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Disease that damages the myelin sheaths around nerves
Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks myelin, the insulating cover of nerve cells in the human body, causing
Multiple_sclerosis
Atypical multiple sclerosis lesions
Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics
Tumefactive multiple sclerosis
Tumefactive_multiple_sclerosis
Approaches to managing the disease
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS). Several therapies for it exist,
Management of multiple sclerosis
Management_of_multiple_sclerosis
American nonprofit organization
The National Multiple Sclerosis Society (NMSS) is an American nonprofit organization founded in 1946. It is dedicated to supporting individuals affected
National Multiple Sclerosis Society
National_Multiple_Sclerosis_Society
Disease pathology and physiology
Multiple sclerosis is an inflammatory demyelinating disease of the CNS in which activated immune cells invade the central nervous system and cause inflammation
Pathophysiology of multiple sclerosis
Pathophysiology_of_multiple_sclerosis
Topics referred to by the same term
Multiple Sclerosis Society may refer to: The Multiple Sclerosis Society of Great Britain The Multiple Sclerosis Society of Canada The National Multiple
Multiple_Sclerosis_Society
Neurological signs and symptoms
Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia)
Signs and symptoms of multiple sclerosis
Signs_and_symptoms_of_multiple_sclerosis
Current standards for diagnosing multiple sclerosis (MS) are based on the 2018 revision of McDonald criteria. They rely on MRI detection (or clinical demonstration)
Diagnosis of multiple sclerosis
Diagnosis_of_multiple_sclerosis
Medical condition
acute multiple sclerosis, also known as Marburg multiple sclerosis or acute fulminant multiple sclerosis, is considered one of the multiple sclerosis borderline
Marburg acute multiple sclerosis
Marburg_acute_multiple_sclerosis
Pathologic overview
Multiple sclerosis (MS) can be pathologically defined as the presence of distributed glial scars (scleroses) in the central nervous system that must show
Pathology of multiple sclerosis
Pathology_of_multiple_sclerosis
This is a list of notable people with multiple sclerosis. Multiple sclerosis is a demyelinating disease in which the insulating covers of nerve cells in
List of people with multiple sclerosis
List_of_people_with_multiple_sclerosis
Research in multiple sclerosis may find new pathways to interact with the disease, improve function, curtail attacks, or limit the progression of the underlying
Research in multiple sclerosis
Research_in_multiple_sclerosis
Stiffening of a tissue or anatomical feature
disease that most often affects the vulva and the penis. Multiple sclerosis, or focal sclerosis, is a central nervous system disease which affects coordination
Sclerosis_(medicine)
Human disease
often grouped together under Multiple Sclerosis. They are sometimes considered different diseases from Multiple Sclerosis, but considered by others to
Inflammatory demyelinating diseases of the central nervous system
Inflammatory_demyelinating_diseases_of_the_central_nervous_system
Several biomarkers for diagnosis of multiple sclerosis, disease evolution and response to medication (current or expected) are under research. While most
Biomarkers of multiple sclerosis
Biomarkers_of_multiple_sclerosis
Research in Multiple Sclerosis (ECTRIMS) Patient Advocacy Organization: Multiple Sclerosis International Federation European Multiple Sclerosis Platform
List of multiple sclerosis organizations
List_of_multiple_sclerosis_organizations
Pharmaceutical drug
treatment of adults with highly active forms of relapsing-remitting multiple sclerosis. Cladribine is a purine analogue that selectively targets and suppresses
Cladribine
Medical condition
similar to aggressive forms of multiple sclerosis. Although historically considered rare, with fewer than 1% of multiple sclerosis cases showing the characteristic
Baló_concentric_sclerosis
Medication used to treat multiple sclerosis and Crohn's disease
the brand name Tysabri among others, is a medication used to treat multiple sclerosis and Crohn's disease. It is a humanized monoclonal antibody against
Natalizumab
Central nervous system disease
include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies
Neurodegenerative_disease
Australian non-profit organization
Multiple Sclerosis Australia, or MS Australia, is a national non-profit organization in Australia that coordinates and allocates funds for multiple sclerosis
Multiple_Sclerosis_Australia
Hematologist, clinician-scientist
pioneering work on hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) and other severe autoimmune diseases. Based at Careggi University
Riccardo_Saccardi
Significant disability caused by MS
Malignant multiple sclerosis is used to describe MS patients who reach significant level of disability in a short period of time. Malignant MS cases are
Malignant_multiple_sclerosis
Academic journal
The Multiple Sclerosis Journal (formerly Multiple Sclerosis) is a monthly peer-reviewed medical journal covering the clinical neurology of multiple sclerosis
