
QUINUCLIDINE
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QUINUCLIDINE