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NEDD1

NEDD1

Protein-coding gene in the species Homo sapiens

developmentally down-regulated 1, also known as Nedd1, is a human gene and encodes the protein NEDD1. NEDD1 is localized in the centrosome and it plays a

NEDD1

Pericentriolar material

receptor associated protein 2, binds gTubRCs that nucleate microtubules NEDD1, binds gTubRCs that stabilise microtubules Gamma Tubulin, nucleates microtubules

Pericentriolar material

Pericentriolar_material

Microtubule nucleation

Filament Formation

functions and regulatory proteins, such as components of the Ran cycle. NEDD1 recruits the γ-TuRC to the centrosome by binding to γ-tubulin. Job D, Valiron

Microtubule nucleation

Microtubule_nucleation

TUBG1

Tubulin protein

F, Liu J, Jiang Q, Zhang C (July 2009). "Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome"

TUBG1

WD40 repeat

Short protein motif that forms a solenoid domain

LRBA, LRRK1, LRRK2, LRWD1, LYST, MAPKBP1, MED16, MORG1, NBEA, NBEAL1, NEDD1, NLE1, NSMAF, NUP37, NUP43, NWD1, PAAF1, PAFAH1B1, PAK1IP1, PEX7, PHIP,

WD40 repeat

WD40_repeat

Mosaic variegated aneuploidy syndrome

Medical condition

CH; Zhang, Bo; Teng, Junlin; Chen, Jianguo (September 2012). "Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole

Mosaic variegated aneuploidy syndrome

Mosaic_variegated_aneuploidy_syndrome

List of human protein-coding genes 5

10406 NECTIN3 HGNC:17664; Q9NQS3 10407 NECTIN4 HGNC:19688; Q96NY8 10408 NEDD1 HGNC:7723; Q8NHV4 10409 NEDD4 HGNC:7727; P46934 10410 NEDD4L HGNC:7728;

List of human protein-coding genes 5

List_of_human_protein-coding_genes_5

HSPA1B

Human gene

DNAJC9, FOXP3, HDAC4, HOPX, HSP40, HSP90, HSP105, IRAK1BP1, METTL21A, NAA10, NEDD1, NOD2, PPP5C, PKRN, SMAD3, STUB1, TERT, TRIM5, TSC2, Heat shock proteins

HSPA1B