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PDE4A

PDE4A

Protein-coding gene in the species Homo sapiens

5'-cyclic phosphodiesterase 4A is an enzyme that in humans is encoded by the PDE4A gene. The protein encoded by this gene belongs to the cyclic nucleotide

PDE4A

Phosphodiesterase 4

Index of chemical compounds with the same name

At least four types of the enzyme phosphodiesterase 4 (PDE4) are known: PDE4A PDE4B PDE4C PDE4D 3',5'-cyclic-AMP phosphodiesterase Phosphodiesterase (PDE)

Phosphodiesterase 4

Phosphodiesterase_4

PDE4 inhibitor

Class of chemical compounds

disease (COPD), asthma and rheumatoid arthritis. PDE4D inhibition, along with PDE4A inhibition also appears to be responsible for the antidepressant effects

PDE4 inhibitor

PDE4_inhibitor

Imperatorin

Chemical compound

phosphodiesterase PDE4. It displays a significant preference for PDE4B over PDE4A. Imperatorin has been shown to have anti-inflammatory activity in chondrocytes

Imperatorin

Cyclic nucleotide phosphodiesterase

Class of enzymes

this domain include: PDE1A, PDE1B, PDE1B2, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4B5, PDE4C, PDE4D, PDE5A, PDE6A, PDE6B, PDE6C, PDE7A, PDE7B,

Cyclic nucleotide phosphodiesterase

Cyclic_nucleotide_phosphodiesterase

PRKAR2A

Protein-coding gene in the species Homo sapiens

AKAP11, AKAP13, AKAP1, AKAP2, AKAP3, AKAP8, AKAP9, ARFGEF2, CBFA2T3 GSK3B, PDE4A, and RUNX1T1. Protein kinase AMPK cAMP GRCh38: Ensembl release 89: ENSG00000114302

PRKAR2A

Piclamilast

Chemical compound

Piclamilast functions through the selective inhibition of the four PDE4 isoforms (PDE4A-D). It shows no inhibition of the other PDEs. The PDE4 isoforms are especially

Piclamilast

List of human protein-coding genes 6

O00408 11859 PDE3A HGNC:8778; Q14432 11860 PDE3B HGNC:8779; Q13370 11861 PDE4A HGNC:8780; P27815 11862 PDE4B HGNC:8781; Q07343 11863 PDE4C HGNC:8782; Q08493

List of human protein-coding genes 6

List_of_human_protein-coding_genes_6