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NINJ1

  • NINJ1
  • Protein-coding gene in the species Homo sapiens

    encoded by the NINJ1 gene in humans. This transmembrane protein plays a critical role in plasma membrane rupture during lytic cell death. NINJ1 is involved

    NINJ1

    NINJ1

    NINJ1

  • PANoptosis
  • Inflammatory cell death pathway

    (HS), such as fever, during infection, and NINJ1 is a key executioner in this context. Deletion of NINJ1 in a murine model of HS and infection reduces

    PANoptosis

    PANoptosis

  • Chromosome 9
  • Human chromosome

    N(alpha)-acetyltransferase 35, NatC auxiliary subunit NANS: N-acetylneuraminate synthase NINJ1: ninjurin-1 NOL6: nucleolar protein 6 NUDT2: nudix hydrolase 2 OBP2B: encoding

    Chromosome 9

    Chromosome 9

    Chromosome_9

  • Hao Wu (biochemist)
  • Chinese American biochemist

    activates both cleaved and full-length GSDMD. They also discovered that NINJ1 mediates plasma membrane rupture by cleaving and releasing membrane discs

    Hao Wu (biochemist)

    Hao Wu (biochemist)

    Hao_Wu_(biochemist)

  • Pyroptosis
  • Type of programmed cell death

    cryo-electron microscopy (cryo-EM). Also in 2021, an additional molecule, NINJ1, was found to be required for the plasma membrane rupture during pyroptosis

    Pyroptosis

    Pyroptosis

  • Sebastian Hiller
  • German-Swiss structural biologist

    pyroptosis and chronic inflammation. Recent findings showed that the protein NINJ1 plays an important role in inflammatory reactions in the body and forms

    Sebastian Hiller

    Sebastian Hiller

    Sebastian_Hiller

  • Vishva Dixit
  • Kenyan molecular biologist

    septic shock. Using a similar research strategy, in 2021, they reported NINJ1 to be a mediator of plasma membrane rupture and DAMP release from pyroptotic

    Vishva Dixit

    Vishva Dixit

    Vishva_Dixit

  • Thirumala-Devi Kanneganti
  • Indian immunologist

    role of NINJ1, a key executioner of inflammatory cell death, in mediating PANoptosis following heat stress and infection, thereby identifying NINJ1 and PANoptosis

    Thirumala-Devi Kanneganti

    Thirumala-Devi Kanneganti

    Thirumala-Devi_Kanneganti

  • FAM120AOS
  • Protein-coding gene in the species Homo sapiens

    FAM120AOS on chromosome 9 are FGD3, SUSD, C9orf89, WNK2, C9orf129, and NINJ1. The genes found downstream from FAM120AOS on chromosome 9 are FAM120A and

    FAM120AOS

    FAM120AOS

    FAM120AOS

  • Biozentrum University of Basel
  • Division of the University of Basel

    Christian; Broz, Petr; Hiller, Sebastian (17 May 2023). "Structural basis of NINJ1-mediated plasma membrane rupture in cell death". Nature. 618 (7957). doi:10

    Biozentrum University of Basel

    Biozentrum University of Basel

    Biozentrum_University_of_Basel

  • List of human protein-coding genes 5
  • Q9BYG3 10531 NIM1K HGNC:28646; Q8IY84 10532 NIN HGNC:14906; Q8N4C6 10533 NINJ1 HGNC:7824; Q92982 10534 NINJ2 HGNC:7825; Q9NZG7 10535 NINL HGNC:29163; Q9Y2I6

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

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Online names & meanings

  • Sewald
  • Boy/Male

    American, British, English

    Sewald

    Sea Powerful

  • Prologue
  • Boy/Male

    Shakespearean

    Prologue

    A Midsummer Night's Dream' Quince, a carpenter, acts as Prologue in the play within the play.

  • Amaanya | அமாந்யா 
  • Girl/Female

    Tamil

    Amaanya | அமாந்யா 

    Unknown

  • Boc
  • Boy/Male

    American, British, English

    Boc

    Male Deer

  • Baka | பகா
  • Girl/Female

    Tamil

    Baka | பகா

    Crane

  • Alfeo
  • Boy/Male

    British, English

    Alfeo

    Counsel from the Elves

  • Bearer
  • Surname or Lastname

    English

    Bearer

    English : unexplained.

  • Vybhav
  • Boy/Male

    Indian

    Vybhav

    Over Perfection

  • Micky
  • Boy/Male

    Hebrew

    Micky

    Who is like God? Gift from God. In the Bible, St. Michael was the conqueror of Satan and patron...

  • Hitansi
  • Girl/Female

    Indian

    Hitansi

    Simplicity and purity

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