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Protein-coding gene in the species Homo sapiens
Nebulin is an actin-binding protein which is localized to the thin filament of the sarcomeres in skeletal muscle. Nebulin in humans is coded for by the
Nebulin
Protein-coding gene in the species Homo sapiens
belonging to the nebulin family of proteins. It is encoded by the NEBL gene. This family is composed of 5 members: nebulette, nebulin, N-RAP, LASP-1 and
Nebulette
Ionic compound (NaF)
"Sarcomere matrix of striated muscle: In vivo phosphorylation of titin and nebulin in mouse diaphragm muscle". Archives of Biochemistry and Biophysics. 262
Sodium_fluoride
Repeating unit of a myofibril in a muscle cell
as blueprint for the assembly of the sarcomere. Another giant protein, nebulin, is hypothesised to extend along the thin filaments and the entire I-Band
Sarcomere
Medical condition
most common genetic form of NM is caused by a mutation in the nebulin gene, called Nebulin, and has a range of severity levels. All published cases up to
Nemaline_myopathy
Contractile element of muscle
filaments. Thin filaments consist primarily of the protein actin, coiled with nebulin filaments. Actin, when polymerized into filaments, forms the "ladder" along
Myofibril
Protein-coding gene in the species Homo sapiens
Nebulin-related-anchoring protein (N-RAP) is a protein that in humans is encoded by the NRAP gene. N-RAP is a muscle-specific isoform belonging to the
NRAP
Protein-coding gene in the species Homo sapiens
family of giant sarcomeric signaling proteins that includes titin and nebulin. Obscurin is expressed in cardiac and skeletal muscle, and plays a role
Obscurin
Taiwanese biochemist
previously unrecognized high molecular weight proteins of myofibrils, Titin and Nebulin, which fundamentally changed our understanding of muscle sarcomeres. At
Kuan_Wang
Nutritional physiology researcher
Kuan Wang. "Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope
Marlena_Kruger
Topics referred to by the same term
reaction paths in computational chemistry N-Ethylbuphedrone, a stimulant Nebulin, a large protein found in muscles Neb (or Nebuchadnezzar), a character
NEB
Long chain of protein monomers
of the actin filaments causing the overall stability of the structure. Nebulin is another protein that can bind to the sides of the actin preventing the
Protein_filament
Protein-coding gene in the species Homo sapiens
proline-rich domain. Myopalladin binds the Src homology domain of nebulette and nebulin and tethers it to alpha-actinin via its C-terminal domain binding to the
Myopalladin
Protein-coding gene in the species Homo sapiens
muscles. The mice in this study were born with high nebulin levels in their skeletal muscle but nebulin expression rapidly fell within weeks after birth
SBK3
Anime convention series in the United States
Matt Greenfield, Mike McFarland, Kevin McKeever, Chris Patton, phoenix/NEBULIN, Sean Schemmel, Select Start, Mike Sinterniklaas, Doug Smith, Team Ryouko
Kunicon
Protein-coding gene in humans
(ILK) and beta1-spectrin; intercalated discs, where it associates with the nebulin-related anchoring protein (NRAP); nucleus, where it binds to the transcription
CSRP3
Protein
Causative mutations have been detected in skeletal α-actinin, tropomyosin, nebulin, and troponin. Within humans, mutations in both the γ-Tropomyosin and β-Tropomyosin
Tropomyosin
Protein-coding gene in humans
at the Z-disc, and form CapZ. CapZ interacts with α-actinin, nebulette, nebulin, HSC70. at the Z-disc. CAPZB is a member of the F-actin capping protein
CAPZB
Protein-coding gene in the species Homo sapiens
N, VanLoock MS, Orlova A, et al. (2002). "Each actin subunit has three nebulin binding sites: implications for steric blocking". Curr. Biol. 12 (5): 383–8
Alpha-actinin-4
Protein-coding gene in the species Homo sapiens
McElhinny AS, Kolmerer B, Fowler VM, et al. (2001). "The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments"
Tropomodulin_4
German structural biochemist
sarcomeric components. The group also determined the first structure of native nebulin bound to actin thin filaments within intact sarcomeres at 4.5 Å resolution
Stefan_Raunser
Protein-coding gene in the species Homo sapiens
McElhinny AS, Kolmerer B, Fowler VM, et al. (2001). "The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments"
Tropomodulin_1
Class of proteins
Myelin basic protein Naphthylphthalamic acid binding protein (NPA) N-RAP Nebulin N-WASP Neurabin Nullo Neurexins Neurocalcin Nexillin OYE2 Palladin Plastin
Actin-binding_protein
Protein found in humans
134-141, 514-522 Cullen Family Profile 443-552 K-Box Domain Profile 526-619 Nebulin Repeat Profile 521-531 Serine Rich Region 710-747 Rad50 zinc-hook domain
CCDC186
Protein found in humans
Cells with bbc1 gene deletion are viable. Bbc1 is affinity captured by the Nebulin-family actin filament anchoring protein Cyk3 and the SMARCAD1 family ATP-dependent
60S_ribosomal_protein_L13
NEBULIN
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Boy/Male
Latin
Bean farmer.
Female
Serbian
(Славица) Serbian name SLAVICA means "glory."
Girl/Female
Indian, Punjabi, Sikh
Throughout the Ages - Reference to Time
Boy/Male
Latin English
Merciful.
Boy/Male
Indian
Respectable Man, Intelligent
Male
Babylonian
, a king of the country of Cindutausi.
Girl/Female
Hindu
Talent, Great conquer
Boy/Male
Arabic, Muslim, Pashtun
Felicities; Good Fortune
Boy/Male
Indian, Sanskrit
Permanent; Unfailing
Surname or Lastname
English
English : from the Old Norse byname Krókr meaning ‘crook’, ‘bend’, originally possibly bestowed on a cripple or hunchback or a devious schemer, but in early medieval England used as a personal name.English : from Old Norse krókr ‘hook’, ‘bend’, borrowed into Middle English as a vocabulary word and applied as a metonymic occupational name for a maker, seller, or user of hooks or a topographic name for someone who lived by a bend in a river or road. In some instances the surname may have arisen as a habitational name from places in Cumbria and Durham named Crook from this word.
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