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Topics referred to by the same term
Look up monogenic in Wiktionary, the free dictionary. Monogenic may refer to: Monogenic disorder, disease, inheritance, or trait, a single gene disorder
Monogenic
Health problem from genome abnormalities
abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality. Although
Genetic_disorder
Type of system in classical mechanics
In classical mechanics, a physical system is termed a monogenic system if the force acting on the system can be modelled in a particular, especially convenient
Monogenic_system
In mathematics, a monogenic field is an algebraic number field K for which there exists an element a such that the ring of integers OK is the subring
Monogenic_field
A monogenic function is a complex function with a single finite derivative. More precisely, a function f ( z ) {\displaystyle f(z)} defined on A ⊆ C {\displaystyle
Monogenic_function
Autism associated with another medical condition
etiology is known. Monogenic disorders are one of the causes of syndromic autism, which in this case are also known as monogenic autism spectrum disorders
Syndromic_autism
Medical condition
Along with neonatal diabetes, MODY is a form of the conditions known as monogenic diabetes. While the more common types of diabetes (especially type 1 and
Maturity-onset diabetes of the young
Maturity-onset_diabetes_of_the_young
Polynomial with 1 as leading coefficient
In algebra, a monic polynomial is a non-zero univariate polynomial (that is, a polynomial in a single variable) in which the leading coefficient (the coefficient
Monic_polynomial
Obesity caused by a mutation in a single gene
Monogenic obesity is excess weight caused by a mutation in a single gene. It differs from syndromic obesity, which involves additional clinical phenotypes
Monogenic_obesity
Inherited characteristic of an organism
A phenotypic trait, simply trait, or character state is a distinct variant of a phenotypic characteristic of an organism; it may be either inherited or
Phenotypic_trait
Semigroup generated by a single element
mathematics, a monogenic semigroup is a semigroup generated by a single element. Monogenic semigroups are also called cyclic semigroups. The monogenic semigroup
Monogenic_semigroup
Mental disorder with psychotic symptoms
diagram showing overlapping clinical phenotypes in genes associated with monogenic forms of autism spectrum disorder (ASD), dystonia, epilepsy and schizophrenia:
Schizophrenia
Progressive neurodegenerative disease
genetic disease, as rare inherited gene variants have been firmly linked to monogenic PD, and most cases carry variants that increase PD risk. PD heritability
Parkinson's_disease
Rare neurodegenerative disease
ALS is thought to account for 10–15% of cases overall and can include monogenic, oligogenic, and polygenic modes of inheritance. There is considerable
ALS
Group of endocrine diseases characterized by high blood sugar levels
diabetes can result from other specific causes, such as genetic conditions (monogenic diabetes syndromes like neonatal diabetes and maturity-onset diabetes
Diabetes
Relation between obesity and genetic factors
challenges associated with detecting gene-gene interactions for obesity. Monogenic obesity results from single-gene mutations that disrupt the body's ability
Genetics_of_obesity
Transmembrane protein
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Highland region in southern France
stratovolcanoes (Mounts of Cantal, Monts Dore), and small, very recent monogenic volcanoes (Chaîne des Puys, Vivarais). The entire region contains a large
Massif_Central
Study of role of genetics in the nervous system
multi-gene conditions influenced by environmental factors. Major Categories: Monogenic Neurogenic Disorders - These are mutations in a single gene and closely
Neurogenetics
Phenotypic trait influenced by a few genes
few genes. Oligogenic inheritance represents an intermediate between monogenic inheritance in which a trait is determined by a single causative gene
Oligogenic_inheritance
Group of neurodegenerative conditions
disorders, that present symptoms before the age of 18. They are typically monogenic (caused by mutations of a single gene). Their main characteristics are
Childhood_dementia
Condition involving social and behavioral differences