Multiple_Sclerosis_Journal
Overview article
There are several ways for pharmaceuticals for treating multiple sclerosis (MS) to reach the market. Novel pharmaceuticals cannot enter the US market without
Multiple sclerosis drug pipeline
Multiple_sclerosis_drug_pipeline
Episodes of uncontrollable crying or laughing
attention deficit hyperactivity disorder (ADHD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). It has been
Pseudobulbar_affect
Marker in blood/cerebrospinal fluid testing
in the CSF of more than 95% of patients with clinically definite multiple sclerosis. Two methods of analysis are possible: (a) protein electrophoresis
Oligoclonal_band
Australian doctor
evaluates modifiable risk factors that predict the progression of Multiple sclerosis. He has served since 2017 as the Chief Editor for Neuroepidemiology
George_Jelinek
Rare neurodegenerative disease
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a rare terminal neurodegenerative disease defined
ALS
MS Focus: The Multiple Sclerosis Foundation, also known as the Multiple Sclerosis Foundation or just MS Focus, is a 501(c)(3) non-profit organization
Multiple_Sclerosis_Foundation
Disorders of adaptive immune system
bowel diseases (such as Crohn's disease and ulcerative colitis), multiple sclerosis, alopecia areata, Addison's disease, pernicious anemia, psoriasis
Autoimmune_disease
Wakefulness-promoting medication
common and often debilitating symptom experienced by people with multiple sclerosis. Reviews and meta-analyses of controlled trials have found that modafinil
Modafinil
American neurologist and neuroimmunologist (born c. 1956)
in St. Louis School of Medicine and co-directs the John L Trotter Multiple Sclerosis Clinic at Barnes-Jewish Hospital. Cross is a leader in the field of
Anne_Haney_Cross
Pseudoscientific alternative medical therapy using bee products
including several types of arthritis; neurological problems such as multiple sclerosis, lower back pain and migraine headaches; and skin conditions such
Apitherapy
American pharmaceutical company
beta-1a (Plegridy), and natalizumab (Tysabri), all for the treatment of multiple sclerosis (collectively 45% of 2024 revenues); nusinersen (Spinraza) for the
Biogen
Virus of the herpes family
active US military over 20 years suggested EBV as the leading cause of multiple sclerosis (MS), with a recent EBV infection causing a 32-fold increase in MS
Epstein–Barr_virus
The Multiple Sclerosis Functional Composite (MSFC) is a clinical trial outcome measure of assessing the severity of multiple sclerosis primarily used in
Multiple sclerosis functional composite
Multiple_sclerosis_functional_composite
Reversal of sleeping tendencies
patients' circadian rhythm. In neuroinflammatory conditions such as Multiple Sclerosis, sleep inversion arises due to alterations in sleep architecture,
Sleep_inversion
Natural partial recreation of myelin sheaths in the brain
the hope of finding treatments for demyelinating diseases, such as multiple sclerosis. As of 2022 the status of possible remyelination acceleration is of
Remyelination
Spanish athlete
with multiple sclerosis, with an extraordinary story of personal improvement, which was made into a film in 2016. After he was diagnosed with multiple sclerosis
Ramón_Arroyo_(athlete)
Medical diagnostic method
(PASAT). The subjects are given in the version used as part of the Multiple Sclerosis Functional Composite a number every 3 seconds and are asked to add
Paced Auditory Serial Addition Test
Paced_Auditory_Serial_Addition_Test
Intense feelings of well-being
following the migraine episode. Euphoria sometimes occurs in persons with multiple sclerosis as the illness progresses. This euphoria is part of a syndrome originally
Euphoria
Inflammation of nervous tissue
lateral sclerosis". Journal of Neuroimmunology. 235 (1–2): 104–109. doi:10.1016/j.jneuroim.2011.03.011. PMID 21501881. S2CID 30757392. "Multiple Sclerosis: Hope
Neuroinflammation
vitamin D can result in "growth retardation and skeletal deformities." Multiple sclerosis (MS) is least prevalent in the sunniest regions. According to a study
Health effects of sunlight exposure
Health_effects_of_sunlight_exposure
British neurologist (1890–1981)
multiple sclerosis. His book Multiple sclerosis, published first time in 1955, has since his death been published with the title McAlpine's Multiple Sclerosis
Douglas_McAlpine
Pharmaceutical compound
GM-CSF has been shown to be involved in autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) in which cases GM-CSF levels are
Otilimab
Dutch mystic (1380-1433)
nose. Today, some posit that Saint Lidwina is one of the first known multiple sclerosis patients and attribute her disability to the effects of the disease
Lidwina
Neuropsychiatrist
neuropsychiatrist. His research and clinical work focuses on people with multiple sclerosis, traumatic brain injury and Conversion Disorder. He has undertaken
Anthony_Feinstein
American actress (born 1981)
2018. In January 2016, Sigler revealed that she was diagnosed with multiple sclerosis (MS) when she was 20 years old. In 2000, while filming Campfire Stories
Jamie-Lynn_Sigler