diagram showing overlapping clinical phenotypes in genes associated with monogenic forms of autism, dystonia, epilepsy and schizophrenia: Genes associated
Autism
Theory of plural human origins
an increased understanding of speciation in a human context, with the monogenic "Out of Africa" hypothesis and its variants being the most widely accepted
Polygenism
Study of inheritance as it occurs in human beings
Human genetics is the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical
Human_genetics
Genetic profiling of embryos prior to implantation
and the severity of the disease. PGD is available for a large number of monogenic disorders—that is, disorders due to a single gene only (autosomal recessive
Preimplantation genetic diagnosis
Preimplantation_genetic_diagnosis
Particular representation of a signal
two elements of the vector-valued monogenic signal, as it is defined for one-variable signals. However, the monogenic signal can be extended to arbitrary
Analytic_signal
Medical condition
Syndromic congenital generalized hypertrichosis includes monogenic and chromosomal disorders. The monogenic disorders may be further distinguished by autosomal
Prepubertal_hypertrichosis
Diagnosis, treatment, and prevention of illness
increasingly significant influence on medicine, as the causative genes of most monogenic genetic disorders have now been identified, and the development of techniques
Medicine
Assisted reproductive technology procedure
Those who want prenatal sex discernment. This can be used to diagnose monogenic disorders with sex linkage. It can potentially be used for sex selection
In_vitro_fertilisation
Dog breed
known as Acrodermatitis of the Bull Terrier is a rare genodermatosis monogenic autosomal inherited disease found exclusively in white Bull Terriers (including
Miniature_Bull_Terrier
Mendelian traits behave according to the model of monogenic or simple gene inheritance in which one gene corresponds to one trait. Discrete traits (as
Simple Mendelian genetics in humans
Simple_Mendelian_genetics_in_humans
Edible berry
Tomato Genetics Resource Center maintains a gene bank of wild relatives, monogenic mutants and genetic stocks. Research on processing tomatoes is also conducted
Tomato
Medical condition
myoclonic seizures and/or myoclonic astatic seizures. Some of the common monogenic causes include mutations in the genes SLC6A1 (3p25.3), CHD2 (15q26.1)
Myoclonic_astatic_epilepsy
Form of diabetes mellitus
diabetes that arise due to an abnormality in a single gene (known as monogenic forms of diabetes or "other specific types of diabetes"). These include
Type_2_diabetes
British medical researcher (born 1963)
Institute for Medical Research Cambridge Drug Discovery Institute Thesis Monogenic hypercholesterolemia in South Africans: familial hypercholesterolemia
David_C._Rubinsztein
Medical condition
mellitus (PNDM) is a newly identified and potentially treatable form of monogenic diabetes. This type of neonatal diabetes is caused by activating mutations
Permanent_neonatal_diabetes
Grouping by physical or social qualities
Civil War, broke away from the Ethnological Society of London and its monogenic stance, their underlined difference lying, relevantly, in the so-called
Race_(human_categorization)
Medical conditions more common in autistic people
diagram showing overlapping clinical phenotypes in genes associated with monogenic forms of autism, dystonia, epilepsy and schizophrenia: Genes associated
Conditions_comorbid_to_autism
Expulsion of feces from the digestive tract
be children or adults. Recent research shows that immunodeficiency and monogenic disorders are the causes in young patients with inflammatory bowel diseases
Defecation
Branch of philosophy
most powerful is the etiogically defined approach as can be found in the monogenic conception of disease which covers not only infectious agents (bacteria
Philosophy_of_medicine
Algebraic structure
A semigroup generated by a single element is said to be monogenic (or cyclic). If a monogenic semigroup is infinite then it is isomorphic to the semigroup
Semigroup
Medical condition
Deficiency of Adenosine deaminase 2 (DADA2) is a monogenic disease associated with systemic inflammation and vasculopathy that affects a wide variety
Adenosine deaminase 2 deficiency
Adenosine_deaminase_2_deficiency
Medication