Disorder impairing normal brain function
because of years of misdiagnosis and accusations of malingering. Multiple sclerosis has some overlapping symptoms with FNSD, potentially a source of misdiagnosis
Functional neurological symptom disorder
Functional_neurological_symptom_disorder
Protein-coding gene in the species Homo sapiens
Certain HLA-DQB1 alleles are also linked to a modest increased risk of multiple sclerosis. Other HLA-DQB1 alleles are associated with a predisposition to narcolepsy
HLA-DQB1
Clinical situation indicative of possible multiple sclerosis
situation in which a person has white matter lesions suggestive of multiple sclerosis (MS), as shown on an MRI scan that was done for reasons unrelated
Radiologically isolated syndrome (multiple sclerosis)
Radiologically_isolated_syndrome_(multiple_sclerosis)
Mammalian protein found in Homo sapiens
for multiple sclerosis. Genomic region containing the single-nucleotide polymorphism rs1335532, associated with high risk of multiple sclerosis, has
CD58
Class of immunosuppressive drug
a TNF-alpha inhibitor prototype, Lenercept, for the treatment of multiple sclerosis (MS). However, the patients in the study who received the drug had
TNF_inhibitor
Chemical compound and essential nutrient
health, and as 300 mg per day as a possibly effective treatment for multiple sclerosis (see § Research). Overconsumption of 5 mg/day or higher causes elevated
Biotin
Medical specialty that focuses on the design and application of orthoses
system (e.g. cerebral palsy, traumatic brain injury, stroke, and multiple sclerosis) can cause incorrect motor impulses that often result in clearly visible
Orthotics
neurodegenerative diseases, particularly multiple sclerosis, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). His work extensively utilizes longitudinal
Alberto_Ascherio
Cellular response to brain injury involving glial cells
multiple system atrophy, prion disease, multiple sclerosis, AIDS dementia complex, vasculitis, Parkinson's disease, amyotrophic lateral sclerosis, and
Gliosis
Organic chemical that functions both as a hormone and a neurotransmitter
that dopamine imbalance influences the fatigue in multiple sclerosis. In patients with multiple sclerosis, dopamine inhibits production of IL-17 and IFN-γ
Dopamine
Immunologist and neurologist, professor of pediatrics
how the immune system attacks the brain, specifically in cases of multiple sclerosis (MS), motor neuron disease (ALS), and neuromyelitis optica (NMO).
Lawrence_Steinman
Effects of vitamin D on the nervous system
neuropsychiatric disorders, including Alzheimer's disease, autism, epilepsy, multiple sclerosis, Parkinson's disease, and schizophrenia. Vitamin D (the inactive version)
Vitamin_D_and_neurology
American football player (born 2003)
National Multiple Sclerosis Society, and his mother, Elsa, lives with multiple sclerosis. Mendoza, alongside his brother, has created multiple menu items
Fernando_Mendoza
Acute inflammation diseases of the optic nerve and spinal cord
formal loss of visual acuity. Compared to idiopathic ON and ON due to multiple sclerosis (MS), ON due to NMOSD more often results in severe visual loss at
Neuromyelitis optica spectrum disorder
Neuromyelitis_optica_spectrum_disorder
Worsening of neurologic symptoms in multiple sclerosis caused by heat
and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated
Uhthoff's_phenomenon
Multiple Sclerosis Discovery Forum (MSDF) is a non-profit online resource created to speed progress toward a cure for multiple sclerosis (MS) and other
Multiple Sclerosis Discovery Forum
Multiple_Sclerosis_Discovery_Forum
State of tiredness, exhaustion or loss of energy
[citation needed] autoimmune diseases, such as celiac disease, lupus, multiple sclerosis, myasthenia gravis, NMOSD, Sjögren's syndrome, rheumatoid arthritis
Fatigue
American actor (1947–2020)
Laverne & Shirley. He served as a goodwill ambassador for the National Multiple Sclerosis Society. David Leonard Landau was born on June 22, 1947, in Brooklyn
David_Lander
Convergence of pathology with physiology
leading to changes in the heart muscle itself. The pathophysiology of multiple sclerosis (MS) is that of an inflammatory demyelinating disease in which activated
Pathophysiology
Pediatric neurologist and academic
University of Pennsylvania. Banwell is the co-director of the Pediatric Multiple Sclerosis and Neuroinflammatory Disorders Clinic at the Children's Hospital
Brenda_Banwell
Artificial miniature brain like organ
insight into dysregulation of genes responsible for tumor development. Multiple sclerosis is an auto-immune inflammatory disorder affecting the central nervous
Cerebral_organoid
British sprinter (born 1996)
In August 2022, Nielsen disclosed that she had been diagnosed with multiple sclerosis in the summer of 2021. Her twin sister Lina had been diagnosed with
Laviai_Nielsen
Pain affecting the somatosensory nervous system
underlying conditions such as primary presentation of a tumor or multiple sclerosis. Quantitative sensory testing (QST), a system of detailed analysis
Neuropathic_pain
Inflammation of the optic nerve
ON and "atypical" ON. The most commonly considered etiologies are multiple sclerosis (MS), neuromyelitis optica (NMO) / neuromyelitis optica spectrum disorder
Optic_neuritis
Chemical compound
It has also been used as a drug, to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults
4-Aminopyridine
Inflammation of the entire cross-section of the spinal cord
autoimmunity, and when it appears in multiple sclerosis (MS) cases, it's often misdiagnosed as multiple sclerosis (MS) or seen as a type of MS. But NMO
Transverse_myelitis
The Multiple Sclerosis International Federation (MSIF) was established in 1967 as an international body linking the activities of various national MS societies
Multiple Sclerosis International Federation
Multiple_Sclerosis_International_Federation
Dizziness with sensation of moving or surrounding objects moving
neuritis. Less common causes include stroke, brain tumors, brain injury, multiple sclerosis, migraines, trauma, and uneven pressures between the middle ears.
Vertigo
Degeneration of the upper motor neurons, causing muscle weakness
Primary lateral sclerosis (PLS) is a very rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs
Primary_lateral_sclerosis
Human disease involving inability to control defecation
constipation. It is common in people with spinal cord injury (SCI), multiple sclerosis (MS) or spina bifida. The gastrointestinal tract (GI tract) has a
Neurogenic_bowel_dysfunction
Experimental drug
currently undergoing Phase III clinical trials for the treatment of multiple sclerosis and has shown promise in treating various autoimmune disorders. Fenebrutinib
Fenebrutinib
American singer (born 1971)
as Mike Bass. He started having back spasms and was diagnosed with multiple sclerosis during his time with the group. He continued singing with the group
Michael_McCary
British health charity
The Multiple Sclerosis Trust (MS Trust) is an independent, national UK charity that was established in 1993. The MS Trust works to provide information
Multiple_Sclerosis_Trust
Immune response against an organism's own healthy cells
arthritis, ankylosing spondylitis, polymyositis, dermatomyositis, and multiple sclerosis. Autoimmune diseases are very often treated with steroids. Autoimmunity
Autoimmunity
Anti-CD20 monoclonal antibody
the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis. It is a humanized anti-CD20 monoclonal antibody. It targets CD20
Ocrelizumab
Organic compound involved in immune responses
production.[medical citation needed] Histamine therapy for treatment of multiple sclerosis is currently being studied. The different H receptors have been known
Histamine
Presence of cells originating from another individual
women suffering from autoimmune disorders (e.g. rheumatoid arthritis, multiple sclerosis) improves during pregnancy. These changes in immune responses during
Microchimerism
First Lady of Maryland since 2023
and First Family in Annapolis, Maryland. Moore was diagnosed with multiple sclerosis (MS) in her late twenties. She controlled the disease with medication
Dawn_Moore
American actress
she was a vegan. According to her mother, Cybill Shepherd, Ford has multiple sclerosis. In 2000, Ford married Canadian actor Chad Todhunter. They divorced
Clementine_Ford
2024 American film by Ron Howard
focuses on writing his manifesto, while Dore resolves to cure her multiple sclerosis through meditation. Their solitude, however, is short lived. They
Eden_(2024_film)
American actress (1944–2024)
(1997–98). In 2002, Garr announced that she had been diagnosed with multiple sclerosis, the symptoms of which had affected her ability to perform. She retired
Teri_Garr
Medical procedure to replace blood or immune stem cells
deficiency syndromes Autoimmune diseases, including multiple sclerosis Many recipients of HSCTs are multiple myeloma or leukemia patients who would not benefit
Hematopoietic stem cell transplantation
Hematopoietic_stem_cell_transplantation
Collection of molecular regulators
artificial neural networks with a hidden layer. There are three classes of multiple sclerosis: relapsing-remitting (RRMS), primary progressive (PPMS) and secondary
Gene_regulatory_network
Viral elements in human DNA
Gammaretrovirus. HERV-W was discovered because of its connection to multiple sclerosis (MS). In macrophage cell cultures of patients with MS, several retroviral-like
Human_endogenous_retrovirus-W
self-administered, targeted B-cell therapy for patients with relapsing multiple sclerosis" (Press release). Novartis. 20 August 2020. Archived from the original
List of therapeutic monoclonal antibodies
List_of_therapeutic_monoclonal_antibodies
American actress (born 1971)
musical revival Sweet Charity (2005). After being diagnosed with multiple sclerosis in August 2021, Applegate announced she would step away from appearing
Christina_Applegate
Integrin dimer
knocked out in mice, it resulted in an embryonic lethal mutation. In multiple sclerosis (MS), the VLA-4 integrin is essential in the processes by which T-cells
VLA-4
Paralysis of all four limbs and torso
injury), disease (such as transverse myelitis, Guillain–Barré syndrome, multiple sclerosis, or polio), or congenital disorders (such as muscular dystrophy).