S2CID 40097592. Oddi D, Crusio WE, D'Amato FR, Pietropaolo S (August 2013). "Monogenic mouse models of social dysfunction: implications for autism". Behav Brain
Naltrexone
Provides integral formulas for all derivatives of a holomorphic function
{\displaystyle \nabla f=0} , f ( r ) {\displaystyle f(r)} is called a monogenic function, the generalization of holomorphic functions to higher-dimensional
Cauchy's_integral_formula
All Latin and Greek roots beginning with G
homogeneous, hydrogen, hypogene, hypogenesis, hypogenic, hypogenous, monogenic, oogenesis, paragenesis, pathogen, polygenous, progenesis, pseudogene
List of Greek and Latin roots in English/A–G
List_of_Greek_and_Latin_roots_in_English/A–G
Genetic disorder
"Mutations in the U4 snRNA gene RNU4-2 cause one of the most prevalent monogenic neurodevelopmental disorders". Nature Medicine. 30 (8): 2165–2169. doi:10
RNU4-2_syndrome
Medical condition
of diabetes that, along with maturity onset diabetes of the young is monogenic (regulated by a single gene) and arises in the first 6 months of life
Neonatal_diabetes
Medical condition
Adult polyglucosan body disease (APBD) is a rare monogenic glycogen storage disorder (GSD type IV) caused by an inborn error of metabolism. Symptoms can
Adult polyglucosan body disease
Adult_polyglucosan_body_disease
Indian rice variety
Chaudhary, R. C. and Chauhan, J. S. 1979. Note on isozyme pattern of monogenic recessive vegetative mutant in rice. Proc. Symp. Role of Induced Mutations
Kalanamak_rice
American geneticist
framework to interpret the genome for heart attack risk which includes monogenic, somatic, and polygenic drivers of disease risk. His work has also challenged
Sekar_Kathiresan
Solutions to the euclidean Dirac equation Df = 0 are called (left) monogenic functions. Monogenic functions are special cases of harmonic spinors on a spin manifold
Clifford_analysis
diabetes that arise due to an abnormality in a single gene (known as monogenic forms of diabetes). These include maturity onset diabetes of the young
Genetic causes of type 2 diabetes
Genetic_causes_of_type_2_diabetes
Autoimmune disease in which the immune system attacks healthy tissue
i.e., cSLE, in rare cases of SLE/cSLE. The single-gene (also termed monogenic) causes of cSLE (or a cSLE-like disorder) develop in individuals before
Lupus
French scientist
scientist working at the Institut Pasteur. His group discovered the first monogenic mutations involved in autism. He is a member of the French Academy of
Thomas_Bourgeron
South Korean neuroscientist and neuroimmunologist
of IL-17 in mitigating the aberrant social behaviour in both MIA and monogenic models for ASD-like behaviour. The administration of LPS, which induces
Gloria_Choi
Rare genetic syndrome
unbalanced chromosomal translocation). Although early researchers sought a monogenic (single gene genetic disorder) explanation, recent studies have not supported
22q13_deletion_syndrome
Dog breed
known as Acrodermatitis of the Bull Terrier is a rare genodermatosis monogenic autosomal inherited disease found exclusively in white Bull Terriers (including
Bull_Terrier
Genetic disorder in Akhal-Teke horses
complete hairlessness and mild ichthyosis. The condition is inherited as a monogenic autosomal recessive trait, and affected horses typically die between a
Naked_foal_syndrome
Medical condition
Silva, Jorge Diogo (2023-09-01). "An SPG7 mutation as a novel cause of monogenic progressive muscular atrophy". Neurological Sciences. 44 (9): 3303–3305
Progressive_muscular_atrophy
x y z x x y z y y z x z z x y 2. Monogenic semigroup (index 2, period 2) x y z x y z y y z
Semigroup_with_three_elements
Genetic skin disease
Genodermatosis is a hereditary skin disease with three inherited modes including single gene inheritance, multiple gene inheritance and chromosome inheritance
Genodermatosis
Member of a group of interacting genes
quantitative characters, as opposed to the qualitative characters with monogenic or oligogenic determinism. In essence instead of two options, such as
Polygene
Family of viruses
or protein. This therapy has been found especially useful in treating monogenic disease (e.g. cystic fibrosis, X-linked SCID, alpha1-antitrypsin deficiency)
Adenoviridae
Protein-coding gene in the species Homo sapiens
Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known
RELA