Tetraplegia
Off-label, experimental use of the drug
has been studied for the treatment of multiple chronic pain conditions, including fibromyalgia, multiple sclerosis, Crohn's disease, long COVID, and complex
Low-dose_naltrexone
English rock musician (1946–1997)
bands and pursuing a solo career. In 1977, he was diagnosed with multiple sclerosis. He was supported by charity projects and financial contributions
Ronnie_Lane
Any neurological disease in which the myelin sheath of neurons is damaged
dysmyelinating diseases. In the most well-known demyelinating disease, multiple sclerosis, evidence suggests that the body's immune system plays a significant
Demyelinating_disease
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
Boy/Male
Hebrew Spanish
God will multiply.
Boy/Male
Australian, Vietnamese
Many; Multiple
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hindu, Indian
Un Countable; Multiple; Countless
Boy/Male
Hebrew American Latin
God will multiply.
Boy/Male
Hebrew Gaelic
God will multiply.
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew
God will multiply.
Girl/Female
Hebrew
God will multiply.
Boy/Male
Muslim
Multiple lights. Luster.
Girl/Female
Hebrew
God will multiply.
Boy/Male
Dutch, German, Hebrew
God will Multiply
Boy/Male
Hindu, Indian, Tamil
Multiple
Girl/Female
Hebrew
God will multiply.
Girl/Female
Hebrew
God will multiply.
Boy/Male
Hebrew
God shall multiply.
Boy/Male
Hebrew Spanish
God will multiply.
Boy/Male
Hebrew
God will multiply.
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
Boy/Male
German
Illustrious warrior. Army. Bright. Introduced into Britain during the Norman Conquest. Famous...
Girl/Female
Indian, Sanskrit
Friend of Devayani; Wife of King Kacha
Boy/Male
Arabic, Muslim
Worshipper of God; God Knows
Boy/Male
Irish Scottish
Serves Saint Bridget.
Girl/Female
Tamil
Elf counsel
Girl/Female
Gujarati, Hindu, Indian, Kannada, Sanskrit, Tamil, Telugu
Horse of Brightness
Girl/Female
Tamil
Who wants good for every one, Lovable
Boy/Male
Hindu, Indian, Tamil
Lord Krishna
Boy/Male
Muslim
Moon glow, Star, Moon light
Girl/Female
French
Victorious.
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
n.
The multiplier.
a.
Tending to multiply; having the power to multiply, or incease numbers.
n.
A quantity containing another quantity a number of times without a remainder.
n.
One who, or that which, multiplies or increases number.
v. t.
To add (any given number or quantity) to itself a certain number of times; to find the product of by multiplication; thus 7 multiplied by 8 produces the number 56; to multiply two numbers. See the Note under Multiplication.
a.
Having many flues; as, a multiflue boiler. See Boiler.
v. i.
To increase amount of gold or silver by the arts of alchemy.
a.
Containing more than once, or more than one; consisting of more than one; manifold; repeated many times; having several, or many, parts.
imp. & p. p.
of Multiply
n.
The number by which another number is multiplied. See the Note under Multiplication.
adv.
So as to multiply.
v. t.
To redouble; to multiply; to repeat.
v. t.
To multiply; to make manifold.
n.
The number which is to be multiplied by another number called the multiplier. See Note under Multiplication.
v. t.
To multiply; to increase.
v. i.
To increase in extent and influence; to spread.
n.
The number by which another number is multiplied; a multiplier.
a.
Manifold; multiple.
n.
Multiplied diversity.
p. pr. & vb. n.
of Multiply