bacterial angular leaf spot. Molecular breeding is usually suitable for monogenic traits, while polygenics are handled by genome-wide analysis. Genomics
Agriculture_in_Florida
Autoinflammatory disease
antinuclear antibodies, inflammatory bowel disease, Blau syndrome, adult sarcoidosis, primary Sjögren syndrome and monogenic autoinflammatory diseases
Yao_syndrome
Group of innate immune system disorders
diseases is historically called MAS, and in the context of the familial monogenic defects resulting in impaired NK (natural killer cells) or CD8+ T cell
Autoinflammatory_diseases
Possible shape of human incisor teeth
Finnish population also revealed that inheritance of incisor shoveling is monogenic. The 1540C allele of EDAR is also strongly correlated with the presence
Shovel-shaped_incisors
Medical condition
select unaffected embryos to implant. This process call be applied to any monogenic disease.[citation needed] While choroideremia is an ideal candidate for
Choroideremia
Biological molecules constituting nucleic acids
limitations of antisense oligonucleotide therapies for the treatment of monogenic disorders". Communications Medicine. 4 (1) 6. doi:10.1038/s43856-023-00419-1
Nucleotide
Numerical score aimed at predicting a trait based on variation in multiple genetic loci
it is important to realize that polygenic traits are different from monogenic traits; the latter stem from fewer genetic loci and can be detected more
Polygenic_score
Indian physician
20,000). His work on Monogenic Diabetes is well recognised. He and his colleagues have set up a National Registry for Monogenic Diabetes in India. Mohan
V._Mohan
Type of constraints for mechanical systems
system. For example, if a physical system is a holonomic system and a monogenic system, then Hamilton's principle is the necessary and sufficient condition
Holonomic_constraints
Obesity occurring as part of a medical syndrome
hypothalamic obesity). Known types of syndromic obesity include some types of monogenic obesity and: Prader Willi syndrome Bardet-Biedl syndrome Alstrom syndrome
Syndromic_obesity
Breed of dairy cattle
offspring and 209 proven male offspring. Brachyspina syndrome (BS) is a rare monogenic autosomal recessive hereditary disorder identified in this breed. Starbuck
Holstein_Friesian
Medical condition
S2CID 195676310. Garovic VD, Hilliard AA, Turner ST (November 2006). "Monogenic forms of low-renin hypertension". Nature Clinical Practice. Nephrology
Pseudohypoaldosteronism
Species of virus
VP, Kumar R, Singh SP, Kumar S, Kumar S, Singh M, Rai M (June 2014). "Monogenic recessive resistance to Pepper leaf curl virus in an interspecific cross
Pepper_leaf_curl_virus
British academic (born 1958)
Medicine at the University of Exeter and is known for his research in monogenic diabetes. He was elected a Fellow of the Royal Society in 2010. He is
Andrew_Hattersley
Medical condition
common in those affected.[citation needed] Hajdu–Cheney syndrome is a monogenic disorder. The disorder is inherited and controlled by a single pair of
Hajdu–Cheney_syndrome
Type of biological inheritance
traits in humans Simple Mendelian genetics in humans Mendelian diseases (monogenic disease) Mendelian error Particulate inheritance Punnett square William
Mendelian_inheritance
Russian chemist (1903–1971)
anniversary of the birth of R. V. Mertslin // Physico-chemical analysis of monogenic and heterogeneous multicomponent systems. Saratov: Publishing House of
Roman_Mertslin
Abnormally elevated levels of lipids or lipoproteins in the blood
Hazzard W. R.; Albers J. J.; Cooper M. N.; Motulsky A. G. "Frequency of monogenic forms of hyperlipidemia in a normal population." A19. In: "Program and
Hyperlipidemia
Non-technical introduction to genetics
These may be monogenic (caused by alterations in a single gene), polygenic (caused by alterations in multiple genes). Examples of monogenic gene disorders
Introduction_to_genetics
Genetic diversity in human populations
incidence of some monogenic diseases, and they may contribute to differences in the incidence of some common diseases. For the monogenic diseases, the frequency
Human_genetic_variation
Medical model that tailors medical practices to the individual patient
scores for common diseases identify individuals with risk equivalent to monogenic mutations". Nat Genet. 50 (9): 1219–1224. doi:10.1038/s41588-018-0183-z
Personalized_medicine
Species of flowering plant
and morphological features, the NAS and BAR types seem to be a simple monogenic variation. For this reason, it has been suggested to refer to NAS and
Barbarea_vulgaris
Fact of an action or object originating externally
Gumus Balikcioglu, Pinar (September 10, 2014). "Screening for Hormonal, Monogenic, and Syndromic Disorders in Obese Infants and Children". Pediatric Annals
Exogeny
Topics referred to by the same term
polynomial, a polynomial whose leading coefficient is one A synonym for monogenic, which has multiple uses in mathematics Monic Cecconi-Botella (1936–2025)
Monic
Range of possible values for any characteristic of human beings
single loci or multiple loci, labeling said biological traits as either monogenic or polygenic, respectively. Concerning polygenic traits it may be essential
Human_variability
Theorem about Diophantine approximations
the χ with χ(P) = 1. This gives an (antitone) Galois connection between monogenic closed subgroups of T (those with a single generator, in the topological
Kronecker's_theorem
Child conceived to provide stem cells
transplantation. It is effective against genetically detectable (mostly monogenic) diseases, e.g. Fanconi anemia, Diamond–Blackfan anemia and β-thalassemia
Savior_sibling
Protein-coding gene in the species Homo sapiens
YX (2016). "Ghrelin Receptor Mutations and Human Obesity". Genetics of Monogenic and Syndromic Obesity. Vol. 140. pp. 131–50. doi:10.1016/bs.pmbts.2016
Growth hormone secretagogue receptor
Growth_hormone_secretagogue_receptor
Abnormally low levels of albumin in the blood
0916. ISSN 1665-2681. PMID 29893696. Cil, Onur; Perwad, Farzana (2018). "Monogenic Causes of Proteinuria in Children". Frontiers in Medicine. 5: 55. doi:10
Hypoalbuminemia
Human disease
Eichler, Evan E. (2022-11-09). "Estimating the Prevalence of De Novo Monogenic Neurodevelopmental Disorders from Large Cohort Studies". Biomedicines
Okur–Chung neurodevelopmental syndrome
Okur–Chung_neurodevelopmental_syndrome
Molecular medicine Monocistronic mRNA Monoclonal antibody Monoecious plant Monogenic disorder Monohybrid Monohybrid cross Monoploid Monosomic Monosomy Morbid
Index_of_genetics_articles
Protein-coding gene in the species Homo sapiens
(2014). "Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY)". Vitamins and Hormones. 95: 407–23. doi:10
Hepatocyte nuclear factor 4 alpha
Hepatocyte_nuclear_factor_4_alpha
Range of genetic disorders which cause a person to appear to grow older faster
aging.[citation needed] All disorders within this group are thought to be monogenic, meaning they arise from mutations of a single gene. Most known PS are
Progeroid_syndromes
Form of diabetes mellitus
P, Cosentino C, Igoillo-Esteve M (2020). "A Review of Mouse Models of Monogenic Diabetes and ER Stress Signaling". In King AJ (ed.). Animal Models of
Type_1_diabetes
Type of modifier gene
genetic disease. Whereas medical genetics has tended to distinguish between monogenic traits, governed by simple, Mendelian inheritance, and quantitative traits
Human_disease_modifier_gene
Finite extension of the rationals
the field K {\displaystyle K} is called a monogenic field. An example of a number field that is not monogenic was first given by Dedekind. His example
Algebraic_number_field
MONOGENIC
MONOGENIC
MONOGENIC
MONOGENIC
Surname or Lastname
English
English : unexplained. Clearly a variant of Skaggs, also unexplained.
Girl/Female
Tamil
Specially selected \ chosen one
Boy/Male
Indian
Glory of the faith
Surname or Lastname
English
English : probably a topographic name for someone living in the Lickey Hills, southwest of Birmingham.Perhaps an altered spelling of Scottish Leckie.
Boy/Male
Hindu, Indian, Marathi, Tamil
God Sivan
Boy/Male
Indian, Punjabi, Sikh
Light of Beloved
Girl/Female
Arabic, Muslim
Aim; Goal; Plural of Hadaf; Target
Male
Iranian/Persian
Avestan name URVAKSHA means "the one who has the fat horse." In mythology, this is the name of a god avenged by his brother Kerecacpa.Â
Boy/Male
Hindu
Painter, Cheetah depending upon usage
Surname or Lastname
English (Somerset)
English (Somerset) : unexplained; perhaps a variant of Paster or Pastor.
MONOGENIC
MONOGENIC
MONOGENIC
MONOGENIC
MONOGENIC
a.
Producing only one kind of germs, or young; developing only in one way.
a.
Of or pertaining to monogenesis.
a.
Monogenic.